HK1000785A1 - Oxygen-containing heterocyclic compounds - Google Patents
Oxygen-containing heterocyclic compoundsInfo
- Publication number
- HK1000785A1 HK1000785A1 HK97102285A HK97102285A HK1000785A1 HK 1000785 A1 HK1000785 A1 HK 1000785A1 HK 97102285 A HK97102285 A HK 97102285A HK 97102285 A HK97102285 A HK 97102285A HK 1000785 A1 HK1000785 A1 HK 1000785A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- bond
- oxygen
- containing heterocyclic
- cyano
- combined
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12153795 | 1995-05-19 | ||
| JP25865195 | 1995-10-05 | ||
| PCT/JP1996/001327 WO1996036624A1 (fr) | 1995-05-19 | 1996-05-20 | Composes heterocycliques contenant de l'oxygene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1000785A1 true HK1000785A1 (en) | 2006-06-30 |
Family
ID=26458881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK97102285A HK1000785A1 (en) | 1995-05-19 | 1997-11-28 | Oxygen-containing heterocyclic compounds |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0771794B1 (zh) |
| JP (1) | JP4172817B2 (zh) |
| KR (1) | KR100445356B1 (zh) |
| CN (1) | CN1163493C (zh) |
| AT (1) | ATE325110T1 (zh) |
| AU (1) | AU705690B2 (zh) |
| CA (1) | CA2195755A1 (zh) |
| DE (1) | DE69636086T2 (zh) |
| DK (1) | DK0771794T3 (zh) |
| ES (1) | ES2258775T3 (zh) |
| HK (1) | HK1000785A1 (zh) |
| NO (1) | NO317631B1 (zh) |
| PT (1) | PT771794E (zh) |
| WO (1) | WO1996036624A1 (zh) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5902824A (en) * | 1995-05-18 | 1999-05-11 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Phenyldihydrobenzofuranes |
| WO1996036626A1 (de) * | 1995-05-18 | 1996-11-21 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Cyclohexyldihydrobenzofurane |
| JP2000501411A (ja) * | 1995-12-05 | 2000-02-08 | ダーウィン・ディスカバリー・リミテッド | ベンゾフランカルボキサミドおよびスルホンアミド |
| IL126558A (en) * | 1996-05-20 | 2002-07-25 | Darwin Discovery Ltd | Benzofuran carboxamides and pharmaceutical compositions containing them |
| EP0923568B9 (en) * | 1996-08-19 | 2003-08-13 | ALTANA Pharma AG | Novel benzofuran-4-carboxamides |
| CA2272327A1 (en) * | 1996-11-19 | 1998-05-28 | Kyowa Hakko Kogyo Co., Ltd. | Oxygen-containing heterocyclic compounds |
| ATE237612T1 (de) * | 1997-10-01 | 2003-05-15 | Kyowa Hakko Kogyo Kk | Benzofuranderivate |
| CN1290266A (zh) * | 1998-02-09 | 2001-04-04 | 达尔文发现有限公司 | 苯并呋喃－4－甲酰胺和其治疗用途 |
| PT1095040E (pt) * | 1998-07-06 | 2004-08-31 | Altana Pharma Ag | Novos benzoxazoles com actividade inibidora da pde |
| CA2341890C (en) | 1998-09-03 | 2006-07-18 | Kyowa Hakko Kogyo Co., Ltd. | Oxygen-containing heterocyclic compounds |
| WO2000040714A2 (en) * | 1998-12-30 | 2000-07-13 | Oligos Etc. Inc. | Therapeutic phosphodiesterase inhibitors |
