HK1021746A1 - Modulators of tissue regeneration. - Google Patents
Modulators of tissue regeneration.Info
- Publication number
- HK1021746A1 HK1021746A1 HK00100386A HK00100386A HK1021746A1 HK 1021746 A1 HK1021746 A1 HK 1021746A1 HK 00100386 A HK00100386 A HK 00100386A HK 00100386 A HK00100386 A HK 00100386A HK 1021746 A1 HK1021746 A1 HK 1021746A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- modulators
- tissue regeneration
- purified
- new
- nucleic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Optics & Photonics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1822896P | 1996-05-24 | 1996-05-24 | |
US2344296P | 1996-08-23 | 1996-08-23 | |
PCT/US1997/009303 WO1997044460A1 (en) | 1996-05-24 | 1997-05-23 | Modulators of tissue regeneration |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1021746A1 true HK1021746A1 (en) | 2000-06-30 |
Family
ID=26690881
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK00100386A HK1021746A1 (en) | 1996-05-24 | 2000-01-21 | Modulators of tissue regeneration. |
Country Status (27)
Country | Link |
---|---|
US (4) | US6664385B1 (pt) |
EP (2) | EP0907735B9 (pt) |
JP (3) | JP4602482B2 (pt) |
CN (1) | CN1147584C (pt) |
AT (1) | ATE318903T1 (pt) |
AU (1) | AU712289B2 (pt) |
BG (1) | BG64678B1 (pt) |
BR (1) | BR9709115A (pt) |
CA (1) | CA2257851C (pt) |
CZ (1) | CZ295936B6 (pt) |
DE (1) | DE69735364T3 (pt) |
DK (1) | DK0907735T5 (pt) |
EA (1) | EA004402B1 (pt) |
EE (1) | EE04817B1 (pt) |
ES (1) | ES2258793T5 (pt) |
HK (1) | HK1021746A1 (pt) |
HU (1) | HU226205B1 (pt) |
IL (1) | IL127162A (pt) |
IS (1) | IS2636B (pt) |
NO (2) | NO327597B1 (pt) |
NZ (1) | NZ336467A (pt) |
PL (1) | PL188826B1 (pt) |
PT (1) | PT907735E (pt) |
SI (1) | SI0907735T2 (pt) |
SK (1) | SK285461B6 (pt) |
TR (1) | TR199802421T2 (pt) |
WO (1) | WO1997044460A1 (pt) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU226205B1 (en) * | 1996-05-24 | 2008-06-30 | Biogen Idec Ma | Modulators of tissue regeneration |
AU7592998A (en) * | 1997-05-23 | 1998-12-11 | Biogen, Inc. | Modulators of tissue regeneration |
AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
JP4187413B2 (ja) | 1998-03-20 | 2008-11-26 | コモンウェルス サイエンティフィック アンドインダストリアル リサーチ オーガナイゼーション | 遺伝子発現の制御 |
US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
EP1160321A1 (en) * | 2000-05-31 | 2001-12-05 | Sanofi-Synthelabo | Kidney Injury Novel Gene-1: Isolation and therapeutic applications |
DE60137934D1 (de) * | 2000-06-16 | 2009-04-23 | Biogen Idec Inc | Renale regulatorische elemente und deren verwendung |
US6812002B2 (en) | 2000-08-30 | 2004-11-02 | Pfizer Inc. | Osteoactivin protein and nucleic acids encoding the same, compositions and methods of stimulating bone differentiation |
AU2002305785B2 (en) | 2001-06-01 | 2008-01-17 | Biogen Ma Inc. | Molecules and methods for inhibiting shedding of KIM-1 |
US8709412B2 (en) | 2001-06-29 | 2014-04-29 | The Board Of Trustees Of The Leland Stanford Junior University | Modulation of TIM receptor activity in combination with cytoreductive therapy |
KR20040014997A (ko) | 2001-06-29 | 2004-02-18 | 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 | T 세포 조절 유전자 및 그것의 사용방법 |
US20050014687A1 (en) * | 2002-03-19 | 2005-01-20 | Anderson David W. | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
EP2025345A1 (en) | 2002-12-30 | 2009-02-18 | Biogen Idec MA Inc. | KIM-1 antagonists and use to modulate immune system |
US8067544B2 (en) | 2003-03-19 | 2011-11-29 | Curagen Corporation | Antibodies against T cell immunoglobulin domain and mucin domain 1 (TIM-1) antigen and uses thereof |
CN102183656B (zh) * | 2003-03-27 | 2014-04-16 | 儿童医院医疗中心 | 用于检测肾小管细胞损伤的早发的方法和试剂盒 |
