GB9823071D0 - A method - Google Patents

A method

Info

Publication number
GB9823071D0
GB9823071D0 GBGB9823071.7A GB9823071A GB9823071D0 GB 9823071 D0 GB9823071 D0 GB 9823071D0 GB 9823071 A GB9823071 A GB 9823071A GB 9823071 D0 GB9823071 D0 GB 9823071D0
Authority
GB
United Kingdom
Prior art keywords
protein
asn
residues
randomisation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB9823071.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AFFIBODY TECHNOLOGY AB
Original Assignee
AFFIBODY TECHNOLOGY AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AFFIBODY TECHNOLOGY AB filed Critical AFFIBODY TECHNOLOGY AB
Priority to GBGB9823071.7A priority Critical patent/GB9823071D0/en
Publication of GB9823071D0 publication Critical patent/GB9823071D0/en
Priority to AT99950942T priority patent/ATE305970T1/de
Priority to JP2000577291A priority patent/JP4801258B2/ja
Priority to AU63532/99A priority patent/AU773368B2/en
Priority to US09/830,080 priority patent/US6831161B1/en
Priority to EP05077192A priority patent/EP1672068A1/en
Priority to CA2633345A priority patent/CA2633345C/en
Priority to EP99950942A priority patent/EP1123389B1/en
Priority to DK99950942T priority patent/DK1123389T3/da
Priority to DE69927598T priority patent/DE69927598T2/de
Priority to PCT/GB1999/003484 priority patent/WO2000023580A1/en
Priority to CA002347960A priority patent/CA2347960C/en
Priority to NO20011969A priority patent/NO323994B1/no
Priority to ZA200103252A priority patent/ZA200103252B/en
Priority to US11/000,747 priority patent/US20050100970A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GBGB9823071.7A 1998-10-21 1998-10-21 A method Ceased GB9823071D0 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
GBGB9823071.7A GB9823071D0 (en) 1998-10-21 1998-10-21 A method
CA002347960A CA2347960C (en) 1998-10-21 1999-10-21 A method of affinity separation and ligands for use therein
CA2633345A CA2633345C (en) 1998-10-21 1999-10-21 A method of affinity separation and ligands for use therein
DK99950942T DK1123389T3 (da) 1998-10-21 1999-10-21 Fremgangsmåde til affinitetsseparation samt ligander til anvendelse derved
AU63532/99A AU773368B2 (en) 1998-10-21 1999-10-21 A method of affinity separation and ligands for use therein
US09/830,080 US6831161B1 (en) 1998-10-21 1999-10-21 Method of affinity separation and ligands for use therein
EP05077192A EP1672068A1 (en) 1998-10-21 1999-10-21 A method of affinity separation and ligands for use therein
AT99950942T ATE305970T1 (de) 1998-10-21 1999-10-21 Verfahren zur affinitätstrennung und ligande zur pertinenten verwendung
EP99950942A EP1123389B1 (en) 1998-10-21 1999-10-21 A method of affinity separation and ligands for use therein
JP2000577291A JP4801258B2 (ja) 1998-10-21 1999-10-21 アフィニティ分離の方法及びそれに用いるリガンド
DE69927598T DE69927598T2 (de) 1998-10-21 1999-10-21 Verfahren zur Affinitätstrennung und Liganden zur pertinenten Verwendung
PCT/GB1999/003484 WO2000023580A1 (en) 1998-10-21 1999-10-21 A method of affinity separation and ligands for use therein
ZA200103252A ZA200103252B (en) 1998-10-21 2001-04-20 A method of affinity separation and ligands for use therein.
NO20011969A NO323994B1 (no) 1998-10-21 2001-04-20 Fremgangsmate for affinitetsseparasjon, samt albuminbindingsprotein, fusjonsprotein, nukleinsyremolekyl og vertscelle.
US11/000,747 US20050100970A1 (en) 1998-10-21 2004-12-01 Method of affinity separation and ligands for use therein

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9823071.7A GB9823071D0 (en) 1998-10-21 1998-10-21 A method

Publications (1)

Publication Number Publication Date
GB9823071D0 true GB9823071D0 (en) 1998-12-16

Family

ID=10841043

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9823071.7A Ceased GB9823071D0 (en) 1998-10-21 1998-10-21 A method

Country Status (12)

