ATE305970T1 - Verfahren zur affinitätstrennung und ligande zur pertinenten verwendung - Google Patents
Verfahren zur affinitätstrennung und ligande zur pertinenten verwendungInfo
- Publication number
- ATE305970T1 ATE305970T1 AT99950942T AT99950942T ATE305970T1 AT E305970 T1 ATE305970 T1 AT E305970T1 AT 99950942 T AT99950942 T AT 99950942T AT 99950942 T AT99950942 T AT 99950942T AT E305970 T1 ATE305970 T1 AT E305970T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- affinity separation
- ligands
- asn
- residues
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9823071.7A GB9823071D0 (en) | 1998-10-21 | 1998-10-21 | A method |
PCT/GB1999/003484 WO2000023580A1 (en) | 1998-10-21 | 1999-10-21 | A method of affinity separation and ligands for use therein |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE305970T1 true ATE305970T1 (de) | 2005-10-15 |
Family
ID=10841043
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99950942T ATE305970T1 (de) | 1998-10-21 | 1999-10-21 | Verfahren zur affinitätstrennung und ligande zur pertinenten verwendung |
Country Status (12)
Country | Link |
---|---|
US (2) | US6831161B1 (de) |
EP (2) | EP1672068A1 (de) |
JP (1) | JP4801258B2 (de) |
AT (1) | ATE305970T1 (de) |
AU (1) | AU773368B2 (de) |
CA (2) | CA2347960C (de) |
DE (1) | DE69927598T2 (de) |
DK (1) | DK1123389T3 (de) |
GB (1) | GB9823071D0 (de) |
NO (1) | NO323994B1 (de) |
WO (1) | WO2000023580A1 (de) |
ZA (1) | ZA200103252B (de) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0200943D0 (sv) * | 2002-03-25 | 2002-03-25 | Amersham Biosciences Ab | Mutant protein |
US7709209B2 (en) | 2002-03-25 | 2010-05-04 | Ge Healthcare Bio-Sciences Ab | Protein ligands |
GB0214007D0 (en) * | 2002-06-18 | 2002-07-31 | Common Services Agency | Removal of prion infectivity |
AU2004245429A1 (en) * | 2003-06-10 | 2004-12-16 | Farallone Holding Bv | Binding peptides: methods for their generation and use |
SE0301936D0 (sv) * | 2003-06-30 | 2003-06-30 | Affibody Ab | New polypeptide |
WO2005003156A1 (en) * | 2003-07-04 | 2005-01-13 | Affibody Ab | Polypeptides having binding affinity for her2 |
US8642743B2 (en) | 2004-04-06 | 2014-02-04 | Affibody Ab | Method for reducing the immune response to a biologically active protein |
CN101522278B (zh) | 2006-09-29 | 2016-08-10 | 通用电气健康护理生物科学股份公司 | 用于抗体分离的包含来自金黄色葡萄球菌a蛋白的结构域c的层析配体 |
EP2190863B1 (de) * | 2007-07-31 | 2015-09-02 | Affibody AB | Neue albuminbindende zusammensetzungen, verfahren und anwendungen |
GB2452301A (en) | 2007-08-30 | 2009-03-04 | Ge Healthcare Bio Sciences Ab | Sterilization Method |
US8592555B2 (en) * | 2008-08-11 | 2013-11-26 | Emd Millipore Corporation | Immunoglobulin-binding proteins with improved specificity |
US8846877B2 (en) * | 2008-09-25 | 2014-09-30 | Jsr Corporation | Packing material for affinity chromatography |
JP5229888B2 (ja) * | 2008-09-30 | 2013-07-03 | 独立行政法人産業技術総合研究所 | 弱酸性域での易解離性を向上したプロテインa変異型タンパク質及び抗体捕捉剤 |
SG195555A1 (en) | 2008-12-24 | 2013-12-30 | Emd Millipore Corp | Caustic stable chromatography ligands |
EP2412809B1 (de) | 2009-03-24 | 2017-08-09 | Kaneka Corporation | Protein mit immunglobulinaffinität und ligand mit affinität für immunglobulinbindung |
JP5952185B2 (ja) | 2010-03-24 | 2016-07-13 | 株式会社カネカ | 免疫グロブリンに特異的に結合するタンパク質および免疫グロブリン結合性アフィニティーリガンド |
CN103270044B (zh) | 2010-12-21 | 2016-03-09 | Jsr株式会社 | 亲和色谱用载体和分离免疫球蛋白的方法 |
JP5997176B2 (ja) * | 2010-12-21 | 2016-09-28 | ザ ユニバーシティ オブ ウエスタン オンタリオThe University of Western Ontario | プロテインaの新規アルカリ抵抗性変異体及びアフィニティークロマトグラフィーにおけるその使用 |
JP6038774B2 (ja) | 2011-03-24 | 2016-12-07 | 株式会社カネカ | タンパク性物質結合性低分子化合物 |
WO2012133342A1 (ja) | 2011-03-25 | 2012-10-04 | 株式会社カネカ | 免疫グロブリン結合性新規ポリペプチド |
SG186552A1 (en) | 2011-06-08 | 2013-01-30 | Emd Millipore Corp | Chromatography matrices including novel staphylococcus aureus protein a based ligands |
WO2014076177A1 (en) * | 2012-11-14 | 2014-05-22 | Affibody Ab | New polypeptide |
WO2014076179A1 (en) | 2012-11-14 | 2014-05-22 | Affibody Ab | New polypeptide |
US9255262B2 (en) * | 2013-03-06 | 2016-02-09 | Vision Global Holdings Ltd. | Albumin-binding arginine deminase and the use thereof |
USRE48805E1 (en) | 2013-03-06 | 2021-11-02 | Vision Global Holdings Ltd. | Method for cancer targeting treatment and detection of arginine using albumin-binding arginine deiminase fusion protein |
CA2923133C (en) | 2013-09-04 | 2019-05-28 | Emd Millipore Corporation | Methods of cleaning a protein a based affinity chromatography column |
EP3459631A1 (de) | 2013-09-27 | 2019-03-27 | Kaneka Corporation | Verfahren zur herstellung poröser celluloseperlen unter verwendung einer wässrigen alkalilösung und durch dieses verfahren hergestellte poröse celluloseperlen |
SG10201804200WA (en) | 2013-12-12 | 2018-07-30 | Emd Millipore Corp | Protein separations using an acrylamide containing filter |
JP6369807B2 (ja) * | 2014-10-21 | 2018-08-08 | 株式会社プロテイン・エクスプレス | プロテインl変異体 |
JPWO2016121701A1 (ja) | 2015-01-26 | 2017-11-09 | 株式会社カネカ | 免疫グロブリンκ鎖可変領域含有タンパク質精製用アフィニティー分離マトリックス |
EP3252158A4 (de) | 2015-01-26 | 2018-07-18 | Kaneka Corporation | Mutantes immunglobulin-kappa-ketten-bindendes protein mit variabler region |
JP6705806B2 (ja) | 2015-03-26 | 2020-06-03 | Jsr株式会社 | イムノグロブリン結合タンパク質およびそれを用いたアフィニティー担体 |
CN107969128A (zh) | 2015-04-17 | 2018-04-27 | 高山免疫科学股份有限公司 | 具有可调的亲和力的免疫调节蛋白 |
CN108291220B (zh) | 2015-10-22 | 2022-10-28 | 普罗泰纳瓦株式会社 | 免疫球蛋白结合多肽 |
WO2017191748A1 (ja) * | 2016-05-02 | 2017-11-09 | 株式会社カネカ | 改変型免疫グロブリンκ鎖可変領域結合性ペプチド |
WO2017195638A1 (ja) | 2016-05-09 | 2017-11-16 | 株式会社カネカ | 抗体またはκ鎖可変領域含有抗体断片の精製方法 |
WO2018162501A1 (en) | 2017-03-07 | 2018-09-13 | Jmva Biotech Ab | Modified adsorptive surfaces |
EP3689894A4 (de) | 2017-09-25 | 2021-12-22 | JSR Corporation | Immunglobulin-bindendes protein und affinitätsträger damit |
EP3842536A4 (de) | 2018-08-24 | 2023-01-18 | JSR Corporation | Immunglobulin-bindendes protein und affinitätsträger damit |
KR20230112616A (ko) | 2020-10-13 | 2023-07-27 | 아비타이드 엘엘씨 | 3중-나선 번들 단백질들의 친화성 리간드 라이브러리 및 이의 용도 |
