GB894247A - Antibacterial agents - Google Patents
Antibacterial agentsInfo
- Publication number
- GB894247A GB894247A GB2738/61A GB273861A GB894247A GB 894247 A GB894247 A GB 894247A GB 2738/61 A GB2738/61 A GB 2738/61A GB 273861 A GB273861 A GB 273861A GB 894247 A GB894247 A GB 894247A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cyclohexyl
- acids
- acid
- general formula
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Relates to acids of the general formula <FORM:0894247/IV (b)/1> and non-toxic salts thereof, wherein R1 is a cyclopentyl, cyclohexyl, benzyl, allyl, benzhydryl, 2-phenylethyl or 3-phenyl-1-propyl group or an alkyl group having from 1 to 20 carbon atoms inclusive, and R2 is a cyclopenthyl, cyclohexyl or C1 to C6 alkyl group. Typical acids of the above formula are 6 - (a - butoxypropionamido), 6 - (a -cyclohexyl-oxypropionamido), 6 - (a - allyloxyisovaler-amido), and 6-(a -isobutoxyisovaleramido) penicillanic acid. The compounds may be prepared by reacting 6-aminopenicillanic acid or a neutral salt thereof with an acid chloride of the general formula <FORM:0894247/IV (b)/2> or with its functional equivalent as an acylating agent for a primary amino group, such as the corresponding carboxylic acid bromides, scid anhydrides and mixed anhydrides with other carboxylic acids.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US894247XA | 1960-01-25 | 1960-01-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB894247A true GB894247A (en) | 1962-04-18 |
Family
ID=22217562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2738/61A Expired GB894247A (en) | 1960-01-25 | 1961-01-24 | Antibacterial agents |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB894247A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3301849A (en) * | 1963-09-04 | 1967-01-31 | Bristol Myers Co | 6-(alpha-phenoxyalkanoylamino) thiopenicillanic acid |
-
1961
- 1961-01-24 GB GB2738/61A patent/GB894247A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3301849A (en) * | 1963-09-04 | 1967-01-31 | Bristol Myers Co | 6-(alpha-phenoxyalkanoylamino) thiopenicillanic acid |
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