Country Link
US (2) US6831161B1 (enExample)
EP (2) EP1672068A1 (enExample)
JP (1) JP4801258B2 (enExample)
AT (1) ATE305970T1 (enExample)
AU (1) AU773368B2 (enExample)
CA (2) CA2347960C (enExample)
DE (1) DE69927598T2 (enExample)
DK (1) DK1123389T3 (enExample)
GB (1) GB9823071D0 (enExample)
NO (1) NO323994B1 (enExample)
WO (1) WO2000023580A1 (enExample)
ZA (1) ZA200103252B (enExample)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0200943D0 (sv) 2002-03-25 2002-03-25 Amersham Biosciences Ab Mutant protein
US7709209B2 (en) 2002-03-25 2010-05-04 Ge Healthcare Bio-Sciences Ab Protein ligands
GB0214007D0 (en) * 2002-06-18 2002-07-31 Common Services Agency Removal of prion infectivity
EP1634076A2 (en) * 2003-06-10 2006-03-15 CatchMabs B.V. Binding peptides: methods for their generation and use
SE0301936D0 (sv) * 2003-06-30 2003-06-30 Affibody Ab New polypeptide
WO2005003156A1 (en) * 2003-07-04 2005-01-13 Affibody Ab Polypeptides having binding affinity for her2
WO2005097202A2 (en) 2004-04-06 2005-10-20 Affibody Ab Use of serum albumin binding peptides conjugates for the preparation of a medicament
AU2007300751B2 (en) 2006-09-29 2012-01-19 Cytiva Bioprocess R&D Ab Chromatography ligand comprising Domain C from Staphyloccocus aureus protein A for antibody isolation
EP2190863B1 (en) * 2007-07-31 2015-09-02 Affibody AB New albumin binding compositions, methods and uses
GB2452301A (en) * 2007-08-30 2009-03-04 Ge Healthcare Bio Sciences Ab Sterilization Method
US8592555B2 (en) 2008-08-11 2013-11-26 Emd Millipore Corporation Immunoglobulin-binding proteins with improved specificity
WO2010035757A1 (ja) * 2008-09-25 2010-04-01 Jsr株式会社 アフィニティークロマトグラフィー用充填剤
JP5229888B2 (ja) * 2008-09-30 2013-07-03 独立行政法人産業技術総合研究所 弱酸性域での易解離性を向上したプロテインａ変異型タンパク質及び抗体捕捉剤
SG195555A1 (en) 2008-12-24 2013-12-30 Emd Millipore Corp Caustic stable chromatography ligands
EP2412809B1 (en) 2009-03-24 2017-08-09 Kaneka Corporation Protein having affinity for immunoglobulin, and immunoglobulin-binding affinity ligand
WO2011118699A1 (ja) 2010-03-24 2011-09-29 株式会社カネカ 免疫グロブリンに特異的に結合するタンパク質および免疫グロブリン結合性アフィニティーリガンド
JP5997176B2 (ja) * 2010-12-21 2016-09-28 ザ ユニバーシティ オブ ウエスタン オンタリオＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ ｏｆ Ｗｅｓｔｅｒｎ Ｏｎｔａｒｉｏ プロテインａの新規アルカリ抵抗性変異体及びアフィニティークロマトグラフィーにおけるその使用
CN103270044B (zh) 2010-12-21 2016-03-09 Jsr株式会社 亲和色谱用载体和分离免疫球蛋白的方法
JP6038774B2 (ja) 2011-03-24 2016-12-07 株式会社カネカ タンパク性物質結合性低分子化合物
SG193950A1 (en) 2011-03-25 2013-11-29 Kaneka Corp Novel immunoglobulin-binding polypeptide
SG186552A1 (en) 2011-06-08 2013-01-30 Emd Millipore Corp Chromatography matrices including novel staphylococcus aureus protein a based ligands
WO2014076179A1 (en) 2012-11-14 2014-05-22 Affibody Ab New polypeptide
WO2014076177A1 (en) * 2012-11-14 2014-05-22 Affibody Ab New polypeptide
US9255262B2 (en) * 2013-03-06 2016-02-09 Vision Global Holdings Ltd. Albumin-binding arginine deminase and the use thereof
USRE48805E1 (en) 2013-03-06 2021-11-02 Vision Global Holdings Ltd. Method for cancer targeting treatment and detection of arginine using albumin-binding arginine deiminase fusion protein
US11014129B2 (en) 2013-09-04 2021-05-25 Emd Millipore Corporation Methods of cleaning a protein A based affinity chromatography column
JP6491600B2 (ja) 2013-09-27 2019-03-27 株式会社カネカ アルカリ水溶液を用いた多孔質セルロースビーズの製造方法
WO2015088677A1 (en) 2013-12-12 2015-06-18 Emd Millipore Corporation Protein separations using an acrylamide containing filter
JP6369807B2 (ja) * 2014-10-21 2018-08-08 株式会社プロテイン・エクスプレス プロテインｌ変異体
JP6663360B2 (ja) 2015-01-26 2020-03-11 株式会社カネカ 変異型免疫グロブリンκ鎖可変領域結合性ペプチド
WO2016121701A1 (ja) 2015-01-26 2016-08-04 株式会社カネカ 免疫グロブリンκ鎖可変領域含有タンパク質精製用アフィニティー分離マトリックス
EP3276002B1 (en) 2015-03-26 2020-04-29 JSR Corporation Immunoglobulin-binding protein and affinity carrier using same
EP3875477A1 (en) 2015-04-17 2021-09-08 Alpine Immune Sciences, Inc. Immunomodulatory proteins with tunable affinities
EP3375873B1 (en) 2015-10-22 2025-07-02 Protenova Co., Ltd. Immunoglobulin-binding polypeptide
WO2017191748A1 (ja) * 2016-05-02 2017-11-09 株式会社カネカ 改変型免疫グロブリンκ鎖可変領域結合性ペプチド
WO2017195638A1 (ja) 2016-05-09 2017-11-16 株式会社カネカ 抗体またはκ鎖可変領域含有抗体断片の精製方法
EP3592759A1 (en) 2017-03-07 2020-01-15 JMVA Biotech AB Modified adsorptive surfaces
US11753449B2 (en) 2017-09-25 2023-09-12 Jsr Corporation Immunoglobulin binding protein, and affinity support using same
JP7724061B2 (ja) 2018-04-11 2025-08-15 インヒブルクス バイオサイエンシズ インコーポレイテッド 制約されたｃｄ３結合を有する多重特異性ポリペプチド構築物ならびに関連する方法および使用
US12428451B2 (en) 2018-08-24 2025-09-30 Jsr Corporation Immunoglobulin-binding protein, and affinity carrier using same
JP2023551353A (ja) 2020-10-13 2023-12-08 アヴィタイド エルエルシー ３へリックスバンドルタンパク質の親和性リガンドライブラリー及びその使用
CN116670150A (zh) 2020-12-22 2023-08-29 普罗泰纳瓦株式会社 免疫球蛋白结合多肽
WO2022178396A1 (en) 2021-02-19 2022-08-25 Avitide LLC Aav2 affinity agents
GB2609185A (en) 2021-05-24 2023-02-01 Astrea Uk Services Ltd Scaffold for isolation of a biomolecule
EP4541814A1 (en) * 2023-10-20 2025-04-23 Cytiva BioProcess R&D AB Stabilized polypeptides

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE462046C (sv) * 1982-08-23 1998-04-27 Pharmacia Biotech Ab Hybrid-DNA-vektor innehållande DNA-sekvens från Staphylococcus aureus, förfarande för dess framställning och bakterie innehållande densamma
US5401832A (en) * 1984-12-24 1995-03-28 Merck & Co., Inc. Brain derived and recombinant acidic fibroblast growth factor
US5089473A (en) * 1988-08-29 1992-02-18 Monsanto Company Somatotropin variants and their use
EP0863210A3 (en) * 1991-07-25 1999-09-22 Oriental Yeast Co., Ltd. Immunoglobulin-binding artificial protein
JP2584697B2 (ja) * 1991-08-23 1997-02-26 オリエンタル酵母工業株式会社 ＩｇＧ精製用組換え型プロテインＡ
DE59306762D1 (de) * 1992-04-16 1997-07-24 Merck Patent Gmbh Aktivierte Trägermaterialien, ihre Herstellung und Verwendung
SE9400088D0 (sv) 1994-01-14 1994-01-14 Kabi Pharmacia Ab Bacterial receptor structures
US5736499A (en) * 1995-06-06 1998-04-07 Genencor International, Inc. Mutant A-amylase
SE9503925D0 (sv) * 1995-11-07 1995-11-07 Pharmacia Biotech Ab Separationsmedium för IgG
EP0968290B1 (en) * 1997-03-12 2004-12-15 SmithKline Beecham Corporation Anti-alphavbeta3 humanized monoclonal antibodies

Also Published As

Publication number Publication date
ZA200103252B (en) 2002-07-22
NO20011969D0 (no) 2001-04-20
CA2633345A1 (en) 2000-04-27
JP2002527107A (ja) 2002-08-27
DK1123389T3 (da) 2006-01-16
CA2347960A1 (en) 2000-04-27
CA2347960C (en) 2008-08-05
CA2633345C (en) 2013-02-26
AU6353299A (en) 2000-05-08
EP1123389A1 (en) 2001-08-16
AU773368B2 (en) 2004-05-20
ATE305970T1 (de) 2005-10-15
DE69927598D1 (de) 2006-02-16
DE69927598T2 (de) 2006-07-13
NO323994B1 (no) 2007-07-30
US20050100970A1 (en) 2005-05-12
NO20011969L (no) 2001-06-19
EP1672068A1 (en) 2006-06-21
WO2000023580A1 (en) 2000-04-27
US6831161B1 (en) 2004-12-14
EP1123389B1 (en) 2005-10-05
JP4801258B2 (ja) 2011-10-26

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)