HK1203627A1 - Fluidic devices and systems for sample preparation or autonomous analysis - Google Patents

Fluidic devices and systems for sample preparation or autonomous analysis

Info

Publication number
HK1203627A1
HK1203627A1 HK15104227.0A HK15104227A HK1203627A1 HK 1203627 A1 HK1203627 A1 HK 1203627A1 HK 15104227 A HK15104227 A HK 15104227A HK 1203627 A1 HK1203627 A1 HK 1203627A1
Authority
HK
Hong Kong
Prior art keywords
systems
sample preparation
fluidic devices
autonomous analysis
autonomous
Prior art date
Application number
HK15104227.0A
Other languages
English (en)
Chinese (zh)
Inventor
盧斯特曼‧
‧伊斯馬吉洛夫
峰‧沈
亮‧李
宇-祥‧許
斯特凡諾‧貝格洛
米哈伊爾‧卡雷莫夫
大衛‧塞爾克
斯蒂芬妮‧麥卡拉
菲利普‧詹姆斯‧霍姆伍德
Original Assignee
California Inst Of Techn
Slipchip Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Inst Of Techn, Slipchip Corp filed Critical California Inst Of Techn
Publication of HK1203627A1 publication Critical patent/HK1203627A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525Multi-layer analytical elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0605Metering of fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0673Handling of plugs of fluid surrounded by immiscible fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0678Facilitating or initiating evaporation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/045Connecting closures to device or container whereby the whole cover is slidable
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0681Filter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0803Disc shape
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867Multiple inlets and one sample wells, e.g. mixing, dilution
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874Three dimensional network
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/0644Valves, specific forms thereof with moving parts rotary valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/065Valves, specific forms thereof with moving parts sliding valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52Containers specially adapted for storing or dispensing a reagent
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
HK15104227.0A 2012-04-20 2015-05-04 Fluidic devices and systems for sample preparation or autonomous analysis HK1203627A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261636426P 2012-04-20 2012-04-20
US201261726089P 2012-11-14 2012-11-14
PCT/US2013/037660 WO2013159117A1 (en) 2012-04-20 2013-04-22 Fluidic devices and systems for sample preparation or autonomous analysis

Publications (1)

Publication Number Publication Date
HK1203627A1 true HK1203627A1 (en) 2015-10-30

Family

ID=49384155

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15104227.0A HK1203627A1 (en) 2012-04-20 2015-05-04 Fluidic devices and systems for sample preparation or autonomous analysis

Country Status (8)

Country Link
US (1) US9822356B2 (xx)
EP (1) EP2839260B1 (xx)
JP (1) JP6196661B2 (xx)
CN (1) CN104428651B (xx)
AU (2) AU2013249007B2 (xx)
CA (1) CA2870999A1 (xx)
HK (1) HK1203627A1 (xx)
WO (1) WO2013159117A1 (xx)

Families Citing this family (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6057251B2 (ja) * 2011-11-11 2017-01-11 国立研究開発法人産業技術総合研究所 粒子分別装置および粒子分別方法
DE102012100824A1 (de) * 2012-02-01 2013-09-05 Albert-Ludwigs-Universität Freiburg Gemultiplexte Digital PCR
WO2013113072A1 (en) 2012-02-03 2013-08-08 Axxin Pty Ltd Nucleic acid amplification and detection apparatus and method
US20130199775A1 (en) * 2012-02-08 2013-08-08 Baker Hughes Incorporated Monitoring Flow Past Submersible Well Pump Motor with Sail Switch
US11360076B2 (en) 2012-03-30 2022-06-14 Weavr Health Corp. Methods and systems to collect a biological sample
US9808798B2 (en) 2012-04-20 2017-11-07 California Institute Of Technology Fluidic devices for biospecimen preservation
US9822356B2 (en) 2012-04-20 2017-11-21 California Institute Of Technology Fluidic devices and systems for sample preparation or autonomous analysis
US9803237B2 (en) 2012-04-24 2017-10-31 California Institute Of Technology Slip-induced compartmentalization
US9480966B2 (en) 2012-04-30 2016-11-01 General Electric Company Substrates and methods for collection, stabilization and elution of biomolecules
US20160016166A1 (en) * 2013-03-14 2016-01-21 Diagnostics For All, Inc. Molecular diagnostic devices with magnetic components
WO2014169072A2 (en) * 2013-04-11 2014-10-16 Rarecyte, Inc. Kits and methods for separating a target analyte from a suspension
US11358138B2 (en) 2013-07-19 2022-06-14 Boston Microfluidics Inc. Fluid sample collection device
JP2016532075A (ja) * 2013-09-18 2016-10-13 カリフォルニア インスティテュート オブ テクノロジー 移動およびタイミング制御のためのシステムおよび方法
WO2015058008A2 (en) 2013-10-18 2015-04-23 California Institute Of Technology Enhanced nucleic acid identification and detection
GB201318814D0 (en) * 2013-10-24 2013-12-11 Petroleum & Chemical Corp Microfluidic devices and arrangements for supplying such devices with reagents and biological samples
US10252264B2 (en) 2014-02-05 2019-04-09 Talis Biomedical Corporation Sample preparation module with stepwise pressurization mechanism
GB201403522D0 (en) 2014-02-28 2014-04-16 Ge Healthcare Uk Ltd Improvements in and relating to processed biological sample storage
SG11201608021TA (en) * 2014-04-25 2016-11-29 Gen Electric Substrates and methods for collection, stabilization and elution of biomolecules
US9505058B2 (en) * 2014-05-16 2016-11-29 Xerox Corporation Stabilized metallic nanoparticles for 3D printing
US9506908B2 (en) 2014-10-06 2016-11-29 Alveo Technologies, Inc. System for detection of analytes
US9921182B2 (en) 2014-10-06 2018-03-20 ALVEO Technologies Inc. System and method for detection of mercury
US10627358B2 (en) 2014-10-06 2020-04-21 Alveo Technologies, Inc. Method for detection of analytes
US10352899B2 (en) 2014-10-06 2019-07-16 ALVEO Technologies Inc. System and method for detection of silver
US10196678B2 (en) 2014-10-06 2019-02-05 ALVEO Technologies Inc. System and method for detection of nucleic acids
JP7055020B2 (ja) * 2014-11-05 2022-04-15 カリフォルニア インスティテュート オブ テクノロジー 薬剤に対する生物の応答のマイクロ流体測定
ES2809600T3 (es) 2014-11-14 2021-03-04 Axxin Pty Ltd Conjunto de recogida y almacenamiento de muestras biológicas
CN105572233A (zh) * 2014-11-18 2016-05-11 湖南农业大学 植物叶片中琥珀酰丙酮的检测方法
WO2016105508A2 (en) * 2014-12-23 2016-06-30 California Institute Of Technology Devices and methods for autonomous measurements
WO2016170126A1 (en) * 2015-04-22 2016-10-27 Stilla Technologies Contact-less priming method for loading a solution in a microfluidic device and associated system
US10668467B2 (en) * 2015-06-10 2020-06-02 Texas Tech University System Microfluidic device for studying nematodes
EP3325156A4 (en) * 2015-07-17 2019-01-16 Axxin Pty Ltd DIAGNOSTIC TEST ASSEMBLY, APPARATUS, METHOD
KR101982332B1 (ko) 2015-08-10 2019-05-24 에센릭스 코프. 단계 간단화, 소량 샘플, 속도 가속화, 사용이 용이한 생물화학 측정장치 및 방법
ES2963004T3 (es) 2015-09-09 2024-03-22 Drawbridge Health Inc Dispositivos para la recopilación, estabilización y conservación de muestras
IL258100B2 (en) 2015-09-14 2023-04-01 Essenlix Corp Apparatus and system for collecting and analyzing condensed vapor, especially condensed exhalation, and methods for using the same
MY194887A (en) 2015-09-14 2022-12-21 Essenlix Corp Device and System for Analyzing a Sample, Particularly Blood, as Well as Methods of Using The Same
WO2017066645A1 (en) * 2015-10-15 2017-04-20 Inbios International, Inc. Multiplexed lateral flow assay systems and methods for their use
WO2017154349A1 (ja) * 2016-03-10 2017-09-14 パナソニックIpマネジメント株式会社 核酸抽出装置、核酸抽出ユニット及び核酸抽出方法
US10596566B2 (en) * 2016-04-15 2020-03-24 Mauk et al. Capillary-action microfluidic device for point-of-care diagnostics
CN109689887A (zh) * 2016-07-08 2019-04-26 加州理工学院 用于进行低浓度分析物的流动通过捕获的方法和装置
EP3500662B1 (en) 2016-08-20 2022-10-05 The Regents Of The University Of California High-throughput system and method for the temporary permeabilization of cells
WO2018037092A1 (en) 2016-08-26 2018-03-01 Sanofi Multispecific antibodies facilitating selective light chain pairing
CN107785089B (zh) * 2016-08-30 2022-04-19 中国辐射防护研究院 一种利用废分子筛处理放射性废物的方法
US11168347B2 (en) 2016-09-23 2021-11-09 California Institute Of Technology Digital quantification of DNA replication and/or chromosome segregation based determination of antimicrobial susceptibility
JP7146743B2 (ja) 2016-09-23 2022-10-04 アルヴェオ テクノロジーズ インコーポレイテッド 分析種を検出するための方法および組成物
WO2018119318A1 (en) 2016-12-21 2018-06-28 Essenlix Corporation Devices and methods for authenticating a sample and use of the same
US11612888B2 (en) 2017-01-04 2023-03-28 The Research Foundation For The State University Of New York Biomarker detection device
JP7248577B2 (ja) 2017-01-10 2023-03-29 ドローブリッジ ヘルス,インコーポレイテッド サンプル採取のための装置、システム及び方法
WO2018148342A1 (en) 2017-02-07 2018-08-16 Essenlix Corporation Compressed open flow assay and use
US11927560B2 (en) 2017-02-08 2024-03-12 Essenlix Corporation Bio/chemical material extraction and assay
CN111656155B (zh) 2017-02-08 2024-05-31 上海宜晟生物科技有限公司 用于延迟分析的样品采集和操作
US11604148B2 (en) 2017-02-09 2023-03-14 Essenlix Corporation Colorimetric assays
CN111433606B (zh) 2017-02-09 2024-05-24 上海宜晟生物科技有限公司 采用不同间距高度的测定
CN110998325A (zh) 2017-02-09 2020-04-10 Essenlix公司 扩增测定
CA3053301A1 (en) 2017-02-16 2018-08-23 Essenlix Corporation Assay with textured surface
US11685113B2 (en) 2017-03-06 2023-06-27 Katholieke Universiteit Leuven 3D printing of porous liquid handling device
CN106840828B (zh) * 2017-03-29 2020-02-14 天津中新科炬生物制药股份有限公司 一种微量全血中快速分离血浆的方法及分离装置
US11213824B2 (en) 2017-03-29 2022-01-04 The Research Foundation For The State University Of New York Microfluidic device and methods
EP3606668A1 (en) * 2017-04-04 2020-02-12 Selfdiagnostics Deutschland GmbH Lamp component distribution in a microfluid cell
EP3639012A1 (en) * 2017-06-13 2020-04-22 DrinkSavvy, Inc. Colorimetric sensors and methods of manufacturing the same
US11280706B2 (en) 2017-08-01 2022-03-22 Essenlix Corporation Dilution calibration
CN111492222A (zh) 2017-08-01 2020-08-04 Essenlix公司 样品收集、保持和测定
US11725227B2 (en) 2017-08-01 2023-08-15 Essenlix Corporation Devices and methods for examining drug effects on microorganisms
KR102192651B1 (ko) * 2017-08-23 2020-12-17 노을 주식회사 시약을 저장하는 저장 매체 및 이를 이용한 검사 방법 및 검사 모듈
CN107569243B (zh) * 2017-08-30 2021-03-19 天津华鸿科技股份有限公司 一种足跟采血器
CN109490259A (zh) * 2017-09-11 2019-03-19 台达电子国际(新加坡)私人有限公司 多色荧光激发及检测装置及其核酸分析设备应用
US11149265B2 (en) 2017-09-14 2021-10-19 California Institute Of Technology Purification and detection of analytes
US11709175B2 (en) 2017-09-27 2023-07-25 Axxin Pty Ltd Diagnostic test system and method utilizing a closure/sample dispensing mechanism to dispense a sample subvolume for testing
AU2018345841A1 (en) 2017-10-06 2020-05-21 The Research Foundation For The State University For The State Of New York Selective optical aqueous and non-aqueous detection of free sulfites
WO2019075264A1 (en) 2017-10-11 2019-04-18 California Institute Of Technology ANTIBIOSENSITIVITY OF MICROORGANISMS AND COMPOSITIONS, METHODS AND ASSOCIATED SYSTEMS
WO2019075415A1 (en) 2017-10-13 2019-04-18 Essenlix Corporation DEVICES AND METHODS FOR AUTHENTICATING MEDICAL ANALYSIS AND USES THEREOF
US11237113B2 (en) 2017-10-26 2022-02-01 Essenlix Corporation Rapid pH measurement
US10807095B2 (en) 2017-10-26 2020-10-20 Essenlix Corporation Making and tracking assay card
US11609224B2 (en) 2017-10-26 2023-03-21 Essenlix Corporation Devices and methods for white blood cell analyses
CA3080481A1 (en) 2017-10-27 2019-05-02 Boston Microfluidics, Inc. Fluid sample collection device
DE102017125881B4 (de) 2017-11-06 2019-06-19 Sartorius Stedim Biotech Gmbh Filtermodul und Verfahren zum Nachweis von Mirkoorganismen
WO2019118652A1 (en) 2017-12-12 2019-06-20 Essenlix Corporation Sample manipulation and assay with rapid temperature change
CN112534259A (zh) 2017-12-14 2021-03-19 Essenlix公司 监测毛发的装置,系统和方法
AU2018398050B2 (en) * 2017-12-27 2024-03-21 Sekisui Chemical Co., Ltd. Scaffolding material for stem cell cultures and stem cell culture method using same
SG11201903333SA (en) 2017-12-29 2019-08-27 Clear Labs Inc Automated priming and library loading services
WO2019140334A1 (en) 2018-01-11 2019-07-18 Essenlix Corporation Homogeneous assay (ii)
GB201801019D0 (en) 2018-01-22 2018-03-07 Q Linea Ab Sample holder
