GB201501017D0 - Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers - Google Patents
Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancersInfo
- Publication number
- GB201501017D0 GB201501017D0 GBGB1501017.6A GB201501017A GB201501017D0 GB 201501017 D0 GB201501017 D0 GB 201501017D0 GB 201501017 A GB201501017 A GB 201501017A GB 201501017 D0 GB201501017 D0 GB 201501017D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- peptides
- hcc
- cancers
- combination
- hepatocellular carcinoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 206010073071 hepatocellular carcinoma Diseases 0.000 title 2
- 231100000844 hepatocellular carcinoma Toxicity 0.000 title 2
- 102000004196 processed proteins & peptides Human genes 0.000 title 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 238000009169 immunotherapy Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001103—Receptors for growth factors
- A61K39/00111—Hepatocyte growth factor receptor [HGFR or c-met]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
- A61K51/1057—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from liver or pancreas
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Mycology (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
Priority Applications (149)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL19170191T PL3545965T3 (pl) | 2014-12-23 | 2015-12-16 | Nowe peptydy i kombinacja peptydów do stosowania w immunoterapii względem raka komórek wątroby (hcc) i innych rodzajów raka |
| EP19199098.5A EP3616706B1 (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| PE2021000187A PE20211740A1 (es) | 2014-12-23 | 2015-12-16 | Nuevos peptidos y nueva combinacion de peptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (chc) y otros tipos de cancer |
| MX2017008329A MX377144B (es) | 2014-12-23 | 2015-12-16 | Nuevos peptidos y nueva combinacion de peptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (chc) y otros tipos de cancer. |
| EP15813809.9A EP3236985B2 (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| KR1020177017192A KR102284493B1 (ko) | 2014-12-23 | 2015-12-16 | 간세포 암종(hcc) 및 기타 암들에 대한 면역요법에서의 사용을 위한 신규 펩티드 및 펩티드의 조합 |
| PH1/2017/500484A PH12017500484B1 (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| PL19199125T PL3626731T3 (pl) | 2014-12-23 | 2015-12-16 | Nowe peptydy i kombinacja peptydów do stosowania w immunoterapii względem raka komórek wątroby (hcc) i innych rodzajów raka |
| MA049157A MA49157A (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
| LTEP19199098.5T LT3616706T (lt) | 2014-12-23 | 2015-12-16 | Nauji peptidai ir peptidų deriniai, skirti naudoti imunoterapijai prieš hepatoceliulinę karcinomą (hck) ir kitų rūšių vėžį |
| SI201531746T SI3626731T1 (sl) | 2014-12-23 | 2015-12-16 | Novi peptidi in kombinacija peptidov za uporabo v imunoterapiji proti hepatocelularnem karcinomu (HCC) in drugim oblikam raka |
| PT158138099T PT3236985T (pt) | 2014-12-23 | 2015-12-16 | Novos péptidos e combinação de péptidos para utilização em imunoterapêutica contra o carcinoma hepatocelular (hcc) e outros cancros |
| SI201531682T SI3545965T1 (sl) | 2014-12-23 | 2015-12-16 | Novi peptidi in kombinacija peptidov za uporabo v imunoterapiji proti hepatocelularnem karcinomu (HCC)in drugim oblikam raka |
| EP19199101.7A EP3626729B1 (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| CA2972126A CA2972126A1 (en) | 2014-12-23 | 2015-12-16 | Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| EA201791150A EA201791150A1 (ru) | 2014-12-23 | 2015-12-16 | Новые пептиды и комбинации пептидов для применения в иммунотерапии гепатоклеточной карциномы (гкк) и других видов рака |
| CN202011429073.4A CN112646025A (zh) | 2014-12-23 | 2015-12-16 | 用于肝细胞癌(hcc)和其他癌症免疫治疗的新型肽和肽组合物 |
| AU2015371490A AU2015371490B2 (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| KR1020227028464A KR102643923B1 (ko) | 2014-12-23 | 2015-12-16 | 간세포 암종(hcc) 및 기타 암들에 대한 면역요법에서의 사용을 위한 신규 펩티드 및 펩티드의 조합 |
| PT191991256T PT3626731T (pt) | 2014-12-23 | 2015-12-16 | Novos péptidos e combinações de péptidos para uso na imunoterapia contra o carcinoma hepatocelular (chc) e outros cancros |
| PT191991017T PT3626729T (pt) | 2014-12-23 | 2015-12-16 | Novos péptidos e combinações de péptidos para uso na imunoterapia contra o carcinoma hepatocelular (chc) e outros cancros |
| NZ770913A NZ770913A (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| MA41237A MA41237B1 (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaisons de peptides pour une utilisation en immunothérapie contre le carcinome hépatocellulaire (chc) et autres cancers |
| MA49155A MA49155B1 (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
| HRP20211580TT HRP20211580T1 (hr) | 2014-12-23 | 2015-12-16 | Novi peptidi i kombinacije peptida za upotrebu u imunoterpiji protiv hepatocelularnog karcinoma (hcc) i drugih rakova |
| CR20170282A CR20170282A (es) | 2014-12-23 | 2015-12-16 | Nuevos péptidos y nueva combinación de péptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (chc) y otros tipos de cáncer |
| CN202011429041.4A CN112538109A (zh) | 2014-12-23 | 2015-12-16 | 用于肝细胞癌(hcc)和其他癌症免疫治疗的新型肽和肽组合物 |
| BR112017008972-6A BR112017008972A2 (pt) | 2014-12-23 | 2015-12-16 | peptídeos e combinações de peptídeos para uso em imunoterapia contra carcinoma hepatocelular (hcc) e outros cânceres |
| HUE15813809A HUE046641T2 (hu) | 2014-12-23 | 2015-12-16 | Új peptidek és peptidkombinációk hepatocelluláris karcinóma (HCC) és más rákok elleni immunoterápiában történõ alkalmazásra |
| LTEP15813809.9T LT3236985T (lt) | 2014-12-23 | 2015-12-16 | Nauji peptidai ir peptidų deriniai, skirti naudoti imunoterapijai prieš hepatoceliulinę karcinomą (hck) ir kitų rūšių vėžį |
| DK19199098.5T DK3616706T3 (da) | 2014-12-23 | 2015-12-16 | Hidtil ukendte peptider og kombination af peptider til anvendelse ved immunterapi mod hepatocellulært karcinom (hcc) og andre cancere |
| SI201531721T SI3626729T1 (sl) | 2014-12-23 | 2015-12-16 | Novi peptidi in kombinacija peptidov za uporabo v imunoterapiji proti hepatocelularnem karcinomu (HCC) in drugim oblikam raka |
| CN202011432405.4A CN112646021A (zh) | 2014-12-23 | 2015-12-16 | 用于肝细胞癌(hcc)和其他癌症免疫治疗的新型肽和肽组合物 |
| SG11201703322UA SG11201703322UA (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| HUE19199098A HUE057014T2 (hu) | 2014-12-23 | 2015-12-16 | Új peptidek és peptidkombinációk, hepatocelluláris karcinóma (hcc) és más rákok elleni immunoterápiában történõ alkalmazásra |
