ATE123780T1 - Verfahren zur verwendung und herstellung von peptiden. - Google Patents

Verfahren zur verwendung und herstellung von peptiden.

Info

Publication number
ATE123780T1
ATE123780T1 AT90903300T AT90903300T ATE123780T1 AT E123780 T1 ATE123780 T1 AT E123780T1 AT 90903300 T AT90903300 T AT 90903300T AT 90903300 T AT90903300 T AT 90903300T AT E123780 T1 ATE123780 T1 AT E123780T1
Authority
AT
Austria
Prior art keywords
mixture
producing peptides
specific binding
entities
binding
Prior art date
Application number
AT90903300T
Other languages
English (en)
Inventor
Hendrik Mario Lot Geysen
Original Assignee
Chiron Mimotopes Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Mimotopes Pty Ltd filed Critical Chiron Mimotopes Pty Ltd
Application granted granted Critical
Publication of ATE123780T1 publication Critical patent/ATE123780T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT90903300T 1989-02-17 1990-02-16 Verfahren zur verwendung und herstellung von peptiden. ATE123780T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPJ278889 1989-02-17

Publications (1)

Publication Number Publication Date
ATE123780T1 true ATE123780T1 (de) 1995-06-15

Family

ID=3773722

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90903300T ATE123780T1 (de) 1989-02-17 1990-02-16 Verfahren zur verwendung und herstellung von peptiden.

Country Status (12)