US20210031187A1 (en) * 2018-02-23 2021-02-04 University Of Virginia Patent Foundation Slipchip device for on-chip dilution and size-based extraction of protein labeling reagents
US10046322B1 (en) 2018-03-22 2018-08-14 Talis Biomedical Corporation Reaction well for assay device
US11498070B2 (en) 2018-03-23 2022-11-15 The Trustees Of The University Of Pennsylvania Microfluidic devices with tunable wettability and solvent resistance and methods for manufacturing the same
CN108855254B (zh) * 2018-04-11 2020-09-11 上海理工大学 一种基于微流控技术的蛋白质浓度检测芯片
US11484877B2 (en) 2018-05-29 2022-11-01 Weavr Health Corp. Blood metering device with desiccant and support for storage media and inlay with flange
US11885952B2 (en) 2018-07-30 2024-01-30 Essenlix Corporation Optics, device, and system for assaying and imaging
EP3837525A4 (en) * 2018-08-16 2023-03-08 Essenlix Corporation IMAGE-BASED ASSAY USING INTELLIGENT MONITORING STRUCTURES
CN109212236B (zh) * 2018-08-31 2021-05-18 深圳市国赛生物技术有限公司 检测糖化血红蛋白浓度的试剂盒
US11772097B2 (en) 2018-10-19 2023-10-03 Renegadexbio, Pbc Simultaneous spot test and storage of blood samples
GB2595060B (en) 2018-10-23 2022-11-02 Weavr Health Corp Funnel with extension tube to augment blood collection device
AU2018101602A4 (en) * 2018-10-25 2018-12-13 We Test Pty Ltd EXPECTORATE DEVICE TEST FOR DEHYDRATION (SPECIFIC GRAVITY) We Test®: Dehydration The users expectorate on a reagent which changes colour dependent upon their hydration levels.
CN113347926A (zh) * 2018-11-28 2021-09-03 维福尔健康公司 血液样本的同时现场测试和储存
KR102182376B1 (ko) * 2019-02-13 2020-11-24 한국기계연구원 현장 진단용 저전력 일체형 분자진단 카트리지
CN110146361B (zh) * 2019-06-18 2022-04-01 安徽理工大学 一种弱胶结贯通裂隙岩石试件柔性打磨装置
US11712177B2 (en) 2019-08-12 2023-08-01 Essenlix Corporation Assay with textured surface
US10820847B1 (en) 2019-08-15 2020-11-03 Talis Biomedical Corporation Diagnostic system
CN110669671B (zh) * 2019-09-04 2022-10-14 杭州师范大学 一种基于中空纤维膜的细胞代谢连续监测装置与方法
JP2021060239A (ja) * 2019-10-04 2021-04-15 国立研究開発法人産業技術総合研究所 濃縮装置
US11919000B2 (en) 2019-10-10 2024-03-05 1859, Inc. Methods and systems for microfluidic screening
EP3822634A1 (en) * 2019-11-14 2021-05-19 Apex Biotechnology Corporation Biosensor strip and method thereof
CN110931344B (zh) * 2019-12-09 2022-06-03 广东省半导体产业技术研究院 一种用于质谱检测的介电型样品靶片及其制作方法
US11130994B2 (en) * 2019-12-13 2021-09-28 Autonomous Medical Devices Inc. Automated, cloud-based, point-of-care (POC) pathogen and antibody array detection system and method
US11866695B2 (en) 2019-12-23 2024-01-09 California Institute Of Technology Methods and systems and related compositions for mixtures separation with a solid matrix
CN111238890B (zh) * 2020-01-16 2024-03-19 南昌准好生物科技有限公司 基于离心法的液基制片技术用于液基真菌的检测方法
US20230050667A1 (en) * 2020-01-29 2023-02-16 Nippon Telegraph And Telephone Corporation Concentration Device
WO2021206752A1 (en) * 2020-04-08 2021-10-14 Indiana Biosciences Research Institute, Inc. System and method for sensing, capture and release of biomolecules or cells
JP7409944B2 (ja) 2020-04-10 2024-01-09 国立大学法人 東京大学 細胞内構成物質の抽出方法
WO2022031992A1 (en) * 2020-08-05 2022-02-10 Rely Biotech Inc. Lysis buffer compositions and methods for preparing a viral biological sample useful for covid-19 testing
US11498069B2 (en) * 2020-08-31 2022-11-15 International Business Machines Corporation Rapid testing device for wastewater analysis
TR202022438A2 (tr) * 2020-12-30 2022-07-21 Argeron Medikal Arastirma Sanayi Ve Ticaret Anonim Sirketi İdrarda Trehalaz Ölçümüne Yönelik Bir Solüsyon ve Bu Solüsyonun Kullanıldığı Ölçüm Yöntemi
WO2022155246A1 (en) * 2021-01-12 2022-07-21 Definitive Biotechnologies Llc Device and method for detecting nucleic acids in biological samples
CN112964775B (zh) * 2021-02-01 2022-05-31 中国地质大学(武汉) 一种应用于la-icp-ms分析的目标靶的制作方法
CN114011478B (zh) * 2021-02-20 2023-06-02 中国海洋石油集团有限公司 一种多功能微流控芯片及其制作方法
US11857965B2 (en) 2021-08-25 2024-01-02 Hewlett-Packard Development Company, L.P. Microfluidic valves
WO2023048701A1 (en) * 2021-09-22 2023-03-30 Hewlett-Packard Development Company, L.P. Microfluidic droplet controls
GB2611355A (en) * 2021-10-04 2023-04-05 52 North Health Ltd Assay device for a suspension
WO2023167995A2 (en) * 2022-03-03 2023-09-07 Trustees Of Tufts College Articles and methods for cell transport
WO2023177528A1 (en) * 2022-03-15 2023-09-21 The Board Of Trustees Of The University Of Illinois Microfluidic system and method
CN115283026A (zh) * 2022-07-06 2022-11-04 上海交通大学 集成式滑动芯片
CN115201276B (zh) * 2022-09-09 2023-01-06 深圳市勘察研究院有限公司 一种污水排放检测设备
CN115541861B (zh) * 2022-12-05 2023-03-10 山东第一医科大学附属省立医院(山东省立医院) 一种神经内科体液取样检测装置
CN115926980B (zh) * 2022-12-23 2023-10-24 成都诺医德医学检验实验室有限公司 一种用于细胞培养的芯片装置及方法
CN116606727B (zh) * 2023-04-17 2024-03-12 长庚大学 核酸检测装置及核酸检测方法

Family Cites Families (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US344922A (en) 1886-07-06 Mechanical clock
US1489762A (en) 1921-10-29 1924-04-08 Hudd Alfred Ernest Time-element device
US1926276A (en) 1927-12-14 1933-09-12 Waters Genter Company Timing mechanism
US2541413A (en) 1947-04-01 1951-02-13 Graflex Inc Photographic camera and shutter therefor
US2895547A (en) 1950-10-11 1959-07-21 Dormeyer Corp Food mixer timer
US4036006A (en) 1974-02-06 1977-07-19 Gunther Glaser Time-keeping apparatus
US4001527A (en) 1974-06-03 1977-01-04 Stephen Joseph Hulshizer Electrical timer-switch
US4021626A (en) 1975-07-25 1977-05-03 Becker Robert R Mechanical light switch timer
US4912376A (en) 1988-05-11 1990-03-27 Strick Robert E Timed actuator for conventional wall switch
US5160853A (en) 1988-08-08 1992-11-03 Honeywell Inc. Electronic timer switch with time tracker
US5026113A (en) 1988-09-09 1991-06-25 Sky-Top Sunroofs Ltd. Sliding and venting sunroof
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5114208A (en) 1989-08-04 1992-05-19 Aisin Seiki Kabushiki Kaisha Sliding mechanism for sunroof
US5256571A (en) 1991-05-01 1993-10-26 Cytyc Corporation Cell preservative solution
US5582988A (en) 1994-09-15 1996-12-10 Johnson & Johnson Clinical Diagnostics, Inc. Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same
US5688651A (en) 1994-12-16 1997-11-18 Ramot University Authority For Applied Research And Development Ltd. Prevention of protein aggregation
US5590687A (en) 1995-06-07 1997-01-07 Fleck Controls, Inc. Control mechanism for a water conditioning system
US5805947A (en) 1995-12-08 1998-09-08 Nikon Corporation Camera provided with a sliding cover
GB9625622D0 (en) 1996-12-10 1997-01-29 Expo Safety Syst Fluid operated timer
US6300138B1 (en) 1997-08-01 2001-10-09 Qualigen, Inc. Methods for conducting tests
US6426230B1 (en) 1997-08-01 2002-07-30 Qualigen, Inc. Disposable diagnostic device and method
US5919711A (en) * 1997-08-07 1999-07-06 Careside, Inc. Analytical cartridge
US5926660A (en) 1997-09-30 1999-07-20 Eastman Kodak Company Camera and mechanical timer mechanism
US6120733A (en) * 1997-11-12 2000-09-19 Goodman; David B. P. Self-contained assay device
US6914137B2 (en) 1997-12-06 2005-07-05 Dna Research Innovations Limited Isolation of nucleic acids
DE69805649T2 (de) 1997-12-06 2002-12-05 Dna Res Innovations Ltd Isolierung von nukleinsäuren
US6761816B1 (en) 1998-06-23 2004-07-13 Clinical Micro Systems, Inc. Printed circuit boards with monolayers and capture ligands
US6204375B1 (en) 1998-07-31 2001-03-20 Ambion, Inc. Methods and reagents for preserving RNA in cell and tissue samples
US7914994B2 (en) 1998-12-24 2011-03-29 Cepheid Method for separating an analyte from a sample
WO2000052446A1 (en) 1999-03-02 2000-09-08 Qualigen, Inc. Methods and apparatus for separation of biological fluids
US6299842B1 (en) 1999-03-05 2001-10-09 Meridian Bioscience, Inc. Biological sampling and storage container utilizing a desiccant
ES2308865T3 (es) 1999-03-11 2008-12-01 Whatman, Inc. Medio solido y procedimiento para el almacenamiento y la rapida purificacion de acido nucleico.
GB9915398D0 (en) 1999-07-02 1999-09-01 Baker Matthew J Magnetic particles
US6354172B1 (en) 2000-01-31 2002-03-12 Aquion Partners Limited Partnership Mechanical timer mechanism for valve control
US6949575B2 (en) 2000-05-04 2005-09-27 Pfizer Inc. Method of inhibiting amyloid protein aggregation and imaging amyloid deposits using aminoindane derivatives
GB0011443D0 (en) 2000-05-13 2000-06-28 Dna Research Instr Limited Separation device
JP2003533682A (ja) 2000-05-15 2003-11-11 テカン・トレーディング・アクチェンゲゼルシャフト 双方向流動遠心ミクロ流体装置
US6325172B1 (en) 2000-05-25 2001-12-04 Pvt-Wrl, Llc Geophone including laser interferometer
AU2002310497A1 (en) 2001-06-20 2003-01-08 Caprion Pharmaceuticals Inc. Protein aggregation assays and uses thereof
US20030003962A1 (en) 2001-06-29 2003-01-02 Tan Vooi-Kia Automatic sliding machanism for portable electronic product, particularly for a sliding front cover of a mobile phone
GB0127809D0 (en) 2001-11-20 2002-01-09 Dna Res Innovations Ltd Purification of nucleic acid
US7691333B2 (en) 2001-11-30 2010-04-06 Fluidigm Corporation Microfluidic device and methods of using same
GB0129816D0 (en) 2001-12-13 2002-01-30 The Technology Partnership Plc Testing device for chemical or biochemical analysis
CA2642653A1 (en) * 2002-04-16 2003-10-30 Gambro Bct, Inc. Blood component processing system, apparatus and method
US7901939B2 (en) 2002-05-09 2011-03-08 University Of Chicago Method for performing crystallization and reactions in pressure-driven fluid plugs
EP2278337B1 (en) 2002-05-09 2019-06-26 The University of Chicago Device and method for pressure-driven plug transport and reaction
GB0212825D0 (en) 2002-05-31 2002-07-10 Dna Res Innovations Ltd Methods compositions and kits for cell separation
GB0212826D0 (en) 2002-05-31 2002-07-10 Dna Res Innovations Ltd Materials and methods relating to polyions and substance delivery
JP2004018409A (ja) * 2002-06-13 2004-01-22 Teijin Chem Ltd ペンタエリスリトールジホスファイトの製造方法
JP2006507921A (ja) 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 流体分散のための方法および装置
WO2004012862A2 (en) * 2002-08-02 2004-02-12 Amersham Biosciences (Sv) Corp Integrated microchip design
GB0229287D0 (en) 2002-12-16 2003-01-22 Dna Res Innovations Ltd Polyfunctional reagents
AU2003303594A1 (en) 2002-12-30 2004-07-29 The Regents Of The University Of California Methods and apparatus for pathogen detection and analysis
US6861601B2 (en) 2003-02-27 2005-03-01 Troy A. Heien Mechanical delay timer
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
FI118669B (fi) 2003-04-01 2008-01-31 Samsung Electro Mech Liukutyyppinen matkapuhelin ja liukumismenetelmä siihen
CA2521862C (en) 2003-04-10 2012-10-16 President And Fellows Of Harvard College Formation and control of fluidic species
US20050042770A1 (en) 2003-05-23 2005-02-24 Gyros Ab Fluidic functions based on non-wettable surfaces
AU2004258218B2 (en) 2003-07-18 2009-05-21 Bio-Rad Laboratories, Inc. System and method for multi-analyte detection
GB0317044D0 (en) 2003-07-21 2003-08-27 Dna Res Innovations Ltd Nucleic acid isolation
EP2662136A3 (en) 2003-08-27 2013-12-25 President and Fellows of Harvard College Method for handling and mixing droplets
US7722817B2 (en) 2003-08-28 2010-05-25 Epocal Inc. Lateral flow diagnostic devices with instrument controlled fluidics
BRPI0414067A (pt) * 2003-09-03 2006-10-24 Life Patch International Inc dispositivo pessoal de diagnóstico e método de usar o mesmo
US7003104B2 (en) 2003-10-13 2006-02-21 Hanbit Precision Co., Ltd. Apparatus for opening and closing cover of cellular phone
US7629165B2 (en) 2004-01-22 2009-12-08 Qualigen, Inc Diagnostic device and method
US8158728B2 (en) * 2004-02-13 2012-04-17 The University Of North Carolina At Chapel Hill Methods and materials for fabricating microfluidic devices
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US20060099567A1 (en) 2004-04-08 2006-05-11 Biomatrica, Inc. Integration of sample storage and sample management for life science
EP3167961A1 (en) 2004-04-08 2017-05-17 Biomatrica, Inc. Integration of sample storage and sample management for life science
US20080176209A1 (en) 2004-04-08 2008-07-24 Biomatrica, Inc. Integration of sample storage and sample management for life science
US20060024712A1 (en) 2004-06-25 2006-02-02 Invitrogen Corporation Separation of nucleic acid
US7655470B2 (en) 2004-10-29 2010-02-02 University Of Chicago Method for manipulating a plurality of plugs and performing reactions therein in microfluidic systems
US9477233B2 (en) 2004-07-02 2016-10-25 The University Of Chicago Microfluidic system with a plurality of sequential T-junctions for performing reactions in microdroplets
JP4509182B2 (ja) 2004-07-08 2010-07-21 ハイテック パーツ カンパニー リミテッド スライド型携帯電話用のスライダー組立体及びスライド型携帯電話
US7869844B2 (en) 2004-09-15 2011-01-11 Laird Technologies, Inc. Sliding mechanism for opening and closing of cellular phone
US7579565B2 (en) 2004-09-16 2009-08-25 Shafi Al Dosari Mechanical timer switch assembly
DE202004015484U1 (de) * 2004-10-04 2005-03-17 Pfaff Aqs Gmbh Probenbearbeitungsvorrichtung und Probenanalysevorrichtung
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
US7251142B2 (en) 2004-12-15 2007-07-31 Advanced Timer Technologies Limited Timer switch
US9039273B2 (en) 2005-03-04 2015-05-26 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
US7964413B2 (en) 2005-03-10 2011-06-21 Gen-Probe Incorporated Method for continuous mode processing of multiple reaction receptacles in a real-time amplification assay
JP2008538077A (ja) * 2005-03-16 2008-10-09 ユニバーシティ オブ シカゴ マイクロフルイディックシステム
US7352655B2 (en) 2005-05-17 2008-04-01 Delphi Technologies, Inc. Method and apparatus for automatic time correction of a mechanical clock
US7556776B2 (en) 2005-09-08 2009-07-07 President And Fellows Of Harvard College Microfluidic manipulation of fluids and reactions
US7329485B2 (en) 2005-10-12 2008-02-12 The Board Of Regents Of The University Of Oklahoma Methods for detecting compounds that interfere with protein aggregation utilizing an in vitro fluorescence-based assay
US20090221096A1 (en) 2005-12-13 2009-09-03 Great Basin Scientific Thin film biosensor and method and device for detection of analytes
EP1984738A2 (en) 2006-01-11 2008-10-29 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
ATE484335T1 (de) 2006-01-27 2010-10-15 Harvard College Koaleszenz fluider tröpfchen