| KR1020207030041A KR102435015B1 (ko) | 2014-12-23 | 2015-12-16 | 간세포 암종(hcc) 및 기타 암들에 대한 면역요법에서의 사용을 위한 신규 펩티드 및 펩티드의 조합 |
| HRP20192212TT HRP20192212T4 (hr) | 2014-12-23 | 2015-12-16 | Novi peptidi i kombinacije peptida za upotrebu u imunoterapiji protiv hepatocelularnog karcinoma (hcc) i drugih rakova |
| EP19199125.6A EP3626731B1 (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| HRP20211327TT HRP20211327T1 (hr) | 2014-12-23 | 2015-12-16 | Novi peptidi i kombinacije peptida za upotrebu u imunoterapiji protiv hepatocelularnog karcinoma (hcc) i drugih rakova |
| KR1020207015687A KR102395995B1 (ko) | 2014-12-23 | 2015-12-16 | 간세포 암종(hcc) 및 기타 암들에 대한 면역요법에서의 사용을 위한 신규 펩티드 및 펩티드의 조합 |
| EA202190587A EA202190587A3 (ru) | 2014-12-23 | 2015-12-16 | Новые пептиды и комбинации пептидов для применения в иммунотерапии гепатоклеточной карциномы (гкк) и других видов рака |
| ES19199101T ES2896919T3 (es) | 2014-12-23 | 2015-12-16 | Nuevos péptidos y nueva combinación de péptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (CHC) y otros tipos de cáncer |
| DK19199101.7T DK3626729T3 (da) | 2014-12-23 | 2015-12-16 | Hidtil ukendte peptider og kombination af peptider til anvendelse ved immunterapi mod hepatocellulært karcinom (hcc) og andre cancere |
| HRP20211754TT HRP20211754T1 (hr) | 2014-12-23 | 2015-12-16 | Novi peptidi i kombinacije peptida za upotrebu u imunoterapiji protiv hepatocelularnog karcinoma (hcc) i drugih rakova |
| RS20211276A RS62448B1 (sr) | 2014-12-23 | 2015-12-16 | Novi peptidi i kombinacija peptida za upotrebu u imunoterapiji protiv hepatocelularnog karcinoma (hcc) i drugih malignih tumora |
| KR1020247006647A KR20240033128A (ko) | 2014-12-23 | 2015-12-16 | 간세포 암종(hcc) 및 기타 암들에 대한 면역요법에서의 사용을 위한 신규 펩티드 및 펩티드의 조합 |
| SG10202101444UA SG10202101444UA (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| PE2017000542A PE20170940A1 (es) | 2014-12-23 | 2015-12-16 | Nuevos peptidos y nueva combinacion de peptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (chc) y otros tipos de cancer |
| MDE20200300T MD3626731T2 (ro) | 2014-12-23 | 2015-12-16 | Noi peptide și combinație de peptide pentru utilizare în imunoterapie împotriva carcinomului hepatocelular (HCC) și a altor cancere |
| PT191990985T PT3616706T (pt) | 2014-12-23 | 2015-12-16 | Novos péptidos e combinações de péptidos para uso na imunoterapia contra o carcinoma hepatocelular (chc) e outros cancros |
| ES19170191T ES2887107T3 (es) | 2014-12-23 | 2015-12-16 | Nuevos péptidos y nueva combinación de péptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (CHC) y otros tipos de cáncer |
| EP19199114.0A EP3620168A1 (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| UAA201702214A UA124331C2 (uk) | 2014-12-23 | 2015-12-16 | Пептид, здатний зв'язуватися з молекулою головного комплексу гістосумісності (mhc) людини i класу |
| MDE20170224T MD3236985T3 (ro) | 2014-12-23 | 2015-12-16 | Noi peptide și combinații de peptide pentru utilizare în imunoterapie împotriva carcinomului hepatocelular (HCC) și altor tipuri de cancere |
| LTEP19199125.6T LT3626731T (lt) | 2014-12-23 | 2015-12-16 | Nauji peptidai ir peptidų deriniai, skirti naudoti imunoterapijai prieš hepatoceliulinę karcinomą (hck) ir kitų rūšių vėžį |
| ES15813809T ES2763911T5 (es) | 2014-12-23 | 2015-12-16 | Nuevos péptidos y nueva combinación de péptidos para su uso en inmunoterapia contra el carcinoma hepatocelular (CHC) y otros tipos de cáncer |
| CN201580055141.6A CN107001414A (zh) | 2014-12-23 | 2015-12-16 | 用于肝细胞癌(hcc)和其他癌症免疫治疗的新型肽和肽组合物 |
| MYPI2017700826A MY178137A (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| CR20210289A CR20210289A (es) | 2014-12-23 | 2015-12-16 | NUEVOS PÉPTIDOS Y NUEVA COMBINACIÓN DE PÉPTIDOS PARA EL USO EN LA INMUNOTERAPIA CONTRA EL CARCINOMA HEPATOCELULAR (CHC) Y OTROS TIPOS DE CÁNCER (Divisional 2017-282) |
| MA48487A MA48487B1 (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
| RS20211420A RS62575B1 (sr) | 2014-12-23 | 2015-12-16 | Novi peptidi i kombinacija peptida za upotrebu u imunoterapiji protiv hepatocelularnog karcinoma (hcc) i drugih malignih tumora |
| MA46913A MA46913B1 (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
| SI201531025T SI3236985T2 (sl) | 2014-12-23 | 2015-12-16 | Novi peptidi in kombinacija peptidov za uporabo v imunoterapiji proti hepatocelularnem karcinomu (HCC) in drugim oblikam raka |
| MDE20200298T MD3626729T2 (ro) | 2014-12-23 | 2015-12-16 | Noi peptide și combinații de peptide pentru utilizare în imunoterapie împotriva carcinomului hepatocelular (HCC) și a altor cancere |
| HUE19199125A HUE056607T2 (hu) | 2014-12-23 | 2015-12-16 | Új peptidek és peptidkombinációk, hepatocelluláris karcinóma (HCC) és más rákok elleni immunoterápiában történõ alkalmazásra |
| PT191701911T PT3545965T (pt) | 2014-12-23 | 2015-12-16 | Novos péptidos e combinações de péptidos para uso na imunoterapia contra o carcinoma hepatocelular (chc) e outros cancros |
| DK19199125.6T DK3626731T3 (da) | 2014-12-23 | 2015-12-16 | Hidtil ukendte peptider og kombination af peptider til anvendelse ved immunterapi mod hepatocellulært karcinom (hcc) og andre cancere |
| RS20211341A RS62508B1 (sr) | 2014-12-23 | 2015-12-16 | Novi peptidi i kombinacija peptida za upotrebu u imunoterapiji protiv hepatocelularnog karcinoma (hcc) i drugih malignih tumora |
| HRP20211753TT HRP20211753T1 (hr) | 2014-12-23 | 2015-12-16 | Novi peptidi i kombinacije peptida za upotrebu u imunoterapiji protiv hepatocelularnog karcinoma (hcc) i drugih rakova |
| SG10202102698VA SG10202102698VA (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| RS20191606A RS59836B2 (sr) | 2014-12-23 | 2015-12-16 | Novi peptidi i kombinacija peptida za upotrebu u imunoterapiji protiv hepatocelularnog karcinoma (hcc) i drugih malignih tumora |
| ES19199125T ES2899425T3 (es) | 2014-12-23 | 2015-12-16 | Nuevos péptidos y nueva combinación de péptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (CHC) y otros tipos de cáncer |
| PL15813809.9T PL3236985T5 (pl) | 2014-12-23 | 2015-12-16 | Nowe peptydy i kombinacja peptydów do stosowania w immunoterapii przeciwko rakowi wątrobowokomórkowemu (HCC) i innym rodzajom raka |
| LTEP19199101.7T LT3626729T (lt) | 2014-12-23 | 2015-12-16 | Nauji peptidai ir peptidų deriniai, skirti naudoti imunoterapijai prieš hepatoceliulinę karcinomą (hck) ir kitų rūšių vėžį |
| DK19170191.1T DK3545965T3 (da) | 2014-12-23 | 2015-12-16 | Hidtil ukendte peptider og kombination af peptider til anvendelse ved immunterapi mod hepatocellulært karcinom (hcc) og andre cancere |
| MA050819A MA50819A (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
| ES19199098T ES2900106T3 (es) | 2014-12-23 | 2015-12-16 | Nuevos péptidos y nueva combinación de péptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (CHC) y otros tipos de cáncer |
| MA049156A MA49156A (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
| EP19199106.6A EP3626730A1 (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| PL19199098T PL3616706T3 (pl) | 2014-12-23 | 2015-12-16 | Nowe peptydy i kombinacja peptydów do stosowania w immunoterapii względem raka komórek wątroby (HCC) i innych rodzajów raka |
| EP24199595.0A EP4461371A3 (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| EP20172206.3A EP3715357B1 (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| JP2017518096A JP6906156B2 (ja) | 2014-12-23 | 2015-12-16 | 肝細胞がん(hcc)およびその他のがんに対する免疫療法で使用するための新規ペプチドおよびペプチド組み合わせ |
| PCT/EP2015/080018 WO2016102272A1 (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| SI201531736T SI3616706T1 (sl) | 2014-12-23 | 2015-12-16 | Novi peptidi in kombinacija peptidov za uporabo v imunoterapiji proti hepatocelularnem karcinomu (HCC) in drugim oblikam raka |
| MDE20191122T MD3545965T2 (ro) | 2014-12-23 | 2015-12-16 | Noi peptide și combinație de peptide pentru utilizare în imunoterapie împotriva carcinomului hepatocelular (HCC) și a altor cancere |
| RS20211033A RS62237B1 (sr) | 2014-12-23 | 2015-12-16 | Novi peptidi i kombinacija peptida za upotrebu u imunoterapiji protiv hepatocelularnog karcinoma (hcc) i drugih malignih tumora |
| MDE20200241T MD3616706T2 (ro) | 2014-12-23 | 2015-12-16 | Noi peptide și combinație de peptide pentru utilizare în imunoterapie împotriva carcinomului hepatocelular (HCC) și a altor cancere |
| MYPI2021002573A MY199068A (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| EP19170191.1A EP3545965B1 (en) | 2014-12-23 | 2015-12-16 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| FIEP15813809.9T FI3236985T4 (fi) | 2014-12-23 | 2015-12-16 | Uusia peptidejä ja peptidien yhdistelmiä käytettäväksi immunoterapiassa hepatosellulaarista karsinoomaa (hcc) ja muita syöpiä vastaan |
| DK15813809.9T DK3236985T4 (da) | 2014-12-23 | 2015-12-16 | Hidtil ukendte peptider og kombination af peptider til anvendelse ved immunterapi mod hepatocellulært karcinom (hcc) og andre cancere |
| HUE19199101A HUE056087T2 (hu) | 2014-12-23 | 2015-12-16 | Új peptidek és peptidkombinációk a hepatocelluláris karcinóma (HCC) és más daganattípusok immunterápiájában történõ használatra |
| LTEP19170191.1T LT3545965T (lt) | 2014-12-23 | 2015-12-16 | Nauji peptidai ir peptidų deriniai, skirti naudoti imunoterapijai prieš hepatoceliulinę karcinomą (hck) ir kitų rūšių vėžį |
| PL19199101T PL3626729T3 (pl) | 2014-12-23 | 2015-12-16 | Nowe peptydy i kombinacja peptydów do stosowania w immunoterapii względem raka komórek wątroby (hcc) i innych rodzajów raka |
| HUE19170191A HUE055489T2 (hu) | 2014-12-23 | 2015-12-16 | Új peptidek és peptidkombinációk a hepatocelluláris karcinóma (HCC) és más daganattípusok immunoterápiájában történõ használatra |
| TW112102743A TW202321273A (zh) | 2014-12-23 | 2015-12-21 | 用於肝細胞癌(hcc)和其他癌症免疫治療的新型肽和肽組合物 |
| TW109103806A TWI754892B (zh) | 2014-12-23 | 2015-12-21 | 用於肝細胞癌(hcc)和其他癌症免疫治療的新型肽和肽組合物 |
| TW104142988A TWI687436B (zh) | 2014-12-23 | 2015-12-21 | 用於肝細胞癌(hcc)和其他癌症免疫治療的新型肽和肽組合物 |
| US14/975,952 US10064926B2 (en) | 2014-12-23 | 2015-12-21 | Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| TW109139864A TWI794679B (zh) | 2014-12-23 | 2015-12-21 | 用於肝細胞癌(hcc)和其他癌症免疫治療的新型肽和肽組合物 |
| US15/357,757 US20170080070A1 (en) | 2014-12-23 | 2016-11-21 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| IL250989A IL250989B (en) | 2014-12-23 | 2017-03-07 | New peptides and a combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other types of cancer |
| ZA2017/01762A ZA201701762B (en) | 2014-12-23 | 2017-03-10 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| CONC2017/0003772A CO2017003772A2 (es) | 2014-12-23 | 2017-04-19 | Péptidos y combinación de péptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (chc) y otros tipos de cáncer |
| CL2017001391A CL2017001391A1 (es) | 2014-12-23 | 2017-05-31 | Nuevos péptidos y nueva combinación de péptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (chc) y otros tipos de cáncer |
| MX2020011793A MX2020011793A (es) | 2014-12-23 | 2017-06-21 | Nuevos peptidos y nueva combinacion de peptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (chc) y otros tipos de cancer. |
| MX2020004757A MX2020004757A (es) | 2014-12-23 | 2017-06-21 | Nuevos peptidos y nueva combinacion de peptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (chc) y otros tipos de cancer. |
| MX2020011787A MX2020011787A (es) | 2014-12-23 | 2017-06-21 | Nuevos peptidos y nueva combinacion de peptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (chc) y otros tipos de cancer. |
| MX2020005188A MX2020005188A (es) | 2014-12-23 | 2017-06-21 | Nuevos peptidos y nueva combinacion de peptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (chc) y otros tipos de cancer. |
| MX2020011791A MX2020011791A (es) | 2014-12-23 | 2017-06-21 | Nuevos peptidos y nueva combinacion de peptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (chc) y otros tipos de cancer. |
| MX2020011794A MX2020011794A (es) | 2014-12-23 | 2017-06-21 | Nuevos peptidos y nueva combinacion de peptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (chc) y otros tipos de cancer. |
| US15/917,098 US20180207252A1 (en) | 2014-12-23 | 2018-03-09 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| US15/918,788 US11406693B2 (en) | 2014-12-23 | 2018-03-12 | Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| US16/134,422 US20190000947A1 (en) | 2014-12-23 | 2018-09-18 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| CY20191101328T CY1122491T1 (el) | 2014-12-23 | 2019-12-17 | Καινοτομα πεπτιδια και συνδυασμος πεπτιδιων για χρηση στην ανοσοθεραπεια εναντι του ηπατοκυτταρικου καρκινωματος (hcc) και αλλων καρκινων |
| JP2020102005A JP7358299B2 (ja) | 2014-12-23 | 2020-06-12 | 肝細胞がん(hcc)およびその他のがんに対する免疫療法で使用するための新規ペプチドおよびペプチド組み合わせ |
| JP2020102006A JP2020191866A (ja) | 2014-12-23 | 2020-06-12 | 肝細胞がん(hcc)およびその他のがんに対する免疫療法で使用するための新規ペプチドおよびペプチド組み合わせ |
| JP2020102004A JP7109801B2 (ja) | 2014-12-23 | 2020-06-12 | 肝細胞がん(hcc)およびその他のがんに対する免疫療法で使用するための新規ペプチドおよびペプチド組み合わせ |
| JP2020102991A JP2020191867A (ja) | 2014-12-23 | 2020-06-15 | 肝細胞がん(hcc)およびその他のがんに対する免疫療法で使用するための新規ペプチドおよびペプチド組み合わせ |
| JP2020102993A JP7448423B2 (ja) | 2014-12-23 | 2020-06-15 | 肝細胞がん(hcc)およびその他のがんに対する免疫療法で使用するための新規ペプチドおよびペプチド組み合わせ |
| JP2020102992A JP7346361B2 (ja) | 2014-12-23 | 2020-06-15 | 肝細胞がん(hcc)およびその他のがんに対する免疫療法で使用するための新規ペプチドおよびペプチド組み合わせ |
| JP2020106475A JP7026411B2 (ja) | 2014-12-23 | 2020-06-19 | 肝細胞がん(hcc)およびその他のがんに対する免疫療法で使用するための新規ペプチドおよびペプチド組み合わせ |
| US16/915,308 US20200376103A1 (en) | 2014-12-23 | 2020-06-29 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| AU2020213294A AU2020213294B2 (en) | 2014-12-23 | 2020-08-04 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| AU2020213295A AU2020213295B2 (en) | 2014-12-23 | 2020-08-04 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| US17/018,915 US20200405831A1 (en) | 2014-12-23 | 2020-09-11 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| IL281752A IL281752A (en) | 2014-12-23 | 2021-03-23 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| JP2021052978A JP7713309B2 (ja) | 2014-12-23 | 2021-03-26 | 肝細胞がん(hcc)およびその他のがんに対する免疫療法で使用するための新規ペプチドおよびペプチド組み合わせ |
| US17/245,918 US11786583B2 (en) | 2014-12-23 | 2021-04-30 | Peptides and combination of peptides for use in immunotherapy against Hepatocellular carcinoma (HCC) and other cancers |
| CL2021001479A CL2021001479A1 (es) | 2014-12-23 | 2021-06-04 | Péptido; uso de composiciones; composición farmacéutica; uso de un anticuerpo para terapia; uso de un anticuerpo para elisa, inmunohistoquímica y/o formación de imágenes; receptor de linfocito t; y uso de un linfocito t citotóxico activado (divisional de la solicitud n° 201701391) |
| US17/492,112 US12076380B2 (en) | 2014-12-23 | 2021-10-01 | Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| CY20211100869T CY1124533T1 (el) | 2014-12-23 | 2021-10-06 | Καινοτομα πεπτιδια και συνδυασμος πεπτιδιων για χρηση στην ανοσοθεραπεια εναντι του ηπατοκυτταρικου καρκινωματος (hcc) και αλλων καρκινων |
| US17/502,170 US12070491B2 (en) | 2014-12-23 | 2021-10-15 | Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| US17/502,185 US12121572B2 (en) | 2014-12-23 | 2021-10-15 | Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| US17/508,230 US12097248B2 (en) | 2014-12-23 | 2021-10-22 | Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| US17/508,295 US20220054613A1 (en) | 2014-12-23 | 2021-10-22 | Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| US17/516,304 US11576956B2 (en) | 2014-12-23 | 2021-11-01 | Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| CY20211101071T CY1124847T1 (el) | 2014-12-23 | 2021-12-07 | Καινοτομα πεπτιδια και συνδυασμος πεπτιδιων για χρηση στην ανοσοθεραπεια εναντι του ηπατοκυτταρικου καρκινωματος (hcc) και αλλων καρκινων |
| CY20211101070T CY1124846T1 (el) | 2014-12-23 | 2021-12-07 | Καινοτομα πεπτιδια και συνδυασμος πεπτιδιων για χρηση στην ανοσοθεραπεια εναντι του ηπατοκυτταρικου καρκινωματος (hcc) και αλλων καρκινων |
| CY20211101104T CY1124813T1 (el) | 2014-12-23 | 2021-12-15 | Καινοτομα πεπτιδια και συνδυασμος πεπτιδιων για χρηση στην ανοσοθεραπεια εναντι του ηπατοκυτταρικου καρκινωματος (hcc) και αλλων μορφων καρκινου |
| US17/728,756 US11559573B2 (en) | 2014-12-23 | 2022-04-25 | Method of eliciting a CD8+ cytotoxic response in hepatocellular carcinoma patients with a population of activated T cells |
| US17/853,344 US11679147B2 (en) | 2014-12-23 | 2022-06-29 | Method of eliciting a CD8+ cytotoxic response in hepatocellular carcinoma patients with a population of activated T cells |
| US17/853,334 US11779638B2 (en) | 2014-12-23 | 2022-06-29 | Method of eliciting a CD8+ cytotoxic response in hepatocellular carcinoma patients with a population of activated T cells |
| US17/852,623 US11672848B2 (en) | 2014-12-23 | 2022-06-29 | Method of eliciting a CD8+ cytotoxic response in hepatocellular carcinoma patients with a population of activated T cells |
| AU2022268329A AU2022268329A1 (en) | 2014-12-23 | 2022-11-09 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| JP2023078113A JP2023100927A (ja) | 2014-12-23 | 2023-05-10 | 肝細胞がん(hcc)およびその他のがんに対する免疫療法で使用するための新規ペプチドおよびペプチド組み合わせ |
| US18/814,073 US20240408166A1 (en) | 2014-12-23 | 2024-08-23 | Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
| JP2025098413A JP2025134788A (ja) | 2014-12-23 | 2025-06-12 | 肝細胞がん(hcc)およびその他のがんに対する免疫療法で使用するための新規ペプチドおよびペプチド組み合わせ |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462096165P | 2014-12-23 | 2014-12-23 | |
| GB201423016 | 2014-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB201501017D0 true GB201501017D0 (en) | 2015-03-04 |
Family
ID=52630910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB1501017.6A Ceased GB201501017D0 (en) | 2014-12-23 | 2015-01-21 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
Country Status (25)
| Country | Link |
|---|---|
| US (8) | US10064926B2 (enExample) |
| EP (8) | EP3626729B1 (enExample) |
| JP (2) | JP6906156B2 (enExample) |
| KR (1) | KR102284493B1 (enExample) |
| CN (4) | CN112646025A (enExample) |
| AR (2) | AR103220A1 (enExample) |
| AU (3) | AU2015371490B2 (enExample) |
| BR (1) | BR112017008972A2 (enExample) |
| CA (1) | CA2972126A1 (enExample) |
| CL (1) | CL2017001391A1 (enExample) |
| CR (1) | CR20170282A (enExample) |
| DK (4) | DK3626729T3 (enExample) |
| EA (2) | EA201791150A1 (enExample) |
| GB (1) | GB201501017D0 (enExample) |
| IL (1) | IL250989B (enExample) |
| MA (3) | MA40136A1 (enExample) |
| MX (1) | MX377144B (enExample) |
| PE (1) | PE20170940A1 (enExample) |
| PH (1) | PH12017500484B1 (enExample) |
| PL (1) | PL3236985T5 (enExample) |
| RS (4) | RS62448B1 (enExample) |
| SG (1) | SG11201703322UA (enExample) |
| SI (3) | SI3236985T2 (enExample) |
| TW (1) | TWI687436B (enExample) |
| WO (1) | WO2016102272A1 (enExample) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9458450B2 (en) | 2012-03-15 | 2016-10-04 | Flodesign Sonics, Inc. | Acoustophoretic separation technology using multi-dimensional standing waves |
| US9950282B2 (en) | 2012-03-15 | 2018-04-24 | Flodesign Sonics, Inc. | Electronic configuration and control for acoustic standing wave generation |
| US10967298B2 (en) | 2012-03-15 | 2021-04-06 | Flodesign Sonics, Inc. | Driver and control for variable impedence load |
| US10322949B2 (en) | 2012-03-15 | 2019-06-18 | Flodesign Sonics, Inc. | Transducer and reflector configurations for an acoustophoretic device |
| US9745548B2 (en) | 2012-03-15 | 2017-08-29 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US10689609B2 (en) | 2012-03-15 | 2020-06-23 | Flodesign Sonics, Inc. | Acoustic bioreactor processes |
| US9752113B2 (en) | 2012-03-15 | 2017-09-05 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US10737953B2 (en) | 2012-04-20 | 2020-08-11 | Flodesign Sonics, Inc. | Acoustophoretic method for use in bioreactors |
| US9745569B2 (en) | 2013-09-13 | 2017-08-29 | Flodesign Sonics, Inc. | System for generating high concentration factors for low cell density suspensions |
| WO2015105955A1 (en) | 2014-01-08 | 2015-07-16 | Flodesign Sonics, Inc. | Acoustophoresis device with dual acoustophoretic chamber |
| JP7025119B2 (ja) * | 2014-04-24 | 2022-02-24 | ロード アイランド ホスピタル | アスパラギン酸-β-ヒドロキシラーゼは腫瘍においてエピトープ特異的T細胞応答を誘導する |
| US9744483B2 (en) | 2014-07-02 | 2017-08-29 | Flodesign Sonics, Inc. | Large scale acoustic separation device |
| HRP20192212T4 (hr) | 2014-12-23 | 2022-11-25 | Immatics Biotechnologies Gmbh | Novi peptidi i kombinacije peptida za upotrebu u imunoterapiji protiv hepatocelularnog karcinoma (hcc) i drugih rakova |
| GB201501017D0 (en) | 2014-12-23 | 2015-03-04 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| PE20171307A1 (es) | 2014-12-23 | 2017-09-05 | Novartis Ag | Compuestos de triazolopirimidina y usos de los mismos |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11021699B2 (en) | 2015-04-29 | 2021-06-01 | FioDesign Sonics, Inc. | Separation using angled acoustic waves |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11459540B2 (en) | 2015-07-28 | 2022-10-04 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11474085B2 (en) | 2015-07-28 | 2022-10-18 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| MY198087A (en) | 2015-10-05 | 2023-07-31 | Immatics Biotechnologies Gmbh | Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers |
| US11020429B2 (en) | 2015-11-05 | 2021-06-01 | Juno Therapeutics, Inc. | Vectors and genetically engineered immune cells expressing metabolic pathway modulators and uses in adoptive cell therapy |
| MX2018007204A (es) | 2015-12-16 | 2018-12-11 | Gritstone Oncology Inc | Identificacion, fabricacion y uso de neoantigeno. |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| US11085035B2 (en) | 2016-05-03 | 2021-08-10 | Flodesign Sonics, Inc. | Therapeutic cell washing, concentration, and separation utilizing acoustophoresis |
| GB201609193D0 (en) | 2016-05-25 | 2016-07-06 | Immatics Biotechnologies Gmbh | Novel peptides, combination of peptides as targets for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers |
| JP7075125B2 (ja) | 2016-05-25 | 2022-05-25 | イマティクス バイオテクノロジーズ ゲーエムベーハー | 標的としてのおよび胆嚢がんおよび胆管がんおよびその他のがんに対する免疫療法で使用するための新規ペプチド、ペプチド組み合わせ |
| KR102519922B1 (ko) | 2016-06-20 | 2023-04-11 | 노파르티스 아게 | 트리아졸로피리미딘 화합물의 결정질 형태 |
| WO2017221100A1 (en) | 2016-06-20 | 2017-12-28 | Novartis Ag | Imidazopyrimidine compounds useful for the treatment of cancer |
| EP3472161B1 (en) | 2016-06-20 | 2020-03-25 | Novartis AG | Triazolopyridine compounds and uses thereof |
| PT3522905T (pt) | 2016-10-07 | 2024-10-02 | Io Biotech Aps | Péptidos de arginase imunogénicos |
| JP2020513248A (ja) | 2016-10-19 | 2020-05-14 | フロデザイン ソニックス, インク.Flodesign Sonics, Inc. | 音響による親和性細胞抽出 |
| DE102016123893A1 (de) | 2016-12-08 | 2018-06-14 | Immatics Biotechnologies Gmbh | T-Zellrezeptoren mit verbesserter Bindung |
| KR102639592B1 (ko) | 2016-12-08 | 2024-02-21 | 이매틱스 바이오테크놀로지스 게엠베하 | 짝짓기가 향상된 t 세포 수용체 |
| CR20210128A (es) * | 2017-01-27 | 2021-04-26 | Immatics Biotechnologies Gmbh | Nuevos péptidos y nuevas combinaciones de péptidos para el uso en la inmunoterapia contra el cáncer de ovario y otros tipos de cancer (divisional exp. 2019-388) |
| EP3638695A4 (en) * | 2017-06-14 | 2021-06-30 | Icahn School of Medicine at Mount Sinai | METHOD OF DETECTION AND TREATMENT OF IMMUNOTHERAPY-RESPONDING CLASSES OF HEPATOCELLULAR CARCINOMA |
| DE102017115966A1 (de) | 2017-07-14 | 2019-01-17 | Immatics Biotechnologies Gmbh | Polypeptidmolekül mit verbesserter zweifacher Spezifität |
| ES2898210T3 (es) | 2017-07-14 | 2022-03-04 | Immatics Biotechnologies Gmbh | Molécula de polipéptido con especificidad dual mejorada |
| EP3665301B1 (en) * | 2017-08-09 | 2023-10-04 | PamGene B.V. | Method for predicting the response of non-small-cell lung carcinoma patients to a medicament |
| GB201713700D0 (en) * | 2017-08-25 | 2017-10-11 | Anastasis Biotec Ltd | Peptide conjugates |
| AU2018348165B2 (en) | 2017-10-10 | 2025-09-04 | Seattle Project Corp. | Neoantigen identification using hotspots |
| US11885815B2 (en) | 2017-11-22 | 2024-01-30 | Gritstone Bio, Inc. | Reducing junction epitope presentation for neoantigens |
| BR112020009889A2 (pt) | 2017-12-14 | 2020-11-03 | Flodesign Sonics, Inc. | acionador e controlador de transdutor acústico |
| JP2021517810A (ja) * | 2018-03-12 | 2021-07-29 | ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアThe Children’S Hospital Of Philadelphia | 養子免疫療法における腫瘍自己抗原の使用のための方法および組成物 |
| EP3802568A4 (en) | 2018-06-08 | 2022-07-13 | The Board of Regents of the University of Oklahoma | PEPTIDE THERAPEUTICS USED TO TREAT ALZHEIMER'S DISEASE AND RELATED DISEASES |
| DE102018122546B3 (de) * | 2018-09-14 | 2019-12-05 | Immatics Biotechnologies Gmbh | Verfahren zum Hochdurchsatz-Peptid-MHC-Affinitätsscreening für TCR-Liganden |
| GB201815549D0 (en) | 2018-09-24 | 2018-11-07 | Io Biotech Aps | Arginase1 polypeptides |
| WO2020084621A1 (en) * | 2018-10-26 | 2020-04-30 | Tami Bar | Compositions and methods for biodegrading alcohol |
| CN109663128A (zh) * | 2018-11-21 | 2019-04-23 | 中国农业大学 | 一种肺动脉高压标志物及其作为治疗靶点的应用 |
| EP3893925A4 (en) * | 2018-12-13 | 2023-01-18 | Rhode Island Hospital | INHIBITING THE GROWTH AND DEVELOPMENT OF ASPH-EXPRESSING TUMORS |
| EP3721899A1 (en) | 2019-04-08 | 2020-10-14 | China Medical University | Combination therapies comprising dendritic cells-based vaccine and immune checkpoint inhibitor |
| CN110850086B (zh) * | 2019-11-18 | 2023-05-02 | 西安交通大学 | 一种肝移植术后缺血性胆道病变血清诊断标志物acly的应用 |
| CN113461798A (zh) * | 2020-03-18 | 2021-10-01 | 北京鼎成肽源生物技术有限公司 | 一种输卵管癌靶标抗原、输卵管癌靶标抗原刺激培养的ctl细胞及其应用 |
| US20230287505A1 (en) * | 2020-03-30 | 2023-09-14 | Rophelbio Co., Ltd. | Biomarker for cancer immunotherapy and use thereof |
| EP4153633A1 (en) | 2020-05-19 | 2023-03-29 | Amgen Inc. | Mageb2 binding constructs |
| CN115975943A (zh) * | 2020-07-14 | 2023-04-18 | 广州泛恩生物科技有限公司 | 基于acp5阳性t细胞的用于杀伤肿瘤的tcr-t细胞及其制备方法和应用 |
| CN112063718A (zh) * | 2020-09-18 | 2020-12-11 | 中国医科大学 | Usp14在肝细胞肝癌诊断、预后判断以及治疗中的应用 |
| CN112043722B (zh) * | 2020-09-25 | 2022-02-15 | 中国医科大学 | Prpf6在前列腺癌及去势抵抗前列腺癌治疗中的应用 |
| CN114574486B (zh) * | 2020-12-01 | 2024-04-16 | 中国科学院大连化学物理研究所 | 作用于OPLAH的siRNA、DNA及构建物和应用 |
| CN114163512B (zh) * | 2021-03-24 | 2025-02-25 | 深圳市新靶向生物科技有限公司 | 一种与肝癌驱动基因突变相关的抗原肽组合及其应用 |
| WO2022212831A1 (en) | 2021-04-02 | 2022-10-06 | Amgen Inc. | Mageb2 binding constructs |
| US20250084159A1 (en) * | 2021-07-19 | 2025-03-13 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Mct11 antibodies to treat t cell functional exhaustion and enhance cancer immunotherapy |
| CN115634281B (zh) * | 2021-07-20 | 2025-12-02 | 肖伯端 | Ctrp3蛋白的抗瘤作用及编码其的重组溶瘤病毒及制备方法和应用 |
| CN113502300B (zh) * | 2021-07-21 | 2024-02-06 | 徐州医科大学 | 一种含有hdac10基因启动子序列和报告基因的重组质粒、制备方法及应用 |
| EP4419548A4 (en) * | 2021-10-18 | 2025-12-17 | Univ Texas | PEPTIDES AND MANIPULATED T-CELL RECEPTORS FOR TARGETTING NDC80 ANTIGEN AND METHOD FOR USE |
| CN115572764B (zh) * | 2022-03-30 | 2024-06-21 | 江苏鹍远生物技术有限公司 | 一组肿瘤检测标志物及其用途 |
| CN116334031A (zh) * | 2022-07-21 | 2023-06-27 | 中国人民解放军陆军军医大学 | 三个多肽及其在制备ⅰ型糖尿病免疫防治疫苗或药物中的应用 |
| CN116042825B (zh) * | 2022-09-28 | 2025-07-01 | 南方医科大学 | 一种评估5-fu治疗胃癌癌敏感性的探针引物组及其试剂盒 |
| WO2024235848A1 (en) * | 2023-05-12 | 2024-11-21 | Fundación Para La Investigación Médica Aplicada | Novel t cell receptors |
| WO2025021979A1 (en) | 2023-07-27 | 2025-01-30 | Immatics Biotechnologies Gmbh | Novel t cell receptors targeting melanoma-associated antigen (mage) b2 and immune therapy using the same |
| TW202506719A (zh) | 2023-07-27 | 2025-02-16 | 德商艾瑪提克生物技術有限公司 | 針對mageb2之抗原結合蛋白 |
| CN119524137A (zh) * | 2024-12-11 | 2025-02-28 | 徐州医科大学 | Fbxo22在诊断、治疗非酒精性脂肪性肝病中的应用 |
Family Cites Families (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4440859A (en) | 1977-05-27 | 1984-04-03 | The Regents Of The University Of California | Method for producing recombinant bacterial plasmids containing the coding sequences of higher organisms |
| US4704362A (en) | 1977-11-08 | 1987-11-03 | Genentech, Inc. | Recombinant cloning vehicle microbial polypeptide expression |
| IE53176B1 (en) | 1978-12-22 | 1988-08-17 | Biogen Nv | Recombinant dna molecules and their method of production |
| US4530901A (en) | 1980-01-08 | 1985-07-23 | Biogen N.V. | Recombinant DNA molecules and their use in producing human interferon-like polypeptides |
| US4342566A (en) | 1980-02-22 | 1982-08-03 | Scripps Clinic & Research Foundation | Solid phase anti-C3 assay for detection of immune complexes |
| US4678751A (en) | 1981-09-25 | 1987-07-07 | Genentech, Inc. | Hybrid human leukocyte interferons |
| US4766075A (en) | 1982-07-14 | 1988-08-23 | Genentech, Inc. | Human tissue plasminogen activator |
| US4582800A (en) | 1982-07-12 | 1986-04-15 | Hoffmann-La Roche Inc. | Novel vectors and method for controlling interferon expression |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4757006A (en) | 1983-10-28 | 1988-07-12 | Genetics Institute, Inc. | Human factor VIII:C gene and recombinant methods for production |
| US4677063A (en) | 1985-05-02 | 1987-06-30 | Cetus Corporation | Human tumor necrosis factor |
| US4810648A (en) | 1986-01-08 | 1989-03-07 | Rhone Poulenc Agrochimie | Haloarylnitrile degrading gene, its use, and cells containing the gene |
| US4897445A (en) | 1986-06-27 | 1990-01-30 | The Administrators Of The Tulane Educational Fund | Method for synthesizing a peptide containing a non-peptide bond |
| ATE157100T1 (de) | 1993-06-03 | 1997-09-15 | Therapeutic Antibodies Inc | Antikoerperfragmente in therapie |
| AUPM322393A0 (en) | 1993-12-24 | 1994-01-27 | Austin Research Institute, The | Mucin carbohydrate compounds and their use in immunotherapy |
| DE69723230T2 (de) | 1996-01-17 | 2004-05-27 | Imperial College Innovations Ltd. | Immunotherapie mit verwendung von zytotoxischen t lymphozyten (ctl) |
| US5849589A (en) | 1996-03-11 | 1998-12-15 | Duke University | Culturing monocytes with IL-4, TNF-α and GM-CSF TO induce differentiation to dendric cells |
| US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| WO2001044279A2 (en) * | 1999-12-17 | 2001-06-21 | Chiron Corporation | Mammalian dishevelled-associated proteins |
| EP1259601A2 (en) | 2000-02-22 | 2002-11-27 | Ahuva Nissim | Chimeric and tcr phage display libraries, chimeric and tcr reagents and methods of use thereof |
| US20040191260A1 (en) | 2003-03-26 | 2004-09-30 | Technion Research & Development Foundation Ltd. | Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof |
| AU785493B2 (en) | 2000-03-27 | 2008-01-03 | Technion Research & Development Foundation Ltd. | Single chain class I major histo-compatibility complexes, constructs encoding same and methods of generating same |
| CN101712721A (zh) | 2000-06-05 | 2010-05-26 | 阿尔托生物科学有限公司 | T细胞受体融合物及共轭物以及其使用方法 |
| US20020048550A1 (en) | 2000-07-20 | 2002-04-25 | Vallera Daniel A. | Radiolabeled immunotoxins |
| US20050053918A1 (en) | 2001-05-16 | 2005-03-10 | Technion Research & Development Foundation Ltd. | Method of identifying peptides capable of binding to MHC molecules, peptides identified thereby and their uses |
| US6867283B2 (en) | 2001-05-16 | 2005-03-15 | Technion Research & Development Foundation Ltd. | Peptides capable of binding to MHC molecules, cells presenting such peptides, and pharmaceutical compositions comprising such peptides and/or cells |
| US6992176B2 (en) | 2002-02-13 | 2006-01-31 | Technion Research & Development Foundation Ltd. | Antibody having a T-cell receptor-like specificity, yet higher affinity, and the use of same in the detection and treatment of cancer, viral infection and autoimmune disease |
| WO2003070752A2 (en) | 2002-02-20 | 2003-08-28 | Dyax Corporation | Mhc-peptide complex binding ligands |
| US7311914B2 (en) | 2002-08-13 | 2007-12-25 | Ludwig Institute For Cancer Research | MAGE-A4 antigenic peptides and uses thereof |
| WO2004018667A1 (ja) * | 2002-08-26 | 2004-03-04 | Kirin Beer Kabushiki Kaisha | ペプチド及びこれを含む医薬 |
| WO2004033685A1 (en) | 2002-10-09 | 2004-04-22 | Avidex Ltd | Single chain recombinant t cell receptors |
| NZ570811A (en) | 2002-11-09 | 2009-11-27 | Immunocore Ltd | T cell receptor display |
| US20040096982A1 (en) | 2002-11-19 | 2004-05-20 | International Business Machines Corporation | Methods and apparatus for analysis of mass spectra |
| DE602004015064D1 (de) * | 2003-01-06 | 2008-08-28 | Wyeth Corp | Zusammensetzungen und verfahren zur diagnose und behandlung von kolonkrebs |
| GB0304068D0 (en) | 2003-02-22 | 2003-03-26 | Avidex Ltd | Substances |
| US20090075304A1 (en) | 2004-05-27 | 2009-03-19 | Weidanz Jon A | Methods of assaying vaccine potency |
| US20090304679A1 (en) | 2004-05-27 | 2009-12-10 | Weidanz Jon A | Antibodies as T cell receptor mimics, methods of production and uses thereof |
| US20090233318A1 (en) | 2004-12-28 | 2009-09-17 | Weidanz Jon A | Methods of assaying vaccine potency |
| DE602005020046D1 (de) | 2005-09-05 | 2010-04-29 | Immatics Biotechnologies Gmbh | Tumor-assoziierte Peptide, welche an unterschiedliche menschliche Leukozytenantigene der Klasse II binden |
| SI1760089T1 (sl) * | 2005-09-05 | 2009-12-31 | Immatics Biotechnologies Gmbh | S tumorjem povezani peptidi, ki se veĹľejo na molekule humanega levkocitnega antigena (HLA) razreda I ali II in ustrezno cepivo proti raku |
| AU2007284651B2 (en) | 2006-08-09 | 2014-03-20 | Institute For Systems Biology | Organ-specific proteins and methods of their use |
| JP5352586B2 (ja) * | 2007-07-27 | 2013-11-27 | イマティクス バイオテクノロジーズ ゲーエムベーハー | 腫瘍関連ペプチドおよび関連抗癌ワクチンの組成物 |
| PL2183361T3 (pl) * | 2007-07-27 | 2015-10-30 | Immatics Biotechnologies Gmbh | Innowacyjna immunoterapia przeciwko nowotworom mózgu |
| WO2009026547A1 (en) | 2007-08-22 | 2009-02-26 | Receptor Logi, Ltd. | Methods of assaying vaccine potency |
| PL2201100T3 (pl) * | 2007-09-14 | 2016-10-31 | Wzmacnianie zdolności ludzkich komórek prezentujących antygen do stymulacji komórek T i ich zastosowanie w szczepieniu | |
| WO2009108372A2 (en) * | 2008-02-27 | 2009-09-03 | Receptor Logic, Inc. | Antibodies as t cell receptor mimics, methods of production and uses thereof |
| HUE028261T2 (en) * | 2008-03-27 | 2016-12-28 | Immatics Biotechnologies Gmbh | New immunotherapy for neuronal and brain tumors |
| US20090263574A1 (en) | 2008-04-21 | 2009-10-22 | Quinn Daniel E | Method of restoring an article |
| WO2009151487A1 (en) * | 2008-06-13 | 2009-12-17 | Receptor Logic, Inc. | Methods of assaying vaccine potency |
| DE102008049136B4 (de) | 2008-09-26 | 2012-10-25 | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. | Neue Regulatoren des angeborenen Immunsystems |
| RS53782B1 (sr) * | 2008-10-01 | 2015-06-30 | Immatics Biotechnologies Gmbh | Preparati tumor-asociranih peptida i odgovarajuća antikancerska vakcina za tretman glioblastoma (gbm) i drugih kancera |
| EP2499488A1 (en) | 2009-11-14 | 2012-09-19 | Kuang-Yuh Chyu | Immunomodulatory methods and systems for treatment and/or prevention of atherosclerosis |
| US8506964B2 (en) | 2010-02-05 | 2013-08-13 | Cardiovax, Llc | Fusion proteins and related compositions, methods and systems for treatment and/or prevention of atherosclerosis |
| GB201006360D0 (en) | 2010-04-16 | 2010-06-02 | Immatics Biotechnologies Gmbh | Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development |
| CA2816225A1 (en) | 2010-10-26 | 2012-05-03 | Technion Research & Development Foundation Ltd. | Antibodies which bind soluble t-cell receptor ligands |
| JP2013544243A (ja) | 2010-11-12 | 2013-12-12 | シーダース シナイ メディカル センター | 動脈瘤の治療及び/又は予防のための免疫調節方法及びシステム |
| RU2013126888A (ru) | 2010-11-12 | 2014-12-20 | Седарс-Синаи Медикал Сентер | ИММУНОМОДУЛИРУЮЩИЕ КОМПОЗИЦИИ, СПОСОБЫ И СИСТЕМЫ, СОДЕРЖАЩИЕ ИММУНОГЕННЫЕ ФРАГМЕНТЫ АроВ100 |
| US9205141B2 (en) | 2010-11-12 | 2015-12-08 | Cardio Vax, Llc | Immunomodulatory methods and systems for treatment and/or prevention of hypertension |
| WO2013057586A1 (en) | 2011-10-19 | 2013-04-25 | Oslo Universitetssykehus Hf | Compositions and methods for producing soluble t - cell receptors |
| EP2788012A4 (en) * | 2011-11-11 | 2015-08-05 | Cedars Sinai Medical Center | COMPOSITIONS AND METHODS OF TREATING NURSE DISEASES |
| GB201208293D0 (en) * | 2012-05-11 | 2012-06-20 | Circassia Ltd | Hydrochlorice salt of peptide |
| CA2883673A1 (en) * | 2012-09-05 | 2014-03-13 | University Of Virginia Patent Foundation | Target peptides for colorectal cancer therapy and diagnostics |
| US20190292535A1 (en) | 2012-11-08 | 2019-09-26 | Roche Diagnostics Operations, Inc. | Nucleic acids encoding chimeric polypeptides for library screening |
| GB201301632D0 (en) * | 2013-01-30 | 2013-03-13 | Imp Innovations | Complement System |
| US9134326B2 (en) * | 2013-03-14 | 2015-09-15 | Battelle Memorial Institute | Biomarkers for liver fibrosis |
| EP2808392A1 (en) | 2013-05-28 | 2014-12-03 | Rheinische Friedrich-Wilhelms-Universität Bonn | Aptamers and use of the aptamers in the diagnosis and treatment of cancer |
| CN103739667B (zh) * | 2013-09-24 | 2017-08-25 | 上海宇研生物技术有限公司 | 卵巢癌特异的肿瘤抗原肽及其制备方法 |
| CA2942433C (en) | 2014-03-14 | 2023-08-01 | Immunocore Limited | Tcr libraries |
| GB201501017D0 (en) | 2014-12-23 | 2015-03-04 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| GB201507719D0 (en) * | 2015-05-06 | 2015-06-17 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds thereof for use in immunotherapy against colorectal carcinoma (CRC) and other cancers |
| NL2014935B1 (en) | 2015-06-08 | 2017-02-03 | Applied Immune Tech Ltd | T cell receptor like antibodies having fine specificity. |
| US20180179283A1 (en) | 2015-06-08 | 2018-06-28 | Adicet Bio Inc. | T cell receptor like antibodies having fine specificity |
| SI3440106T1 (sl) | 2016-04-08 | 2022-02-28 | Adaptimmune Limited | T-celični receptorji |
| JP7204484B2 (ja) | 2016-04-08 | 2023-01-16 | アダプティミューン・リミテッド | T細胞受容体 |
| EP3440102B1 (en) | 2016-04-08 | 2024-06-05 | Adaptimmune Limited | T cell receptors |
| EP3491856B1 (en) | 2016-07-27 | 2025-09-17 | Sharp Kabushiki Kaisha | Wireless telecommuncations methods and apparatus using system information value tag |
| US20200325244A1 (en) | 2020-05-18 | 2020-10-15 | Abexxa Biologics, Inc. | Antibodies and methods of use thereof |
| EP3573997A4 (en) | 2017-01-24 | 2020-12-09 | Abexxa Biologics, Inc. | METHODS AND COMPOSITIONS INTENDED TO TARGE A COMPLEX INCLUDING A NON-CLASSIC HLA-I AND A NEO-ANTIGEN IN THE TREATMENT OF CANCER |
| EP3636761B1 (en) | 2017-06-05 | 2024-07-31 | Mie University | Antigen-binding protein recognizing mage-a4-derived peptide |
| SG11201911430PA (en) | 2017-07-04 | 2020-01-30 | Curevac Ag | Novel nucleic acid molecules |
| WO2019036688A1 (en) | 2017-08-18 | 2019-02-21 | Gritstone Oncology, Inc. | ANTIGEN BINDING PROTEINS TARGETING SHARED ANTIGENS |
