HK1220452A1 - Opioid and opioid-like compounds and uses thereof - Google Patents
Opioid and opioid-like compounds and uses thereof Download PDFInfo
- Publication number
- HK1220452A1 HK1220452A1 HK16108452.6A HK16108452A HK1220452A1 HK 1220452 A1 HK1220452 A1 HK 1220452A1 HK 16108452 A HK16108452 A HK 16108452A HK 1220452 A1 HK1220452 A1 HK 1220452A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- compound
- compounds
- opioid
- mmol
- lps
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38084102P | 2002-05-17 | 2002-05-17 | |
| US380841P | 2002-05-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1220452A1 true HK1220452A1 (en) | 2017-06-09 |
Family
ID=29550023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16108452.6A HK1220452A1 (en) | 2002-05-17 | 2016-07-18 | Opioid and opioid-like compounds and uses thereof |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP2987788A1 (https=) |
| JP (3) | JP5438250B2 (https=) |
| CN (2) | CN103405431B (https=) |
| AU (2) | AU2003234621A1 (https=) |
| CA (1) | CA2486157C (https=) |
| HK (1) | HK1220452A1 (https=) |
| MX (1) | MXPA04011327A (https=) |
| TW (1) | TWI275591B (https=) |
| WO (1) | WO2003097608A2 (https=) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2521914Y2 (ja) | 1988-12-23 | 1997-01-08 | エヌティエヌ株式会社 | 大型転がり軸受 |
| US7923454B2 (en) * | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US20040204862A1 (en) | 2003-04-11 | 2004-10-14 | Wainer Irving W. | Computer-based model for identification and characterization for non-competitive inhibitors of nicotinic acetylcholine receptors and related ligand-gated ion channel receptors |
| CA2566445C (en) * | 2004-05-12 | 2016-02-02 | The Government Of The United States As Represented By The Secretary, Department Of Health And Human Services | Methods related to the treatment of neurodegenerative and inflammatory conditions |
| AU2005244401B2 (en) | 2004-05-14 | 2009-01-22 | Green Cross Corp. | Neuroprotective properties of dextrorotatory morphinans |
| SA07280459B1 (ar) * | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| FI3825306T3 (fi) | 2007-05-01 | 2023-08-23 | Concert Pharmaceuticals Inc | Morfinaaniyhdisteitä |
| EP2183228B1 (en) | 2007-07-26 | 2014-08-20 | Vitae Pharmaceuticals, Inc. | CYCLIC INHIBITORS OF 11ß -HYDROXYSTERIOD DEHYDROGENASE 1 |
| AR069207A1 (es) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
| CL2008003407A1 (es) | 2007-11-16 | 2010-01-11 | Boehringer Ingelheim Int | Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1. |
| CN102908339A (zh) * | 2007-11-23 | 2013-02-06 | 格吕伦塔尔有限公司 | 他喷他多组合物 |
| CA2708303A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
| TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| WO2009094169A1 (en) | 2008-01-24 | 2009-07-30 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8598160B2 (en) | 2008-02-15 | 2013-12-03 | Vitae Pharmaceuticals, Inc. | Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| CL2009001059A1 (es) | 2008-05-01 | 2010-11-12 | Boehringer Ingelheim Int | Compuestos derivados de 1,3-oxazin-2-ona-3,6 sustituidos, inhibidores de la actividad de la 11-beta-hidroxiesteroide deshidrogenasa i; composicion farmaceutica que los comprende; utiles en el tratamiento de enfermedades tales como diabetes mellitus, entre otras. |
| AR071236A1 (es) | 2008-05-01 | 2010-06-02 | Vitae Pharmaceuticals Inc | Inhibidores ciclicos de la 11beta-hidroxiesteroide deshidrogenasa 1 |