US20090104637A1 (en) 2006-01-31 2009-04-23 Ismagilov Rustem F Method and Apparatus for Assaying Blood Clotting
EP2530167A1 (en) 2006-05-11 2012-12-05 Raindance Technologies, Inc. Microfluidic Devices
CA2689548A1 (en) 2006-06-12 2007-12-21 Great Basin Scientific Methods and materials for detecting frameshift mutations
WO2008002267A1 (en) 2006-06-28 2008-01-03 Rgb Technologies Ab A sensor kit and a system for detecting an analyte in a test environment
US7375190B2 (en) 2006-09-19 2008-05-20 National Yang-Ming University Recombinant protein and method of screening for agents that modulate polypeptide aggregation
WO2008057781A2 (en) 2006-10-27 2008-05-15 Montecito Bio-Sciences, Ltd. Portable apparatus for improved sample analysis
WO2008069884A2 (en) 2006-12-01 2008-06-12 Panomics, Inc. Two-stage nucleic acid amplification using an amplification oligomer
WO2008079274A1 (en) 2006-12-19 2008-07-03 University Of Chicago Spacers for microfludic channels
US8338166B2 (en) 2007-01-04 2012-12-25 Lawrence Livermore National Security, Llc Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
KR20100015889A (ko) 2007-04-24 2010-02-12 바이오매트리카 인코포레이티드 생명과학을 위한 시료 저장
EP1998236B1 (fr) 2007-05-30 2010-07-28 Omega SA Echappement à ancre pour pièce d'horlogerie
EP2175999B1 (en) 2007-06-21 2017-01-04 Gen-Probe Incorporated Receptacles for use in performing processes
WO2009048673A2 (en) 2007-07-26 2009-04-16 University Of Chicago Stochastic confinement to detect, manipulate, and utilize molecules and organisms
KR100912530B1 (ko) * 2007-11-13 2009-08-18 한국전자통신연구원 일회용 다층형 혈장 분리 필터 소자
WO2009070742A2 (en) 2007-11-28 2009-06-04 Great Basin Scientific Methods and compositions for signal enhancement using multivalent interactions
US20090215050A1 (en) 2008-02-22 2009-08-27 Robert Delmar Jenison Systems and methods for point-of-care amplification and detection of polynucleotides
US8622987B2 (en) 2008-06-04 2014-01-07 The University Of Chicago Chemistrode, a plug-based microfluidic device and method for stimulation and sampling with high temporal, spatial, and chemical resolution
US8314517B2 (en) 2008-07-29 2012-11-20 Honeywell International Inc. Electric timer for controlling power to a load
WO2010078420A2 (en) 2008-12-30 2010-07-08 Redhorse Fluidics Systems, devices, methods and kits for fluid handling
US9447461B2 (en) 2009-03-24 2016-09-20 California Institute Of Technology Analysis devices, kits, and related methods for digital quantification of nucleic acids and other analytes
KR101796906B1 (ko) * 2009-03-24 2017-11-10 유니버시티 오브 시카고 반응을 수행하기 위한 방법
US9464319B2 (en) 2009-03-24 2016-10-11 California Institute Of Technology Multivolume devices, kits and related methods for quantification of nucleic acids and other analytes
US8263883B2 (en) 2009-04-20 2012-09-11 Heien Troy A Mechanical delay timer
US8519125B2 (en) 2009-05-11 2013-08-27 Biomatrica, Inc. Compositions and methods for biological sample storage
US20110165037A1 (en) 2010-01-07 2011-07-07 Ismagilov Rustem F Interfaces that eliminate non-specific adsorption, and introduce specific interactions
KR101680185B1 (ko) 2010-01-15 2016-11-28 삼성전자주식회사 시료분석용 분석장치
US9458489B2 (en) 2010-03-04 2016-10-04 Massachusetts Institute Of Technology Microfluidics sorter for cell detection and isolation
EP2598660B1 (en) 2010-07-26 2017-03-15 Biomatrica, INC. Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
US9233369B2 (en) 2010-12-23 2016-01-12 California Institute Of Technology Fluidic devices and fabrication methods for microfluidics
US8968585B2 (en) 2010-12-23 2015-03-03 California Institute Of Technology Methods of fabrication of cartridges for biological analysis
US9090890B2 (en) 2011-12-23 2015-07-28 California Institute Of Technology Devices and methods for biological sample preparation
US9518291B2 (en) 2011-12-23 2016-12-13 California Institute Of Technology Devices and methods for biological sample-to-answer and analysis
US8883088B2 (en) 2011-12-23 2014-11-11 California Institute Of Technology Sample preparation devices and systems
US9090891B2 (en) 2011-12-23 2015-07-28 California Institute Of Technology Pen-shaped device for biological sample preparation and analysis
EP2814975A4 (en) 2012-02-14 2015-12-30 Great Basin Scient ISOTHERMAL AMPLIFICATION METHODS USING BLOCKED PRIMERS
US9822356B2 (en) 2012-04-20 2017-11-21 California Institute Of Technology Fluidic devices and systems for sample preparation or autonomous analysis
US9808798B2 (en) 2012-04-20 2017-11-07 California Institute Of Technology Fluidic devices for biospecimen preservation
US9803237B2 (en) 2012-04-24 2017-10-31 California Institute Of Technology Slip-induced compartmentalization
US20130331298A1 (en) 2012-06-06 2013-12-12 Great Basin Scientific Analyzer and disposable cartridge for molecular in vitro diagnostics

