HUP9901389A3 - Piperidine and pyrrolidine derivatives acting for the central nervous system, pharmaceutical compositions containing these compounds, preparation and use thereof - Google Patents
Piperidine and pyrrolidine derivatives acting for the central nervous system, pharmaceutical compositions containing these compounds, preparation and use thereofInfo
- Publication number
- HUP9901389A3 HUP9901389A3 HU9901389A HUP9901389A HUP9901389A3 HU P9901389 A3 HUP9901389 A3 HU P9901389A3 HU 9901389 A HU9901389 A HU 9901389A HU P9901389 A HUP9901389 A HU P9901389A HU P9901389 A3 HUP9901389 A3 HU P9901389A3
- Authority
- HU
- Hungary
- Prior art keywords
- piperidine
- compounds
- preparation
- pharmaceutical compositions
- nervous system
- Prior art date
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 2
- 210000003169 central nervous system Anatomy 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003235 pyrrolidines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19615232A DE19615232A1 (en) | 1996-04-18 | 1996-04-18 | New carbamoyl derivatives and their use as 5-HT ¶1¶¶A¶ antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9901389A2 HUP9901389A2 (en) | 1999-08-30 |
| HUP9901389A3 true HUP9901389A3 (en) | 2000-09-28 |
Family
ID=7791576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9901389A HUP9901389A3 (en) | 1996-04-18 | 1997-04-14 | Piperidine and pyrrolidine derivatives acting for the central nervous system, pharmaceutical compositions containing these compounds, preparation and use thereof |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0898569A1 (en) |
| JP (1) | JP2000508670A (en) |
| KR (1) | KR20000005505A (en) |
| AR (1) | AR006690A1 (en) |
| AU (1) | AU2696797A (en) |
| BR (1) | BR9708677A (en) |
| CA (1) | CA2252385A1 (en) |
| CZ (1) | CZ330598A3 (en) |
| DE (1) | DE19615232A1 (en) |
| HU (1) | HUP9901389A3 (en) |
| NO (1) | NO984861D0 (en) |
| PL (1) | PL329351A1 (en) |
| SK (1) | SK141998A3 (en) |
| WO (1) | WO1997040038A1 (en) |
| ZA (1) | ZA973301B (en) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19756036A1 (en) | 1997-12-17 | 1999-06-24 | Merck Patent Gmbh | New indole amide derivatives |
| CA2327513A1 (en) * | 1998-04-08 | 1999-10-14 | James Albert Nelson | N-aryloxyethyl-indoly-alkylamines for the treatment of depression |
| US6150533A (en) * | 1998-04-08 | 2000-11-21 | American Home Products Corp. | N-aryloxyethyl-indoly-alkylamines for the treatment of depression |
| AR015035A1 (en) * | 1998-04-29 | 2001-04-11 | American Home Prod | SEROTONERGIC AGENTS, PHARMACEUTICAL COMPOSITION THAT CONTAINS THEM AND ITS USE FOR THE MANUFACTURE OF A MEDICINAL PRODUCT |
| CN1312802A (en) * | 1998-06-15 | 2001-09-12 | 美国家用产品公司 | Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents |
| US6376494B1 (en) | 1998-06-15 | 2002-04-23 | American Home Products Corporation | Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents |
| AU3123500A (en) * | 1998-12-17 | 2000-07-03 | American Home Products Corporation | Arylpiperidine and aryl-1,2,5,6-tetrahydropyridine urea derivatives having 5ht1areceptor activity |
| CN1210261C (en) * | 1998-12-17 | 2005-07-13 | 惠氏公司 | Arylpiperidine and aryl-1,2,5,6-tetrahydropyridine amide derivatives having 5HT1A receptor activity |
| US6239126B1 (en) | 1998-12-17 | 2001-05-29 | American Home Products Corporation | Arylpiperidine and aryl-1,2,5,6-tetra-hydropyridine urea derivatives |
| US6326381B1 (en) | 1998-12-17 | 2001-12-04 | American Home Products Corporation | Arylpiperidine and aryl-1,2,5,6-tetrahydropyidine amide derivates |
| TR200101939T2 (en) * | 1999-01-28 | 2002-05-21 | Bristol-Myers Squibb Company | Antidepressant heterocyclic compounds |
