HK1131344A1 - Transmucosal delivery devices with enhanced uptake - Google Patents
Transmucosal delivery devices with enhanced uptakeInfo
- Publication number
- HK1131344A1 HK1131344A1 HK09110161.3A HK09110161A HK1131344A1 HK 1131344 A1 HK1131344 A1 HK 1131344A1 HK 09110161 A HK09110161 A HK 09110161A HK 1131344 A1 HK1131344 A1 HK 1131344A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- delivery devices
- transmucosal delivery
- enhanced uptake
- uptake
- enhanced
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Zoology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Sheets, Magazines, And Separation Thereof (AREA)
- Friction Gearing (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83272506P | 2006-07-21 | 2006-07-21 | |
US83272606P | 2006-07-21 | 2006-07-21 | |
US83950406P | 2006-08-23 | 2006-08-23 | |
PCT/US2007/016634 WO2008011194A2 (en) | 2006-07-21 | 2007-07-23 | Transmucosal delivery devices with enhanced uptake |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1131344A1 true HK1131344A1 (en) | 2010-01-22 |
Family
ID=38819378
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK09110161.3A HK1131344A1 (en) | 2006-07-21 | 2009-10-30 | Transmucosal delivery devices with enhanced uptake |
HK14106983.0A HK1193566A1 (zh) | 2006-07-21 | 2014-07-09 | 吸收增強的經粘膜遞送裝置 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK14106983.0A HK1193566A1 (zh) | 2006-07-21 | 2014-07-09 | 吸收增強的經粘膜遞送裝置 |
Country Status (23)
Country | Link |
---|---|
US (13) | US20100015183A1 (pl) |
EP (3) | EP3067044B1 (pl) |
JP (2) | JP5448814B2 (pl) |
KR (2) | KR101230804B1 (pl) |
CN (2) | CN103550136B (pl) |
AU (1) | AU2007275581B2 (pl) |
BR (2) | BRPI0714712B8 (pl) |
CA (1) | CA2658585C (pl) |
DK (1) | DK2054031T3 (pl) |
ES (1) | ES2577390T3 (pl) |
HK (2) | HK1131344A1 (pl) |
HR (1) | HRP20160405T1 (pl) |
HU (1) | HUE027395T2 (pl) |
IL (2) | IL196529A (pl) |
MX (1) | MX2009000745A (pl) |
NO (3) | NO340668B1 (pl) |
NZ (2) | NZ574361A (pl) |
PL (1) | PL2054031T3 (pl) |
RS (1) | RS54764B1 (pl) |
RU (3) | RU2504377C2 (pl) |
SI (1) | SI2054031T1 (pl) |
WO (1) | WO2008011194A2 (pl) |
ZA (1) | ZA200900485B (pl) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
US7666337B2 (en) | 2002-04-11 | 2010-02-23 | Monosol Rx, Llc | Polyethylene oxide-based films and drug delivery systems made therefrom |
US8900497B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for making a film having a substantially uniform distribution of components |
US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
US7425292B2 (en) | 2001-10-12 | 2008-09-16 | Monosol Rx, Llc | Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom |
US20070281003A1 (en) | 2001-10-12 | 2007-12-06 | Fuisz Richard C | Polymer-Based Films and Drug Delivery Systems Made Therefrom |
US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US8663687B2 (en) | 2001-10-12 | 2014-03-04 | Monosol Rx, Llc | Film compositions for delivery of actives |
US8900498B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for manufacturing a resulting multi-layer pharmaceutical film |
US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
US8017150B2 (en) | 2002-04-11 | 2011-09-13 | Monosol Rx, Llc | Polyethylene oxide-based films and drug delivery systems made therefrom |
US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
HUE027395T2 (hu) | 2006-07-21 | 2016-10-28 | Biodelivery Sciences Int Inc | Eszközök nyálkahártyán keresztül történõ bejuttatására, javított felszívódással |
EP2063864A4 (en) | 2006-09-20 | 2012-03-14 | Monosol Rx Llc | EDIBLE WATER-SOLUBLE FILM CONTAINING FLAVOR-REDUCING AGENT |
US8298583B2 (en) | 2007-10-19 | 2012-10-30 | Monosol Rx, Llc | Film delivery system for tetrahydrolipstatin |
US20110189259A1 (en) * | 2008-06-23 | 2011-08-04 | Biodelivery Sciences International, Inc. | Multidirectional mucosal delivery devices and methods of use |
US8282954B2 (en) | 2008-12-15 | 2012-10-09 | Monosol Rx, Llc | Method for manufacturing edible film |
AU2010259971C1 (en) | 2009-06-12 | 2017-02-16 | Sunovion Pharmaceuticals Inc. | Sublingual apomorphine |
US8475832B2 (en) | 2009-08-07 | 2013-07-02 | Rb Pharmaceuticals Limited | Sublingual and buccal film compositions |
