DE3882154D1 - Verfahren zur herstellung des pres 1/s2/s-hepatitis-b-antigens aus hefe. - Google Patents
Verfahren zur herstellung des pres 1/s2/s-hepatitis-b-antigens aus hefe.Info
- Publication number
- DE3882154D1 DE3882154D1 DE8888301382T DE3882154T DE3882154D1 DE 3882154 D1 DE3882154 D1 DE 3882154D1 DE 8888301382 T DE8888301382 T DE 8888301382T DE 3882154 T DE3882154 T DE 3882154T DE 3882154 D1 DE3882154 D1 DE 3882154D1
- Authority
- DE
- Germany
- Prior art keywords
- yeast
- hepatitis
- antigent
- pres
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1982087A | 1987-02-27 | 1987-02-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3882154D1 true DE3882154D1 (de) | 1993-08-12 |
DE3882154T2 DE3882154T2 (de) | 1993-12-02 |
Family
ID=21795203
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE88301382T Expired - Fee Related DE3882154T2 (de) | 1987-02-27 | 1988-02-18 | Verfahren zur Herstellung des pres 1/S2/S-Hepatitis-B-Antigens aus Hefe. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0280470B1 (de) |
JP (1) | JPS63270628A (de) |
AT (1) | ATE91304T1 (de) |
DE (1) | DE3882154T2 (de) |
DK (1) | DK100888A (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0291146B1 (de) * | 1987-03-09 | 1993-09-01 | Merck & Co. Inc. | Reinigung von rekombiniertem Hepatitis-B-Oberflächen-Antigen |
EP0314240A3 (de) * | 1987-10-26 | 1990-03-28 | Merck & Co. Inc. | Verfahren für de Reinigung von rekombinanten Hepatitis-Antigenen |
US5011915A (en) * | 1987-10-26 | 1991-04-30 | Merck & Co., Inc. | Process for purifying recombinant hepatitis antigens |
JPH0216975A (ja) * | 1988-02-09 | 1990-01-19 | Eugene Tech Internatl Inc | 異成分混交性のプレーsに富んだb型肝炎表面抗原 |
IL99025A0 (en) * | 1990-08-15 | 1992-07-15 | Astra Ab | Novel process for the detection of pathogens using dna probes |
CU22290A1 (es) * | 1990-10-08 | 1995-01-31 | Cigb | Procedimiento para la obtencion de antigeno de superficie del virus de la hepatitis b de superior capacidad inmunoganica y su uso en un preparado vacunal |
US5102989A (en) * | 1991-03-15 | 1992-04-07 | Merck & Co., Inc. | Method of stabilizing recombinant hepatitis B virus surface proteins from recombinant host cells |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR76274B (de) * | 1981-08-04 | 1984-08-04 | Univ California | |
KR850001534A (ko) * | 1983-08-22 | 1985-03-30 | 제임스 에프. 나우톤 | 형질전환된 효모로 부터 유도된 면역원성 HBsAg |
US4649192A (en) * | 1985-05-30 | 1987-03-10 | Smith Kline-Rit | Method for the isolation and purification of hepatitis B surface antigen using polysorbate |
JPS63501121A (ja) * | 1985-08-15 | 1988-04-28 | アムジエン | 酵母細胞からb型肝炎表面抗原を抽出するための細胞溶解法および緩衝液 |
US4895800A (en) * | 1985-11-26 | 1990-01-23 | Phillips Petroleum Company | Yeast production of hepatitis B surface antigen |
-
1988
- 1988-02-18 DE DE88301382T patent/DE3882154T2/de not_active Expired - Fee Related
- 1988-02-18 AT AT88301382T patent/ATE91304T1/de not_active IP Right Cessation
- 1988-02-18 EP EP88301382A patent/EP0280470B1/de not_active Expired - Lifetime
- 1988-02-26 DK DK100888A patent/DK100888A/da not_active Application Discontinuation
- 1988-02-26 JP JP63042449A patent/JPS63270628A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE3882154T2 (de) | 1993-12-02 |
EP0280470B1 (de) | 1993-07-07 |
DK100888D0 (da) | 1988-02-26 |
ATE91304T1 (de) | 1993-07-15 |
EP0280470A1 (de) | 1988-08-31 |
JPS63270628A (ja) | 1988-11-08 |
DK100888A (da) | 1988-10-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |