HK1131612A1 - Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases - Google Patents

Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases

Info

Publication number
HK1131612A1
HK1131612A1 HK09110497.8A HK09110497A HK1131612A1 HK 1131612 A1 HK1131612 A1 HK 1131612A1 HK 09110497 A HK09110497 A HK 09110497A HK 1131612 A1 HK1131612 A1 HK 1131612A1
Authority
HK
Hong Kong
Prior art keywords
hydrolases
compounds
nucleoside phosphorylases
acyclic amine
amine inhibitors
Prior art date
Application number
HK09110497.8A
Other languages
English (en)
Inventor
Keith Clinch
Gary Brian Evans
Richard Hubert Furneaux
Peter Michael Kelly
Vern L Schramm
Peter Charles Tyler
Anthony David Woolhouse
Shivali Ashwin Gulab
Original Assignee
Ind Res Ltd
Einstein Coll Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ind Res Ltd, Einstein Coll Med filed Critical Ind Res Ltd
Publication of HK1131612A1 publication Critical patent/HK1131612A1/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
HK09110497.8A 2006-09-07 2009-11-10 Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases HK1131612A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84286706P 2006-09-07 2006-09-07
PCT/NZ2007/000261 WO2008030119A1 (en) 2006-09-07 2007-09-07 Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases

Publications (1)

Publication Number Publication Date
HK1131612A1 true HK1131612A1 (en) 2010-01-29

Family

ID=39157466

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09110497.8A HK1131612A1 (en) 2006-09-07 2009-11-10 Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases

Country Status (20)

Country Link
US (1) US8853224B2 (es)
EP (2) EP2395005A1 (es)
JP (1) JP5388067B2 (es)
KR (1) KR101433621B1 (es)
CN (1) CN101528749B (es)
AT (1) ATE502038T1 (es)
AU (1) AU2007293774C1 (es)
CA (1) CA2662628C (es)
CY (1) CY1111507T1 (es)
DE (1) DE602007013252D1 (es)
DK (1) DK2057165T3 (es)
ES (1) ES2362805T3 (es)
HK (1) HK1131612A1 (es)
HR (1) HRP20110408T1 (es)
NZ (1) NZ575365A (es)
PL (1) PL2057165T3 (es)
PT (1) PT2057165E (es)
RS (1) RS51864B (es)
SI (1) SI2057165T1 (es)
WO (1) WO2008030119A1 (es)

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Also Published As

Publication number Publication date
KR20090069281A (ko) 2009-06-30
DE602007013252D1 (de) 2011-04-28
SI2057165T1 (sl) 2011-07-29
AU2007293774C1 (en) 2014-12-18
WO2008030119A1 (en) 2008-03-13
US20110130412A1 (en) 2011-06-02
EP2057165B1 (en) 2011-03-16
CA2662628C (en) 2016-02-09
JP2010502696A (ja) 2010-01-28
KR101433621B1 (ko) 2014-08-27
HRP20110408T1 (hr) 2011-06-30
EP2057165A4 (en) 2009-09-02
CY1111507T1 (el) 2015-08-05
EP2057165A1 (en) 2009-05-13
PL2057165T3 (pl) 2011-08-31
WO2008030119A9 (en) 2009-09-24
ES2362805T3 (es) 2011-07-13
AU2007293774B2 (en) 2013-07-04
JP5388067B2 (ja) 2014-01-15
CN101528749A (zh) 2009-09-09
RS51864B (en) 2012-02-29
US8853224B2 (en) 2014-10-07
PT2057165E (pt) 2011-05-12
AU2007293774A1 (en) 2008-03-13
CA2662628A1 (en) 2008-03-13
NZ575365A (en) 2012-02-24
EP2395005A1 (en) 2011-12-14
CN101528749B (zh) 2013-07-31
DK2057165T3 (da) 2011-06-27
ATE502038T1 (de) 2011-04-15

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