HK1020194A1 - Crystals of benzimidazole derivatives and their production - Google Patents

Crystals of benzimidazole derivatives and their production

Info

Publication number
HK1020194A1
HK1020194A1 HK99105122A HK99105122A HK1020194A1 HK 1020194 A1 HK1020194 A1 HK 1020194A1 HK 99105122 A HK99105122 A HK 99105122A HK 99105122 A HK99105122 A HK 99105122A HK 1020194 A1 HK1020194 A1 HK 1020194A1
Authority
HK
Hong Kong
Prior art keywords
substituted
optionally
crystals
production
benzimidazole derivatives
Prior art date
Application number
HK99105122A
Other languages
English (en)
Inventor
Masayasu Kato
Toru Ishida
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17920069&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1020194(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of HK1020194A1 publication Critical patent/HK1020194A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK99105122A 1996-11-14 1999-11-09 Crystals of benzimidazole derivatives and their production HK1020194A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP30336196 1996-11-14
PCT/JP1997/004136 WO1998021201A1 (en) 1996-11-14 1997-11-13 Crystals of benzimidazole derivatives and their production

Publications (1)

Publication Number Publication Date
HK1020194A1 true HK1020194A1 (en) 2000-03-31

Family

ID=17920069

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99105122A HK1020194A1 (en) 1996-11-14 1999-11-09 Crystals of benzimidazole derivatives and their production

Country Status (19)

