IL113103A0 - Piperidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents

Piperidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same

Info

Publication number
IL113103A0
IL113103A0 IL11310395A IL11310395A IL113103A0 IL 113103 A0 IL113103 A0 IL 113103A0 IL 11310395 A IL11310395 A IL 11310395A IL 11310395 A IL11310395 A IL 11310395A IL 113103 A0 IL113103 A0 IL 113103A0
Authority
IL
Israel
Prior art keywords
processes
preparation
same
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL11310395A
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL113103A0 publication Critical patent/IL113103A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
IL11310395A 1994-03-24 1995-03-23 Piperidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same IL113103A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4410822A DE4410822A1 (en) 1994-03-24 1994-03-24 New piperidine derivatives

Publications (1)

Publication Number Publication Date
IL113103A0 true IL113103A0 (en) 1995-06-29

Family

ID=6514110

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11310395A IL113103A0 (en) 1994-03-24 1995-03-23 Piperidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same

Country Status (16)

Country Link
EP (1) EP0751936A1 (en)
JP (1) JPH09510460A (en)
KR (1) KR970701695A (en)
CN (1) CN1145618A (en)
AU (1) AU2212595A (en)
CA (1) CA2186010A1 (en)
CZ (1) CZ277096A3 (en)
DE (1) DE4410822A1 (en)
FI (1) FI963786A0 (en)
HU (1) HUT75653A (en)
IL (1) IL113103A0 (en)
NO (1) NO963984L (en)
PL (1) PL316382A1 (en)
SK (1) SK120196A3 (en)
WO (1) WO1995025721A1 (en)
ZA (1) ZA952431B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
ZA9610736B (en) 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ATE216883T1 (en) * 1996-03-08 2002-05-15 Hoffmann La Roche USE OF 4-PHENYL-3,6-DIHYDRO-2H-PYRIDYL DERIVATIVES AS NMDA RECEPTOR SUBTYPE BLOCKERS
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
PL332413A1 (en) 1996-09-27 1999-09-13 Guilford Pharm Inc Compositions containing inhibitors of naaladase as well as methods of treating glutamatic anomaly and influencing neuronic functions among animals
US6242450B1 (en) * 1998-07-27 2001-06-05 Eli Lilly And Company 5-HT1F antagonists
JP2002521444A (en) * 1998-07-31 2002-07-16 イーライ・リリー・アンド・カンパニー Heterocyclic sulfonamide derivatives
KR20020002501A (en) * 1999-05-13 2002-01-09 시오노 요시히코 Preventive or therapeutic drugs for diabetes
TWI254043B (en) * 1999-06-08 2006-05-01 Hoffmann La Roche Ethanesulfonyl-piperidine derivatives having good affinity to N-methyl-D-aspartate (NMDA) receptor
ES2225330T3 (en) 2000-03-22 2005-03-16 Hoffmann La Roche PIPERIDINE AND PIPERACINE COMPOSITE FOR USE IN THE TREATMENT OF ALZHEIMER.
US6407235B1 (en) 2000-08-21 2002-06-18 Hoffmann-La Roche Inc. Prodrug acid esters of [2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethansulfonyl]phenol
US6770659B2 (en) * 2002-08-26 2004-08-03 Sk Corporation Benzoyl piperidine compounds
GB0224084D0 (en) 2002-10-16 2002-11-27 Glaxo Group Ltd Novel compounds
EP3641769B1 (en) 2017-06-20 2022-06-08 Imbria Pharmaceuticals, Inc. 1-[(2,3,4-trimethoxyphenyl)methyl]-piperazine derivative, compositions thereof and methods for increasing efficiency of cardiac metabolism
CN110437136A (en) * 2019-07-30 2019-11-12 东南大学 1- virtue oxygen ethyl piperidine -4- base methanone derivatives and its preparation method and application
US11780811B2 (en) 2020-06-30 2023-10-10 Imbria Pharmaceuticals, Inc. Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11530184B2 (en) 2020-06-30 2022-12-20 Imbria Pharmaceuticals, Inc. Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11883396B2 (en) 2021-05-03 2024-01-30 Imbria Pharmaceuticals, Inc. Methods of treating kidney conditions using modified forms of trimetazidine

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3576810A (en) * 1968-06-20 1971-04-27 Robins Co Inc A H 1-substituted-3-(-4)-aroylpiperidines
DE2827566A1 (en) * 1978-06-23 1980-01-10 Boehringer Mannheim Gmbh 1,2-DIHYDRO-CHINOLIN-2-ON DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
WO1982003861A1 (en) * 1981-05-08 1982-11-11 Tominaga Michiaki Aniline derivatives,process for their preparation,and cardiotonics
PH19166A (en) * 1982-09-04 1986-01-16 Pfizer Dihydropyridined,pharmaceutical compositions and method of use
FR2534580A1 (en) * 1982-10-13 1984-04-20 Synthelabo PHENYL-1 PIPERIDINO-2 PROPANOL DERIVATIVES, THEIR PREPARATION, AND MEDICINES THAT CONTAIN THEM
DK623586A (en) * 1985-12-27 1987-06-28 Eisai Co Ltd PIPERIDE INGREDIENTS OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS
US4868181A (en) * 1986-08-04 1989-09-19 E. I. Du Pont De Nemours And Company 1,4-dihydropyridine derivatives with calcium agonist and alpha1 -antagonist activity
KR910006138B1 (en) * 1986-09-30 1991-08-16 에자이 가부시끼가이샤 Cyclic amine derivatives
EP0294183B1 (en) * 1987-06-02 1994-03-30 Ajinomoto Co., Inc. Use of ethylamine derivatives as antihypertensive agents
WO1989005289A1 (en) * 1987-12-11 1989-06-15 Mitsui Petrochemical Industries, Ltd. Novel amines and their use
SU1731048A3 (en) * 1988-05-27 1992-04-30 Эйсай Ко., Лтд (Фирма) Process for preparing piperidine derivatives of pharmacolocically acceptable salts thereof
FR2632641B1 (en) * 1988-06-13 1990-10-12 Irceba ((ARYL-4-PIPERAZINYL-1) -2 ETHOXY) -3 P-CYMENE, ORTHO DERIVATIVES, META, PARA MONOSUBSTITUTED OR DISUBSTITUTED ON THE PHENYL CORE OF THIS PRODUCT, THE PROCESS FOR THE PREPARATION OF SUCH DERIVATIVES, AND THE MEDICINAL PRODUCTS AS ACTIVE PRINCIPLE
US5153198A (en) * 1989-03-15 1992-10-06 Santen Pharmaceutical Co., Ltd. Agent for treatment of disorders of the cerebro-neural transmission system
US5116846A (en) * 1990-03-28 1992-05-26 Du Pont Merck Pharmaceutical Company N-aralkyl piperidine derivatives as psychotropic drugs
FR2681319B1 (en) * 1991-09-12 1995-02-17 Synthelabo 1- (PHENOXYALKYL) PIPERIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
ES2060547B1 (en) * 1992-06-04 1995-06-16 Ferrer Int IMPROVEMENTS IN THE PURPOSE OF THE INVENTION PATENT N / 9201158 THAT REFERS TO "PROCEDURE FOR OBTAINING NEW DERIVATIVES OF 4-BENCILPIPERIDINE".
FR2705343B1 (en) * 1993-05-17 1995-07-21 Fournier Ind & Sante Beta, beta-dimethyl-4-piperidineethanamine derivatives, process for their preparation and their use in therapy.

Also Published As

Publication number Publication date
FI963786A (en) 1996-09-23
PL316382A1 (en) 1997-01-06
MX9604201A (en) 1997-12-31
CZ277096A3 (en) 1997-01-15
JPH09510460A (en) 1997-10-21
AU2212595A (en) 1995-10-09
KR970701695A (en) 1997-04-12
HUT75653A (en) 1997-05-28
HU9602607D0 (en) 1996-11-28
DE4410822A1 (en) 1995-09-28
CA2186010A1 (en) 1995-09-28
SK120196A3 (en) 1997-10-08
WO1995025721A1 (en) 1995-09-28
EP0751936A1 (en) 1997-01-08
NO963984D0 (en) 1996-09-23
NO963984L (en) 1996-09-23
FI963786A0 (en) 1996-09-23
CN1145618A (en) 1997-03-19
ZA952431B (en) 1995-12-19

Similar Documents

Publication Publication Date Title
HUP9902471A3 (en) Piperazine and piperidine compounds, process for their preparation and pharmaceutical compositions containing the same
IL135920A0 (en) 2-aryl -8-oxodihydropurine derivative, process for the preparation thereof, pharmaceutical composition containing the same and intermediate therefor
HUT73772A (en) Novel erythromycin derivatives, method for preparing same and pharmaceutical compositions containing the same
HUP9900974A3 (en) Heterocycle-condensed morphinoid derivatives, process for the preparation thereof, their use and pharmaceutical compositions containing them
IL112193A0 (en) Phenylpyrazolopyridine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
HUP0001508A3 (en) 4-arylmethylene-2-imino-2,3-dihydrothiazole derivatives, their use, process for the preparation thereof and pharmaceutical compositions containing them
IL118369A0 (en) Piperazine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
IL108873A0 (en) 2-debenzoyl-2-acyl taxol derivatives, pharmaceutical compositions containing the same, and methods for the preparation thereof
HUP9602122A3 (en) Camptothecin derivatives, process for the preparation thereof and pharmaceutical compositions containing them
HUP9603495A3 (en) 1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol-compounds, pharmaceutical compositions containing the same and process for their preparation
HUT74464A (en) 1n-alkyl-n-arylpyrimidinamines and derivatives thereof, and pharmaceutical compositions containing them
IL116917A0 (en) Piperidine derivatives and pharmaceutical compositions containing the same
IL111002A0 (en) Piperidine derivatives, their preparation and pharmaceutical compositions containing them
IL115039A (en) Spiroazabicyclic compounds, their preparation and pharmaceutical compositions containing them
IL111533A0 (en) Quinoxalinedione derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same
IL113103A0 (en) Piperidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
HUP9701194A3 (en) 4-hydroxy-piperidine derivatives, preparation and use thereof, pharmaceutical compositions containing these compounds
IL99030A0 (en) 1,4-dihydropyridine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
HUP0102215A3 (en) Benzoylpyridazines, pharmaceutical compositions containing the same and process for their preparation
IL112443A0 (en) Heterocyclic compounds, their preparation and pharmaceutical compositions containing them
IL92425A0 (en) Alpha-d-glucofuranose derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof
HUP9901485A2 (en) Heterocyclylcarboxamide derivatives, pharmaceutical compositions containing the same, process for their preparation and their use
HUP9801386A3 (en) Indazolecarboxamide derivatives, preparation thereof and pharmaceutical compositions containing them
IL107358A0 (en) a-Phosphonosulfonate derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
GB9123353D0 (en) New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same