Also Published As

Publication number Publication date
JP6196661B2 (ja) 2017-09-13
US20130309679A1 (en) 2013-11-21
CN104428651B (zh) 2019-01-11
EP2839260A4 (en) 2015-10-21
AU2016204953B2 (en) 2017-11-23
AU2016204953A1 (en) 2016-08-04
AU2013249007A1 (en) 2014-11-27
AU2013249007B2 (en) 2016-04-21
CA2870999A1 (en) 2013-10-24
JP2015514997A (ja) 2015-05-21
EP2839260A1 (en) 2015-02-25
EP2839260B1 (en) 2018-07-18
US9822356B2 (en) 2017-11-21
WO2013159117A1 (en) 2013-10-24
CN104428651A (zh) 2015-03-18

Similar Documents

Publication Publication Date Title
HK1203627A1 (en) Fluidic devices and systems for sample preparation or autonomous analysis
IL283216B (en) Microfluidic devices for testing biological activity
IL257714B (en) Systems and methods for the analysis of multiple analytes
HK1211990A1 (en) Methods and systems for microfluidics imaging and analysis
EP2971141A4 (en) SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS
EP3080300A4 (en) Systems and methods for biological analysis and computation
GB201616219D0 (en) Methods and systems for detecting biological components
SG11201405785WA (en) Systems and methods for biological analysis
EP2981349A4 (en) SYSTEMS AND METHODS FOR HANDLING MICROFLUIDIC DROPLETS
HK1209184A1 (en) Methods and systems for measuring and using the oxidation-reduction potential of a biological sample
EP2856120A4 (en) SYSTEM AND METHOD FOR THE ANALYSIS OF BIOLOGICAL LIQUIDS
EP3117221A4 (en) Microfluidic devices, systems and methods for sample preparation and analysis
HK1212285A1 (en) Systems and devices for sample handling
EP3027775A4 (en) Dna sequencing and epigenome analysis
EP2758786A4 (en) SYSTEMS AND METHOD FOR PROVIDING MICROFLUIDIC DEVICES
GB201317085D0 (en) Distributed sample analysis
EP2812676A4 (en) METHODS AND SYSTEMS FOR SAMPLE ANALYSIS
PL2633913T3 (pl) Urządzenie do pipetowania i wielokanałowe urządzenie do pipetowania
SG11201506481QA (en) Optical systems and methods for biological analysis
EP2986386C0 (en) DEVICE FOR SEPARATING A BIOLOGICAL LIQUID AND SYSTEM FOR SEPARATING AND EXAMINING A BIOLOGICAL LIQUID
HK1217990A1 (zh) 用於樣品分析的方法、裝置和系統
EP2986380C0 (en) SYSTEM FOR SAMPLING BIOLOGICAL LIQUIDS AND FOR SEPARATING AND TESTING BIOLOGICAL LIQUIDS
EP2912267A4 (en) SYSTEMS AND METHOD FOR DETECTING ONE OR MORE MEASUREMENTS AND / OR SAMPLES
EP2880420A4 (en) OPTICAL PROCESS FOR CHEMICAL AND BIOCHEMICAL ANALYSIS
GB201310214D0 (en) Separation and Analysis Systems and Methods

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230420