Country Link
US (1) US6002011A (es)
EP (1) EP0944617B1 (es)
KR (1) KR100519576B1 (es)
CN (2) CN100355749C (es)
AT (1) ATE240314T1 (es)
AU (1) AU731776B2 (es)
CA (1) CA2269053C (es)
DE (1) DE69722027T2 (es)
DK (1) DK0944617T3 (es)
ES (1) ES2199356T3 (es)
HK (1) HK1020194A1 (es)
ID (1) ID21547A (es)
IL (1) IL129724A (es)
NZ (1) NZ335145A (es)
PT (1) PT944617E (es)
TR (1) TR199901055T2 (es)
TW (1) TW385306B (es)
WO (1) WO1998021201A1 (es)
ZA (1) ZA9710255B (es)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW385306B (en) * 1996-11-14 2000-03-21 Takeda Chemical Industries Ltd Method for producing crystals of benzimidazole derivatives
IL142703A (en) 1998-11-10 2006-04-10 Astrazeneca Ab Crystalline form of omeprazole
UA72748C2 (en) 1998-11-10 2005-04-15 Astrazeneca Ab A novel crystalline form of omeprazole
JP3926936B2 (ja) 1998-11-16 2007-06-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホキシド誘導体・アセトン錯体およびその製造法
DE50012015D1 (de) * 1999-02-04 2006-03-30 Joern Bullerdiek Mittel zur prävention und/oder behandlung einer gewebeveränderung mesenchymalen ursprungs
TWI275587B (en) 1999-06-17 2007-03-11 Takeda Chemical Industries Ltd A crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
PL333847A1 (en) * 1999-06-18 2001-01-02 Inst Farmaceutyczny Crystalline forms of lansoprozole and method of obtaining lansoprazole in pharmacologically advanthageous crystalline form
PT1191025E (pt) 1999-06-30 2005-09-30 Takeda Pharmaceutical Cristais de lansoprazol
ES2511774T3 (es) 2000-05-15 2014-10-23 Takeda Pharmaceutical Company Limited Formas cristalinas de (R)-lansoprazol
WO2002012225A1 (fr) * 2000-08-04 2002-02-14 Takeda Chemical Industries, Ltd. Sels de composé à base de benzimidazole et leurs applications
WO2002015908A1 (fr) 2000-08-18 2002-02-28 Takeda Chemical Industries, Ltd. Injections
DK1337525T3 (da) 2000-12-01 2011-09-19 Takeda Pharmaceutical Fremgangsmåde til krystallisering af (R)- eller (S)-lansoprazol
DE10140492A1 (de) 2001-08-17 2003-08-14 Gruenenthal Gmbh Hydrate von gegebenenfalls substituierten 2-(2-Pyridinyl)methylthio-1H-benzimidazolen und Verfahren zu ihrer Herstellung
WO2003032953A1 (fr) 2001-10-17 2003-04-24 Takeda Chemical Industries, Ltd. Granules contenant un agent chimique instable en milieu acide, en concentration elevee
KR20090045420A (ko) * 2002-02-19 2009-05-07 테바 파마슈티컬 인더스트리즈 리미티드 아토르바스타틴 헤미-칼슘 용매화합물의 탈용매화
US20040010151A1 (en) * 2002-03-27 2004-01-15 Nina Finkelstein Lansoprazole polymorphs and processes for preparation thereof
KR100873419B1 (ko) * 2002-06-18 2008-12-11 페어차일드코리아반도체 주식회사 높은 항복 전압, 낮은 온 저항 및 작은 스위칭 손실을갖는 전력용 반도체 소자
TW200410955A (en) 2002-07-29 2004-07-01 Altana Pharma Ag Novel salt of (S)-PANTOPRAZOLE
US6909004B2 (en) * 2002-08-21 2005-06-21 Teva Pharmaceutical Industries Ltd. Method for the purification of lansoprazole
EP1764364A1 (en) * 2002-08-21 2007-03-21 Teva Pharmaceutical Industries Ltd A method for the purification of lansoprazole
EP1552833B1 (en) 2002-10-16 2016-12-28 Takeda Pharmaceutical Company Limited Process for producing an amorphous optically active isomer of lansoprazole
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
PT1465890E (pt) * 2002-11-18 2007-05-31 Teva Pharma Lansoprazole estável contendo mais de 500 ppm, até cerca de 3000 ppm de água e mais de 200 ppm, até cerca de 5000 de álcool
EP1743893A1 (en) 2002-11-18 2007-01-17 Teva Pharmaceutical Industries Ltd. Stable lansoprazole containing more than 500 ppm, up to about 3,000 ppm water and more than 200 ppm, up to about 5,000 ppm alcohol