Country Link
US (2) US5539084A (de)
EP (2) EP0628570A1 (de)
JP (1) JPH04504416A (de)
AT (1) ATE123780T1 (de)
AU (1) AU642403B2 (de)
CA (1) CA2047191A1 (de)
DE (1) DE69020143T2 (de)
DK (1) DK0458841T3 (de)
ES (1) ES2075196T3 (de)
NO (1) NO301279B1 (de)
NZ (1) NZ232562A (de)
WO (1) WO1990009395A1 (de)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5866363A (en) 1985-08-28 1999-02-02 Pieczenik; George Method and means for sorting and identifying biological information
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
WO1991002078A1 (en) 1989-08-07 1991-02-21 Peptide Technology Ltd Tumour necrosis factor binding ligands
US20030225254A1 (en) * 1989-08-07 2003-12-04 Rathjen Deborah Ann Tumour necrosis factor binding ligands
US5959087A (en) * 1989-08-07 1999-09-28 Peptide Technology, Ltd. Tumour necrosis factor binding ligands
DE3935572A1 (de) * 1989-10-25 1991-05-02 Biotechnolog Forschung Gmbh Verfahren zur peptidsynthese und traeger dafuer
WO1992010588A1 (en) 1990-12-06 1992-06-25 Affymax Technologies N.V. Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides
US20010021513A1 (en) * 1991-11-21 2001-09-13 Puijk Wouter Cornelis Test device comprising a plate containing a multiplicity of wells with an associated metering device, as well as a kit which comprises these devices and use of the devices
EP0545198B1 (de) * 1991-11-29 1999-09-15 Hoechst Aktiengesellschaft Peptide mit insulinartiger Wirkung
WO1994002508A2 (en) * 1992-07-22 1994-02-03 Proteus Molecular Design Limited Polypeptide antigens of mycobacterium bovis
US5702672A (en) * 1992-10-08 1997-12-30 Warner-Lambert Company Apparatus and method for multiple simultaneous synthesis
US5714127A (en) * 1992-10-08 1998-02-03 Warner-Lambert Company System for multiple simultaneous synthesis
US5324483B1 (en) * 1992-10-08 1996-09-24 Warner Lambert Co Apparatus for multiple simultaneous synthesis
US5567391A (en) * 1992-10-08 1996-10-22 Warner-Lambert Company Apparatus for multiple simultaneous synthesis
WO1994011388A1 (en) * 1992-11-06 1994-05-26 Chiron Mimotopes Pty. Ltd. Support for the synthesis of modular polymers
ATE210993T1 (de) * 1993-06-21 2002-01-15 Selectide Corp Selektiv spaltbare verbindungen, die auf iminodiessigsäure-ester-bindungen basieren
US5380668A (en) * 1993-07-06 1995-01-10 University Of Utah Research Foundation Compounds having the antigenicity of hCG
ATE235504T1 (de) * 1994-12-30 2003-04-15 Chiron Corp Verfahren zur kontrollierten synthese von beliebigen peptidmischungen kodierende polynukleotidmischungen
US5958792A (en) * 1995-06-07 1999-09-28 Chiron Corporation Combinatorial libraries of substrate-bound cyclic organic compounds
US6432716B2 (en) * 1995-10-03 2002-08-13 The Penn State Research Foundation Method to identify a surface-bound molecule
US7517952B1 (en) * 1997-02-25 2009-04-14 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US20060024301A1 (en) * 1997-02-25 2006-02-02 Corixa Corporation Prostate-specific polypeptides and fusion polypeptides thereof
US20030185830A1 (en) * 1997-02-25 2003-10-02 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US20060269532A1 (en) * 1997-02-25 2006-11-30 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
CA2281104A1 (en) * 1997-02-26 1998-09-03 University Of Hawaii Selective epoxidation process for preparing pharmaceutical compounds
US6294344B1 (en) * 1997-03-19 2001-09-25 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian cancer
US7335351B2 (en) * 1997-03-19 2008-02-26 The University Of Arkansas For Medical Sciences Immunotherapeutic methods targeted towards stratum corneum chymotryptic enzyme
US7282198B2 (en) * 1997-03-19 2007-10-16 The University Of Arkansas For Medical Sciences Immunotherapeutic methods targeted towards stratum corneum chymotryptic enzyme
US7084239B1 (en) * 1997-10-08 2006-08-01 The United States Of America As Represented By The Department Of Health And Human Services Cancer peptides of NY-ESO-1/CAG-3
US20020061848A1 (en) * 2000-07-20 2002-05-23 Ajay Bhatia Compounds and methods for treatment and diagnosis of chlamydial infection
US20030235594A1 (en) * 1999-09-14 2003-12-25 Antigen Express, Inc. Ii-Key/antigenic epitope hybrid peptide vaccines
US9289487B2 (en) * 1999-09-14 2016-03-22 Antigen Express, Inc. II-key/antigenic epitope hybrid peptide vaccines
US6432409B1 (en) * 1999-09-14 2002-08-13 Antigen Express, Inc. Hybrid peptides modulate the immune response
US6919187B2 (en) * 2000-04-21 2005-07-19 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US6656700B2 (en) 2000-05-26 2003-12-02 Amersham Plc Isoforms of human pregnancy-associated protein-E
US20020076835A1 (en) * 2000-07-14 2002-06-20 Ede Nicholas Jon Modular grafted polymeric surfaces
JP4503801B2 (ja) * 2000-09-08 2010-07-14 独立行政法人科学技術振興機構 新規ヒト癌・精巣抗原及びその遺伝子
US20020123474A1 (en) * 2000-10-04 2002-09-05 Shannon Mark E. Human GTP-Rho binding protein2
JP4194365B2 (ja) * 2000-10-31 2008-12-10 エムジーアイ ファーマ バイオロジックス インコーポレイテッド Ｃｙｐ１ｂ１核酸および使用の方法
AU2002247304A1 (en) * 2001-03-07 2002-09-19 Mannkind Corporation Anti-neovasculature preparations for cancer
US20040078837A1 (en) * 2001-08-02 2004-04-22 Shannon Mark E. Four human zinc-finger-containing proteins: MDZ3, MDZ4, MDZ7 and MDZ12
WO2003072746A2 (en) * 2002-02-26 2003-09-04 Genencor International, Inc. Subtilisin carlsberg proteins with reduced immunogenicity
WO2004016733A2 (en) * 2002-08-16 2004-02-26 Agensys, Inc. Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer
US7179645B2 (en) * 2002-09-24 2007-02-20 Antigen Express, Inc. Ii-Key/antigenic epitope hybrid peptide vaccines
EP1556072B1 (de) 2002-09-17 2010-05-19 Antigen Express, Inc. Ii-key/antigene epitop-hybrid-peptid-vakzine
US6910785B2 (en) * 2003-01-22 2005-06-28 Cooper Technologies Company Industrial luminaire with prismatic refractor
US20040185499A1 (en) * 2003-03-20 2004-09-23 Jolley Michael E. Method of epitope scanning using fluorescence polarization
US20050095648A1 (en) * 2003-10-30 2005-05-05 Mario Geysen Method for designing linear epitopes and algorithm therefor and polypeptide epitopes
KR101325194B1 (ko) * 2005-07-27 2013-11-06 온코세라피 사이언스 가부시키가이샤 대장암 관련 유전자 ｔｏｍ３４
CA2628241C (en) 2005-11-07 2016-02-02 Indiana University Research And Technology Corporation Glucagon analogs exhibiting physiological solubility and stability
AU2008205229B2 (en) * 2007-01-05 2014-03-27 Indiana University Research And Technology Corporation Glucagon analogs exhibiting enhanced solubility in physiological pH buffers
KR20150116465A (ko) 2007-02-15 2015-10-15 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 글루카곤/ｇｌｐ-1 수용체 공동-항진물질
EP2044949A1 (de) 2007-10-05 2009-04-08 Immutep Verwendung von rekombinantem LAG-3 oder Derivaten daraus zur Auslösung einer Monozyten-Immunreaktion
CA2702289A1 (en) * 2007-10-30 2009-05-07 Indiana University Research And Technology Corporation Compounds exhibiting glucagon antagonist and glp-1 agonist activity
CA2707861A1 (en) 2007-10-30 2009-05-07 Indiana University Research And Technology Corporation Glucagon antagonists
WO2009099763A1 (en) * 2008-01-30 2009-08-13 Indiana University Research And Technology Corporation Ester-based peptide prodrugs
JP5753779B2 (ja) * 2008-06-17 2015-07-22 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションＩｎｄｉａｎａ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ 生理学的ｐＨの緩衝液中で向上した溶解性及び安定性を示すグルカゴン類縁体
EP2952202B1 (de) * 2008-06-17 2017-10-18 Indiana University Research and Technology Corporation Gip-basierte gemischte agonisten zur behandlung von stoffwechselkrankheiten und fettleibigkeit
NZ589847A (en) 2008-06-17 2013-01-25 Univ Indiana Res & Tech Corp Glucagon/glp-1 receptor co-agonists
AR074811A1 (es) 2008-12-19 2011-02-16 Univ Indiana Res & Tech Corp Profarmaco de peptido de la superfamilia de glucagon basados en amida
WO2010088393A2 (en) * 2009-01-28 2010-08-05 Antigen Express, Inc. Li-kay hybrid peptides that modulate the immune response to influenza
KR20120087875A (ko) 2009-06-16 2012-08-07 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 Ｇｉｐ 수용체-활성 글루카곤 화합물
EP2512503A4 (de) 2009-12-18 2013-08-21 Univ Indiana Res & Tech Corp Coagonisten des glucagon/glp-1 rezeptors
MX2012008603A (es) 2010-01-27 2013-01-25 Univ Indiana Res & Tech Corp Conjugados de antagonista de glucagon-agonista de gip y composiciones para el tratamiento de desordenes metabolicos y obesidad.
CA2797095A1 (en) 2010-05-13 2011-11-17 Indiana University Research And Technology Corporation Glucagon superfamily peptides exhibiting nuclear hormone receptor activity
CA2797089A1 (en) 2010-05-13 2011-11-17 Indiana University Research And Technology Corporation Glucagon superfamily peptides exhibiting g protein-coupled receptor activity
WO2011163012A2 (en) 2010-06-24 2011-12-29 Indiana University Research And Technology Corporation Amide based glucagon superfamily peptide prodrugs
WO2012055509A1 (en) 2010-10-29 2012-05-03 Lonza Ltd Diketopiperazine forming dipeptidyl linker
WO2012073459A1 (en) 2010-12-02 2012-06-07 Oncotherapy Science, Inc. Tomm34 peptides and vaccines including the same
BR112013015389A2 (pt) 2010-12-22 2016-11-22 Univ Indiana Res & Tech Corp análogo de glucagon exibindo atividade de receptor gip
CN103857408B (zh) 2011-06-22 2017-04-12 印第安那大学科技研究公司 胰高血糖素/glp‑1受体协同激动剂
RU2014101697A (ru) 2011-06-22 2015-07-27 Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн Коагонисты рецепторов глюкагона/glp-1
RU2014117678A (ru) 2011-11-17 2015-12-27 Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн Пептиды глюкагонового суперсемейства, обладающие глюкокортикоидной рецепторной активностью
EP2639299A1 (de) 2012-03-16 2013-09-18 Invectys Aus Telomerase abgeleitete, universelle Krebspeptide
EP2864351B1 (de) 2012-06-21 2016-08-10 Indiana University Research and Technology Corporation Glucagonanaloga mit gip-rezeptoraktivität
US20160024169A1 (en) 2013-03-14 2016-01-28 Indiana University Research And Technology Corporation Insulin-incretin conjugates
DK2978444T3 (en) 2013-03-28 2019-03-18 Invectys CANCERVACCINE FOR DOGS
US9931387B2 (en) 2013-03-28 2018-04-03 Invectys Cancer vaccine for cats
SG11201603118TA (en) 2013-10-28 2016-05-30 Invectys A telomerase encoding dna vaccine
ES2753412T3 (es) 2013-10-28 2020-04-08 Invectys Electrotransferencia génica a las células de la piel
GB201322626D0 (en) 2013-12-19 2014-02-05 Immutep S A Combined preparations for the treatment of cancer
US9682123B2 (en) 2013-12-20 2017-06-20 The Trustees Of Columbia University In The City Of New York Methods of treating metabolic disease
WO2016049190A1 (en) 2014-09-24 2016-03-31 Indiana University Research And Technology Corporation Incretin-insulin conjugates
GB201500374D0 (en) 2015-01-09 2015-02-25 Immutep S A Combined preparations for the treatment of cancer
EP3334498B1 (de) 2015-08-12 2023-06-07 The Trustees of Columbia University in the City of New York Verfahren zur behandlung von volumendepletion und nierenverletzung
WO2018206512A1 (en) 2017-05-09 2018-11-15 Invectys Recombinant measles vaccine expressing htert

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983001A (en) * 1972-05-10 1976-09-28 Ceskoslovenska Akademie Ved Isolation of biologically active compounds by affinity chromatography
US3988307A (en) * 1974-09-06 1976-10-26 The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare Solid phase synthesis of peptides with carboxyl-terminal amides
US4963263A (en) * 1988-03-24 1990-10-16 Terrapin Technologies, Inc. Method of identity analyte-binding peptides
US5217869A (en) * 1987-10-13 1993-06-08 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
US5133866A (en) * 1988-03-24 1992-07-28 Terrapin Technologies, Inc. Method to identify analyte-bending ligands
US5340474A (en) * 1988-03-24 1994-08-23 Terrapin Technologies, Inc. Panels of analyte-binding ligands
US5409611A (en) * 1988-03-24 1995-04-25 Terrapin Technoogies, Inc. Method to identify analyte-binding ligands

Also Published As

Publication number Publication date
AU4986990A (en) 1990-08-23
JPH04504416A (ja) 1992-08-06
DE69020143T2 (de) 1996-01-25
US5783674A (en) 1998-07-21
ES2075196T3 (es) 1995-10-01
EP0458841A1 (de) 1991-12-04
CA2047191A1 (en) 1990-08-18
NO913186D0 (no) 1991-08-15
NO301279B1 (no) 1997-10-06
NO913186L (no) 1991-08-15
DK0458841T3 (da) 1995-11-20
US5539084A (en) 1996-07-23
EP0458841B1 (de) 1995-06-14
AU642403B2 (en) 1993-10-21
EP0628570A1 (de) 1994-12-14
NZ232562A (en) 1992-10-28
WO1990009395A1 (en) 1990-08-23
DE69020143D1 (de) 1995-07-20
EP0458841A4 (en) 1992-08-26

Similar Documents

Publication Publication Date Title
ATE123780T1 (de) Verfahren zur verwendung und herstellung von peptiden.
DE69019074D1 (de) Verfahren zur Fraktionierung von Plasmaproteinen.
DE3382190D1 (de) Immunogener protein- oder peptidkomplex, verfahren zur herstellung dieses komplexes und seine verwendung als immunstimulans und als impfstoff.
DE3688209D1 (de) Verfahren zur herstellung von kohlenstoffilamenten und durch dieses verfahren erhaltene kohlenstoffilamente.
DE3781548D1 (de) Verfahren zur verdichtung von materialvorformen.
WO1995018826A3 (en) Purified primate ctla-8 antigens and related reagents
DE58900372D1 (de) Verfahren zur abtrennung von kohlenwasserstoffen.
DE69028513D1 (de) Träger zur bindung von antiphospholipid-antikörpern, diese antikörper verwendender immunotest und kit dafür
DE3865963D1 (de) Elektrophoretisches gel hoher aufloesung sowie methode zur abscheidung von serumproteinen.
GR3018371T3 (en) Method for identifying or determining proteins and applications therefor.
ATE236984T1 (de) Verfahren zur herstellung von hydrophoben polypeptiden, proteinen und peptiden
DE3880082D1 (de) Verfahren zur herstellung von polyimid und verbundmaterial daraus.
DE3485711D1 (de) Immunoadsorbens und verfahren zur zurueckgewinnung von vitamin-k-abhaengigen proteinen mittels dieses adsorbens.
DE68913283D1 (de) Verfahren zur Abtrennung von Kohlendioxid.
DE69010155D1 (de) Verfahren zur Trennung von Aminosäuren.
DE68910771D1 (de) Verfahren zur Herstellung von verbessertem Proteinhydrolysat.
DE58904756D1 (de) Verfahren zur herstellung von tert.-amylalkohol (taa).
ATE216778T1 (de) Verfahren zur herstellung von konjugaten aus einem spezifischen bindungspartner und einem kohlenhydrathaltigen protein
DE3871179D1 (de) Verfahren zur destillativen trennung von gemischen.
DE59208543D1 (de) Künstliche Standard- und Kontrollseren zur Verwendung in Verfahren zur Bestimmung von Antikörpern
ATE83262T1 (de) Neue monoklonale antikoerper gegen ifn-omega, verfahren zu ihrer herstellung und deren verwendung zur reinigung sowie zum nachweis von ifn-omega.
DE59004279D1 (de) Verfahren zur C-terminalen Modifizierung von Proteinen.
DE3782986D1 (de) Verfahren zur trennung von n-geschuetzten alpha-l-aspartyl-l-phenylalaninen.
DE68918055D1 (de) Verfahren zur Abtrennung von Phenol.
DE3781722D1 (de) Verfahren zur adsorptiven trennung von dichlortoluen.