EP4269590A1 (de) | 2020-12-22 | 2023-11-01 | Protenova Co., Ltd. | Immunglobulinbindendes polypeptid |
CN117241866A (zh) | 2021-02-19 | 2023-12-15 | 艾维泰有限责任公司 | Aav2亲和剂 |
GB2609185A (en) | 2021-05-24 | 2023-02-01 | Astrea Uk Services Ltd | Scaffold for isolation of a biomolecule |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8204810L (sv) * | 1982-08-23 | 1984-02-24 | Pharmacia Fine Chemicals Ab | Hybrid-dna-molekyl, transformerad mikroorganism och sett att framstella protein a |
US5401832A (en) * | 1984-12-24 | 1995-03-28 | Merck & Co., Inc. | Brain derived and recombinant acidic fibroblast growth factor |
US5089473A (en) * | 1988-08-29 | 1992-02-18 | Monsanto Company | Somatotropin variants and their use |
EP0863210A3 (de) * | 1991-07-25 | 1999-09-22 | Oriental Yeast Co., Ltd. | Künstliches Immunglobulinkombinierendes Protein |
JP2584697B2 (ja) * | 1991-08-23 | 1997-02-26 | オリエンタル酵母工業株式会社 | IgG精製用組換え型プロテインA |
EP0565978B1 (de) * | 1992-04-16 | 1997-06-18 | MERCK PATENT GmbH | Aktivierte Trägermaterialien, ihre Herstellung und Verwendung |
SE9400088D0 (sv) * | 1994-01-14 | 1994-01-14 | Kabi Pharmacia Ab | Bacterial receptor structures |
US5736499A (en) * | 1995-06-06 | 1998-04-07 | Genencor International, Inc. | Mutant A-amylase |
SE9503925D0 (sv) * | 1995-11-07 | 1995-11-07 | Pharmacia Biotech Ab | Separationsmedium för IgG |
WO1998040488A1 (en) * | 1997-03-12 | 1998-09-17 | Smithkline Beecham Corporation | Anti-alphabeta3 humanized monoclonal antibodies |
-
1998
- 1998-10-21 GB GBGB9823071.7A patent/GB9823071D0/en not_active Ceased
-
1999
- 1999-10-21 JP JP2000577291A patent/JP4801258B2/ja not_active Expired - Lifetime
- 1999-10-21 WO PCT/GB1999/003484 patent/WO2000023580A1/en active IP Right Grant
- 1999-10-21 DK DK99950942T patent/DK1123389T3/da active
- 1999-10-21 US US09/830,080 patent/US6831161B1/en not_active Expired - Lifetime
- 1999-10-21 EP EP05077192A patent/EP1672068A1/de not_active Ceased
- 1999-10-21 AU AU63532/99A patent/AU773368B2/en not_active Expired
- 1999-10-21 CA CA002347960A patent/CA2347960C/en not_active Expired - Lifetime
- 1999-10-21 DE DE69927598T patent/DE69927598T2/de not_active Expired - Lifetime
- 1999-10-21 AT AT99950942T patent/ATE305970T1/de not_active IP Right Cessation
- 1999-10-21 EP EP99950942A patent/EP1123389B1/de not_active Expired - Lifetime
- 1999-10-21 CA CA2633345A patent/CA2633345C/en not_active Expired - Lifetime
-
2001
- 2001-04-20 ZA ZA200103252A patent/ZA200103252B/en unknown
- 2001-04-20 NO NO20011969A patent/NO323994B1/no not_active IP Right Cessation
-
2004
- 2004-12-01 US US11/000,747 patent/US20050100970A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1123389B1 (de) | 2005-10-05 |
JP2002527107A (ja) | 2002-08-27 |
US6831161B1 (en) | 2004-12-14 |
NO20011969D0 (no) | 2001-04-20 |
DE69927598D1 (de) | 2006-02-16 |
CA2347960A1 (en) | 2000-04-27 |
JP4801258B2 (ja) | 2011-10-26 |
NO323994B1 (no) | 2007-07-30 |
CA2633345C (en) | 2013-02-26 |
