GB874414A - Antibacterial agents - Google Patents

Antibacterial agents

Info

Publication number
GB874414A
GB874414A GB16649/60A GB1664960A GB874414A GB 874414 A GB874414 A GB 874414A GB 16649/60 A GB16649/60 A GB 16649/60A GB 1664960 A GB1664960 A GB 1664960A GB 874414 A GB874414 A GB 874414A
Authority
GB
United Kingdom
Prior art keywords
acid
general formula
antibacterial agents
anhydrides
penicillanic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB16649/60A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Research Laboratories Ltd
Original Assignee
Beecham Research Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Research Laboratories Ltd filed Critical Beecham Research Laboratories Ltd
Publication of GB874414A publication Critical patent/GB874414A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Relates to penicillins of the general formula <FORM:0874414/IV (b)/1> where n is 2, 3 or 4 such as 6-(5-cyclohexyl-valeramido), 6-(3-cyclohexylpropionamido) and 6-(4-cyclohexylbutyramido) penicillanic acid and to non-toxic salts thereof, which may be prepared by reacting 6-amino-penicillanic acid, preferably in the form of a neutral salt such as the sodium or triethylamine salt, with an acid chloride of the general formula <FORM:0874414/IV (b)/2> where n is 2, 3 or 4, or its functional equivalent as an acylating agent for a primary amino group such as the corresponding acid bromides, acid anhydrides and mixed anhydrides with other carboxylic acids, including monoesters of carbonic acid.
GB16649/60A 1959-05-25 1960-05-11 Antibacterial agents Expired GB874414A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US874414XA 1959-05-25 1959-05-25

Publications (1)

Publication Number Publication Date
GB874414A true GB874414A (en) 1961-08-10

Family

ID=22205214

Family Applications (1)

Application Number Title Priority Date Filing Date
GB16649/60A Expired GB874414A (en) 1959-05-25 1960-05-11 Antibacterial agents

Country Status (1)

Country Link
GB (1) GB874414A (en)

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