HK52487A - Process and intermediates for production of 1,1-dioxopenicillanoyloxymethyl 6-(2-amino-2-phenylacetamido)penicillanates - Google Patents

Process and intermediates for production of 1,1-dioxopenicillanoyloxymethyl 6-(2-amino-2-phenylacetamido)penicillanates

Info

Publication number
HK52487A
HK52487A HK524/87A HK52487A HK52487A HK 52487 A HK52487 A HK 52487A HK 524/87 A HK524/87 A HK 524/87A HK 52487 A HK52487 A HK 52487A HK 52487 A HK52487 A HK 52487A
Authority
HK
Hong Kong
Prior art keywords
acid
formula
compound
mixture
reaction
Prior art date
Application number
HK524/87A
Other languages
German (de)
English (en)
French (fr)
Inventor
Vytautas John Jasys
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of HK52487A publication Critical patent/HK52487A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/28—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with modified 2-carboxyl group
    • C07D499/32—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Cephalosporin Compounds (AREA)
HK524/87A 1981-03-23 1987-07-09 Process and intermediates for production of 1,1-dioxopenicillanoyloxymethyl 6-(2-amino-2-phenylacetamido)penicillanates HK52487A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24645681A 1981-03-23 1981-03-23

Publications (1)

Publication Number Publication Date
HK52487A true HK52487A (en) 1987-07-17

Family

ID=22930766

Family Applications (1)

Application Number Title Priority Date Filing Date
HK524/87A HK52487A (en) 1981-03-23 1987-07-09 Process and intermediates for production of 1,1-dioxopenicillanoyloxymethyl 6-(2-amino-2-phenylacetamido)penicillanates

Country Status (32)

Country Link
EP (1) EP0061274B1 (en, 2012)
JP (3) JPS57169493A (en, 2012)
KR (1) KR860001368B1 (en, 2012)
AU (1) AU531892B2 (en, 2012)
BG (2) BG37380A3 (en, 2012)
CA (1) CA1213581A (en, 2012)
CS (1) CS227345B2 (en, 2012)
DD (1) DD202163A5 (en, 2012)
DE (1) DE3267505D1 (en, 2012)
DK (3) DK162392C (en, 2012)
EG (1) EG15803A (en, 2012)
ES (2) ES510655A0 (en, 2012)
FI (1) FI74284C (en, 2012)
GB (1) GB2095250A (en, 2012)
GR (1) GR75935B (en, 2012)
GT (1) GT198274393A (en, 2012)
HK (1) HK52487A (en, 2012)
HU (2) HU187667B (en, 2012)
IE (1) IE52835B1 (en, 2012)
IL (1) IL65308A (en, 2012)
IN (1) IN159362B (en, 2012)
MY (1) MY8700499A (en, 2012)
NO (1) NO159658C (en, 2012)
NZ (1) NZ200066A (en, 2012)
PH (1) PH17602A (en, 2012)
PL (3) PL139261B1 (en, 2012)
PT (1) PT74621B (en, 2012)
RO (2) RO84278B (en, 2012)
SG (1) SG23387G (en, 2012)
SU (2) SU1277898A3 (en, 2012)
YU (2) YU42761B (en, 2012)
ZA (1) ZA821899B (en, 2012)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0084730A1 (en) * 1982-01-22 1983-08-03 Beecham Group Plc Esters of penicillin derivatives with beta-lactamase inhibitors, their preparation and their use
PH20068A (en) * 1982-12-06 1986-09-18 Pfizer Process and intermediates for sultamicillin and analogs
GB8808701D0 (en) * 1988-04-13 1988-05-18 Erba Carlo Spa Beta-lactam derivatives
ES2039299B1 (es) * 1991-10-04 1994-05-16 Asturpharma S A Procedimiento de obtencion de esteres de acido 1,1-dioxopenicilanico y sus sales.
ES2100125B1 (es) * 1995-06-02 1998-04-01 Asturpharma S A Procedimiento de preparacion de esteres de metanodiol de acido dioxopenicilanico.
CN112724162B (zh) * 2020-12-28 2022-06-10 华南农业大学 一种阿莫西林-舒巴坦杂合分子的合成方法及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE881675A (fr) * 1979-02-13 1980-08-12 Leo Pharm Prod Ltd B-lactames derives de l'acide penicillanique leur preparation et leurs utilisations therapeutiques
IE49880B1 (en) * 1979-02-13 1986-01-08 Leo Pharm Prod Ltd Penicillin derivatives
SE449103B (sv) * 1979-03-05 1987-04-06 Pfizer Sett att framstella penicillansyra-1,1-dioxid samt estrar derav
ZA80646B (en) * 1979-03-05 1981-02-25 Pfizer Process and intermediates for penicillanic acid,1,1-dioxide and esters thereof
IE50650B1 (en) * 1979-10-11 1986-06-11 Leo Pharm Prod Ltd Method for producing penicillanic acid derivatives