US20050272101A1 (en) * | 2004-06-07 | 2005-12-08 | Prasad Devarajan | Method for the early detection of renal injury |
EP1750500B1 (en) | 2004-05-06 | 2015-07-08 | The Trustees of Columbia University in the City of New York | Ngal for reduction and amelioration of ischemic and nephrotoxic injuries |
RU2283666C9 (ru) * | 2004-05-14 | 2007-03-10 | Бизяев Алексей Вячеславович | Средство для активации восстановления структуры и функции поврежденных тканей и органов |
US20060003345A1 (en) * | 2004-06-30 | 2006-01-05 | Pfizer Inc | RNA bioassay |
ES2703434T3 (es) * | 2004-12-20 | 2019-03-08 | Antibodyshop As | Determinación de lipocalina asociada a gelatinasa de neutrófilos (NGAL) como marcador diagnóstico para trastornos renales |
WO2006094134A2 (en) | 2005-03-02 | 2006-09-08 | Biogen Idec Ma Inc. | Kim-1 antibodies for treatment of th2-mediated conditions |
US20070037232A1 (en) * | 2005-03-31 | 2007-02-15 | Barasch Jonathan M | Detection of NGAL in chronic renal disease |
US20080090304A1 (en) * | 2006-10-13 | 2008-04-17 | Barasch Jonathan Matthew | Diagnosis and monitoring of chronic renal disease using ngal |
AU2006315580A1 (en) | 2005-11-10 | 2007-05-24 | Curagen Corporation | Method of treating ovarian and renal cancer using antibodies against T cell immunoglobulin domain and mucin domain 1 (TIM-1) antigen |
ATE539351T1 (de) | 2006-05-30 | 2012-01-15 | Antibodyshop As | Verfahren zur schnellen beurteilung der schwere eines traumas |
EP2602624A1 (en) * | 2006-08-07 | 2013-06-12 | Antibodyshop A/S | Diagnostic test to exclude significant renal injury |
US8313919B2 (en) * | 2007-03-21 | 2012-11-20 | Bioporto Diagnostics A/S | Diagnostic test for renal injury |
US8846036B2 (en) | 2007-10-19 | 2014-09-30 | Abbott Laboratories | Antibodies that bind to mammalian NGAL and uses thereof |
US20090297479A1 (en) * | 2008-03-28 | 2009-12-03 | Kiyoshi Ariizumi | Dc-hil conjugates for treatment of t-cell disorders |
CA2735587A1 (en) * | 2008-08-28 | 2010-03-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
WO2010025434A1 (en) * | 2008-08-29 | 2010-03-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
JP2012506537A (ja) * | 2008-10-21 | 2012-03-15 | アスチュート メディカル,インコーポレイテッド | 腎損傷および腎不全の診断および予後のための方法および組成物 |
US20110207161A1 (en) * | 2008-10-21 | 2011-08-25 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
US8993250B2 (en) | 2008-11-10 | 2015-03-31 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
MX2011005379A (es) * | 2008-11-22 | 2011-06-09 | Astute Medical Inc | Metodos y composiciones para diagnosis y prognosis de lesion renal y falla renal. |
BRPI1007483B1 (pt) * | 2009-01-28 | 2021-11-30 | Bio Preventive Medicine Corporation | Método de diagnóstico de nefropatia in vitro, método in vitro para o monitoramento de progresso de nefropatia, método in vitro para o monitoramento da eficácia de um tratamento de nefropatia, método in vitro de avaliação de toxicidade renal de um agente e kit para diagnóstico de nefropatia |
WO2011017654A1 (en) | 2009-08-07 | 2011-02-10 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
US9229010B2 (en) | 2009-02-06 | 2016-01-05 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
US20120264148A1 (en) * | 2009-08-07 | 2012-10-18 | Dashurie Nezieri | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
EA201290192A1 (ru) | 2009-11-07 | 2013-02-28 | Астьют Медикал, Инк. | Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности |
ES2592386T3 (es) | 2009-12-20 | 2016-11-29 | Astute Medical, Inc. | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal |
MX341191B (es) | 2010-02-05 | 2016-08-10 | Astute Medical Inc | Metodos y composiciones para diagnostico y prognosis de lesion renal y falla renal. |
KR20140051754A (ko) | 2010-02-26 | 2014-05-02 | 아스튜트 메디컬 인코포레이티드 | 신장 손상 및 신부전의 진단 및 예후를 위한 방법 및 조성물 |
WO2011149962A1 (en) | 2010-05-24 | 2011-12-01 | The Trustees Of Columbia University In The City Of New York | Mutant ngal proteins and uses thereof |
EP2585825B1 (en) | 2010-06-23 | 2018-01-10 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
EP3339860A1 (en) | 2010-06-23 | 2018-06-27 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
WO2012108830A1 (en) * | 2011-02-09 | 2012-08-16 | Lavivo Ab | Synbiotic compositions for restoration and reconstitution of gut microbiota |
ES2933570T3 (es) | 2011-12-08 | 2023-02-10 | Astute Medical Inc | Métodos y composiciones para el diagnóstico y el pronóstico de una lesión renal y de una insuficiencia renal |
EP2925337B1 (en) | 2012-11-21 | 2019-07-03 | The Trustees of Columbia University in the City of New York | Mutant ngal proteins and uses thereof |
ES2681955T3 (es) | 2013-01-17 | 2018-09-17 | Astute Medical, Inc. | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal |
US10420337B2 (en) | 2013-03-15 | 2019-09-24 | Lifeline Scientific, Inc. | Transporter with a glucose sensor for determining viability of an organ or tissue |
WO2015134671A1 (en) | 2014-03-04 | 2015-09-11 | Targeson, Inc. | Molecular imaging contrast agents and uses thereof |
JP2019523889A (ja) | 2016-06-06 | 2019-08-29 | アスチュート メディカル,インコーポレイテッド | インスリン様増殖因子結合タンパク質7およびメタロプロテアーゼ2の組織阻害剤を使用する急性腎臓傷害の管理 |
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US2003A (en) * | 1841-03-12 | Improvement in horizontal windivhlls | ||
US5019368A (en) * | 1989-02-23 | 1991-05-28 | Cancer Biologics, Inc. | Detection of necrotic malignant tissue and associated therapy |
GB9122820D0 (en) * | 1991-10-28 | 1991-12-11 | Wellcome Found | Stabilised antibodies |
AU4116793A (en) * | 1992-04-24 | 1993-11-29 | Board Of Regents, The University Of Texas System | Recombinant production of immunoglobulin-like domains in prokaryotic cells |
CA2166313A1 (en) * | 1994-02-14 | 1995-08-17 | John N. Simons | Non-a, non-b, non-c, non-d, non-e hepatitis reagents and methods for their use |
US5622861A (en) * | 1994-08-05 | 1997-04-22 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA encoding hepatitis A virus receptor |
CA2196892A1 (en) * | 1994-08-18 | 1996-02-29 | The Trustees Of Columbia University | Unique associated kaposi's sarcoma virus sequences and uses thereof |
US6069230A (en) * | 1994-11-10 | 2000-05-30 | Promega Corporation | High level expression and facile purification of proteins, peptides and conjugates for immunization, purification and detection applications |
US6066322A (en) * | 1995-03-03 | 2000-05-23 | Millennium Pharmaceuticals, Inc. | Methods for the treatment of immune disorders |
HU226205B1 (en) * | 1996-05-24 | 2008-06-30 | Biogen Idec Ma | Modulators of tissue regeneration |
DE60137934D1 (de) * | 2000-06-16 | 2009-04-23 | Biogen Idec Inc | Renale regulatorische elemente und deren verwendung |
AU2002305785B2 (en) * | 2001-06-01 | 2008-01-17 | Biogen Ma Inc. | Molecules and methods for inhibiting shedding of KIM-1 |
US7838220B2 (en) * | 2001-06-29 | 2010-11-23 | The Board Of Trustees Of The Leland Stanford Junior University | T cell regulatory genes associated with immune disease |
KR20040014997A (ko) * | 2001-06-29 | 2004-02-18 | 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 | T 세포 조절 유전자 및 그것의 사용방법 |
US7215871B2 (en) * | 2001-07-27 | 2007-05-08 | Thomson Licensing | Changing a playback speed for video presentation recorded in a field structure format |
US7687454B2 (en) * | 2001-12-03 | 2010-03-30 | The University Of British Columbia | Effectors of innate immunity determination |
US7470428B2 (en) * | 2002-01-30 | 2008-12-30 | The Brigham And Women's Hospital, Inc. | Compositions and methods related to TIM-3, a Th1-specific cell surface molecule |
US20050014687A1 (en) * | 2002-03-19 | 2005-01-20 | Anderson David W. | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
EP2025345A1 (en) * | 2002-12-30 | 2009-02-18 | Biogen Idec MA Inc. | KIM-1 antagonists and use to modulate immune system |
TW200539890A (en) * | 2004-03-12 | 2005-12-16 | Brigham & Womens Hospital | Methods of modulating immune responses by modulating tim-1, tim-2 and tim-4 function |
AU2005231685A1 (en) * | 2004-03-24 | 2005-10-20 | Telos Pharmaceuticals Llc | Compositions as adjuvants to improve immune responses to vaccines and methods of use |
-
1997
- 1997-05-23 HU HU9902770A patent/HU226205B1/hu unknown
- 1997-05-23 EA EA199801044A patent/EA004402B1/ru not_active IP Right Cessation
- 1997-05-23 WO PCT/US1997/009303 patent/WO1997044460A1/en active IP Right Grant
- 1997-05-23 AU AU35676/97A patent/AU712289B2/en not_active Expired
- 1997-05-23 PT PT97932145T patent/PT907735E/pt unknown
- 1997-05-23 EP EP97932145A patent/EP0907735B9/en not_active Expired - Lifetime
- 1997-05-23 SK SK1609-98A patent/SK285461B6/sk not_active IP Right Cessation
- 1997-05-23 AT AT97932145T patent/ATE318903T1/de active
- 1997-05-23 IL IL127162A patent/IL127162A/en not_active IP Right Cessation
- 1997-05-23 TR TR1998/02421T patent/TR199802421T2/xx unknown
- 1997-05-23 NZ NZ336467A patent/NZ336467A/xx not_active IP Right Cessation
- 1997-05-23 EP EP05111979A patent/EP1655367A1/en not_active Withdrawn
- 1997-05-23 CZ CZ19983813A patent/CZ295936B6/cs not_active IP Right Cessation
- 1997-05-23 ES ES97932145T patent/ES2258793T5/es not_active Expired - Lifetime
- 1997-05-23 DE DE69735364T patent/DE69735364T3/de not_active Expired - Lifetime
- 1997-05-23 EE EE9800409A patent/EE04817B1/xx unknown
- 1997-05-23 JP JP54298697A patent/JP4602482B2/ja not_active Expired - Lifetime
- 1997-05-23 BR BR9709115A patent/BR9709115A/pt not_active Application Discontinuation
- 1997-05-23 CA CA2257851A patent/CA2257851C/en not_active Expired - Lifetime
- 1997-05-23 CN CNB971958289A patent/CN1147584C/zh not_active Expired - Lifetime
- 1997-05-23 PL PL97330313A patent/PL188826B1/pl unknown
- 1997-05-23 DK DK97932145.2T patent/DK0907735T5/da active
- 1997-05-23 SI SI9730732T patent/SI0907735T2/sl unknown
-
1998
- 1998-11-20 IS IS4902A patent/IS2636B/is unknown
- 1998-11-20 NO NO985427A patent/NO327597B1/no not_active IP Right Cessation
- 1998-11-23 US US09/197,970 patent/US6664385B1/en not_active Expired - Lifetime
- 1998-11-30 BG BG102967A patent/BG64678B1/bg unknown
-
2000
- 2000-01-21 HK HK00100386A patent/HK1021746A1/xx not_active IP Right Cessation
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2003
- 2003-09-04 US US10/655,506 patent/US20050089868A1/en not_active Abandoned
-
2006
- 2006-08-08 US US11/463,239 patent/US20070141590A1/en not_active Abandoned
- 2006-08-08 US US11/463,227 patent/US20060286031A1/en not_active Abandoned
-
2007
- 2007-09-11 JP JP2007236021A patent/JP4316640B2/ja not_active Expired - Lifetime
-
2008
- 2008-07-18 JP JP2008187615A patent/JP2009039111A/ja not_active Withdrawn
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2009
- 2009-03-03 NO NO20090945A patent/NO20090945L/no not_active Application Discontinuation
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Effective date: 20170522 |