WO2011156711A1 (en) | 2010-06-10 | 2011-12-15 | Schobel Alexander M | Nanoparticle film delivery systems |
US9149959B2 (en) | 2010-10-22 | 2015-10-06 | Monosol Rx, Llc | Manufacturing of small film strips |
CN103476372B (zh) | 2010-12-16 | 2016-04-27 | Cynapsus疗法有限公司 | 舌下薄膜 |
WO2012104834A1 (en) * | 2011-02-03 | 2012-08-09 | Pharmedica Ltd. | New oral dissolving films for insulin administration, for treating diabetes |
CA2841785A1 (en) | 2011-07-06 | 2013-01-10 | The Parkinson's Institute | Compositions and methods for treatment of symptoms in parkinson's disease patients |
MX352959B (es) * | 2011-08-18 | 2017-12-15 | Biodelivery Sciences Int Inc | Dispositivos mucoadhesivos resistentes al abuso para el suministro de buprenorfina. |
ME02153B (me) | 2011-09-19 | 2015-10-20 | Orexo Ab | Nove farmaceutske kompozicije, otporne na zloupotrebu, za tretman zavisnosti od opioida |
SG11201403075XA (en) * | 2011-12-21 | 2014-07-30 | Biodelivery Sciences Int Inc | Transmucosal drug delivery devices for use in chronic pain relief |
US9901539B2 (en) * | 2011-12-21 | 2018-02-27 | Biodelivery Sciences International, Inc. | Transmucosal drug delivery devices for use in chronic pain relief |
TWI522101B (zh) | 2012-04-17 | 2016-02-21 | 普渡製藥有限合夥事業 | 處理由類鴉片引起之不利的藥效動力反應之系統和方法 |
RS57951B1 (sr) | 2012-05-02 | 2019-01-31 | Orexo Ab | Nova kompozicija alfentanila za tretman akutnog bola |
US9993582B2 (en) | 2012-09-12 | 2018-06-12 | Boston Scientific Scimed, Inc. | Adhesive stent coating for anti-migration |
CN109303628B (zh) | 2013-08-08 | 2021-08-10 | 波士顿科学国际有限公司 | 防止支架移位的可溶性或可降解粘合剂聚合物 |
US9918981B2 (en) | 2013-09-10 | 2018-03-20 | Insys Development Company, Inc. | Liquid buprenorphine formulations |
EP3043777B1 (en) | 2013-09-10 | 2020-04-22 | Fresh Cut Development, LLC | Sublingual buprenorphine spray |
US9839611B2 (en) | 2013-09-10 | 2017-12-12 | Insys Development Company, Inc. | Sublingual buprenorphine spray |
US9867818B2 (en) | 2013-09-10 | 2018-01-16 | Insys Development Company, Inc. | Sublingual buprenorphine spray |
US10722510B2 (en) | 2014-07-08 | 2020-07-28 | Hikma Pharmaceuticals Usa Inc. | Liquid naloxone spray |
US10617686B2 (en) | 2014-07-08 | 2020-04-14 | Hikma Pharmaceuticals Usa Inc. | Liquid naloxone spray |
JP2017519803A (ja) | 2014-07-08 | 2017-07-20 | インシス・ファーマ・インコーポレーテッド | 舌下ナロキソンスプレー |
US20160144528A1 (en) * | 2014-11-25 | 2016-05-26 | Biodelivery Sciences International, Inc. | Patch devices, methods and apparatus for forming, and testing pharmaceutical agent delivery patch devices |
WO2016123406A1 (en) | 2015-01-28 | 2016-08-04 | Chrono Therapeutics Inc. | Drug delivery methods and systems |
US10679516B2 (en) | 2015-03-12 | 2020-06-09 | Morningside Venture Investments Limited | Craving input and support system |
EP3285771A4 (en) | 2015-04-21 | 2018-12-05 | Sunovion Pharmaceuticals Inc. | Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa |
CA2998147A1 (en) * | 2015-09-09 | 2017-03-16 | Biodelivery Sciences International, Inc. | Methods of safely transitioning a subject to buprenorphine |
CA3044944C (en) * | 2015-11-25 | 2021-06-22 | Tbm Company | Film for oral hemostasis and wound protection |
JP2019519487A (ja) | 2016-05-05 | 2019-07-11 | アクエスティブ セラピューティクス インコーポレイテッド | 送達増強エピネフリン組成物 |
US11273131B2 (en) | 2016-05-05 | 2022-03-15 | Aquestive Therapeutics, Inc. | Pharmaceutical compositions with enhanced permeation |
CN105997955B (zh) | 2016-06-28 | 2017-09-12 | 力品药业(厦门)有限公司 | 一种帕洛诺司琼口腔膜剂及其制备方法 |
US11285306B2 (en) | 2017-01-06 | 2022-03-29 | Morningside Venture Investments Limited | Transdermal drug delivery devices and methods |
KR101912380B1 (ko) * | 2017-03-15 | 2018-10-26 | (주)바이오일레븐 | 프로바이오틱스의 방출 및 프로바이오틱스 효소 활성의 유지를 위한 점막점착성 장치 |
EP3691610A1 (en) | 2017-10-07 | 2020-08-12 | Zim Laboratories Limited | Process for the preparation of bi/multi-layer film, multi-layered film produced thereof and apparatus for producing such multi-layer films |
JP2021515034A (ja) * | 2018-02-22 | 2021-06-17 | アビオール、インコーポレイテッド | 経粘膜フィルム組成物ならびにそれを作製及び使用する方法 |
AU2019279884A1 (en) | 2018-05-29 | 2020-12-10 | Morningside Venture Investments Limited | Drug delivery methods and systems |
EP3863712A4 (en) * | 2018-10-11 | 2022-07-20 | Indivior UK Limited | BUPRENORPHINE FOR TREATING RESPIRATORY DEPRESSION |
US11318107B2 (en) | 2019-02-22 | 2022-05-03 | Avior, Inc. | Pharmaceutical active-containing film delivery device for oral transmucosal administration |
US20210251983A1 (en) | 2020-02-13 | 2021-08-19 | Biodelivery Sciences International, Inc. | Methods of treatment with buprenorphine |
US11179331B1 (en) | 2020-04-21 | 2021-11-23 | Cure Pharmaceutcai Holding Corp | Oral soluble film containing sildenafil citrate |
Family Cites Families (179)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB981372A (en) | 1960-05-04 | 1965-01-27 | Pfizer Ltd | Pharmaceutical formulations for oral administration to animals |
US3640741A (en) | 1970-02-24 | 1972-02-08 | Hollister Inc | Composition containing gel |
US3996934A (en) | 1971-08-09 | 1976-12-14 | Alza Corporation | Medical bandage |
JPS5562012A (en) * | 1978-11-06 | 1980-05-10 | Teijin Ltd | Slow-releasing preparation |
GB2042888B (en) | 1979-03-05 | 1983-09-28 | Teijin Ltd | Preparation for administration to the mucosa of the oral or nasal cavity |
US4713239A (en) | 1979-05-29 | 1987-12-15 | Vsesojuny Kardiologichesky Nauchny Tsentr Adkaemii Meditsinski Nauk Sssr | Antianginal film and method of treating ischemic heart disease |
US4285934A (en) | 1979-07-13 | 1981-08-25 | Tinnell James E | Treatment for herpes virus |
JPS56100714A (en) | 1980-01-16 | 1981-08-12 | Teijin Ltd | Pharmaceutical adhering to oral mucous membrane or nasal mucous membrane |
US4286592A (en) | 1980-02-04 | 1981-09-01 | Alza Corporation | Therapeutic system for administering drugs to the skin |
US4381296A (en) | 1980-06-23 | 1983-04-26 | Tinnell James E | Treatment for herpes virus |
JPS5758615A (en) | 1980-09-26 | 1982-04-08 | Nippon Soda Co Ltd | Film agnent and its preparation |
JPS5770816A (en) * | 1980-10-17 | 1982-05-01 | Ono Pharmaceut Co Ltd | Multilayered film preparation of prostagladin of prolonged action |
JPS57110254A (en) | 1980-12-29 | 1982-07-09 | Teijin Ltd | Coating agent of injured membrane part of oral cavity |
AU8533582A (en) | 1981-07-10 | 1984-01-12 | Reckitt & Colman Products Limited | Stable solutions of buprenorphine |
CH653550A5 (de) | 1981-10-20 | 1986-01-15 | Sandoz Ag | Pharmazeutische zusammensetzung zur verzoegerten freigabe eines medikamentes im mundbereich. |
US4518721A (en) | 1982-03-26 | 1985-05-21 | Richardson-Vicks Inc. | Hydrophilic denture adhesive |
JPS5948409A (ja) | 1982-09-10 | 1984-03-19 | Teikoku Seiyaku Kk | 矯正的歯牙移動促進剤 |
CA1208558A (en) | 1982-10-07 | 1986-07-29 | Kazuo Kigasawa | Soft buccal |
JPS604120A (ja) | 1983-06-22 | 1985-01-10 | Shionogi & Co Ltd | 作用持続型ピナシジル製剤 |
JPS60116630A (ja) | 1983-11-29 | 1985-06-24 | Nitto Electric Ind Co Ltd | 口腔内製剤 |
GB8332556D0 (en) | 1983-12-06 | 1984-01-11 | Reckitt & Colmann Prod Ltd | Analgesic compositions |
US4713246A (en) | 1984-03-19 | 1987-12-15 | Bristol-Myers Company | Etoposide oral dosage form |
DE3580384D1 (de) | 1984-04-09 | 1990-12-13 | Toyo Boseki | Praeparat mit verzoegerter freigabe zum aufbringen auf die schleimhaeute der mundhoehle. |
US5288498A (en) | 1985-05-01 | 1994-02-22 | University Of Utah Research Foundation | Compositions of oral nondissolvable matrixes for transmucosal administration of medicaments |
US5855908A (en) * | 1984-05-01 | 1999-01-05 | University Of Utah Research Foundation | Non-dissolvable drug-containing dosage-forms for use in the transmucosal delivery of a drug to a patient |
DE3587616D1 (de) | 1984-12-22 | 1993-11-11 | Sanol Arznei Schwarz Gmbh | Wirkstoffpflaster. |
US5785989A (en) * | 1985-05-01 | 1998-07-28 | University Utah Research Foundation | Compositions and methods of manufacturing of oral dissolvable medicaments |
US5288497A (en) * | 1985-05-01 | 1994-02-22 | The University Of Utah | Compositions of oral dissolvable medicaments |
JPS61280423A (ja) | 1985-06-05 | 1986-12-11 | Kiyuukiyuu Yakuhin Kogyo Kk | 口腔内粘膜貼付剤 |
JPH0653659B2 (ja) | 1985-07-22 | 1994-07-20 | ニチバン株式会社 | 粘膜付着製剤 |
GB8521494D0 (en) | 1985-08-29 | 1985-10-02 | Zyma Sa | Controlled release tablet |
JPS6256420A (ja) | 1985-09-05 | 1987-03-12 | Teijin Ltd | フイルム状付着性製剤 |
JPH07553B2 (ja) | 1985-12-09 | 1995-01-11 | 佐藤製薬株式会社 | フイルム状製剤 |
US4755386A (en) | 1986-01-22 | 1988-07-05 | Schering Corporation | Buccal formulation |
JPH0729915B2 (ja) | 1986-02-01 | 1995-04-05 | 帝國製薬株式会社 | シ−ト状口腔内貼付剤 |
US4764378A (en) | 1986-02-10 | 1988-08-16 | Zetachron, Inc. | Buccal drug dosage form |
US4713243A (en) | 1986-06-16 | 1987-12-15 | Johnson & Johnson Products, Inc. | Bioadhesive extruded film for intra-oral drug delivery and process |
CH668187A5 (de) | 1986-08-07 | 1988-12-15 | Ciba Geigy Ag | Therapeutisches system mit systemischer wirkung. |
JPH0794384B2 (ja) | 1986-09-01 | 1995-10-11 | 帝国製薬株式会社 | 徐放性口腔内用製剤 |
US5196202A (en) | 1986-09-01 | 1993-03-23 | Teikoku Seiyaku Kabushiki Kaisha | Sustained release dosage form |
US4906463A (en) | 1986-12-22 | 1990-03-06 | Cygnus Research Corporation | Transdermal drug-delivery composition |
JPH0744940B2 (ja) | 1986-12-24 | 1995-05-17 | ライオン株式会社 | 口腔貼付用基材 |
DE3714074A1 (de) | 1987-04-28 | 1988-11-10 | Hoechst Ag | Grundlage fuer schleimhaut- und prothesenhaft-pasten, verfahren zu ihrer herstellung sowie pasten auf basis dieser grundlage |
US4867970A (en) | 1987-05-21 | 1989-09-19 | E. R. Squibb & Sons, Inc. | Moistureless oral drug delivery formulation and method for preparing same |
JPS63310818A (ja) | 1987-06-12 | 1988-12-19 | Sato Seiyaku Kk | シ−ト状口腔粘膜付着製剤 |
US4915948A (en) | 1987-08-31 | 1990-04-10 | Warner-Lambert Company | Tablets having improved bioadhesion to mucous membranes |
US5059189A (en) | 1987-09-08 | 1991-10-22 | E. R. Squibb & Sons, Inc. | Method of preparing adhesive dressings containing a pharmaceutically active ingredient |
JPS6471812A (en) | 1987-09-11 | 1989-03-16 | Sekisui Chemical Co Ltd | Medical application agent |
JP2635336B2 (ja) | 1987-09-30 | 1997-07-30 | 帝國製薬株式会社 | 徐放性口腔内用製剤 |
US4990339A (en) * | 1987-11-16 | 1991-02-05 | H. B. Fuller Company | Dermal treatment film |
US5064654A (en) * | 1989-01-11 | 1991-11-12 | Ciba-Geigy Corporation | Mixed solvent mutually enhanced transdermal therapeutic system |
GB8804164D0 (en) | 1988-02-23 | 1988-03-23 | Tucker J M | Bandage for administering physiologically active compound |
JP2685055B2 (ja) | 1988-03-08 | 1997-12-03 | 帝國製薬株式会社 | シコン含有口腔粘膜貼付剤 |
US4900552A (en) | 1988-03-30 | 1990-02-13 | Watson Laboratories, Inc. | Mucoadhesive buccal dosage forms |
US5081157A (en) | 1988-05-02 | 1992-01-14 | Zila Pharmaceuticals, Inc. | Compositions and in situ methods for forming films on body tissue |
US5081158A (en) | 1988-05-02 | 1992-01-14 | Zila Pharmaceuticals, Inc. | Compositions and in situ methods for forming films on body tissue |
US5047244A (en) | 1988-06-03 | 1991-09-10 | Watson Laboratories, Inc. | Mucoadhesive carrier for delivery of therapeutical agent |
US5236714A (en) | 1988-11-01 | 1993-08-17 | Alza Corporation | Abusable substance dosage form having reduced abuse potential |
US5202128A (en) * | 1989-01-06 | 1993-04-13 | F. H. Faulding & Co. Limited | Sustained release pharmaceutical composition |
JPH0645536B2 (ja) | 1989-01-31 | 1994-06-15 | 日東電工株式会社 | 口腔粘膜貼付剤および口腔粘膜貼付製剤 |
JP2656338B2 (ja) * | 1989-01-31 | 1997-09-24 | 日東電工株式会社 | 口腔粘膜貼付製剤 |
US5750136A (en) | 1989-11-03 | 1998-05-12 | Riker Laboratories, Inc. | Bioadhesive composition and patch |
JP2839164B2 (ja) * | 1989-12-25 | 1998-12-16 | 帝國製薬株式会社 | 消炎鎮痛貼付剤 |
US5298258A (en) | 1989-12-28 | 1994-03-29 | Nitto Denko Corporation | Acrylic oily gel bioadhesive material and acrylic oily gel preparation |
JP2879695B2 (ja) | 1990-02-22 | 1999-04-05 | 日本曹達株式会社 | 口腔内粘膜付着性フィルム製剤 |
JP2930374B2 (ja) | 1990-06-28 | 1999-08-03 | 東亜医薬品工業株式会社 | 口腔内貼着型膜製剤 |
US5332576A (en) | 1991-02-27 | 1994-07-26 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
US5149538A (en) | 1991-06-14 | 1992-09-22 | Warner-Lambert Company | Misuse-resistive transdermal opioid dosage form |
US5192802A (en) | 1991-09-25 | 1993-03-09 | Mcneil-Ppc, Inc. | Bioadhesive pharmaceutical carrier |
US5254345A (en) | 1991-10-11 | 1993-10-19 | Merck & Co., Inc. | Poly(orthocarbonate acetal) bioerodible polymers |
US5298256A (en) | 1992-04-28 | 1994-03-29 | Corint, Ltd. | Desmopressin buccal patch composition |
US5436701A (en) | 1992-06-19 | 1995-07-25 | Canon Kabushiki Kaisha | Image forming method, image forming apparatus and apparatus unit |
GB2273044B (en) | 1992-12-02 | 1997-04-09 | Pacific Chem Co Ltd | Medicinal patches for percutaneous administration |
US5346701A (en) * | 1993-02-22 | 1994-09-13 | Theratech, Inc. | Transmucosal delivery of macromolecular drugs |
WO1995001766A1 (en) | 1993-07-09 | 1995-01-19 | Cygnus Therapeutic Systems | Method and device for providing nicotine replacement therapy transdermally/transbuccally |
AU7568394A (en) | 1993-08-19 | 1995-03-14 | Cygnus Therapeutic Systems | Water-soluble pressure-sensitive mucoadhesive and devices provided therewith for emplacement in a mucosa-lined body cavity |
US5540930A (en) | 1993-10-25 | 1996-07-30 | Pharmos Corporation | Suspension of loteprednol etabonate for ear, eye, or nose treatment |
FR2712807B1 (fr) | 1993-11-24 | 1996-02-23 | Vetoquinol Sa | Composition solide mucoadhésive, thérapeutique ou hygiénique, pour administration par application sur la muqueuse buccale ou nasale . |
DE4341442C2 (de) | 1993-12-04 | 1998-11-05 | Lohmann Therapie Syst Lts | Vorrichtung zur kontrollierten Freisetzung von Wirkstoffen sowie ihre Verwendung |
US5466465A (en) | 1993-12-30 | 1995-11-14 | Harrogate Holdings, Limited | Transdermal drug delivery system |
US5679714A (en) | 1995-06-07 | 1997-10-21 | Weg; Stuart L. | Administration of ketamine for detoxification and treatment of tobacco addiction |
DE69523745T2 (de) | 1994-03-21 | 2002-08-08 | John Brown Thomsen | Gel zur behandlung von hauterkrankungen und zur desinfizierung von haut |
WO1996000072A1 (en) | 1994-06-23 | 1996-01-04 | The Procter & Gamble Company | Treatment of nicotine craving and/or smoking withdrawal symptoms with a transdermal or transmucosal composition containing nicotine and caffeine or xanthine |
DE4446600A1 (de) * | 1994-12-24 | 1996-06-27 | Lohmann Therapie Syst Lts | Transdermale Resorption von Wirkstoffen aus unterkühlten Schmelzen |
EP0750905B1 (en) * | 1995-06-27 | 2003-01-02 | Kao Corporation | Patch comprising water soluble adhesive sheet |
US5849322A (en) | 1995-10-23 | 1998-12-15 | Theratech, Inc. | Compositions and methods for buccal delivery of pharmaceutical agents |
JP2791317B2 (ja) | 1995-12-26 | 1998-08-27 | 株式会社三和化学研究所 | 多層フィルム製剤 |
FR2742989B1 (fr) | 1995-12-29 | 1998-01-23 | Adir | Composition pharmaceutique bioadhesive pour la liberation controlee de principes actifs |
CN1230123A (zh) * | 1996-07-11 | 1999-09-29 | 荷兰发马克有限公司 | 含碱性药物的酸加成盐的药物组合物 |
US5985317A (en) | 1996-09-06 | 1999-11-16 | Theratech, Inc. | Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents |
US5800832A (en) | 1996-10-18 | 1998-09-01 | Virotex Corporation | Bioerodable film for delivery of pharmaceutical compounds to mucosal surfaces |
DE19646392A1 (de) | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
DE19652188C2 (de) | 1996-12-16 | 2002-02-14 | Lohmann Therapie Syst Lts | Flache Arzneizubereitung zur Applikation und Freisetzung von Buprenorphin oder einer pharmakologisch vergleichbaren Substanz in der Mundhöhle und Verfahren zu ihrer Herstellung |
US6248358B1 (en) | 1998-08-25 | 2001-06-19 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets and methods of making and using the same |
RU2234337C2 (ru) | 1997-09-26 | 2004-08-20 | Ноувен Фамэсьютикэлз, Инк. | Биоадгезивная композиция (варианты), способ ее получения (варианты), устройство для доставки через слизистую оболочку активного агента, способ пролонгированного местного введения одного или более активных агентов субъекту (варианты) и способ сокращения времени, требуемого для приклеивания композиции к слизистой ткани |
US20040018241A1 (en) * | 1997-09-26 | 2004-01-29 | Noven Pharmaceuticals, Inc. | Bioadhesive compositions and methods for topical administration of active agents |
US20050048102A1 (en) * | 1997-10-16 | 2005-03-03 | Virotex Corporation | Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces |
US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
JP2001526228A (ja) | 1997-12-22 | 2001-12-18 | ユーロ−セルティーク,エス.エイ. | オピオイド作動薬/拮抗薬の併用 |