Also Published As

Publication number Publication date
KR830009113A (ko) 1983-12-17
YU181084A (en) 1987-06-30
RO87946B (ro) 1985-12-02
ES8305768A1 (es) 1983-04-16
EP0061274A1 (en) 1982-09-29
PL139261B1 (en) 1987-01-31
SG23387G (en) 1987-07-10
CS227345B2 (en) 1984-04-16
DD202163A5 (de) 1983-08-31
GR75935B (en, 2012) 1984-08-02
IE52835B1 (en) 1988-03-16
DE3267505D1 (en) 1986-01-02
PL240663A1 (en) 1983-09-12
RO84278A (ro) 1984-05-23
NO820898L (no) 1982-09-24
KR860001368B1 (ko) 1986-09-17
NZ200066A (en) 1985-08-16
BG38939A3 (en) 1986-03-14
EG15803A (en) 1990-08-30
PL240664A1 (en) 1983-09-12
RO84278B (ro) 1984-07-30
YU42761B (en) 1988-12-31
MY8700499A (en) 1987-12-31
HUT34985A (en) 1985-05-28
DK162392C (da) 1992-03-09
GT198274393A (es) 1983-09-08
DK121491A (da) 1991-06-21
DK167119B1 (da) 1993-08-30
ZA821899B (en) 1983-01-26
JPS63146886A (ja) 1988-06-18
ES510655A0 (es) 1983-04-16
EP0061274B1 (en) 1985-11-21
HU187667B (en) 1986-02-28
YU43585B (en) 1989-08-31
AU531892B2 (en) 1983-09-08
GB2095250A (en) 1982-09-29
FI820991L (fi) 1982-09-24
FI74284C (fi) 1988-01-11
BG37380A3 (en) 1985-05-15
JPH0331717B2 (en, 2012) 1991-05-08
DK162392B (da) 1991-10-21
IE820659L (en) 1982-09-23
DK165746B (da) 1993-01-11
HU189917B (en) 1986-08-28
AU8176482A (en) 1982-11-04
PT74621B (en) 1984-11-26
SU1277898A3 (ru) 1986-12-15
DK21892A (da) 1992-02-20
ES518970A0 (es) 1984-03-01
YU61982A (en) 1985-03-20
PH17602A (en) 1984-10-05
PL235578A1 (en) 1983-06-20
FI74284B (fi) 1987-09-30
SU1277897A3 (ru) 1986-12-15
JPS57169493A (en) 1982-10-19
PL134250B1 (en) 1985-08-31
PT74621A (en) 1982-04-01
IL65308A0 (en) 1982-05-31
ES8403132A1 (es) 1984-03-01
DK165746C (da) 1993-06-07
DK21892D0 (da) 1992-02-20
IN159362B (en, 2012) 1987-05-09
CA1213581A (en) 1986-11-04
PL138851B1 (en) 1986-11-29
NO159658C (no) 1989-01-25
IL65308A (en) 1985-03-31
JPS6345287A (ja) 1988-02-26
DK127182A (da) 1982-09-24
DK121491D0 (da) 1991-06-21
NO159658B (no) 1988-10-17
RO87946A (ro) 1985-12-20

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Legal Events

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