| WO2001007031A1 (fr) * | 1999-07-26 | 2001-02-01 | Shionogi & Co., Ltd. | Derives de benzene, compositions immunostimulantes ou agents de retablissement de la pharmacosensibilite les contenant |
| WO2003000697A1 (fr) * | 2001-06-22 | 2003-01-03 | Takeda Chemical Industries, Ltd. | Derive de furo-isoquinoline, procede de production de ce compose et utilisation de ce compose |
| DE10205274A1 (de) * | 2002-02-08 | 2003-08-21 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen enthaltend neben Anticholinergika heterocyclische Verbindungen |
| DE10216427A1 (de) * | 2002-04-12 | 2003-10-23 | Boehringer Ingelheim Pharma | Arzneimittelkompositionen enthaltend heterocyclische Verbindungen und ein neues Anticholinergikum |
| EP1535920A4 (en) * | 2002-07-03 | 2007-03-21 | Kyowa Hakko Kogyo Kk | PROCESS FOR THE PREPARATION OF 1,3-BENZODIOXOLE-2-SPIRO-CYCLOALCAN DERIVATIVES |
| RU2005131943A (ru) * | 2003-03-17 | 2006-03-20 | Киова Хакко Когио Ко., Лтд. (Jp) | Лечебные и/или профилактические средства для хронических болезней кожи |
| WO2004087150A1 (ja) * | 2003-03-31 | 2004-10-14 | Kyowa Hakko Kogyo Co. Ltd. | 医薬組成物 |
| JPWO2004087148A1 (ja) * | 2003-03-31 | 2006-06-29 | 協和醗酵工業株式会社 | 肺疾患の治療および／または予防剤 |
| JPWO2004087151A1 (ja) * | 2003-03-31 | 2006-06-29 | 協和醗酵工業株式会社 | 医薬組成物 |
| EP1634606A1 (en) * | 2003-03-31 | 2006-03-15 | Kyowa Hakko Kogyo Co., Ltd. | Drug for airway administration |
| WO2004087149A1 (ja) * | 2003-03-31 | 2004-10-14 | Kyowa Hakko Kogyo Co. Ltd. | 医薬組成物 |
| JPWO2004087147A1 (ja) * | 2003-03-31 | 2006-06-29 | 協和醗酵工業株式会社 | 肺疾患の治療および／または予防剤 |
| WO2004087146A1 (ja) * | 2003-03-31 | 2004-10-14 | Kyowa Hakko Kogyo Co., Ltd. | 微粒子混合物の製造方法 |
| JPWO2004112791A1 (ja) * | 2003-06-23 | 2006-07-27 | 協和醗酵工業株式会社 | 肺疾患の治療および／または予防剤 |
| EP1504756A1 (en) * | 2003-08-06 | 2005-02-09 | Kyowa Hakko Kogyo Co., Ltd | Medicament compositions comprising a heterocyclic compound and an anticholinergic |
| CA2584169A1 (en) * | 2004-10-13 | 2006-04-20 | Kyowa Hakko Kogyo Co., Ltd. | Remedies/preventives for chronic skin disease |
| CA2584261A1 (en) * | 2004-10-13 | 2006-04-20 | Kyowa Hakko Kogyo Co., Ltd. | Pharmaceutical composition |
| WO2006123726A1 (ja) * | 2005-05-18 | 2006-11-23 | Kyowa Hakko Kogyo Co., Ltd. | 医薬組成物 |
| US20100056791A1 (en) * | 2006-09-01 | 2010-03-04 | Yasushi Kohno | Pyrazolopyridine carboxamide derivative and phosphodiesterase (pde) inhibitor containing the same |
| CA2661992A1 (en) * | 2006-09-06 | 2008-03-13 | Kyorin Pharmaceutical Co., Ltd. | Pyrazolopyridine derivative and phosphodiesterase (pde) inhibitor containing the same as active ingredient |
| CA2673370C (en) * | 2006-12-22 | 2015-11-17 | Leo Pharma A/S | Substituted acetophenones useful as pde4 inhibitors |
| KR101571654B1 (ko) * | 2007-02-28 | 2015-11-25 | 레오 파마 에이/에스 | 신규한 포스포디에스테라제 억제제 |