CA2515130A1 (en) * 2003-02-05 2004-08-26 Teva Pharmaceutical Industries Ltd. Method of stabilizing lansoprazole
US7005732B2 (en) * 2003-10-21 2006-02-28 Honeywell International Inc. Methods and systems for providing MEMS devices with a top cap and upper sense plate
TW200526268A (en) * 2003-12-17 2005-08-16 Takeda Pharmaceutical Injectable composition
SE0400410D0 (sv) * 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
US8461187B2 (en) 2004-06-16 2013-06-11 Takeda Pharmaceuticals U.S.A., Inc. Multiple PPI dosage form
CA2787378C (en) * 2004-09-13 2015-11-03 Takeda Pharmaceutical Company Limited Method for producing lansoprazole crystal
EP1681056A1 (en) * 2005-01-14 2006-07-19 Krka Tovarna Zdravil, D.D., Novo Mesto Process for preparing lansoprazole
JP5124267B2 (ja) 2005-02-25 2013-01-23 武田薬品工業株式会社 顆粒の製造方法
EP1889841A4 (en) * 2005-06-07 2010-04-07 Takeda Pharmaceutical CRYSTAL OF A SALT OF A BENZIMIDAZOLE COMPOUND
WO2006134877A1 (ja) * 2005-06-13 2006-12-21 Takeda Pharmaceutical Company Limited 注射剤
KR20080081071A (ko) 2005-12-28 2008-09-05 다케다 야쿠힌 고교 가부시키가이샤 방출 제어 고형 제제
KR100758600B1 (ko) * 2006-01-05 2007-09-13 주식회사 대웅제약 란소프라졸 결정형 ａ의 제조방법
WO2008035189A1 (en) * 2006-09-22 2008-03-27 Orchid Chemicals & Pharmaceuticals Limited A method for the purification of lansoprazole
US20100093804A1 (en) * 2006-12-07 2010-04-15 Hetero Drugs Limited novel crystalline form of lansoprazole
ITMI20062481A1 (it) * 2006-12-22 2008-06-23 Recordati Chem Pharm Processo per la preparazione di lansoprazolo forma i microcristallino
EP2098250B1 (en) 2006-12-28 2016-09-28 Takeda Pharmaceutical Company Limited Orally disintegrating solid preparation
WO2009088857A1 (en) * 2007-12-31 2009-07-16 Takeda Pharmaceutical Company Limited Crystalline solvated forms of (r) -2- [ [ [3-methyl-4- (2, 2, 2-trifluoroethoxy) -2-pyridinyl] methyl] sulfinyl] -1h-benz imidazole
CL2009000547A1 (es) * 2008-03-10 2010-05-07 Takeda Pharmaceuticals Co Forma cristalina de (r)-2[[[3-metil-4-(2,2,2-trifluoroetoxi)-2-piridinil]metil]sulfinil]-1h-bencimidazol, metodo de preparacion; composicion farmaceutica y su uso para la profilaxis o tratamiento de ulcera peptica, gastritis, esofagitis erosiva, esofago de barret,dispepsia funcional, cancer gastrico.
WO2011004387A2 (en) 2009-06-18 2011-01-13 Matrix Laboratories Ltd Process for the preparation of dexlansoprazole polymorphic forms
US20130012714A1 (en) * 2010-02-11 2013-01-10 Orchid Chemicals & Pharmaceuticals Limited Novel solvate of dexlansoprazole
EP2647381A4 (en) 2010-12-03 2015-12-23 Takeda Pharmaceutical MELTING TABLET
CN103402500A (zh) 2010-12-27 2013-11-20 武田药品工业株式会社 口腔崩解片剂
CN102180866B (zh) * 2011-05-23 2013-03-13 中山大学 兰索拉唑晶型及其制备方法和应用
CN103012369B (zh) * 2011-05-23 2014-04-23 中山大学 兰索拉唑n晶型及其制备方法和应用
AR089032A1 (es) 2011-11-30 2014-07-23 Takeda Pharmaceutical Comprimido recubierto seco
US9119769B2 (en) 2011-12-30 2015-09-01 The Curators Of The University Of Missouri Method for transforming pharmaceutical crystal forms
JP6364406B2 (ja) 2013-05-21 2018-07-25 武田薬品工業株式会社 口腔内崩壊錠
CN103539729A (zh) * 2013-10-14 2014-01-29 安徽国星生物化学有限公司 一种氯甲基吡啶衍生物的工业化生产方法
CN103539728A (zh) * 2013-10-14 2014-01-29 安徽国星生物化学有限公司 一种拉唑类药物中间体氯甲基吡啶衍生物的合成方法
CN104829594A (zh) * 2015-05-15 2015-08-12 苗怡文 一种治疗胃溃疡的药物兰索拉唑化合物
CN104817492B (zh) * 2015-05-22 2018-05-18 抚州三和医药化工有限公司 兰索拉唑中间体2-羟甲基-3-甲基-4-(2,2,2-三氟乙氧基）吡啶的分离纯化方法
KR102649498B1 (ko) 2023-12-06 2024-03-20 거산해운(주) 선사별 실시간 통합 예약 정보를 기반으로 한 화주의 해상 운송 예약 자동화 플랫폼 서비스 제공 방법, 장치 및 시스템

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
DK171989B1 (da) * 1987-08-04 1997-09-08 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler
DE4018642C2 (de) * 1990-06-11 1993-11-25 Byk Gulden Lomberg Chem Fab Neue Salzform des 5-Difluormethoxy-2-[(3,4-dimethoxy-2-pyridyl) methylsulfinyl]-1H-benzimitazol-Natriumsalzes
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
SE9302395D0 (sv) * 1993-07-09 1993-07-09 Ab Astra New pharmaceutical formulation
US5374730A (en) * 1993-11-04 1994-12-20 Torcan Chemical Ltd. Preparation of omeprazole and lansoprazole
GB2297550B (en) * 1995-02-06 1997-04-09 Smithkline Beecham Plc Paroxetine hydrochloride anhydrate substantially free of bound organic solvent
TW385306B (en) * 1996-11-14 2000-03-21 Takeda Chemical Industries Ltd Method for producing crystals of benzimidazole derivatives

Also Published As

Publication number Publication date
IL129724A0 (en) 2000-02-29
AU731776B2 (en) 2001-04-05
AU4965297A (en) 1998-06-03
ZA9710255B (en) 1999-05-13
ID21547A (id) 1999-06-24
EP0944617A1 (en) 1999-09-29
CA2269053A1 (en) 1998-05-22
CN1171885C (zh) 2004-10-20
KR20000053158A (ko) 2000-08-25
NZ335145A (en) 2000-12-22
DE69722027T2 (de) 2004-03-25
ATE240314T1 (de) 2003-05-15
EP0944617B1 (en) 2003-05-14
CA2269053C (en) 2006-07-18
CN100355749C (zh) 2007-12-19
CN1237167A (zh) 1999-12-01
TW385306B (en) 2000-03-21
ES2199356T3 (es) 2004-02-16
WO1998021201A1 (en) 1998-05-22
CN1616457A (zh) 2005-05-18
IL129724A (en) 2004-02-19
DE69722027D1 (de) 2003-06-18
US6002011A (en) 1999-12-14
TR199901055T2 (xx) 1999-07-21
KR100519576B1 (ko) 2005-10-07
PT944617E (pt) 2003-08-29
DK0944617T3 (da) 2003-09-01

Similar Documents

Publication Publication Date Title
HK1020194A1 (en) Crystals of benzimidazole derivatives and their production
HUP9802859A2 (hu) Acil-amino-szalicilsav-amid-származékok és alkalmazásuk peszticidként
DE69534975D1 (de) Verwendung von noribogain derivaten zur behandlung von chemischer abhängigkeit bei säugern
ES8202546A1 (es) Metodo de producir derivados de tiazolidina
NZ329374A (en) Tricyclic amide and urea derivatives, preparation thereof
HK1023987A1 (en) Sulphinic acid derivatives, method for producing, and their use
TW368501B (en) 7-(2-aminoethyl)-benzothiazolones
ES8704445A1 (es) Procedimiento de preparar derivados aminicos
GB2091723B (en) Derivatives of 2-oxoazetidine-1-sulphonic acid
IE872588L (en) Compounds
ES8505518A1 (es) Procedimiento para preparar derivados de aminoacidos
MY109628A (en) An improved proces for the preparation of substituted indoline derivatives
RU1833371C (ru) Cпocoб пoлучehия amидoпpoизboдhыx 4-фehил-3-буtehoboй kиcлotы
EA200000484A1 (ru) Способ получения производных тиазолидиндиона
ES8507536A1 (es) Un procedimiento para la preparacion de estimulantes cardiacos de quinazolinas.
CY2257B1 (en) Process for preparing galanthamine derivatives by asymmetric reduction
PT99280A (pt) Processo de preparacao de derivados do indolo e de composicoes farmaceuticas
HU905000D0 (en) Process for producing compounds suitable for treatment of gastric ulcer
AR246321A1 (es) Nuevos colorantes y procedimiento para su obtencion.
HUP0003024A2 (hu) Eljárás nitro-guanidin-származékok előállítására és az új kiindulási vegyületek
GR3002688T3 (en) Thiadiazolylacetamide derivatives, process for the preparation thereof and their use
HUT39173A (en) Process for production of derivatives of 3-hydro-amino-2,3-dihydro-benzoxepin
ES8704175A1 (es) Un procedimiento para la preparacion de derivados de benzopirano (2,3-d) triazol.
EP0297560A3 (en) Imides; a process for their production and a process for the production of dipeptides using them
FR2794122B1 (fr) Nouveaux antioxydants, procedes de preparation et utilisations

Legal Events

Date Code Title Description
PF Patent in force
CHPA Change of a particular in the register (except of change of ownership)
PE Patent expired

Effective date: 20171112