GB9823071D0 (en) | 1998-12-16 |
NO20011969L (no) | 2001-06-19 |
CA2347960C (en) | 2008-08-05 |
DE69927598T2 (de) | 2006-07-13 |
AU773368B2 (en) | 2004-05-20 |
EP1672068A1 (de) | 2006-06-21 |
AU6353299A (en) | 2000-05-08 |
CA2633345A1 (en) | 2000-04-27 |
WO2000023580A1 (en) | 2000-04-27 |
US20050100970A1 (en) | 2005-05-12 |
DK1123389T3 (da) | 2006-01-16 |
ZA200103252B (en) | 2002-07-22 |
EP1123389A1 (de) | 2001-08-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE305970T1 (de) | Verfahren zur affinitätstrennung und ligande zur pertinenten verwendung | |
ATE123780T1 (de) | Verfahren zur verwendung und herstellung von peptiden. | |
WO2002004523A3 (en) | Artificial antibody polypeptides | |
ATE236537T1 (de) | Verfahren zur erzeugung von proteinhydrolysaten | |
WO2004056865A3 (en) | Method of modulation of interaction between receptor and ligand | |
ATE386802T1 (de) | Künstliche antikörperpolypeptide | |
DE69827844D1 (de) | Verfahren zur herstellung von teilen aus pulvern unter verwendung von aus metallsalz gewonnenen bindern | |
DE69840112D1 (de) | Verfahren zur Sichtung von Phagen-Display-Bibliotheken mit unterschiedlichen Liganden | |
DE69632887D1 (de) | Verfahren zur zweckmässige Herstellung von Transglutaminase durch DNA-Rekombination | |
ATE252532T1 (de) | Verfahren zur herstellung von 3,3- dimethylbutyraldehyd durch oxidation von 3,3- dimethylbutanol | |
DE69913969D1 (de) | Verfahren zur herstellung von porösem kalziniertem polyimid | |
DE69633563D1 (de) | Neues verfahren zur gewinnung und reinigung von fusionsproteinen | |
DE59804785D1 (de) | Verbessertes Verfahren zur Stabilisierung von Proteinen | |
ATE330962T1 (de) | Phosphonite, ihre verwendung als ligand in übergangsmetall komplexen und verfahren zur herstellung von nitrilen | |
DE69904971D1 (de) | Verfahren zur Abtrennung von Serum aus Vollblut | |
ATE223491T1 (de) | Verfahren zur reinigung von biomolekül- oder proteinkomplexen | |
DE69802523D1 (de) | Verfahren zur herstellung von sinterteilen aus einer eisenbasispulvermischung | |
DE69836496D1 (de) | Verfahren zur herstellung von beta-(1,3)-d-glukan aus pilzen | |
DE69901100T2 (de) | Verfahren zur herstellung von kugelförmigen teilchen aus oxyden | |
ATE216778T1 (de) | Verfahren zur herstellung von konjugaten aus einem spezifischen bindungspartner und einem kohlenhydrathaltigen protein | |
ATE291040T1 (de) | Katalysatorsystem und verfahren zur dessen herstellung und dessen verwendung in einem polymerisationsverfahren | |
WO2003054517A3 (en) | Methods for detecting half-antibodies using chip-based gel electrophoresis | |
DE69428454T2 (de) | Verfahren zur freisetzung bindender proteine von liganden | |
DE69505660D1 (de) | Ein enzymatisches verfahren zur herstellung eines gewünschten proteins aus einem am aminoterminus verlängerten protein | |
ATE269905T1 (de) | Verfahren zur herstellung von proteinen in wirtszellen unter verwendung von chaperoninen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |