MA46913B1 - Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers - Google Patents
Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancersInfo
- Publication number
- MA46913B1 MA46913B1 MA46913A MA46913A MA46913B1 MA 46913 B1 MA46913 B1 MA 46913B1 MA 46913 A MA46913 A MA 46913A MA 46913 A MA46913 A MA 46913A MA 46913 B1 MA46913 B1 MA 46913B1
- Authority
- MA
- Morocco
- Prior art keywords
- cells
- peptides
- present
- relates
- molecules
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 8
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 206010073071 hepatocellular carcinoma Diseases 0.000 title 1
- 231100000844 hepatocellular carcinoma Toxicity 0.000 title 1
- 238000009169 immunotherapy Methods 0.000 title 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 2
- 230000005975 antitumor immune response Effects 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 210000004881 tumor cell Anatomy 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 108700018351 Major Histocompatibility Complex Proteins 0.000 abstract 1
- 108091008874 T cell receptors Proteins 0.000 abstract 1
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 abstract 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 238000002619 cancer immunotherapy Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001024 immunotherapeutic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000020382 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Effects 0.000 abstract 1
Classifications
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- Analytical Chemistry (AREA)
Abstract
La présente invention concerne des peptides, des protéines, des acides nucléiques et des cellules à utiliser dans des méthodes immunothérapeutiques. En particulier, la présente invention concerne l'immunothérapie du cancer. La présente invention concerne en outre des épitopes peptidiques des cellules t associés aux tumeurs, seuls ou en combinaison avec d'autres peptides associés aux tumeurs qui peuvent par exemple servir d'ingrédients pharmaceutiques actifs de compositions vaccinales qui stimulent les réponses immunitaires anti-tumorales, ou pour stimuler les cellules t. Ex vivo et transfert aux patients. Les peptides liés aux molécules du complexe majeur d'histocompatibilité (cmh), ou les peptides en tant que tels, peuvent également être des cibles d'anticorps, de récepteurs de cellules t solubles et d'autres molécules de liaison. En particulier, la présente invention concerne plusieurs nouvelles séquences peptidiques et leurs variantes dérivées de molécules hla de classe i et de classe ii de cellules tumorales humaines qui peuvent être utilisées dans des compositions vaccinales pour déclencher des réponses immunitaires antitumorales ou comme cibles pour le développement de produits pharmaceutiques. / composés et cellules immunologiquement actifs.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201462096165P | 2014-12-23 | 2014-12-23 | |
GB201423016 | 2014-12-23 | ||
GBGB1501017.6A GB201501017D0 (en) | 2014-12-23 | 2015-01-21 | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
Publications (2)
Publication Number | Publication Date |
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MA46913A MA46913A (fr) | 2021-03-24 |
MA46913B1 true MA46913B1 (fr) | 2021-09-30 |
Family
ID=66846825
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Application Number | Title | Priority Date | Filing Date |
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MA48487A MA48487B1 (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
MA46913A MA46913B1 (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
MA050819A MA50819A (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
MA049156A MA49156A (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
MA049157A MA49157A (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
MA49155A MA49155B1 (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
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Application Number | Title | Priority Date | Filing Date |
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MA48487A MA48487B1 (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
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Application Number | Title | Priority Date | Filing Date |
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MA050819A MA50819A (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
MA049156A MA49156A (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
MA049157A MA49157A (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
MA49155A MA49155B1 (fr) | 2014-12-23 | 2015-12-16 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
Country Status (28)
Country | Link |
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US (10) | US20220016227A1 (fr) |
JP (8) | JP2020191866A (fr) |
KR (4) | KR102643923B1 (fr) |
AU (1) | AU2022268329A1 (fr) |
CL (1) | CL2021001479A1 (fr) |
CO (1) | CO2017003772A2 (fr) |
CR (1) | CR20210289A (fr) |
CY (5) | CY1122491T1 (fr) |
DK (1) | DK3236985T4 (fr) |
ES (5) | ES2887107T3 (fr) |
FI (1) | FI3236985T4 (fr) |
HR (5) | HRP20211580T1 (fr) |
HU (5) | HUE056607T2 (fr) |
IL (1) | IL281752A (fr) |
LT (5) | LT3616706T (fr) |
MA (6) | MA48487B1 (fr) |
MD (5) | MD3626731T2 (fr) |
MX (6) | MX2020004757A (fr) |
MY (1) | MY178137A (fr) |
PE (1) | PE20211740A1 (fr) |
PL (4) | PL3616706T3 (fr) |
PT (5) | PT3626729T (fr) |
RS (1) | RS62575B1 (fr) |
SG (2) | SG10202102698VA (fr) |
SI (2) | SI3626731T1 (fr) |
TW (3) | TW202321273A (fr) |
UA (1) | UA124331C2 (fr) |
ZA (1) | ZA201701762B (fr) |
Families Citing this family (2)
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CN114720691B (zh) * | 2022-05-10 | 2022-12-09 | 深圳粒影生物科技有限公司 | 一种检测生物标志物的试剂盒及其制备方法和应用 |
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MA46647A1 (fr) | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie du cancer du pancréas et d'autres cancers | |
MA43435B1 (fr) | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre diverses tumeurs (seq id 25 - mrax5-003) | |
MA43322A1 (fr) | Nouveaux peptides et combinaisons de peptides et échafaudages formés de ceux-ci destinés à être utilisés en immunothérapie contre le carcinome colorectal (crc) et d'autres cancers | |
MA43459A1 (fr) | Nouveaux peptides, combinaisons de peptides et supports pour utilisation dans le traitementimmunothérapeutique de divers cancers | |
MA46508A1 (fr) | Nouveaux épitopes de cellules et nouvelle combinaison d'épitopes de cellules destinés à être utilisés dans l'immunothérapie du myélome et d'autres cancers | |
MA42294A (fr) | Nouveaux peptides et combinaison de peptides à utiliser en immunothérapie contre le cancer de l'ovaire et d'autres cancers | |
MA46022A (fr) | Nouveaux peptides et combinaison de peptides à utiliser en immunothérapie contre le cancer de la prostate et d'autres cancers | |
MA43719B1 (fr) | Peptide à utiliser en immunothérapie contre le cancer du poumon non à petites cellules et le cancer du poumon à petites cellules | |
MA48487B1 (fr) | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers | |
MA46798B1 (fr) | Nouvelle immunothérapie contre plusieurs tumeurs, tels que le cancer du poumon, comprenant le cancer du poumon à grandes cellules |