GB882335A - Improvements in or relating to substances produced from penicillin-producing moulds - Google Patents
Improvements in or relating to substances produced from penicillin-producing mouldsInfo
- Publication number
- GB882335A GB882335A GB2279159A GB2279159A GB882335A GB 882335 A GB882335 A GB 882335A GB 2279159 A GB2279159 A GB 2279159A GB 2279159 A GB2279159 A GB 2279159A GB 882335 A GB882335 A GB 882335A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- compounds
- chlorocinnamamido
- penicillin
- relating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Relates to compounds of the general formula: <FORM:0882335/IV (b)/1> where R1, R2 and R3 are the same or different and each represents a hydrogen atom or a nitro, amino, alkylamino, dialkylamino, alkanoylamino, alkyl, chloro, bromo, iodo, alkoxy, hydroxy or sulphanyl group such as 6-(2-chlorocinnamamido), 6-(4-chlorocinnamamido), 6-(2,3-dimethoxycinnamamido) and 6-(3-methylcinnamamido) penicillanic acid, and non-toxic salts thereof. The Specification refers to many other compounds of the above formula. The above compounds may be prepared by reacting 6-aminopenicillanic acid or a neutral salt thereof with an acid chloride of the general formula: <FORM:0882335/IV (b)/2> or with a functional equivalent thereof as an acylating agent for a primary amino group, such as the corresponding carboxylic acid bromides, acid anhydrides and mixed anhydrides with other carboxylic acids.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2279159A GB882335A (en) | 1959-07-02 | 1959-07-02 | Improvements in or relating to substances produced from penicillin-producing moulds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2279159A GB882335A (en) | 1959-07-02 | 1959-07-02 | Improvements in or relating to substances produced from penicillin-producing moulds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB882335A true GB882335A (en) | 1961-11-15 |
Family
ID=10185138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2279159A Expired GB882335A (en) | 1959-07-02 | 1959-07-02 | Improvements in or relating to substances produced from penicillin-producing moulds |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB882335A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3256272A (en) * | 1963-08-10 | 1966-06-14 | Meiji Seika Kaisha | Derivatives of alpha-thiocinnamyl penicillin |
| FR2100730A1 (en) * | 1970-06-06 | 1972-03-24 | Istituto Biochimico Italiano | Semisynthetic penicillin prodn - from 6-apa |
-
1959
- 1959-07-02 GB GB2279159A patent/GB882335A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3256272A (en) * | 1963-08-10 | 1966-06-14 | Meiji Seika Kaisha | Derivatives of alpha-thiocinnamyl penicillin |
| FR2100730A1 (en) * | 1970-06-06 | 1972-03-24 | Istituto Biochimico Italiano | Semisynthetic penicillin prodn - from 6-apa |
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