HRP20020336B1 - New oxabispidine compounds useful in the treatment of cardiac arrhythmias - Google Patents
New oxabispidine compounds useful in the treatment of cardiac arrhythmiasInfo
- Publication number
- HRP20020336B1 HRP20020336B1 HR20020336A HRP20020336A HRP20020336B1 HR P20020336 B1 HRP20020336 B1 HR P20020336B1 HR 20020336 A HR20020336 A HR 20020336A HR P20020336 A HRP20020336 A HR P20020336A HR P20020336 B1 HRP20020336 B1 HR P20020336B1
- Authority
- HR
- Croatia
- Prior art keywords
- aryl
- alkyl
- terminated
- optionally substituted
- halo
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 206010003119 arrhythmia Diseases 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 14
- 125000005843 halogen group Chemical group 0.000 abstract 10
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 8
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 8
- 125000001424 substituent group Chemical group 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 6
- 125000002947 alkylene group Chemical group 0.000 abstract 5
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Epoxy Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Spoj formule I, naznačen time, štoR1 predstavlja C1-12 alkil (koja alkilna skupina je po izboru supstituirana i/ili okončana s jednom ili više skupina odabranih od halo, cijano, nitro, aril, Het1, -C(O)R5a, -OR5b, -N(R6)R5c, -C(O)XR7, -C(O)N(R8)R5d i -S(O)2R9) ili R1 predstavlja -C(O)XR7, -C(O)N(R8)R5d ili -S(O)2R9;R5a do R5d neovisno predstavljaju, kod svakog pojavljivanja, H, C1-6 alkil (koja je potonja skupina po izboru supstituirana i/ili okončana s jednim ili više supstituenata odabranih od -OH, halo, cijano, nitro, aril i Het2), aril iliHet3 ili R5d, skupa s R8, predstavlja C3-6 alkilen (koja alkilenska skupina je po izboru prekinuta s nekim O atomom i/ili je po izboru supstituirana s jednom ili više C1-3 alkilnih skupina); R6 predstavlja H, C1-6 alkil (po izboru supstituiran i/iliokončan s jednim ili više supstituenata odabranihod -OH, halo, cijano, nitro i aril), aril, -C(O)R10a, -C(O)OR10b ili -C(O)N(H)R10c;R10a, R10b i R10c neovisno predstavljaju C1-6 alkil (po izboru supstituiran i/ili okončan s jednim ili više supstituenata odabranih od -OH, halo, cijano, nitro i aril), aril, ili R10a predstavlja H; R7 predstavlja C1-12 alkil (po izboru supstituiran i/ili okončan s jednim ili više supstituenata odabranih od -OH, halo, cijano, nitro, aril, C1-6 alkoksi i Het4);R8 predstavlja H, C1-12 alkil, C1-6 alkoksi (koje su potonje dvije skupina po izboru supstituirane i/iliokončane s jednim ili više supstituenata odabranih od -OH, halo, cijano, nitro, C1-4 alkil i C1-4 alkoksi), -D-aril, -D-ariloksi, -D-Het5, -D-N(H)C(O)R11a, -D-S(O)2R12a, -D-C(O)R11b, -D-C(O)OR12b, -D-C(O)N(R11c)R11d, ili R8, skupa s R5d, predstavljaC3-6 alkilene (koja alkilenska skupina je po izboru prekinuta s O atomom i/ili je po izboru supstituirana s jednom ili više C1-3 alkilnih skupina); R11a do R11d neovisno predstavljaju H, C1-6 alkil (po izboru supstituiran i/ili okončan s jednim ili više supstituenata odabranih od -OH, halo, cijano,nitro i aril), aril, ili R11c i R11d skupa predstavljaju C3-6 alkilen; R9, R12a i R12b neovisno predstavljaju C1-6 alkil (po izboru supstituiran i/ili okončan s jednim ili više supstituenata odabranih od -OH, halo, cijano, nitro i aril) ili aril; D predstavlja izravnu vezu ili C1-6 alkilen; X predstavlja O ili S; R2 predstavlja H, halo, C1-6 alkil, -OR13, -E-N(R14)R15 ili, skupa s R3, predstavlja=O; R3 predstavlja H, C1-6 alkil ili skupa s R2, predstavlja =O; R13 predstavlja H, C1-6 alkil, -E-aril, -E-Het6, -C(O)R16a, -C(O)OR16b ili -C(O)N(R17a)R17b;R14 predstavlja H, C1-6 alkil, -E-aril, -E-Het6, -C(O)R16a, -C(O)OR16b, -S(O)2R16c, -[C(O)]pN(R17a)R17b ili -C(NH)NH2;R15 predstavlja H, C1-6 alkil, -E-aril ili -C(O)R16d;R16a do R16d neovisnopredstavljaju, kod svakog pojavljivanja kada se koriste ovdje, C1-6 alkil (po izboru supstituiran i/ili okončan s jednim ili više supstituenata odabranih od halo, aril i Het7), aril, Het8, ili R16a iR16d neovisno predstavljaju H; R17a i R17b neovisno predstavljaju, kod svakog pojavljivanja kada se koriste
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9903759A SE9903759D0 (sv) | 1999-10-18 | 1999-10-18 | Pharmaceutically active compounds |
PCT/SE2000/001994 WO2001028992A2 (en) | 1999-10-18 | 2000-10-13 | New oxabispidine compounds useful in the treatment of cardiac arrhythmias |
Publications (2)
Publication Number | Publication Date |
---|---|
HRP20020336A2 HRP20020336A2 (en) | 2004-02-29 |
HRP20020336B1 true HRP20020336B1 (en) | 2006-02-28 |
Family
ID=20417401
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20020336A HRP20020336B1 (en) | 1999-10-18 | 2002-04-16 | New oxabispidine compounds useful in the treatment of cardiac arrhythmias |
Country Status (41)
Country | Link |
---|---|
US (6) | US6559143B1 (hr) |
EP (2) | EP1559717A3 (hr) |
JP (3) | JP3973906B2 (hr) |
KR (1) | KR100796142B1 (hr) |
CN (2) | CN100379743C (hr) |
AP (1) | AP1536A (hr) |
AR (2) | AR026064A1 (hr) |
AT (1) | ATE292134T1 (hr) |
AU (1) | AU769513B2 (hr) |
BG (1) | BG65785B1 (hr) |
BR (1) | BR0014804A (hr) |
CA (1) | CA2386910A1 (hr) |
CO (1) | CO5271655A1 (hr) |
CU (1) | CU23210A3 (hr) |
CZ (1) | CZ20021328A3 (hr) |
DE (1) | DE60019158T2 (hr) |
DK (1) | DK1235831T3 (hr) |
EA (1) | EA005319B1 (hr) |
EE (1) | EE04854B1 (hr) |
ES (1) | ES2239047T3 (hr) |
HK (1) | HK1049003B (hr) |
HR (1) | HRP20020336B1 (hr) |
HU (1) | HUP0204085A3 (hr) |
IL (5) | IL149108A0 (hr) |
IS (2) | IS2224B (hr) |
MX (1) | MXPA02003848A (hr) |
MY (1) | MY130661A (hr) |
NO (1) | NO327977B1 (hr) |
NZ (2) | NZ518156A (hr) |
OA (1) | OA12067A (hr) |
PL (1) | PL354970A1 (hr) |
PT (1) | PT1235831E (hr) |
RS (1) | RS50760B (hr) |
SE (1) | SE9903759D0 (hr) |
SI (1) | SI1235831T1 (hr) |
SK (1) | SK286723B6 (hr) |
TR (1) | TR200201059T2 (hr) |
TW (1) | TWI283680B (hr) |
UA (1) | UA75052C2 (hr) |
WO (1) | WO2001028992A2 (hr) |
ZA (1) | ZA200202575B (hr) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI229674B (en) | 1998-12-04 | 2005-03-21 | Astra Pharma Prod | Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses |
SE9902270D0 (sv) * | 1999-06-16 | 1999-06-16 | Astra Ab | Pharmaceutically active compounds |
SE9903759D0 (sv) * | 1999-10-18 | 1999-10-18 | Astra Ab | Pharmaceutically active compounds |
AR030756A1 (es) * | 2000-10-02 | 2003-09-03 | Astrazeneca Ab | Compuesto de oxabispidina util en el tratamiento de arritmias cardiacas |
TWI259836B (en) * | 2001-04-12 | 2006-08-11 | Astrazeneca Ab | Modified release formulation suitable for antiarrhythmic compounds |
SE0101329D0 (sv) * | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | Pharmaceutical formulation |
SE0101324D0 (sv) * | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | New process |
SE0101323D0 (sv) * | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | New process |
SE0101327D0 (sv) | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | New crystalline forms |
BR0214225A (pt) * | 2001-11-22 | 2004-09-21 | Astrazeneca Ab | Processos para a preparação e para a formação de um composto, e, composto |
SE0201374D0 (sv) * | 2002-05-06 | 2002-05-06 | Astrazeneca Ab | Pharmaceutical combination |
SE0201373D0 (sv) * | 2002-05-06 | 2002-05-06 | Astrazeneca Ab | Combination therapy |
SE0201662D0 (sv) * | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | Pharmaceutical combination |
GB0223712D0 (en) * | 2002-10-14 | 2002-11-20 | Astrazeneca Ab | Chemical intermediate |
SE0401540D0 (sv) | 2004-06-15 | 2004-06-15 | Astrazeneca Ab | New compounds |
SE0401539D0 (sv) | 2004-06-15 | 2004-06-15 | Astrazeneca Ab | New compounds |
AU2006258293B2 (en) * | 2005-06-13 | 2010-06-17 | Astrazeneca Ab | New oxabispidine compounds for the treatment of cardiac arrhythmias |
WO2006137771A1 (en) * | 2005-06-20 | 2006-12-28 | Astrazeneca Ab | Process for the preparation of sulfonic acid salts of oxabispidines |
AR053901A1 (es) * | 2005-06-20 | 2007-05-23 | Astrazeneca Ab | Formas fisicas de oxabispidinas n,n'- disustituidas |
EP1896486A4 (en) * | 2005-06-20 | 2010-11-03 | Astrazeneca Ab | PROCESS FOR THE PREPARATION OF 3,7-DIHYDROXY-1,5-DIAZACYCLOOCTANESE |
KR20080028435A (ko) * | 2005-06-20 | 2008-03-31 | 아스트라제네카 아베 | N,n’-이치환된 옥사비스피딘의 제조 방법 |
CN1330636C (zh) * | 2005-09-26 | 2007-08-08 | 鲁南制药集团股份有限公司 | 盐酸替罗非班中间体的合成方法 |
TW200734342A (en) * | 2005-12-15 | 2007-09-16 | Astrazeneca Ab | New compounds for the treatment of cardiac arrhythmias |
TW201004963A (en) * | 2008-07-03 | 2010-02-01 | Targacept Inc | Derivatives of oxabispidine as neuronal nicotinic acetylcholine receptor ligands |
GB2495308B (en) * | 2011-10-05 | 2014-09-10 | John Royce | Method and apparatus for cleaning a filter |
SG10201802911RA (en) | 2013-03-15 | 2018-05-30 | Global Blood Therapeutics Inc | Compounds and uses thereof for the modulation of hemoglobin |
EA201992707A1 (ru) | 2013-11-18 | 2020-06-30 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
US10231970B2 (en) | 2014-09-30 | 2019-03-19 | NV Heterocycles | Methods of producing heteropolycycles via bis-epoxidation |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
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US3196154A (en) * | 1962-05-17 | 1965-07-20 | Sterling Drug Inc | 3-substituted-9-methyl-3, 9-diazabicyclo [3.3.1] nonanes |
US3503939A (en) | 1967-03-29 | 1970-03-31 | Du Pont | Polyamides from heterocyclic diamines |
CH488048A (de) | 1969-06-12 | 1970-03-31 | Inventa Ag | Verfahren zur Herstellung von Polyesterfasern mit verbesserter Gummihaftung |
JPS5772977A (en) * | 1980-10-23 | 1982-05-07 | Dainippon Ink & Chem Inc | Fluorine-containing diepoxy compound and its preparation |
DE3112055A1 (de) * | 1981-03-27 | 1982-10-07 | Basf Ag, 6700 Ludwigshafen | Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel |
US4533713A (en) * | 1983-05-06 | 1985-08-06 | Minnesota Mining And Manufacturing Company | Fluoroaliphaticsulfonamides containing oxirane groups and/or N-β-hydroxyalkylene groups |
FI67320C (fi) * | 1983-05-09 | 1985-03-11 | Partek Ab | Foerfarande och glidgjutanordning foer gjutning av betongstycken |
JPS6284071A (ja) * | 1985-10-07 | 1987-04-17 | Kanegafuchi Chem Ind Co Ltd | 新規グリシジル化合物及びその製造方法 |
JPS6284070A (ja) | 1985-10-07 | 1987-04-17 | Kanegafuchi Chem Ind Co Ltd | 新規なグリシジル化合物及びその製造法 |
DE3732094A1 (de) | 1987-09-24 | 1989-04-06 | Basf Ag | Bispidinderivate als klasse iii-antiarrhythmika |
US5140033A (en) | 1989-04-03 | 1992-08-18 | Bayer Aktiengesellschaft | Antibacterial 5-alkylquinolonecarboxylic acids |
US5110933A (en) | 1989-11-13 | 1992-05-05 | Board Of Regents Of Oklahoma State University | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof |
FR2664270B1 (fr) * | 1990-07-09 | 1994-04-08 | Norsolor Sa | Nouveaux composes (meth)acryliques porteurs de fonction thiocyanate, leur procede de preparation et leur application a l'obtention de nouveaux polymeres. |
JP2602745B2 (ja) * | 1991-06-26 | 1997-04-23 | 花王株式会社 | フレキシブルディスク用センターハブのピッキング装置 |
US5468858A (en) * | 1993-10-28 | 1995-11-21 | The Board Of Regents Of Oklahoma State University Physical Sciences | N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents |
US5831099A (en) * | 1995-03-10 | 1998-11-03 | The United States Of America As Represented By The Secretary Of The Army | Compounds of 1,5-disubstituted-3,7 diaza bicyclo 3.3.0! octanes and products containing the same |
SE9704709D0 (sv) * | 1997-12-17 | 1997-12-17 | Astra Ab | Pharmaceutically active compounds |
SE9803517D0 (sv) * | 1998-10-15 | 1998-10-15 | Astra Ab | Pharmaceutical preparation |
SK13422001A3 (sk) | 1999-04-09 | 2002-05-09 | Astrazeneca Ab | Adamantánové deriváty |
SE9902270D0 (sv) * | 1999-06-16 | 1999-06-16 | Astra Ab | Pharmaceutically active compounds |
SE9903759D0 (sv) | 1999-10-18 | 1999-10-18 | Astra Ab | Pharmaceutically active compounds |
SE9904765D0 (sv) * | 1999-12-23 | 1999-12-23 | Astra Ab | Pharmaceutically-useful compounds |
AR030756A1 (es) * | 2000-10-02 | 2003-09-03 | Astrazeneca Ab | Compuesto de oxabispidina util en el tratamiento de arritmias cardiacas |
-
1999
- 1999-10-18 SE SE9903759A patent/SE9903759D0/xx unknown
-
2000
- 2000-10-06 TW TW089120910A patent/TWI283680B/zh not_active IP Right Cessation
- 2000-10-13 PL PL00354970A patent/PL354970A1/xx not_active Application Discontinuation
- 2000-10-13 AT AT00971960T patent/ATE292134T1/de not_active IP Right Cessation
- 2000-10-13 SK SK506-2002A patent/SK286723B6/sk not_active IP Right Cessation
- 2000-10-13 TR TR2002/01059T patent/TR200201059T2/xx unknown
- 2000-10-13 WO PCT/SE2000/001994 patent/WO2001028992A2/en active Application Filing
- 2000-10-13 EA EA200200390A patent/EA005319B1/ru not_active IP Right Cessation
- 2000-10-13 EP EP05006781A patent/EP1559717A3/en not_active Withdrawn
- 2000-10-13 OA OA1200200113A patent/OA12067A/en unknown
- 2000-10-13 EP EP00971960A patent/EP1235831B1/en not_active Expired - Lifetime
- 2000-10-13 MX MXPA02003848A patent/MXPA02003848A/es active IP Right Grant
- 2000-10-13 ES ES00971960T patent/ES2239047T3/es not_active Expired - Lifetime
- 2000-10-13 CZ CZ20021328A patent/CZ20021328A3/cs unknown
- 2000-10-13 CN CNB00816231XA patent/CN100379743C/zh not_active Expired - Fee Related
- 2000-10-13 JP JP2001531792A patent/JP3973906B2/ja not_active Expired - Fee Related
- 2000-10-13 EE EEP200200203A patent/EE04854B1/xx not_active IP Right Cessation
- 2000-10-13 AP APAP/P/2002/002471A patent/AP1536A/en active
- 2000-10-13 NZ NZ518156A patent/NZ518156A/en unknown
- 2000-10-13 AU AU10691/01A patent/AU769513B2/en not_active Ceased
- 2000-10-13 RS YUP-294/02A patent/RS50760B/sr unknown
- 2000-10-13 SI SI200030681T patent/SI1235831T1/xx unknown
- 2000-10-13 NZ NZ531260A patent/NZ531260A/en unknown
- 2000-10-13 PT PT00971960T patent/PT1235831E/pt unknown
- 2000-10-13 KR KR1020027004902A patent/KR100796142B1/ko not_active IP Right Cessation
- 2000-10-13 CN CNA2008100058488A patent/CN101265262A/zh active Pending
- 2000-10-13 DE DE60019158T patent/DE60019158T2/de not_active Expired - Lifetime
- 2000-10-13 BR BR0014804-0A patent/BR0014804A/pt not_active IP Right Cessation
- 2000-10-13 UA UA2002043168A patent/UA75052C2/uk unknown
- 2000-10-13 DK DK00971960T patent/DK1235831T3/da active
- 2000-10-13 CA CA002386910A patent/CA2386910A1/en not_active Abandoned
- 2000-10-13 HU HU0204085A patent/HUP0204085A3/hu unknown
- 2000-10-13 IL IL14910800A patent/IL149108A0/xx unknown
- 2000-10-16 US US09/688,251 patent/US6559143B1/en not_active Expired - Fee Related
- 2000-10-16 MY MYPI20004850A patent/MY130661A/en unknown
- 2000-10-17 AR ARP000105452A patent/AR026064A1/es active IP Right Grant
- 2000-10-17 CO CO00078740A patent/CO5271655A1/es not_active Application Discontinuation
-
2002
- 2002-04-02 ZA ZA200202575A patent/ZA200202575B/en unknown
- 2002-04-05 BG BG106588A patent/BG65785B1/bg unknown
- 2002-04-11 IL IL183854A patent/IL183854A0/en unknown
- 2002-04-11 IL IL149108A patent/IL149108A/en not_active IP Right Cessation
- 2002-04-16 HR HR20020336A patent/HRP20020336B1/xx not_active IP Right Cessation
- 2002-04-16 CU CU20020079A patent/CU23210A3/es not_active IP Right Cessation
- 2002-04-17 IS IS6346A patent/IS2224B/is unknown
- 2002-04-17 NO NO20021811A patent/NO327977B1/no not_active IP Right Cessation
- 2002-12-12 US US10/317,195 patent/US7164017B2/en not_active Expired - Fee Related
-
2003
- 2003-02-18 HK HK03101241.2A patent/HK1049003B/zh not_active IP Right Cessation
- 2003-04-02 AR ARP030101150A patent/AR039226A2/es unknown
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2006
- 2006-03-22 US US11/385,833 patent/US7772229B2/en not_active Expired - Fee Related
- 2006-03-22 US US11/385,861 patent/US20060166980A1/en not_active Abandoned
- 2006-08-23 JP JP2006226089A patent/JP2006342182A/ja active Pending
- 2006-12-18 US US11/640,417 patent/US7351821B2/en not_active Expired - Fee Related
- 2006-12-27 IS IS8586A patent/IS8586A/is unknown
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2007
- 2007-03-28 JP JP2007083302A patent/JP2007204486A/ja active Pending
- 2007-06-11 IL IL183852A patent/IL183852A0/en unknown
- 2007-06-11 IL IL183853A patent/IL183853A0/en unknown
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2009
- 2009-09-01 US US12/585,029 patent/US20090326221A1/en not_active Abandoned
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