MA46913B1 - Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers - Google Patents

Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers

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Publication number
MA46913B1
MA46913B1 MA46913A MA46913A MA46913B1 MA 46913 B1 MA46913 B1 MA 46913B1 MA 46913 A MA46913 A MA 46913A MA 46913 A MA46913 A MA 46913A MA 46913 B1 MA46913 B1 MA 46913B1
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MA
Morocco
Prior art keywords
cells
peptides
present
relates
molecules
Prior art date
Application number
MA46913A
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English (en)
Other versions
MA46913A (fr
Inventor
Andrea Mahr
Toni Weinschenk
Jens Fritsche
Phillip Müller
Anita Wiebe
Sarah Missel
Original Assignee
Immatics Biotechnologies Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Priority claimed from GBGB1501017.6A external-priority patent/GB201501017D0/en
Application filed by Immatics Biotechnologies Gmbh filed Critical Immatics Biotechnologies Gmbh
Publication of MA46913A publication Critical patent/MA46913A/fr
Publication of MA46913B1 publication Critical patent/MA46913B1/fr

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    • AHUMAN NECESSITIES
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    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K38/19Cytokines; Lymphokines; Interferons
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Abstract

La présente invention concerne des peptides, des protéines, des acides nucléiques et des cellules à utiliser dans des méthodes immunothérapeutiques. En particulier, la présente invention concerne l'immunothérapie du cancer. La présente invention concerne en outre des épitopes peptidiques des cellules t associés aux tumeurs, seuls ou en combinaison avec d'autres peptides associés aux tumeurs qui peuvent par exemple servir d'ingrédients pharmaceutiques actifs de compositions vaccinales qui stimulent les réponses immunitaires anti-tumorales, ou pour stimuler les cellules t. Ex vivo et transfert aux patients. Les peptides liés aux molécules du complexe majeur d'histocompatibilité (cmh), ou les peptides en tant que tels, peuvent également être des cibles d'anticorps, de récepteurs de cellules t solubles et d'autres molécules de liaison. En particulier, la présente invention concerne plusieurs nouvelles séquences peptidiques et leurs variantes dérivées de molécules hla de classe i et de classe ii de cellules tumorales humaines qui peuvent être utilisées dans des compositions vaccinales pour déclencher des réponses immunitaires antitumorales ou comme cibles pour le développement de produits pharmaceutiques. / composés et cellules immunologiquement actifs.
MA46913A 2014-12-23 2015-12-16 Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers MA46913B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462096165P 2014-12-23 2014-12-23
GB201423016 2014-12-23
GBGB1501017.6A GB201501017D0 (en) 2014-12-23 2015-01-21 Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers

Publications (2)

Publication Number Publication Date
MA46913A MA46913A (fr) 2021-03-24
MA46913B1 true MA46913B1 (fr) 2021-09-30

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