ATE123780T1 - Verfahren zur verwendung und herstellung von peptiden. - Google Patents

Verfahren zur verwendung und herstellung von peptiden.

Info

Publication number
ATE123780T1
ATE123780T1 AT90903300T AT90903300T ATE123780T1 AT E123780 T1 ATE123780 T1 AT E123780T1 AT 90903300 T AT90903300 T AT 90903300T AT 90903300 T AT90903300 T AT 90903300T AT E123780 T1 ATE123780 T1 AT E123780T1
Authority
AT
Austria
Prior art keywords
mixture
producing peptides
specific binding
entities
binding
Prior art date
Application number
AT90903300T
Other languages
English (en)
Inventor
Hendrik Mario Lot Geysen
Original Assignee
Chiron Mimotopes Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Mimotopes Pty Ltd filed Critical Chiron Mimotopes Pty Ltd
Application granted granted Critical
Publication of ATE123780T1 publication Critical patent/ATE123780T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047Simultaneous synthesis of different peptide species; Peptide libraries
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/824Immunological separation techniques
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT90903300T 1989-02-17 1990-02-16 Verfahren zur verwendung und herstellung von peptiden. ATE123780T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPJ278889 1989-02-17

Publications (1)

Publication Number Publication Date
ATE123780T1 true ATE123780T1 (de) 1995-06-15

Family

ID=3773722

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90903300T ATE123780T1 (de) 1989-02-17 1990-02-16 Verfahren zur verwendung und herstellung von peptiden.

Country Status (12)

Country Link
US (2) US5539084A (de)
EP (2) EP0628570A1 (de)
JP (1) JPH04504416A (de)
AT (1) ATE123780T1 (de)
AU (1) AU642403B2 (de)
CA (1) CA2047191A1 (de)
DE (1) DE69020143T2 (de)
DK (1) DK0458841T3 (de)
ES (1) ES2075196T3 (de)
NO (1) NO301279B1 (de)
NZ (1) NZ232562A (de)
WO (1) WO1990009395A1 (de)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5866363A (en) 1985-08-28 1999-02-02 Pieczenik; George Method and means for sorting and identifying biological information
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5959087A (en) * 1989-08-07 1999-09-28 Peptide Technology, Ltd. Tumour necrosis factor binding ligands
US20030225254A1 (en) * 1989-08-07 2003-12-04 Rathjen Deborah Ann Tumour necrosis factor binding ligands
JP3443119B2 (ja) 1989-08-07 2003-09-02 ペプテック リミテッド 腫瘍壊死因子結合リガンド
DE3935572A1 (de) * 1989-10-25 1991-05-02 Biotechnolog Forschung Gmbh Verfahren zur peptidsynthese und traeger dafuer
WO1992010588A1 (en) 1990-12-06 1992-06-25 Affymax Technologies N.V. Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides
US20010021513A1 (en) * 1991-11-21 2001-09-13 Puijk Wouter Cornelis Test device comprising a plate containing a multiplicity of wells with an associated metering device, as well as a kit which comprises these devices and use of the devices
DE59209745D1 (de) * 1991-11-29 1999-10-21 Hoechst Ag Peptide mit insulinartiger Wirkung
AU4580093A (en) * 1992-07-22 1994-02-14 Proteus Molecular Design Limited Polypeptide antigens of mycobacterium bovis
US5714127A (en) * 1992-10-08 1998-02-03 Warner-Lambert Company System for multiple simultaneous synthesis
US5324483B1 (en) * 1992-10-08 1996-09-24 Warner Lambert Co Apparatus for multiple simultaneous synthesis
US5565173A (en) * 1992-10-08 1996-10-15 Warner-Lambert Company Apparatus and method for multiple simultaneous synthesis
US5702672A (en) * 1992-10-08 1997-12-30 Warner-Lambert Company Apparatus and method for multiple simultaneous synthesis
CA2148591A1 (en) * 1992-11-06 1994-05-26 H. Mario Geysen Support for the synthesis of modular polymers
PT1156059E (pt) * 1993-06-21 2007-10-19 Aventis Pharma Inc Ligantes cliváveis selectivamente com base num grupo de metionina e um grupo éster
US5380668A (en) * 1993-07-06 1995-01-10 University Of Utah Research Foundation Compounds having the antigenicity of hCG
AU4522196A (en) * 1994-12-30 1996-07-24 Chiron Corporation Method for the controlled synthesis of polynucleotide mixtures which encode desired mixtures of peptides
US5958792A (en) * 1995-06-07 1999-09-28 Chiron Corporation Combinatorial libraries of substrate-bound cyclic organic compounds
US6432716B2 (en) * 1995-10-03 2002-08-13 The Penn State Research Foundation Method to identify a surface-bound molecule
US20060269532A1 (en) * 1997-02-25 2006-11-30 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US20060024301A1 (en) * 1997-02-25 2006-02-02 Corixa Corporation Prostate-specific polypeptides and fusion polypeptides thereof
US7517952B1 (en) * 1997-02-25 2009-04-14 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US20030185830A1 (en) * 1997-02-25 2003-10-02 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
EA002547B1 (ru) * 1997-02-26 2002-06-27 Эли Лилли Энд Компани Способ селективного эпоксидирования для получения лекарственных соединений
US7282198B2 (en) * 1997-03-19 2007-10-16 The University Of Arkansas For Medical Sciences Immunotherapeutic methods targeted towards stratum corneum chymotryptic enzyme
US6294344B1 (en) * 1997-03-19 2001-09-25 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian cancer
US7335351B2 (en) * 1997-03-19 2008-02-26 The University Of Arkansas For Medical Sciences Immunotherapeutic methods targeted towards stratum corneum chymotryptic enzyme
US7084239B1 (en) * 1997-10-08 2006-08-01 The United States Of America As Represented By The Department Of Health And Human Services Cancer peptides of NY-ESO-1/CAG-3
US20020061848A1 (en) * 2000-07-20 2002-05-23 Ajay Bhatia Compounds and methods for treatment and diagnosis of chlamydial infection
US20030235594A1 (en) * 1999-09-14 2003-12-25 Antigen Express, Inc. Ii-Key/antigenic epitope hybrid peptide vaccines
US6432409B1 (en) * 1999-09-14 2002-08-13 Antigen Express, Inc. Hybrid peptides modulate the immune response
US9289487B2 (en) * 1999-09-14 2016-03-22 Antigen Express, Inc. II-key/antigenic epitope hybrid peptide vaccines
US6919187B2 (en) * 2000-04-21 2005-07-19 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US6656700B2 (en) 2000-05-26 2003-12-02 Amersham Plc Isoforms of human pregnancy-associated protein-E
WO2002006384A1 (en) * 2000-07-14 2002-01-24 Mimotopes Pty Ltd Activated modular grafted polymeric surfaces
JP4503801B2 (ja) * 2000-09-08 2010-07-14 独立行政法人科学技術振興機構 新規ヒト癌・精巣抗原及びその遺伝子
US20020123474A1 (en) * 2000-10-04 2002-09-05 Shannon Mark E. Human GTP-Rho binding protein2
US7241742B2 (en) * 2000-10-31 2007-07-10 Mgi Pharma Biologics, Inc. CYP1B1 nucleic acids and methods of use
EP2295074A1 (de) * 2001-03-07 2011-03-16 Mannkind Corporation Anti-Neovaskulatur Präparationen zur Krebsbehandlung
US20040078837A1 (en) * 2001-08-02 2004-04-22 Shannon Mark E. Four human zinc-finger-containing proteins: MDZ3, MDZ4, MDZ7 and MDZ12
EP1530637B1 (de) * 2002-02-26 2010-02-10 Genencor International, Inc. Subtilisin-carlsberg-proteine mit verminderter immunogenität
AU2003243151A1 (en) * 2002-08-16 2004-03-03 Agensys, Inc. Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer
JP2006515744A (ja) 2002-09-17 2006-06-08 アンテイジエン・エクスプレス・インコーポレーテツド Ii−Key/抗原性エピトープハイブリッドペプチドワクチン
US7179645B2 (en) * 2002-09-24 2007-02-20 Antigen Express, Inc. Ii-Key/antigenic epitope hybrid peptide vaccines
US6910785B2 (en) * 2003-01-22 2005-06-28 Cooper Technologies Company Industrial luminaire with prismatic refractor
US20040185499A1 (en) * 2003-03-20 2004-09-23 Jolley Michael E. Method of epitope scanning using fluorescence polarization
US20050095648A1 (en) * 2003-10-30 2005-05-05 Mario Geysen Method for designing linear epitopes and algorithm therefor and polypeptide epitopes
KR20130087639A (ko) * 2005-07-27 2013-08-06 온코세라피 사이언스 가부시키가이샤 대장암 관련 유전자 tom34
EP1959986B1 (de) 2005-11-07 2014-07-23 Indiana University Research and Technology Corporation Glucagon-analoga mit physiologischer löslichkeit und stabilität
WO2008086086A2 (en) * 2007-01-05 2008-07-17 Indiana University Research And Technology Corporation Glucagon analogs exhibiting enhanced solubility in physiological ph buffers
EP2111414B1 (de) 2007-02-15 2014-07-02 Indiana University Research and Technology Corporation Coagonisten des glucagon/glp-1 rezeptors
EP2044949A1 (de) 2007-10-05 2009-04-08 Immutep Verwendung von rekombinantem LAG-3 oder Derivaten daraus zur Auslösung einer Monozyten-Immunreaktion
MX2010004297A (es) * 2007-10-30 2010-05-03 Univ Indiana Res & Tech Corp Antagonistas de glucagon.
JP5771005B2 (ja) * 2007-10-30 2015-08-26 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation グルカゴンアンタゴニスト及びglp−1アゴニスト活性を示す化合物
EP2249853A4 (de) * 2008-01-30 2012-12-26 Univ Indiana Res & Tech Corp Peptid-prodrugs auf esterbasis
CA2728284C (en) 2008-06-17 2019-09-10 Richard D. Dimarchi Glucagon/glp-1 receptor co-agonists
AU2009274425B2 (en) * 2008-06-17 2014-05-15 Indiana University Research And Technology Corporation GIP-based mixed agonists for treatment of metabolic disorders and obesity
CN104447980A (zh) * 2008-06-17 2015-03-25 印第安纳大学研究及科技有限公司 在生理pH缓冲液中具有增强的溶解性和稳定性的胰高血糖素类似物
TWI489992B (zh) 2008-12-19 2015-07-01 印地安那大學研究及技術公司 醯胺系胰高血糖素超級家族之胜肽前驅藥物
JP2012516350A (ja) * 2009-01-28 2012-07-19 アンティジェン・エクスプレス・インコーポレーテッド インフルエンザに対する免疫応答を調節するIi−Keyハイブリッドペプチド
CN102459325B (zh) 2009-06-16 2015-03-25 印第安纳大学科技研究有限公司 胃抑胜肽受体活化的胰高血糖素化合物
WO2011075393A2 (en) 2009-12-18 2011-06-23 Indiana University Research And Technology Corporation Glucagon/glp-1 receptor co-agonists
CA2788304A1 (en) 2010-01-27 2011-08-04 Indiana University Research And Technology Corporation Glucagon antagonist - gip agonist conjugates and compositions for the treatment of metabolic disorders and obesity
RU2604067C2 (ru) 2010-05-13 2016-12-10 Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн Пептиды глюкагонового суперсемейства, обладающие активностью относительно ядерных гормональных рецепторов
JP6050746B2 (ja) 2010-05-13 2016-12-21 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation Gタンパク質共役受容体活性を示すグルカゴンスーパーファミリーのペプチド
EP2588126A4 (de) 2010-06-24 2015-07-08 Univ Indiana Res & Tech Corp Amidbasierte glucagon-superfamilien-peptid-prodrugs
WO2012055509A1 (en) 2010-10-29 2012-05-03 Lonza Ltd Diketopiperazine forming dipeptidyl linker
CA2819463C (en) 2010-12-02 2018-10-23 Oncotherapy Science, Inc. Tomm34 peptides and vaccines including the same
CA2821766A1 (en) 2010-12-22 2012-06-28 Indiana University Research And Technology Corporation Glucagon analogs exhibiting gip receptor activity
CN103857408B (zh) 2011-06-22 2017-04-12 印第安那大学科技研究公司 胰高血糖素/glp‑1受体协同激动剂
EP2723766A4 (de) 2011-06-22 2015-05-20 Univ Indiana Res & Tech Corp Coagonisten des glucagon/glp-1 rezeptors
EP2780031B1 (de) 2011-11-17 2018-03-07 Indiana University Research and Technology Corporation Peptide aus der glucagon-überfamilie mit glucocorticoid-rezeptor-wirkung
EP2639299A1 (de) * 2012-03-16 2013-09-18 Invectys Aus Telomerase abgeleitete, universelle Krebspeptide
KR20150023013A (ko) 2012-06-21 2015-03-04 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 수용체 활성을 나타내는 글루카곤 유사체
RU2678134C2 (ru) 2013-03-14 2019-01-23 Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн Конъюгаты инсулин-инкретин
CA2908138A1 (en) 2013-03-28 2014-10-02 Invectys A cancer vaccine for cats
AU2014242916B2 (en) 2013-03-28 2018-08-02 Invectys A cancer vaccine for dogs
BR112016008807B1 (pt) 2013-10-28 2021-07-06 Invectys uso de um ácido nucleico
DK3062824T3 (da) 2013-10-28 2020-02-17 Invectys Telomerase-kodende dna-vaccine
GB201322626D0 (en) 2013-12-19 2014-02-05 Immutep S A Combined preparations for the treatment of cancer
US9682123B2 (en) 2013-12-20 2017-06-20 The Trustees Of Columbia University In The City Of New York Methods of treating metabolic disease
ES2822994T3 (es) 2014-09-24 2021-05-05 Univ Indiana Res & Tech Corp Conjugados de incretina-insulina
GB201500374D0 (en) 2015-01-09 2015-02-25 Immutep S A Combined preparations for the treatment of cancer
EP3334498B1 (de) 2015-08-12 2023-06-07 The Trustees of Columbia University in the City of New York Verfahren zur behandlung von volumendepletion und nierenverletzung
US11351246B2 (en) 2017-05-09 2022-06-07 Invectys SAS Recombinant measles vaccine expressing hTERT
WO2024181781A1 (ko) * 2023-02-27 2024-09-06 에스피투티엑스주식회사 응집 방지 기능을 갖는 생물학적 고분자 합성용 기재 및 이를 이용한 생물학적 고분자 합성 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983001A (en) * 1972-05-10 1976-09-28 Ceskoslovenska Akademie Ved Isolation of biologically active compounds by affinity chromatography
US3988307A (en) * 1974-09-06 1976-10-26 The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare Solid phase synthesis of peptides with carboxyl-terminal amides
US5217869A (en) * 1987-10-13 1993-06-08 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
US4963263A (en) * 1988-03-24 1990-10-16 Terrapin Technologies, Inc. Method of identity analyte-binding peptides
US5133866A (en) * 1988-03-24 1992-07-28 Terrapin Technologies, Inc. Method to identify analyte-bending ligands
US5340474A (en) * 1988-03-24 1994-08-23 Terrapin Technologies, Inc. Panels of analyte-binding ligands
US5409611A (en) * 1988-03-24 1995-04-25 Terrapin Technoogies, Inc. Method to identify analyte-binding ligands

Also Published As

Publication number Publication date
US5783674A (en) 1998-07-21
ES2075196T3 (es) 1995-10-01
NZ232562A (en) 1992-10-28
EP0458841A4 (en) 1992-08-26
NO301279B1 (no) 1997-10-06
JPH04504416A (ja) 1992-08-06
AU642403B2 (en) 1993-10-21
US5539084A (en) 1996-07-23
EP0458841B1 (de) 1995-06-14
EP0458841A1 (de) 1991-12-04
DK0458841T3 (da) 1995-11-20
NO913186D0 (no) 1991-08-15
NO913186L (no) 1991-08-15
WO1990009395A1 (en) 1990-08-23
CA2047191A1 (en) 1990-08-18
EP0628570A1 (de) 1994-12-14
DE69020143D1 (de) 1995-07-20
DE69020143T2 (de) 1996-01-25
AU4986990A (en) 1990-08-23

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