PL329351A1 - Piperidines and pyrolydines - Google Patents

Piperidines and pyrolydines

Info

Publication number
PL329351A1
PL329351A1 PL97329351A PL32935197A PL329351A1 PL 329351 A1 PL329351 A1 PL 329351A1 PL 97329351 A PL97329351 A PL 97329351A PL 32935197 A PL32935197 A PL 32935197A PL 329351 A1 PL329351 A1 PL 329351A1
Authority
PL
Poland
Prior art keywords
pyrolydines
piperidines
Prior art date
Application number
PL97329351A
Inventor
Joachim Maerz
Henning Boettcher
Ralf Devant
Hartmut Greiner
Gerd Bartoszyk
Juergen Harting
Christoph Seyfried
Ronny Andersson Bengt
Lars Olov Hansson
Clas Ake Sonesson
Nils Peter Stjernloef
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL329351A1 publication Critical patent/PL329351A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
PL97329351A 1996-04-18 1997-04-14 Piperidines and pyrolydines PL329351A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19615232A DE19615232A1 (en) 1996-04-18 1996-04-18 New carbamoyl derivatives and their use as 5-HT ¶1¶¶A¶ antagonists
PCT/EP1997/001853 WO1997040038A1 (en) 1996-04-18 1997-04-14 Piperidines and pyrrolidines

Publications (1)

Publication Number Publication Date
PL329351A1 true PL329351A1 (en) 1999-03-29

Family

ID=7791576

Family Applications (1)

Application Number Title Priority Date Filing Date
PL97329351A PL329351A1 (en) 1996-04-18 1997-04-14 Piperidines and pyrolydines

Country Status (15)

Country Link
EP (1) EP0898569A1 (en)
JP (1) JP2000508670A (en)
KR (1) KR20000005505A (en)
AR (1) AR006690A1 (en)
AU (1) AU2696797A (en)
BR (1) BR9708677A (en)
CA (1) CA2252385A1 (en)
CZ (1) CZ330598A3 (en)
DE (1) DE19615232A1 (en)
HU (1) HUP9901389A3 (en)
NO (1) NO984861D0 (en)
PL (1) PL329351A1 (en)
SK (1) SK141998A3 (en)
WO (1) WO1997040038A1 (en)
ZA (1) ZA973301B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19756036A1 (en) 1997-12-17 1999-06-24 Merck Patent Gmbh New indole amide derivatives
US6150533A (en) * 1998-04-08 2000-11-21 American Home Products Corp. N-aryloxyethyl-indoly-alkylamines for the treatment of depression
CN1135228C (en) * 1998-04-08 2004-01-21 惠氏公司 N-aryloxyethyl-indoly-alkylamines for treatment of depression
CN1307576A (en) * 1998-04-29 2001-08-08 美国家用产品公司 Serotongergic agents
US6376494B1 (en) 1998-06-15 2002-04-23 American Home Products Corporation Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents
JP2002518382A (en) * 1998-06-15 2002-06-25 アメリカン・ホーム・プロダクツ・コーポレイション Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonin agonists
EP1140830B1 (en) * 1998-12-17 2005-05-04 Wyeth Arylpiperidine and aryl-1,2,5,6-tetrahydropyridine amide derivatives having 5ht1a receptor activity
US6239126B1 (en) 1998-12-17 2001-05-29 American Home Products Corporation Arylpiperidine and aryl-1,2,5,6-tetra-hydropyridine urea derivatives
US6326381B1 (en) 1998-12-17 2001-12-04 American Home Products Corporation Arylpiperidine and aryl-1,2,5,6-tetrahydropyidine amide derivates
CN1335835A (en) * 1998-12-17 2002-02-13 美国家用产品公司 Arylpiperidine and aryl-1,2,5,6-tetrahydropyridine urea derivatives having 5HT1A receptor activity
WO2000044376A1 (en) * 1999-01-28 2000-08-03 Bristol-Myers Squibb Company Antidepressant heterocyclic compounds
EP1348019B9 (en) * 2000-12-27 2012-04-18 Axiogenesis Ag System for the cell-specific and development-specific selection of differentiating embryonic stem cells, adult stem cells and embryonic germline cells
KR100459917B1 (en) * 2001-12-14 2004-12-03 (주)바이오뉴트리젠 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising same
DE10337184A1 (en) * 2003-08-13 2005-03-10 Gruenenthal Gmbh Substituted 3-pyrrolidine-indole derivatives
JP2017538678A (en) 2014-11-05 2017-12-28 フレクサス・バイオサイエンシーズ・インコーポレイテッドFlexus Biosciences, Inc. Immunomodulator
UY36390A (en) * 2014-11-05 2016-06-01 Flexus Biosciences Inc MODULATING COMPOUNDS OF INDOLAMINE ENZYME 2,3-DIOXYGENASE (IDO), ITS SYNTHESIS METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
WO2023144764A1 (en) 2022-01-29 2023-08-03 Suven Life Sciences Limited Benzoisothiazole and benzoisoxazole compounds for the treatment of mental disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3226392A (en) * 1960-03-07 1965-12-28 Sterling Drug Inc 1-[n-aryl-n-acylaminoalkyl]-4-aryl-1,2,3,6-tetrahydropyridines, the corresponding piperidines and their salts
US3635982A (en) * 1969-04-08 1972-01-18 American Home Prod Amino-substituted-quinoxalinyloxazolidines and -oxazines
US4782071A (en) * 1986-11-03 1988-11-01 Warner-Lambert Company Tetrasubstituted urea cholinergic agents
MX9201991A (en) * 1991-05-02 1992-11-01 Jonh Wyeth & Brother Limited DERIVATIVES OF PIPERAZINE AND PROCEDURE FOR ITS PREPARATION.
FR2706894A1 (en) * 1993-06-22 1994-12-30 Synthelabo N-Phenyl-N-(piperidinoalkyl)arylamide derivatives, their preparation and their application in therapeutics
GB9314758D0 (en) * 1993-07-16 1993-08-25 Wyeth John & Brother Ltd Heterocyclic derivatives
EP0661266A1 (en) * 1993-12-27 1995-07-05 Toa Eiyo Ltd. Substituted cyclic amine compounds as 5HT2 antagonists
GB9411099D0 (en) * 1994-06-03 1994-07-27 Wyeth John & Brother Ltd Piperazine derivatives

Also Published As

Publication number Publication date
BR9708677A (en) 1999-08-03
NO984861L (en) 1998-10-16
HUP9901389A3 (en) 2000-09-28
JP2000508670A (en) 2000-07-11
HUP9901389A2 (en) 1999-08-30
AR006690A1 (en) 1999-09-08
EP0898569A1 (en) 1999-03-03
WO1997040038A1 (en) 1997-10-30
SK141998A3 (en) 1999-03-12
DE19615232A1 (en) 1997-10-23
CZ330598A3 (en) 1999-01-13
CA2252385A1 (en) 1997-10-30
NO984861D0 (en) 1998-10-16
AU2696797A (en) 1997-11-12
ZA973301B (en) 1997-10-24
KR20000005505A (en) 2000-01-25

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