| US20040096432A1 (en) * | 2000-12-27 | 2004-05-20 | Bernd Fleischmann | System for the cell-specific and development-specific selection of differentiating embryonic stem cells, adult stem cells and embryonic germline cells |
| KR100459917B1 (en) * | 2001-12-14 | 2004-12-03 | (주)바이오뉴트리젠 | Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising same |
| DE10337184A1 (en) * | 2003-08-13 | 2005-03-10 | Gruenenthal Gmbh | Substituted 3-pyrrolidine-indole derivatives |
| UY36390A (en) * | 2014-11-05 | 2016-06-01 | Flexus Biosciences Inc | MODULATING COMPOUNDS OF INDOLAMINE ENZYME 2,3-DIOXYGENASE (IDO), ITS SYNTHESIS METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| EP3215141A4 (en) | 2014-11-05 | 2018-06-06 | Flexus Biosciences, Inc. | Immunoregulatory agents |
| CN118647615A (en) | 2022-01-29 | 2024-09-13 | 苏文生命科学有限公司 | Benzisothiazole and benzisoxazole compounds for the treatment of psychotic disorders |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3226392A (en) * | 1960-03-07 | 1965-12-28 | Sterling Drug Inc | 1-[n-aryl-n-acylaminoalkyl]-4-aryl-1,2,3,6-tetrahydropyridines, the corresponding piperidines and their salts |
| US3647790A (en) * | 1969-04-08 | 1972-03-07 | American Home Prod | Ouinoxalinyl-oxazolidines and -oxazines |
| US4782071A (en) * | 1986-11-03 | 1988-11-01 | Warner-Lambert Company | Tetrasubstituted urea cholinergic agents |
| MX9201991A (en) * | 1991-05-02 | 1992-11-01 | Jonh Wyeth & Brother Limited | DERIVATIVES OF PIPERAZINE AND PROCEDURE FOR ITS PREPARATION. |
| FR2706894A1 (en) * | 1993-06-22 | 1994-12-30 | Synthelabo | N-Phenyl-N-(piperidinoalkyl)arylamide derivatives, their preparation and their application in therapeutics |
| GB9314758D0 (en) * | 1993-07-16 | 1993-08-25 | Wyeth John & Brother Ltd | Heterocyclic derivatives |
| EP0661266A1 (en) * | 1993-12-27 | 1995-07-05 | Toa Eiyo Ltd. | Substituted cyclic amine compounds as 5HT2 antagonists |
| GB9411099D0 (en) * | 1994-06-03 | 1994-07-27 | Wyeth John & Brother Ltd | Piperazine derivatives |
-
1996
- 1996-04-18 DE DE19615232A patent/DE19615232A1/en not_active Withdrawn
-
1997
- 1997-04-14 PL PL97329351A patent/PL329351A1/en unknown
- 1997-04-14 CZ CZ983305A patent/CZ330598A3/en unknown
- 1997-04-14 SK SK1419-98A patent/SK141998A3/en unknown
- 1997-04-14 KR KR1019980708295A patent/KR20000005505A/en not_active Application Discontinuation
- 1997-04-14 HU HU9901389A patent/HUP9901389A3/en unknown
- 1997-04-14 AU AU26967/97A patent/AU2696797A/en not_active Abandoned
- 1997-04-14 JP JP9537685A patent/JP2000508670A/en active Pending
- 1997-04-14 WO PCT/EP1997/001853 patent/WO1997040038A1/en not_active Application Discontinuation
- 1997-04-14 CA CA002252385A patent/CA2252385A1/en not_active Abandoned
- 1997-04-14 BR BR9708677A patent/BR9708677A/en not_active Application Discontinuation
- 1997-04-14 EP EP97920673A patent/EP0898569A1/en not_active Withdrawn
- 1997-04-17 ZA ZA9703301A patent/ZA973301B/en unknown
- 1997-04-18 AR ARP970101562A patent/AR006690A1/en unknown
-
1998
- 1998-10-16 NO NO984861A patent/NO984861D0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2252385A1 (en) | 1997-10-30 |
| HUP9901389A2 (en) | 1999-08-30 |
| ZA973301B (en) | 1997-10-24 |
| DE19615232A1 (en) | 1997-10-23 |
| BR9708677A (en) | 1999-08-03 |
| JP2000508670A (en) | 2000-07-11 |
| NO984861L (en) | 1998-10-16 |
| KR20000005505A (en) | 2000-01-25 |
| AU2696797A (en) | 1997-11-12 |
| NO984861D0 (en) | 1998-10-16 |
| WO1997040038A1 (en) | 1997-10-30 |
| AR006690A1 (en) | 1999-09-08 |
| EP0898569A1 (en) | 1999-03-03 |
| PL329351A1 (en) | 1999-03-29 |
| SK141998A3 (en) | 1999-03-12 |
| CZ330598A3 (en) | 1999-01-13 |
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