| CN101679428A (zh) | 2007-04-16 | 2010-03-24 | 利奥制药有限公司 | 用于治疗皮肤疾病的作为磷酸二酯酶抑制剂的三唑并吡啶类 |
| EP2379548B1 (en) | 2008-12-19 | 2016-03-09 | Leo Pharma A/S | Triazolopyridines as phosphodiesterase inhibitors for treatment of dermal diseases |
| EP2585469B1 (en) | 2010-06-24 | 2016-05-25 | Leo Pharma A/S | Benzodioxole or benzodioxepine heterocyclic compounds as phosphodiesterase inhibitors |
| CA2858123A1 (en) | 2011-12-21 | 2013-06-27 | Leo Pharma A/S | [1,2,4]triazolopyridines and their use as phosphodiesterase inhibitors |
| JP6785666B2 (ja) * | 2014-06-23 | 2020-11-18 | レオ ファーマ アクティーゼルスカブ | １，３−ベンゾジオキソール複素環化合物の調製方法 |
| CN106588841B (zh) * | 2015-10-19 | 2019-01-25 | 富乐马鸿凯（大连）医药有限公司 | 合成2,3-二氢-1-苯并呋喃-4-甲醛的方法 |
| CN106588900A (zh) * | 2015-10-20 | 2017-04-26 | 北京康辰医药科技有限公司 | 一种苯并双环化合物或其药学上可接受的盐、药物组合物及其应用 |
| CN106905336B (zh) * | 2017-01-22 | 2019-04-09 | 浙江工业大学 | 一种手性吡唑螺呋喃类化合物的不对称合成方法 |
| CN107325067B (zh) * | 2017-05-03 | 2020-05-12 | 广州中医药大学 | 磷酸二酯酶4抑制剂桑辛素m衍生物及其用途 |
| CN109721580B (zh) * | 2017-10-27 | 2022-11-04 | 中国医学科学院药物研究所 | 3-苯基-7,8-脱氢葡萄藤戊素衍生物、其制法和药物组合物与用途 |
| CN109721579B (zh) * | 2017-10-27 | 2022-11-04 | 中国医学科学院药物研究所 | 7,8-脱氢葡萄藤戊素衍生物、其制法和药物组合物与用途 |
| CN114478413B (zh) * | 2022-01-14 | 2023-06-23 | 北京富盛嘉华医药科技有限公司 | 2-(2′-羟基-3′-甲代烯丙基-5′-甲基苯基)苯并三氮唑的制备方法及应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2507604A2 (fr) * | 1977-04-19 | 1982-12-17 | Delalande Sa | Nouvelles trimethoxy-3,4,5 cinnamoyle piperazines, leur procede de preparation et leur application en therapeutique |
| CA1297877C (en) * | 1983-12-22 | 1992-03-24 | Daniel Lednicer | Benzofurancarboxamides useful as antiemetic or antipsychotic agents |
| JPS62234083A (ja) * | 1986-02-28 | 1987-10-14 | アーバモント インク ディビーエイ アドリヤ ラボラトリーズ | 鎮吐薬または精神病治療薬として有用なカルボキサミド類 |
| JPH01207267A (ja) * | 1987-03-05 | 1989-08-21 | Yamanouchi Pharmaceut Co Ltd | ピリジン誘導体及び該化合物を含有する肝疾患治療剤 |
| ZA886585B (en) * | 1987-09-08 | 1990-05-30 | Lilly Co Eli | Specific 5-ht,antagonists |
| US5366986A (en) * | 1988-04-15 | 1994-11-22 | T Cell Sciences, Inc. | Compounds which inhibit complement and/or suppress immune activity |
| EP0607373B1 (en) * | 1992-06-15 | 1997-03-19 | Celltech Therapeutics Limited | Trisubstituted phenyl derivatives as selective phosphodiesterase iv inhibitors |
| MX9700557A (es) * | 1994-07-22 | 1997-12-31 | Byk Gulden Lomberg Chem Fab | Dihidrobenzofuranos. |
| US5902824A (en) * | 1995-05-18 | 1999-05-11 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Phenyldihydrobenzofuranes |
-
1996
- 1996-05-20 EP EP96915194A patent/EP0771794B1/en not_active Expired - Lifetime
- 1996-05-20 ES ES96915194T patent/ES2258775T3/es not_active Expired - Lifetime
- 1996-05-20 PT PT96915194T patent/PT771794E/pt unknown
- 1996-05-20 AT AT96915194T patent/ATE325110T1/de not_active IP Right Cessation
- 1996-05-20 JP JP53470896A patent/JP4172817B2/ja not_active Expired - Fee Related
- 1996-05-20 KR KR1019970700326A patent/KR100445356B1/ko not_active IP Right Cessation
- 1996-05-20 WO PCT/JP1996/001327 patent/WO1996036624A1/ja active IP Right Grant
- 1996-05-20 AU AU57029/96A patent/AU705690B2/en not_active Ceased
- 1996-05-20 CA CA002195755A patent/CA2195755A1/en not_active Abandoned
- 1996-05-20 DE DE69636086T patent/DE69636086T2/de not_active Expired - Fee Related
- 1996-05-20 DK DK96915194T patent/DK0771794T3/da active
- 1996-05-20 CN CNB961905298A patent/CN1163493C/zh not_active Expired - Fee Related
-
1997
- 1997-01-14 NO NO19970151A patent/NO317631B1/no unknown
- 1997-11-28 HK HK97102285A patent/HK1000785A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996036624A1 (fr) | 1996-11-21 |
| ATE325110T1 (de) | 2006-06-15 |
| AU5702996A (en) | 1996-11-29 |
| DE69636086T2 (de) | 2006-11-30 |
| PT771794E (pt) | 2006-09-29 |
| JP4172817B2 (ja) | 2008-10-29 |
| EP0771794A4 (en) | 1998-09-02 |
| CA2195755A1 (en) | 1996-11-21 |
| ES2258775T3 (es) | 2006-09-01 |
| NO970151D0 (no) | 1997-01-14 |
| EP0771794A1 (en) | 1997-05-07 |
| KR970704724A (ko) | 1997-09-06 |
| AU705690B2 (en) | 1999-05-27 |
| NO317631B1 (no) | 2004-11-29 |
| KR100445356B1 (ko) | 2004-11-12 |
| NO970151L (no) | 1997-03-06 |
| CN1154697A (zh) | 1997-07-16 |
| EP0771794B1 (en) | 2006-05-03 |
| DK0771794T3 (da) | 2006-09-11 |
| DE69636086D1 (de) | 2006-06-08 |
| CN1163493C (zh) | 2004-08-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1000785A1 (en) | Oxygen-containing heterocyclic compounds | |
| ID17851A (id) | Persenyawaan heterosiklis, produksi dan pemakaiannya | |
| LU91210I2 (fr) | Emodepside & Praziquantel ainsi que leurs dérivés pharmaceutiqement acceptables (PROFENDER) | |
| DE69617788T2 (de) | Aromatische Hydroxamsäure-Verbindungen, ihre Herstellung und Verwendung | |
| HU9502512D0 (en) | Anthranilic acid derivative | |
| AU9107491A (en) | 1,4-benzothiazepine derivative | |
| DE69918695D1 (de) | Sauerstoffhaltige heterocyclische verbindungen | |
| ATE263771T1 (de) | Totalsynthese von acylfulvenen mit antitumorwirkung | |
| DE69505470T2 (de) | Pyrrolocarbazol | |
| GR3032198T3 (en) | Androstenones | |
| AU2148595A (en) | 4,6-di-t-butyl-2,3-dihydrobenzothiophene derivative | |
| FI895229A0 (fi) | Foereningar foer behandling av urininkontinens och framstaellning daerav. | |
| ES2112489T3 (es) | Derivados carboxilato que presentan una actividad inhibidora de la fosfolipasa a2. | |
| ATE215082T1 (de) | Herboxidien-derivate und ihre herstellung aus einer streptomyces gex1 kultur | |
| AU1424795A (en) | Indole derivative |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20100520 |