HK1021641A1 - N-substituted indole-3-glyoxylamid with antiasthmatic, antiallergic and immunosuppressive/immunomodulating effect - Google Patents

N-substituted indole-3-glyoxylamid with antiasthmatic, antiallergic and immunosuppressive/immunomodulating effect

Info

Publication number
HK1021641A1
HK1021641A1 HK00100629A HK00100629A HK1021641A1 HK 1021641 A1 HK1021641 A1 HK 1021641A1 HK 00100629 A HK00100629 A HK 00100629A HK 00100629 A HK00100629 A HK 00100629A HK 1021641 A1 HK1021641 A1 HK 1021641A1
Authority
HK
Hong Kong
Prior art keywords
glyoxylamid
antiasthmatic
antiallergic
immunosuppressive
substituted indole
Prior art date
Application number
HK00100629A
Other languages
English (en)
Inventor
Guillaume Lebaut
Cecilia Menciu
Bernhard Kutscher
Peter Emig
Stefan Szelenyi
Kay Brune
Original Assignee
Asta Medicia Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medicia Ag filed Critical Asta Medicia Ag
Publication of HK1021641A1 publication Critical patent/HK1021641A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
HK00100629A 1996-09-06 2000-02-02 N-substituted indole-3-glyoxylamid with antiasthmatic, antiallergic and immunosuppressive/immunomodulating effect HK1021641A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19636150A DE19636150A1 (de) 1996-09-06 1996-09-06 N-substituierte Indol-3-glyoxylamide mit antiasthmatischer, antiallergischer und immunsuppressiver/immunmodulierender Wirkung
PCT/EP1997/004474 WO1998009946A1 (de) 1996-09-06 1997-08-16 N-substituierte indol-3-glyoxylamide mit antiasthmatischer, antiallergischer und immunsuppressiver/immunmodulierender wirkung

Publications (1)

Publication Number Publication Date
HK1021641A1 true HK1021641A1 (en) 2000-06-23

Family

ID=7804772

Family Applications (3)

Application Number Title Priority Date Filing Date
HK00100629A HK1021641A1 (en) 1996-09-06 2000-02-02 N-substituted indole-3-glyoxylamid with antiasthmatic, antiallergic and immunosuppressive/immunomodulating effect
HK04107115.1A HK1064379A1 (en) 1996-09-06 2004-09-17 N-substituted indole-3-glyoxylamid with antiasthmatic, antiallergic and immunosuppressive/immunomodulating effect
HK09100395.2A HK1123280A1 (en) 1996-09-06 2009-01-15 N-substituted indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/immuno-modulating action

Family Applications After (2)

Application Number Title Priority Date Filing Date
HK04107115.1A HK1064379A1 (en) 1996-09-06 2004-09-17 N-substituted indole-3-glyoxylamid with antiasthmatic, antiallergic and immunosuppressive/immunomodulating effect
HK09100395.2A HK1123280A1 (en) 1996-09-06 2009-01-15 N-substituted indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/immuno-modulating action

Country Status (27)

Country Link
US (4) US6008231A (xx)
EP (1) EP0931063B3 (xx)
JP (1) JP3296437B2 (xx)
KR (1) KR100516321B1 (xx)
CN (3) CN100488948C (xx)
AR (1) AR008630A1 (xx)
AT (1) ATE342889T1 (xx)
AU (1) AU726521B2 (xx)
BR (1) BR9712808B1 (xx)
CA (1) CA2215013C (xx)
CZ (1) CZ302301B6 (xx)
DE (2) DE19636150A1 (xx)
DK (1) DK0931063T5 (xx)
ES (1) ES2276433T7 (xx)
HK (3) HK1021641A1 (xx)
HU (1) HU227797B1 (xx)
IL (1) IL127798A (xx)
NO (2) NO314725B3 (xx)
NZ (1) NZ334476A (xx)
PT (1) PT931063E (xx)
RU (1) RU2237661C2 (xx)
SK (1) SK285618B6 (xx)
TR (1) TR199900469T2 (xx)
TW (1) TW550256B (xx)
UA (1) UA60312C2 (xx)
WO (1) WO1998009946A1 (xx)
ZA (1) ZA977475B (xx)

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Also Published As

Publication number Publication date
EP0931063B3 (de) 2009-04-08
NO20030481D0 (no) 2003-01-30
AU4015897A (en) 1998-03-26
US6008231A (en) 1999-12-28
DE59712752D1 (de) 2006-11-30
ES2276433T3 (es) 2007-06-16
CN1227542A (zh) 1999-09-01
AR008630A1 (es) 2000-02-09
NO314725B3 (no) 2009-03-09
ZA977475B (en) 1998-02-19
SK27199A3 (en) 1999-08-06
US6344467B1 (en) 2002-02-05
TR199900469T2 (xx) 1999-05-21
HK1123280A1 (en) 2009-06-12
US20030207892A1 (en) 2003-11-06
KR20000068495A (ko) 2000-11-25
WO1998009946A1 (de) 1998-03-12
CN101219985A (zh) 2008-07-16
BR9712808B1 (pt) 2009-05-05
NO20030481L (no) 1999-03-04
CZ61699A3 (cs) 1999-06-16
AU726521B2 (en) 2000-11-09
KR100516321B1 (ko) 2005-09-23
NO314725B1 (no) 2003-05-12
NO991071D0 (no) 1999-03-04
AU726521C (en) 1998-03-26
CN1496980A (zh) 2004-05-19
BR9712808A (pt) 1999-11-23
CA2215013A1 (en) 1998-03-06
TW550256B (en) 2003-09-01
SK285618B6 (sk) 2007-05-03
JP2000505098A (ja) 2000-04-25
CN100376554C (zh) 2008-03-26
RU2237661C2 (ru) 2004-10-10
DE19636150A1 (de) 1998-03-12
DK0931063T5 (da) 2010-01-11
IL127798A (en) 2003-07-31
NZ334476A (en) 2000-05-26
US20020161025A1 (en) 2002-10-31
EP0931063A1 (de) 1999-07-28
HUP9903741A3 (en) 2001-01-29
IL127798A0 (en) 1999-10-28
CN101219985B (zh) 2011-04-27
CA2215013C (en) 2002-03-05
HK1064379A1 (en) 2005-01-28
ATE342889T1 (de) 2006-11-15
CZ302301B6 (cs) 2011-02-09
UA60312C2 (uk) 2003-10-15
PT931063E (pt) 2007-02-28
HUP9903741A2 (hu) 2000-04-28
US6919344B2 (en) 2005-07-19
ES2276433T7 (es) 2009-11-05
HU227797B1 (en) 2012-03-28
DK0931063T3 (da) 2007-02-19
NO991071L (no) 1999-03-04
JP3296437B2 (ja) 2002-07-02
EP0931063B1 (de) 2006-10-18
CN100488948C (zh) 2009-05-20

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