| WO2009134387A1 (en) | 2008-05-01 | 2009-11-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8765780B2 (en) | 2008-05-13 | 2014-07-01 | Boehringer Ingelheim International Gmbh | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
| US8846668B2 (en) | 2008-07-25 | 2014-09-30 | Vitae Pharmaceuticals, Inc. | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| WO2010011314A1 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1 |
| EP2334678B1 (en) | 2008-09-19 | 2012-12-26 | Concert Pharmaceuticals Inc. | Morphinan compounds |
| CA2744946A1 (en) | 2009-02-04 | 2010-08-12 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
| UA109255C2 (ru) | 2009-04-30 | 2015-08-10 | Берінгер Інгельхайм Інтернешнл Гмбх | Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1 |
| EP2440537A1 (en) | 2009-06-11 | 2012-04-18 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
| US8829020B2 (en) | 2009-07-16 | 2014-09-09 | Mallinckrodt Llc | Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers |
| AR078887A1 (es) | 2009-11-06 | 2011-12-07 | Boehringer Ingelheim Int | Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen. |
| WO2011137734A1 (en) | 2010-05-03 | 2011-11-10 | Tsh Biopharm Company, Limited | Pharmaceutical composition and method for treating hypertension |
| US8933072B2 (en) | 2010-06-16 | 2015-01-13 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
| JP5813106B2 (ja) | 2010-06-25 | 2015-11-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 代謝障害の処置のための11−β−HSD1のインヒビターとしてのアザスピロヘキサノン |
| PH12013500808A1 (en) | 2010-11-02 | 2015-10-07 | Boehringer Ingelheim Int | Pharmaceutical combinations for the treatment of metabolic disorders |
| TWI537258B (zh) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物 |
| US8987293B2 (en) * | 2010-12-23 | 2015-03-24 | Phoenix Pharmalabs, Inc. | Morphinans useful as analgesics |
| JP2014524438A (ja) | 2011-08-17 | 2014-09-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | インデノピリジン誘導体 |
| CN102731399B (zh) * | 2012-07-06 | 2013-11-06 | 启东东岳药业有限公司 | 高纯度3-甲氧基-9α,13α,14α吗啡喃盐酸盐的制备方法 |
| CN103254131A (zh) * | 2013-04-23 | 2013-08-21 | 苏州谷力生物科技有限公司 | 一种右美沙芬原料药的精制工艺 |
| GB201308440D0 (en) * | 2013-05-10 | 2013-06-19 | Dalgleish Angus | Therapeutic |
| JP6248711B2 (ja) | 2014-03-06 | 2017-12-20 | 株式会社デンソー | 回転電機の固定子 |
| US9757372B2 (en) | 2015-03-25 | 2017-09-12 | Taiwanj Pharmaceuticals Co., Ltd. | Toll-like receptor 4 antagonists and use in autoimmune liver diseases |
| EP3445363A1 (en) | 2016-04-22 | 2019-02-27 | Taiwanj Pharmaceuticals Co., Ltd. | Nalmefene, naltrexone or derivatives thereof for use in treating (non)-alcoholic steatohepatitis or non-alcoholic fatty liver disease |
| EP3565556A4 (en) * | 2017-01-05 | 2020-06-10 | Taiwanj Pharmaceuticals Co., Ltd. | MORPHINE DERIVATIVES AND COMPOSITIONS THERE FOR TREATING AUTOIMMUNE, INFLAMMATION OR INFECTIOUS DISEASES |
| CN107157998A (zh) * | 2017-05-26 | 2017-09-15 | 张灏 | 右美沙芬的新用途 |
| CA3130708A1 (en) * | 2019-02-19 | 2020-08-27 | Robert Barsotti | Solutions and methods for organ preservation |
| CN119977886B (zh) * | 2025-02-13 | 2025-08-22 | 安徽益普克医药科技发展有限公司 | 一种葡萄糖酸喷他佐辛苯甲酸酯及其制备方法与用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3275638A (en) | 1966-09-27 | Chjcoo- | ||
| NL127995C (https=) | 1963-12-20 | Geigy Ag J R | ||
| GB1038732A (en) | 1963-12-31 | 1966-08-10 | Hoffmann La Roche | Morphinan derivatives and a process for the manufacture thereof |
| IE34235B1 (en) | 1969-06-04 | 1975-03-19 | Acf Chemiefarma Nv | 6,7-benzomorphans and their preparation |
| CA919668A (en) | 1970-06-20 | 1973-01-23 | Murakami Masuo | Morphinan derivatives |
| BE788478A (fr) | 1971-09-08 | 1973-03-06 | Bristol Myers Co | Procede de preparation de composes analgesiques |
| DE2238839A1 (de) * | 1972-08-07 | 1974-02-14 | Boehringer Sohn Ingelheim | Neue morphinon-derivate, deren saeureadditionssalze, verfahren zu ihrer herstellung sowie ihre verwendung zur herstellung von arzneimitteln |
| DE2259979A1 (de) | 1972-12-07 | 1974-06-12 | Bayer Ag | Benzomorphan-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| JPS514175A (en) * | 1974-07-01 | 1976-01-14 | Yamanouchi Pharma Co Ltd | Morufuinanjudotaino goseiho |
| GB1513961A (en) | 1975-02-25 | 1978-06-14 | Acf Chemiefarma Nv | 6,7-benzomorphans method for their preparation and intermediates |
| US4029798A (en) | 1975-06-02 | 1977-06-14 | Sumitomo Chemical Company, Limited | Analgetic composition |
| GB1575009A (en) | 1976-06-21 | 1980-09-17 | Acf Chemiefarma Nv | 6,7-benzomorphan derivatives |
| US4161597A (en) * | 1976-12-20 | 1979-07-17 | Research Corporation | N-alkyl-14-hydroxymorphinans and derivatives |
| CA1093070A (en) | 1978-02-10 | 1981-01-06 | Michael P. Kotick | 8.beta.-ALKYL-SUBSTITUTED MORPHINAN-6-ONE COMPOUNDS |
| US4272541A (en) | 1978-06-02 | 1981-06-09 | Miles Laboratories, Inc. | 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them |
| US4267182A (en) * | 1979-01-16 | 1981-05-12 | The United States Of America As Represented By The Secretary Of The Army | Narcotic antagonists in the therapy of shock |
| US4228285A (en) | 1979-02-28 | 1980-10-14 | Bristol-Myers Company | 14-Hydroxy-6-oxamorphinans and 14-hydroxy-6-oxaisomorphinans |
| US4388463A (en) | 1981-07-16 | 1983-06-14 | The United States Of America As Represented By Secretary Of The Department Of Health And Human Services | 6-Keto-morphinan analgesics |
| US4390699A (en) | 1981-07-16 | 1983-06-28 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | 6-Keto-morphinans belonging to the 14-hydroxy-series |
| IN163125B (https=) | 1985-01-08 | 1988-08-13 | Alkaloida Vegyeszeti Gyar | |
| HU196376B (en) | 1985-05-23 | 1988-11-28 | Sandoz Ag | Process for preparing morphinane derivatives and pharmaceutical compositions containing such compounds |
| US4673679A (en) | 1986-05-14 | 1987-06-16 | E. I. Du Pont De Nemours And Company | Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration |
| US4912114A (en) | 1988-03-18 | 1990-03-27 | Sandoz Ltd. | Morphinan derivatives |
| FR2636330B1 (fr) | 1988-09-13 | 1990-11-30 | Sanofi Sa | Procede de preparation de derives de morphinane |
| US4863928A (en) * | 1989-01-04 | 1989-09-05 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for arthritic and inflammatory diseases |
| GB9103302D0 (en) * | 1991-02-16 | 1991-04-03 | Smithkline Beecham Plc | Pharmaceutical formulations |
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| US5607941A (en) | 1992-06-26 | 1997-03-04 | Boehringer Ingelheim Kg | Useful for treating neurodegenerative diseases |
| DE4121821A1 (de) | 1991-07-02 | 1993-01-14 | Boehringer Ingelheim Kg | Neue benzomorphane und ihre verwendung als arzneimittel |
| US5219347A (en) | 1991-12-24 | 1993-06-15 | Laser Engineering, Inc. | Decoupled dual-beam control system |
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| US6271239B1 (en) | 1992-04-13 | 2001-08-07 | Regents Of The University Of Minnesota | Delta opioid receptor-selective benzylidene-substituted morphinans |
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| US5912347A (en) | 1996-09-30 | 1999-06-15 | Mallinckrodt Inc. | Process for preparing a morphinan derivative |
| US5780479A (en) | 1997-04-04 | 1998-07-14 | Regents Of The University Of Minnesota | Use of opioid antagonists to treat impulse-control disorders |
| JPH1160483A (ja) * | 1997-08-25 | 1999-03-02 | Akira Kanematsu | Tnf産生阻害剤 |
| JPH1160484A (ja) * | 1997-08-25 | 1999-03-02 | Akira Kanematsu | Tnf産生阻害剤 |
| US6166211A (en) * | 1999-03-19 | 2000-12-26 | Endo Pharmaceuticals, Inc. | Sequential benzylic oxidations of the naloxone ring system |
| JP2001058957A (ja) * | 1999-08-20 | 2001-03-06 | Toray Ind Inc | 癌転移抑制剤 |
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| AU2002227135B2 (en) * | 2000-10-31 | 2008-01-03 | Rensselaer Polytechnic Institute | 8- substituted-2, 6-methano-3-benzazocines and 3-substituted morphinanes as opioid receptor binding agents |
| US20030144312A1 (en) * | 2001-10-30 | 2003-07-31 | Schoenhard Grant L. | Inhibitors of ABC drug transporters in multidrug resistant cancer cells |
-
2003
- 2003-05-16 EP EP15186541.7A patent/EP2987788A1/en not_active Withdrawn
- 2003-05-16 AU AU2003234621A patent/AU2003234621A1/en not_active Abandoned
- 2003-05-16 CA CA2486157A patent/CA2486157C/en not_active Expired - Fee Related
- 2003-05-16 MX MXPA04011327A patent/MXPA04011327A/es not_active Application Discontinuation
- 2003-05-16 CN CN201310094981.6A patent/CN103405431B/zh not_active Expired - Lifetime
- 2003-05-16 JP JP2004505341A patent/JP5438250B2/ja not_active Expired - Fee Related
- 2003-05-16 WO PCT/US2003/015461 patent/WO2003097608A2/en not_active Ceased
- 2003-05-16 CN CN038112396A patent/CN1653050B/zh not_active Expired - Lifetime
- 2003-05-16 EP EP03728964.2A patent/EP1506174B1/en not_active Expired - Lifetime
- 2003-11-17 TW TWOPIOIDANA patent/TWI275591B/zh not_active IP Right Cessation
-
2010
- 2010-08-24 AU AU2010212517A patent/AU2010212517A1/en not_active Abandoned
-
2013
- 2013-11-01 JP JP2013228118A patent/JP6165592B2/ja not_active Expired - Fee Related
-
2015
- 2015-04-24 JP JP2015089558A patent/JP6193298B2/ja not_active Expired - Lifetime
-
2016
- 2016-07-18 HK HK16108452.6A patent/HK1220452A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2486157A1 (en) | 2003-11-27 |
| AU2003234621A1 (en) | 2003-12-02 |
| JP2005530798A (ja) | 2005-10-13 |
| EP1506174B1 (en) | 2015-09-30 |
| JP2015155449A (ja) | 2015-08-27 |
| HK1192711A1 (zh) | 2014-08-29 |
| JP5438250B2 (ja) | 2014-03-12 |
| CN1653050A (zh) | 2005-08-10 |
| CN103405431B (zh) | 2016-04-13 |
| CN103405431A (zh) | 2013-11-27 |
| EP2987788A1 (en) | 2016-02-24 |
| JP6165592B2 (ja) | 2017-07-19 |
| JP2014043452A (ja) | 2014-03-13 |
| AU2010212517A1 (en) | 2010-09-16 |
| WO2003097608A2 (en) | 2003-11-27 |
| TW200427690A (en) | 2004-12-16 |
| TWI275591B (en) | 2007-03-11 |
| JP6193298B2 (ja) | 2017-09-06 |
| MXPA04011327A (es) | 2005-08-15 |
| CN1653050B (zh) | 2013-04-24 |
| EP1506174A2 (en) | 2005-02-16 |
| WO2003097608A3 (en) | 2004-03-18 |
| CA2486157C (en) | 2013-04-16 |
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