HK1209100A1 - N-substituted benzamides and their use in the treatment of pain - Google Patents
N-substituted benzamides and their use in the treatment of pain Download PDFInfo
- Publication number
- HK1209100A1 HK1209100A1 HK15109785.3A HK15109785A HK1209100A1 HK 1209100 A1 HK1209100 A1 HK 1209100A1 HK 15109785 A HK15109785 A HK 15109785A HK 1209100 A1 HK1209100 A1 HK 1209100A1
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- pain
- treatment
- substituted benzamides
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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| MX2014005297A (es) | 2011-10-31 | 2014-09-11 | Xenon Pharmaceuticals Inc | Compuestos de bencenosulfonamida y su uso como agentes terapeuticos. |
| US8426450B1 (en) | 2011-11-29 | 2013-04-23 | Helsinn Healthcare Sa | Substituted 4-phenyl pyridines having anti-emetic effect |
| SG11201408284VA (en) | 2012-05-22 | 2015-02-27 | Xenon Pharmaceuticals Inc | N-substituted benzamides and their use in the treatment of pain |
| CN104797555B (zh) | 2012-07-06 | 2017-12-22 | 基因泰克公司 | N‑取代的苯甲酰胺及其使用方法 |
| EP4282419A1 (en) | 2012-12-20 | 2023-11-29 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| US10053463B2 (en) | 2013-03-14 | 2018-08-21 | Janssen Pharmaceutica Nv | Substituted [1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators |
| EP2968280A4 (en) | 2013-03-14 | 2016-08-10 | Genentech Inc | SUBSTITUTED TRIAZOLOPYRIDINES AND METHOD OF USE THEREOF |
| EP3321266A1 (en) | 2013-03-14 | 2018-05-16 | Janssen Pharmaceutica NV | P2x7 modulators |
| ES2845473T3 (es) | 2013-03-14 | 2021-07-26 | Boehringer Ingelheim Int | (Bencil-ciano-metil)-amidas sustituidas de ácido 2-aza-biciclo[2.2.1]heptano-3-carboxílico inhibidores de la catepsina- C |
| JO3773B1 (ar) | 2013-03-14 | 2021-01-31 | Janssen Pharmaceutica Nv | معدلات p2x7 |
| TWI627174B (zh) | 2013-03-14 | 2018-06-21 | 比利時商健生藥品公司 | P2x7調控劑 |
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| EP3450428A1 (en) * | 2013-11-27 | 2019-03-06 | Genentech, Inc. | Substituted benzamides and methods of use thereof |
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| EP3166939B1 (en) | 2014-07-07 | 2019-06-05 | Genentech, Inc. | Therapeutic compounds and methods of use thereof |
| US20180118749A1 (en) | 2014-09-12 | 2018-05-03 | Janssen Pharmaceutica Nv | P2x7 modulators |
| WO2016039977A1 (en) | 2014-09-12 | 2016-03-17 | Janssen Pharmaceutica Nv | P2x7 modulators |
| MX367316B (es) | 2014-09-12 | 2019-08-15 | Boehringer Ingelheim Int | Inhibidores espirociclicos de catepsina c. |
| JP6896619B2 (ja) | 2014-10-06 | 2021-06-30 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | 嚢胞性線維症膜貫通コンダクタンス制御因子のモジュレーター |
| CN107428683B (zh) * | 2015-02-04 | 2020-06-02 | 上海海雁医药科技有限公司 | 杂环取代的n-磺酰基苯甲酰胺衍生物、其制法与医药上的用途 |
| KR102412146B1 (ko) | 2015-02-11 | 2022-06-22 | 주식회사 아이엔테라퓨틱스 | 소디움 채널 차단제 |
| MA42118A (fr) | 2015-05-22 | 2018-03-28 | Genentech Inc | Benzamides substitués et leurs méthodes d'utilisation |
| CN106243003B (zh) * | 2015-06-03 | 2018-03-09 | 上海海雁医药科技有限公司 | 环烃基取代的甲磺酰基苯甲酰胺衍生物、其制法与医药上的用途 |
| JP2018526371A (ja) | 2015-08-27 | 2018-09-13 | ジェネンテック, インコーポレイテッド | 治療化合物及びその使用方法 |
| RU2018115718A (ru) | 2015-09-28 | 2019-10-28 | Дженентек, Инк. | Терапевтические соединения и способы их применения |
| JP6559894B2 (ja) | 2015-11-13 | 2019-08-14 | デウン ファーマシューティカル カンパニー リミテッド | ナトリウムチャネル遮断剤 |
| JP2018535234A (ja) | 2015-11-25 | 2018-11-29 | ジェネンテック, インコーポレイテッド | ナトリウムチャネル遮断薬として有用な置換ベンズアミド |
| SG11201804936UA (en) | 2015-12-18 | 2018-07-30 | Merck Sharp & Dohme | Hydroxyalkylamine- and hydroxycycloalkylamine-substituted diamine-arylsulfonamide compounds with selective activity in voltage-gated sodium channels |
| CA3011169A1 (en) * | 2016-02-03 | 2017-08-10 | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. | N-sulfonyl benzamide derivative with heterocyclic substituent, preparation method therefor and pharmaceutical application thereof |
| CN109071426A (zh) * | 2016-03-30 | 2018-12-21 | 基因泰克公司 | 取代的苯甲酰胺及其使用方法 |
| AU2017240685B2 (en) | 2016-03-31 | 2021-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
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| CA3039853A1 (en) | 2016-10-17 | 2018-04-26 | Genentech, Inc. | Therapeutic compounds and methods of use thereof |
| SG10201912372XA (en) | 2016-12-09 | 2020-02-27 | Xenon Pharmaceuticals Inc | Benzenesulfonamide compounds and their use as therapeutic agents |
| JOP20190125B1 (ar) | 2016-12-09 | 2022-03-14 | Vertex Pharma | مُعدِّل لمنظم موصلية التليف الكيسي عبر الغشاء، وتركيبات صيدلانية، وطرق للعلاج، وعملية لتصنيع المُعدِّل |
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2013
- 2013-05-21 SG SG11201408284VA patent/SG11201408284VA/en unknown
- 2013-05-21 BR BR112014029161A patent/BR112014029161A2/pt not_active IP Right Cessation
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- 2013-05-21 IN IN2574MUN2014 patent/IN2014MN02574A/en unknown
- 2013-05-21 US US13/899,469 patent/US8933236B2/en not_active Expired - Fee Related
- 2013-05-21 MX MX2014014234A patent/MX2014014234A/es unknown
- 2013-05-21 PE PE2014002206A patent/PE20150400A1/es not_active Application Discontinuation
- 2013-05-21 HK HK15109785.3A patent/HK1209100A1/xx unknown
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- 2013-05-21 EP EP13726976.7A patent/EP2855428A1/en not_active Withdrawn
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- 2013-05-21 CA CA2874621A patent/CA2874621A1/en not_active Abandoned
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- 2014-12-02 US US14/558,440 patent/US20150224071A1/en not_active Abandoned
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