BR9813826A (pt) * | 1997-12-22 | 2000-10-10 | Euro Celtique Sa | Potencial de uso abusivo de administração oral de opióide analgésico |
US6200604B1 (en) | 1998-03-27 | 2001-03-13 | Cima Labs Inc. | Sublingual buccal effervescent |
ES2237104T3 (es) | 1998-04-29 | 2005-07-16 | Virotex Corporation | Dispositivo portador de productos farmaceuticos adecuado para el aporte de compuestos farmaceuticos a superficies mucosas. |
SE9803239D0 (sv) | 1998-09-24 | 1998-09-24 | Diabact Ab | Composition for the treatment of acute pain |
IL142168A0 (en) * | 1998-10-02 | 2002-03-10 | 3M Innovative Properties Co | Mucosal originated drug delivery systems and animal applications |
ES2237415T5 (es) | 1999-01-14 | 2008-12-16 | Noven Pharmaceuticals, Inc. | Composiciones dermicas. |
US20030170195A1 (en) | 2000-01-10 | 2003-09-11 | Noven Pharmaceuticals, Inc. | Compositions and methods for drug delivery |
US6552024B1 (en) * | 1999-01-21 | 2003-04-22 | Lavipharm Laboratories Inc. | Compositions and methods for mucosal delivery |
US6284262B1 (en) | 1999-01-26 | 2001-09-04 | Virgil A. Place | Compact dosage unit for buccal administration of a pharmacologically active agent |
US6319510B1 (en) * | 1999-04-20 | 2001-11-20 | Alayne Yates | Gum pad for delivery of medication to mucosal tissues |
DE19932603A1 (de) * | 1999-07-13 | 2001-01-25 | Gruenenthal Gmbh | Wirkstoffhaltiger Mehrschichtfilm aus in situ vernetzten hydrophilen Polymeren |
US6264981B1 (en) * | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
DE19960154A1 (de) * | 1999-12-14 | 2001-07-12 | Lohmann Therapie Syst Lts | Flache Arzneizubereitung zur transmucosalen Verabreichung von Oxycodon oder einem vergleichbaren Wirkstoff in der Mundhöhle, für die Anwendung in der Schmerztherapie und Suchttherapie |
US6582724B2 (en) * | 1999-12-16 | 2003-06-24 | Dermatrends, Inc. | Dual enhancer composition for topical and transdermal drug delivery |
US20030104041A1 (en) * | 1999-12-16 | 2003-06-05 | Tsung-Min Hsu | Transdermal and topical administration of drugs using basic permeation enhancers |
US20050074487A1 (en) * | 1999-12-16 | 2005-04-07 | Tsung-Min Hsu | Transdermal and topical administration of drugs using basic permeation enhancers |
US20030124176A1 (en) * | 1999-12-16 | 2003-07-03 | Tsung-Min Hsu | Transdermal and topical administration of drugs using basic permeation enhancers |
US6719997B2 (en) * | 2000-06-30 | 2004-04-13 | Dermatrends, Inc. | Transdermal administration of pharmacologically active amines using hydroxide-releasing agents as permeation enhancers |
WO2001058451A1 (en) | 2000-02-08 | 2001-08-16 | Euro-Celtique, S.A. | Tamper-resistant oral opioid agonist formulations |
US6716449B2 (en) * | 2000-02-08 | 2004-04-06 | Euro-Celtique S.A. | Controlled-release compositions containing opioid agonist and antagonist |
CA2408106A1 (en) | 2000-05-05 | 2001-11-15 | Pain Therapeutics, Inc. | Opioid antagonist compositions and dosage forms |
WO2001089476A1 (en) * | 2000-05-19 | 2001-11-29 | Npd Llc | Chewing gums, lozenges, candies, tablets, liquids, and sprays for efficient delivery of medications and dietary supplements |
GB0026137D0 (en) | 2000-10-25 | 2000-12-13 | Euro Celtique Sa | Transdermal dosage form |
US6969374B2 (en) | 2001-02-09 | 2005-11-29 | Hager & Werken Gmbh & Co. Kg | Injection syringe and disposal container for injection needle units |
US20020160043A1 (en) * | 2001-02-27 | 2002-10-31 | Dennis Coleman | Compositions and method of manufacture for oral dissolvable dosage forms |
JP4850346B2 (ja) * | 2001-03-15 | 2012-01-11 | 救急薬品工業株式会社 | 粘膜貼付剤 |
SI2316439T1 (sl) | 2001-05-01 | 2015-10-30 | Euro-Celtique S.A. | Proti zlorabi odporni transdermalni sistemi, ki vsebujejo opioid |
US20030065002A1 (en) | 2001-05-11 | 2003-04-03 | Endo Pharmaceuticals, Inc. | Abuse-resistant controlled-release opioid dosage form |
US7157103B2 (en) | 2001-08-06 | 2007-01-02 | Euro-Celtique S.A. | Pharmaceutical formulation containing irritant |
SI1414451T1 (sl) | 2001-08-06 | 2009-10-31 | Euro Celtique Sa | Formulacije opioidnega agonista s sproščanja sposobnim in sekvestriranim antagonistom |
US7144587B2 (en) | 2001-08-06 | 2006-12-05 | Euro-Celtique S.A. | Pharmaceutical formulation containing opioid agonist, opioid antagonist and bittering agent |
US20030044458A1 (en) | 2001-08-06 | 2003-03-06 | Curtis Wright | Oral dosage form comprising a therapeutic agent and an adverse-effect agent |
US6585997B2 (en) * | 2001-08-16 | 2003-07-01 | Access Pharmaceuticals, Inc. | Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds |
US7666337B2 (en) | 2002-04-11 | 2010-02-23 | Monosol Rx, Llc | Polyethylene oxide-based films and drug delivery systems made therefrom |
US7910641B2 (en) | 2001-10-12 | 2011-03-22 | Monosol Rx, Llc | PH modulated films for delivery of actives |
US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
US20040033253A1 (en) | 2002-02-19 | 2004-02-19 | Ihor Shevchuk | Acyl opioid antagonists |
US7666876B2 (en) * | 2002-03-19 | 2010-02-23 | Vernalis (R&D) Limited | Buprenorphine formulations for intranasal delivery |
US20030194420A1 (en) * | 2002-04-11 | 2003-10-16 | Richard Holl | Process for loading a drug delivery device |
EP1515674A4 (en) | 2002-05-13 | 2008-04-09 | Endo Pharmaceuticals Inc | AGAINST MISUSE PROTECTED SOLID OPIOID DOSAGE FORM |
NZ537180A (en) | 2002-06-10 | 2008-03-28 | Euro Celtique Sa | Disposal systems of transdermal delivery devices to prevent misuse of the active agents contained therein |
SI1530469T1 (sl) | 2002-08-20 | 2009-06-30 | Euro Celtique Sa | Transdermalna odmerna oblika, ki obsega aktivno sredstvo in antagonist v obliki soli in v obliki proste baze |
CA2504283A1 (en) * | 2002-10-31 | 2004-05-21 | Umd, Inc. | Therapeutic compositions for drug delivery to and through covering epithelia |
US20050013845A1 (en) | 2002-11-12 | 2005-01-20 | Warren Stephen L. | Adhesive bioerodible ocular drug delivery system |
US20040110781A1 (en) * | 2002-12-05 | 2004-06-10 | Harmon Troy M. | Pharmaceutical compositions containing indistinguishable drug components |
WO2004054553A1 (en) | 2002-12-13 | 2004-07-01 | Euro-Celtique S.A. | Transdermal buprenorphine dosage regimen for analgesia |
US20040253307A1 (en) | 2003-02-04 | 2004-12-16 | Brian Hague | Sugar-free oral transmucosal solid dosage forms and uses thereof |
US20040191301A1 (en) | 2003-03-27 | 2004-09-30 | Van Duren Albert Philip | Transdermal device having a phase change material |
US20040213828A1 (en) | 2003-04-23 | 2004-10-28 | Smith David J. | Pain relief lollipop compositions and methods |
US20040219195A1 (en) | 2003-04-30 | 2004-11-04 | 3M Innovative Properties Company | Abuse-resistant transdermal dosage form |
RS20050812A (en) | 2003-04-30 | 2007-12-31 | Purdue Pharma L.P., | Tamper resistant transdermal dosage form |
US7182955B2 (en) | 2003-04-30 | 2007-02-27 | 3M Innovative Properties Company | Abuse-resistant transdermal dosage form |
JP5137286B2 (ja) * | 2003-06-10 | 2013-02-06 | 帝國製薬株式会社 | フェンタニル含有口腔粘膜貼付剤 |
US7068445B2 (en) | 2003-07-11 | 2006-06-27 | Matsushita Electric Industrial Co., Ltd. | Optical pickup lens device and information recording and reproducing device using the same |
CA2535846A1 (en) * | 2003-08-15 | 2005-02-24 | Qlt Usa, Inc. | Adhesive bioerodible transmucosal drug delivery system |
US20050042281A1 (en) * | 2003-08-21 | 2005-02-24 | Singh Nikhilesh N. | Compositions for delivering therapeutic agents across the oral mucosa |
US20080317828A1 (en) | 2003-09-24 | 2008-12-25 | Kazuyoshi Furusawa | Fentanyl compound-containing edible patch to be applied to oral mucosa |
BRPI0416063A (pt) | 2003-10-28 | 2007-01-02 | Noven Pharma | composição de administração de medicamento por via transdérmica, método de produzir a composição de administração de medicamento por via transdérmica e método de controle de fluxo de um medicmanto de uma composição de administração de medicamento dérmica |
WO2005044243A2 (en) | 2003-10-30 | 2005-05-19 | Alza Corporation | Transdermal analgesic systems having reduced abuse potential |
ES2281851T3 (es) | 2003-12-09 | 2007-10-01 | Euro-Celtique S.A. | Forma de dosis co-extruida resistente a la manipulacion conteniendo un agente activo y un agente adverso y proceso para preparar el mismo. |
CA2552241C (en) | 2003-12-30 | 2013-10-01 | Durect Corporation | Co-polymeric devices for controlled release of active agents |
PL1718258T3 (pl) | 2004-02-23 | 2009-08-31 | Euro Celtique Sa | Odporne na nadużywanie transdermalne urządzenie do podawania opioidu |
EP1584335A3 (en) | 2004-04-05 | 2006-02-22 | Laboratorios Del Dr. Esteve, S.A. | Active substance combination comprising a carbinol composition and an opioid |
US20060051413A1 (en) * | 2004-09-08 | 2006-03-09 | Chow Sing S M | Method of enhancing absorptions of transmucosal administration formulations |
CN101065014A (zh) | 2004-09-23 | 2007-10-31 | 亚历山大·米哈洛 | 通过诱导逆适应调节神经递质系统的方法 |
US7827983B2 (en) | 2004-12-20 | 2010-11-09 | Hewlett-Packard Development Company, L.P. | Method for making a pharmaceutically active ingredient abuse-prevention device |
DE102005007859A1 (de) | 2005-02-21 | 2006-08-24 | Lts Lohmann Therapie-Systeme Ag | Vefahren für eine medikamentöse Kombinations-Behandlung, sowie hierfür geeignete Arzneimittel-Kombinationen |
GB0514043D0 (en) | 2005-07-08 | 2005-08-17 | Arakis Ltd | Fentanyl formulation |
EP1968539A2 (en) * | 2005-12-13 | 2008-09-17 | Biodelivery Sciences International, Inc. | Abuse resistant transmucosal drug delivery device |
HUE027395T2 (hu) | 2006-07-21 | 2016-10-28 | Biodelivery Sciences Int Inc | Eszközök nyálkahártyán keresztül történõ bejuttatására, javított felszívódással |
EP1897543A1 (en) | 2006-08-30 | 2008-03-12 | Euro-Celtique S.A. | Buprenorphine- wafer for drug substitution therapy |
DK2248519T3 (en) | 2006-10-02 | 2018-01-02 | Applied Pharma Res | Non-mucoadhesive film dosage forms |
US20090270438A1 (en) * | 2006-10-18 | 2009-10-29 | Clive Booles | Novel compositions and formulations |
GB0620661D0 (en) | 2006-10-18 | 2006-11-29 | Pharmasol Ltd | Novel compounds |
AU2008216867B2 (en) | 2007-02-09 | 2014-01-30 | Durect Corporation | Transoral dosage forms comprising sufentanil and naloxone |
GB2447015A (en) | 2007-03-01 | 2008-09-03 | Reckitt Benckiser Healthcare | Analgesic composition comprising a specific ratio of buprenorphine and naltrexone |
US20110189259A1 (en) | 2008-06-23 | 2011-08-04 | Biodelivery Sciences International, Inc. | Multidirectional mucosal delivery devices and methods of use |
US8475832B2 (en) | 2009-08-07 | 2013-07-02 | Rb Pharmaceuticals Limited | Sublingual and buccal film compositions |
MX352959B (es) * | 2011-08-18 | 2017-12-15 | Biodelivery Sciences Int Inc | Dispositivos mucoadhesivos resistentes al abuso para el suministro de buprenorfina. |
US9901539B2 (en) * | 2011-12-21 | 2018-02-27 | Biodelivery Sciences International, Inc. | Transmucosal drug delivery devices for use in chronic pain relief |
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2016
- 2016-04-18 HR HRP20160405TT patent/HRP20160405T1/hr unknown
- 2016-06-30 US US15/198,961 patent/US9597288B2/en active Active
- 2016-07-18 US US15/212,912 patent/US9655843B2/en active Active
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2017
- 2017-02-10 US US15/429,385 patent/US20170312218A1/en not_active Abandoned
- 2017-03-14 NO NO20170380A patent/NO344719B1/no not_active IP Right Cessation
- 2017-04-11 US US15/484,682 patent/US20170216278A1/en not_active Abandoned
- 2017-11-01 US US15/801,302 patent/US20190111048A9/en not_active Abandoned
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2019
- 2019-04-25 US US16/394,647 patent/US20190365739A1/en not_active Abandoned
- 2019-06-10 RU RU2019118034A patent/RU2019118034A/ru unknown
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2020
- 2020-03-06 NO NO20200273A patent/NO20200273A1/no not_active Application Discontinuation
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2021
- 2021-03-22 US US17/209,119 patent/US20210275520A1/en not_active Abandoned
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2023
- 2023-07-03 US US18/346,474 patent/US20240066024A1/en not_active Abandoned
- 2023-09-25 US US18/473,524 patent/US20240156809A1/en not_active Abandoned
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Date | Code | Title | Description |
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PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20230723 |