| WO2019051001A1 (en) | 2017-09-06 | 2019-03-14 | California Institute Of Technology | SIGNALING AND BIFUNCTIONAL RECEPTORS HAVING ANTIGENS (SABR) |
| CA3086923A1 (en) | 2017-12-28 | 2019-07-04 | Gritstone Oncology, Inc. | Antigen-binding proteins targeting shared antigens |
| JP7469807B2 (ja) | 2018-04-19 | 2024-04-17 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | Mage-b2特異性を有するt細胞受容体およびその使用 |
| TW202000907A (zh) | 2018-05-23 | 2020-01-01 | 美商葛利史東腫瘤科技公司 | 共有抗原 |
| US20200291128A1 (en) | 2020-05-18 | 2020-09-17 | Abexxa Biologics, Inc. | Antibodies and methods of use thereof |
| US20200291116A1 (en) | 2020-05-18 | 2020-09-17 | Abexxa Biologics, Inc. | Antibodies and methods of use thereof |
| US20200291127A1 (en) | 2020-05-18 | 2020-09-17 | Abexxa Biologics, Inc. | Antibodies and methods of use thereof |
-
2015
- 2015-01-21 GB GBGB1501017.6A patent/GB201501017D0/en not_active Ceased
- 2015-12-16 AU AU2015371490A patent/AU2015371490B2/en not_active Ceased
- 2015-12-16 EP EP19199101.7A patent/EP3626729B1/en active Active
- 2015-12-16 MA MA40136A patent/MA40136A1/fr unknown
- 2015-12-16 EP EP19199098.5A patent/EP3616706B1/en active Active
- 2015-12-16 SI SI201531025T patent/SI3236985T2/sl unknown
- 2015-12-16 EP EP19199114.0A patent/EP3620168A1/en not_active Withdrawn
- 2015-12-16 EP EP15813809.9A patent/EP3236985B2/en active Active
- 2015-12-16 PL PL15813809.9T patent/PL3236985T5/pl unknown
- 2015-12-16 EA EA201791150A patent/EA201791150A1/ru unknown
- 2015-12-16 MA MA41237A patent/MA41237B1/fr unknown
- 2015-12-16 DK DK19199101.7T patent/DK3626729T3/da active
- 2015-12-16 PE PE2017000542A patent/PE20170940A1/es unknown
- 2015-12-16 RS RS20211276A patent/RS62448B1/sr unknown
- 2015-12-16 EP EP20172206.3A patent/EP3715357B1/en active Active
- 2015-12-16 RS RS20191606A patent/RS59836B2/sr unknown
- 2015-12-16 CN CN202011429073.4A patent/CN112646025A/zh active Pending
- 2015-12-16 CN CN201580055141.6A patent/CN107001414A/zh active Pending
- 2015-12-16 SG SG11201703322UA patent/SG11201703322UA/en unknown
- 2015-12-16 EP EP19170191.1A patent/EP3545965B1/en active Active
- 2015-12-16 RS RS20211341A patent/RS62508B1/sr unknown
- 2015-12-16 WO PCT/EP2015/080018 patent/WO2016102272A1/en not_active Ceased
- 2015-12-16 KR KR1020177017192A patent/KR102284493B1/ko active Active
- 2015-12-16 EP EP19199106.6A patent/EP3626730A1/en not_active Withdrawn
- 2015-12-16 SI SI201531682T patent/SI3545965T1/sl unknown
- 2015-12-16 CR CR20170282A patent/CR20170282A/es unknown
- 2015-12-16 BR BR112017008972-6A patent/BR112017008972A2/pt not_active Application Discontinuation
- 2015-12-16 EP EP19199125.6A patent/EP3626731B1/en active Active
- 2015-12-16 SI SI201531721T patent/SI3626729T1/sl unknown
- 2015-12-16 DK DK19199098.5T patent/DK3616706T3/da active
- 2015-12-16 DK DK19199125.6T patent/DK3626731T3/da active
- 2015-12-16 CA CA2972126A patent/CA2972126A1/en active Pending
- 2015-12-16 JP JP2017518096A patent/JP6906156B2/ja active Active
- 2015-12-16 MA MA49158A patent/MA49158B1/fr unknown
- 2015-12-16 DK DK19170191.1T patent/DK3545965T3/da active
- 2015-12-16 PH PH1/2017/500484A patent/PH12017500484B1/en unknown
- 2015-12-16 EA EA202190587A patent/EA202190587A3/ru unknown
- 2015-12-16 MX MX2017008329A patent/MX377144B/es active IP Right Grant
- 2015-12-16 CN CN202011432405.4A patent/CN112646021A/zh active Pending
- 2015-12-16 RS RS20211033A patent/RS62237B1/sr unknown
- 2015-12-16 CN CN202011429041.4A patent/CN112538109A/zh active Pending
- 2015-12-21 TW TW104142988A patent/TWI687436B/zh not_active IP Right Cessation
- 2015-12-21 US US14/975,952 patent/US10064926B2/en active Active
- 2015-12-21 AR ARP150104228A patent/AR103220A1/es not_active Application Discontinuation
-
2016
- 2016-11-21 US US15/357,757 patent/US20170080070A1/en not_active Abandoned
-
2017
- 2017-03-07 IL IL250989A patent/IL250989B/en active IP Right Grant
- 2017-05-31 CL CL2017001391A patent/CL2017001391A1/es unknown
-
2018
- 2018-03-09 US US15/917,098 patent/US20180207252A1/en not_active Abandoned
- 2018-03-12 US US15/918,788 patent/US11406693B2/en active Active
- 2018-09-18 US US16/134,422 patent/US20190000947A1/en not_active Abandoned
-
2020
- 2020-06-29 US US16/915,308 patent/US20200376103A1/en not_active Abandoned
- 2020-08-04 AU AU2020213295A patent/AU2020213295B2/en not_active Ceased
- 2020-08-04 AU AU2020213294A patent/AU2020213294B2/en not_active Ceased
- 2020-09-11 US US17/018,915 patent/US20200405831A1/en not_active Abandoned
-
2021
- 2021-03-26 JP JP2021052978A patent/JP7713309B2/ja active Active
- 2021-04-30 US US17/245,918 patent/US11786583B2/en active Active
- 2021-07-14 AR ARP210101973A patent/AR122964A2/es not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL250989A0 (en) | New peptides and a combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other types of cancer | |
| SG10202101368WA (en) | Novel peptides and combination of peptides for use in immunotherapy against various cancers | |
| IL258599A (en) | New peptides and a combination of peptides used in immunotherapy against breast cancer and other types of cancer | |
| IL256189A (en) | New peptides and combinations of peptides used in immunotherapy against ovarian cancer and other types of cancer | |
| SG11201706681VA (en) | Novel peptides and combination of peptides for use in immunotherapy against various tumors | |
| SG10202110292UA (en) | Novel peptides and combination of peptides for use in immunotherapy against nhl and other cancers | |
| GB201511792D0 (en) | Novel peptides and combination of peptides for use in immunotherapy against esopageal cancer and other cancers | |
| SG10202001665QA (en) | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers | |
| LT3394084T (lt) | Nauji peptidai ir peptidų deriniai, skirti naudoti imunoterapijai prieš krūties ir kitų tipų vėžį | |
| GB201604458D0 (en) | Peptides and combination of peptides for use in immunotherapy against cancers | |
| GB201604490D0 (en) | Peptides combination of peptides for use in immunotherapy against cancers | |
| IL258609A (en) | New peptides and a combination of peptides for use in immunotherapy against several types of cancer | |
| IL281752A (en) | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers | |
| ZA201805512B (en) | Novel peptides and combination of peptides for use in immunotherapy against nhl and other cancers |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |