GB0424284D0 - Organic compounds - Google Patents

Organic compounds

Info

Publication number
GB0424284D0
GB0424284D0 GBGB0424284.8A GB0424284A GB0424284D0 GB 0424284 D0 GB0424284 D0 GB 0424284D0 GB 0424284 A GB0424284 A GB 0424284A GB 0424284 D0 GB0424284 D0 GB 0424284D0
Authority
GB
United Kingdom
Prior art keywords
organic compounds
compounds
organic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0424284.8A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33515948&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB0424284(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Priority to GBGB0424284.8A priority Critical patent/GB0424284D0/en
Publication of GB0424284D0 publication Critical patent/GB0424284D0/en
Priority to JOP/2005/0145A priority patent/JO2613B1/ar
Priority to MYPI20054966A priority patent/MY145207A/en
Priority to ARP050104547A priority patent/AR054090A1/es
Priority to ES05798470T priority patent/ES2353142T3/es
Priority to DK05798470.0T priority patent/DK1811999T3/da
Priority to MX2007005189A priority patent/MX2007005189A/es
Priority to PCT/EP2005/011662 priority patent/WO2006048225A1/en
Priority to CA2583237A priority patent/CA2583237C/en
Priority to SI200531188T priority patent/SI1811999T1/sl
Priority to PL05798470T priority patent/PL1811999T3/pl
Priority to BRPI0517945-9A priority patent/BRPI0517945A/pt
Priority to EP10156591A priority patent/EP2206499A1/en
Priority to JP2007538352A priority patent/JP4950896B2/ja
Priority to CN2005800380673A priority patent/CN101056634B/zh
Priority to AU2005300710A priority patent/AU2005300710B2/en
Priority to PT05798470T priority patent/PT1811999E/pt
Priority to DE602005023639T priority patent/DE602005023639D1/de
Priority to NZ554302A priority patent/NZ554302A/en
Priority to US11/577,417 priority patent/US7723356B2/en
Priority to HR20100693T priority patent/HRP20100693T1/hr
Priority to EP05798470A priority patent/EP1811999B1/en
Priority to RU2007120454/04A priority patent/RU2399620C2/ru
Priority to PE2005001274A priority patent/PE20060609A1/es
Priority to KR1020077009938A priority patent/KR101252307B1/ko
Priority to AT05798470T priority patent/ATE481099T1/de
Priority to TW094138292A priority patent/TW200628154A/zh
Priority to ZA200702772A priority patent/ZA200702772B/xx
Priority to IL182695A priority patent/IL182695A0/en
Priority to EC2007007424A priority patent/ECSP077424A/es
Priority to TNP2007000164A priority patent/TNSN07164A1/fr
Priority to NO20072371A priority patent/NO20072371L/no
Priority to MA29952A priority patent/MA29080B1/fr
Priority to US12/721,897 priority patent/US8084463B2/en
Priority to CY20101101081T priority patent/CY1110952T1/el
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
GBGB0424284.8A 2004-11-02 2004-11-02 Organic compounds Ceased GB0424284D0 (en)

Priority Applications (35)

Application Number Priority Date Filing Date Title
GBGB0424284.8A GB0424284D0 (en) 2004-11-02 2004-11-02 Organic compounds
JOP/2005/0145A JO2613B1 (ar) 2004-11-02 2005-10-12 مركبات عضوية
MYPI20054966A MY145207A (en) 2004-11-02 2005-10-24 Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists
KR1020077009938A KR101252307B1 (ko) 2004-11-02 2005-10-31 퀴뉴클리딘 유도체 및 그의 무스카린 ｍ３ 수용체길항제로서의 용도
AT05798470T ATE481099T1 (de) 2004-11-02 2005-10-31 Chinuclidinderivate und deren verwendung als muscarin-m3-rezeptor-antagonisten
AU2005300710A AU2005300710B2 (en) 2004-11-02 2005-10-31 Quinuclidine derivatives and their use as muscarinic M3 receptor antagonists
HR20100693T HRP20100693T1 (hr) 2004-11-02 2005-10-31 Derivati kinuklidina i njihova uporaba kao antagonista muskarinskih m3 receptora
DK05798470.0T DK1811999T3 (da) 2004-11-02 2005-10-31 Quinuclidinderivater og deres anvendelse som muskariniske M3-receptor-antagonister
MX2007005189A MX2007005189A (es) 2004-11-02 2005-10-31 Derivados de quinuclidina y su uso como antagonistas del receptor muscarinico m3.
PCT/EP2005/011662 WO2006048225A1 (en) 2004-11-02 2005-10-31 Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists
CA2583237A CA2583237C (en) 2004-11-02 2005-10-31 Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists
SI200531188T SI1811999T1 (sl) 2004-11-02 2005-10-31 Kinuklidinski derivati in njihova uporaba kot antagonisti muskarinskega M3 receptorja
PL05798470T PL1811999T3 (pl) 2004-11-02 2005-10-31 Pochodne chinuklidyny i ich zastosowanie jako antagonistów receptora muskarynowego M3
BRPI0517945-9A BRPI0517945A (pt) 2004-11-02 2005-10-31 derivados de quinuclidina e seu uso como antagonistas de receptor muscarìnico m3
EP10156591A EP2206499A1 (en) 2004-11-02 2005-10-31 Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists
JP2007538352A JP4950896B2 (ja) 2004-11-02 2005-10-31 ムスカリンｍ３受容体アンタゴニストとしてのキヌクリジン誘導体およびその使用
CN2005800380673A CN101056634B (zh) 2004-11-02 2005-10-31 奎宁环衍生物及它们作为毒蕈碱m3受体拮抗剂的用途
ARP050104547A AR054090A1 (es) 2004-11-02 2005-10-31 Derivados de quinuclidina como antagonistas del receptor muscarinico m3. composiciones farmaceuticas y proceso de obtencion
PT05798470T PT1811999E (pt) 2004-11-02 2005-10-31 Derivados de quinoclidina e sua utilizaçâo como antagonistas do receptor muscarínico m3
DE602005023639T DE602005023639D1 (de) 2004-11-02 2005-10-31 Chinuclidinderivate und deren verwendung als muscarin-m3-rezeptor-antagonisten
NZ554302A NZ554302A (en) 2004-11-02 2005-10-31 Quinuclidine derivatives and their use as muscarinic M3 receptor antagonists
US11/577,417 US7723356B2 (en) 2004-11-02 2005-10-31 Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists
ES05798470T ES2353142T3 (es) 2004-11-02 2005-10-31 Derivados de quinuclidina y su uso como antagonistas del recptor del m3 muscarínico.
EP05798470A EP1811999B1 (en) 2004-11-02 2005-10-31 Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists
RU2007120454/04A RU2399620C2 (ru) 2004-11-02 2005-10-31 Производные хинуклидина и их применение в качестве антагонистов мускариновых рецепторов м3
PE2005001274A PE20060609A1 (es) 2004-11-02 2005-10-31 Derivados de quinuclidinas como antagonistas del receptor muscarinico (m3)
TW094138292A TW200628154A (en) 2004-11-02 2005-11-01 Organic compounds
ZA200702772A ZA200702772B (en) 2004-11-02 2007-04-03 Quinuclidine derivatives and their use as muscarinic M3 receptor antagonists
IL182695A IL182695A0 (en) 2004-11-02 2007-04-19 Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists
EC2007007424A ECSP077424A (es) 2004-11-02 2007-04-27 Derivados de quinuclidina y su uso como antagonistas del receptor muscarínico m3
TNP2007000164A TNSN07164A1 (en) 2004-11-02 2007-04-30 Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists
NO20072371A NO20072371L (no) 2004-11-02 2007-05-08 Kinuklidinderivater og deres anvendelse som muskarine M3-reseptorantagonister
MA29952A MA29080B1 (fr) 2004-11-02 2007-05-30 Derives de la quinuclidine et leur utilisation en tant qu'antagonistes du recepteur m3 muscarinique
US12/721,897 US8084463B2 (en) 2004-11-02 2010-03-11 Quinuclidine derivatives and their use as muscarinic M3 receptor antagonists
CY20101101081T CY1110952T1 (el) 2004-11-02 2010-11-25 Παραγωγα κινουκλιδινης και η χρηση αυτων ως μουσκαρινικοι ανταγωνιστες υποδοχεων μ3

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0424284.8A GB0424284D0 (en) 2004-11-02 2004-11-02 Organic compounds

Publications (1)

Publication Number Publication Date
GB0424284D0 true GB0424284D0 (en) 2004-12-01

Family

ID=33515948

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0424284.8A Ceased GB0424284D0 (en) 2004-11-02 2004-11-02 Organic compounds

Country Status (33)

Country Link
US (2) US7723356B2 (https=)
EP (2) EP1811999B1 (https=)
JP (1) JP4950896B2 (https=)
KR (1) KR101252307B1 (https=)
CN (1) CN101056634B (https=)
AR (1) AR054090A1 (https=)
AT (1) ATE481099T1 (https=)
AU (1) AU2005300710B2 (https=)
BR (1) BRPI0517945A (https=)
CA (1) CA2583237C (https=)
CY (1) CY1110952T1 (https=)
DE (1) DE602005023639D1 (https=)
DK (1) DK1811999T3 (https=)
EC (1) ECSP077424A (https=)
ES (1) ES2353142T3 (https=)
GB (1) GB0424284D0 (https=)
HR (1) HRP20100693T1 (https=)
IL (1) IL182695A0 (https=)
JO (1) JO2613B1 (https=)
MA (1) MA29080B1 (https=)
MX (1) MX2007005189A (https=)
MY (1) MY145207A (https=)
NO (1) NO20072371L (https=)
NZ (1) NZ554302A (https=)
PE (1) PE20060609A1 (https=)
PL (1) PL1811999T3 (https=)
PT (1) PT1811999E (https=)
RU (1) RU2399620C2 (https=)
SI (1) SI1811999T1 (https=)
TN (1) TNSN07164A1 (https=)
TW (1) TW200628154A (https=)
WO (1) WO2006048225A1 (https=)
ZA (1) ZA200702772B (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR044134A1 (es) 2003-05-02 2005-08-24 Novartis Ag Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas.
JP2009504624A (ja) 2005-08-08 2009-02-05 アージェンタ ディスカバリー リミテッド ビシクロ［２．２．１］ヘプタ−７−イルアミン誘導体およびその使用
EP1940775A2 (en) 2005-08-11 2008-07-09 University of Massachusetts Methods and compositions for the efficient delivery of therapeutic agents to cells and animals
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
EP1894568A1 (en) * 2006-08-31 2008-03-05 Novartis AG Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases
TW200825084A (en) * 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
ATE555111T1 (de) * 2006-12-19 2012-05-15 Astrazeneca Ab Chinuclidinol-derivate als muscarinrezeptor- antagonisten
JP5656288B2 (ja) 2007-09-07 2015-01-21 セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー ムスカリン受容体アンタゴニストとして有用なグアジニン含有化合物
US8017617B2 (en) 2007-12-14 2011-09-13 Theravance, Inc. Amidine-containing compounds useful as muscarinic receptor antagonists
AU2009203693B2 (en) 2008-01-11 2012-06-07 Novartis Ag Pyrimidines as kinase inhibitors
GB0808707D0 (en) * 2008-05-13 2008-06-18 Argenta Discovery Ltd New compounds 275
BRPI0912657A2 (pt) * 2008-05-13 2016-01-26 Astrazeneca Ab produto farmacêutico compreendendo um antagonista de receptor muscarínico e um agonista beta2-adrenorreceptor
EA017627B1 (ru) * 2008-05-13 2013-01-30 Астразенека Аб Хинуклидиновые производные в качестве антагонистов мускаринового м3 рецептора
GB0808708D0 (en) * 2008-05-13 2008-06-18 Astrazeneca Ab New compounds 274
US20090326004A1 (en) * 2008-06-03 2009-12-31 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
WO2009153536A1 (en) * 2008-06-17 2009-12-23 Argenta Discovery Limited 1-aza-bicyclo [2.2.2] octane derivatives useful as muscarinic receptor antagonists
GB0811100D0 (en) * 2008-06-17 2008-07-23 Astrazeneca Ab New combination
US8263623B2 (en) 2008-07-11 2012-09-11 Pfizer Inc. Triazol derivatives useful for the treatment of diseases
EP2206712A1 (en) * 2008-12-23 2010-07-14 CHIESI FARMACEUTICI S.p.A. "Alkaloid aminoester derivatives and medicinal composition thereof"
ES2617680T3 (es) 2009-04-09 2017-06-19 Novartis Ag Proceso para la preparación de sales de pirrolidinio
EP2585457B1 (en) * 2010-06-22 2015-07-22 Chiesi Farmaceutici S.p.A. Alkaloid aminoester derivatives and medicinal composition thereof
JP2013529606A (ja) * 2010-06-22 2013-07-22 シエシー ファルマセウティチィ ソシエタ ペル アチオニ 抗ムスカリン薬含有乾燥粉末配合物
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
MA34969B1 (fr) 2011-02-25 2014-03-01 Irm Llc Composes et compositions en tant qu inibiteurs de trk
JP2011195593A (ja) * 2011-06-30 2011-10-06 Astrazeneca Ab ムスカリンｍ３受容体アンタゴニストとしてのキヌクリジン誘導体
US9630945B2 (en) 2012-12-19 2017-04-25 Novartis Ag Autotaxin inhibitors
EP3134398A1 (en) 2014-04-24 2017-03-01 Novartis Ag Autotaxin inhibitors
EP3139924A4 (en) * 2014-05-06 2018-03-07 Anthony G. Visco Methods of treating or preventing preterm labor
CN109851615B (zh) * 2019-04-22 2021-06-08 上海旭东海普药业有限公司 纯化戊乙奎醚的方法

Family Cites Families (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833592A (en) 1966-05-31 1974-09-03 Little Inc A Tropanyl alpha,alpha-diphenyl-alpha-fluoroacetate esters
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
JPS6235216A (ja) 1985-08-09 1987-02-16 Noritoshi Nakabachi 不均質物質層の層厚非破壊測定方法および装置
GB8916480D0 (en) 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
PT100441A (pt) 1991-05-02 1993-09-30 Smithkline Beecham Corp Pirrolidinonas, seu processo de preparacao, composicoes farmaceuticas que as contem e uso
GB9119705D0 (en) * 1991-09-14 1991-10-30 Pfizer Ltd Therapeutic compounds
WO1993018007A1 (fr) 1992-03-13 1993-09-16 Tokyo Tanabe Company Limited Nouveau derive de carbostyrile
JP3192424B2 (ja) 1992-04-02 2001-07-30 スミスクライン・ビーチャム・コーポレイション アレルギーまたは炎症疾患の治療用化合物
US5552438A (en) 1992-04-02 1996-09-03 Smithkline Beecham Corporation Compounds useful for treating allergic and inflammatory diseases
JP3251587B2 (ja) 1992-04-02 2002-01-28 スミスクライン・ビーチャム・コーポレイション 炎症疾患の治療および腫瘍壊死因子の産生阻害に有用な化合物
GB9301000D0 (en) 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
GB9414193D0 (en) 1994-07-14 1994-08-31 Glaxo Group Ltd Compounds
GB9414208D0 (en) 1994-07-14 1994-08-31 Glaxo Group Ltd Compounds
GB9617730D0 (en) 1996-08-23 1996-10-02 Pfizer Ltd Quarternary ammonium compounds
GB9622386D0 (en) 1996-10-28 1997-01-08 Sandoz Ltd Organic compounds
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
WO1999016766A1 (en) 1997-10-01 1999-04-08 Kyowa Hakko Kogyo Co., Ltd. Benzodioxole derivatives
GB9723590D0 (en) 1997-11-08 1998-01-07 Glaxo Group Ltd Chemical compounds
GB9723589D0 (en) 1997-11-08 1998-01-07 Glaxo Group Ltd Chemical compounds
GB9723566D0 (en) 1997-11-08 1998-01-07 Glaxo Group Ltd Chemical compounds
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
AR017457A1 (es) 1998-02-14 2001-09-05 Glaxo Group Ltd Compuestos derivados de 2-(purin-9-il)-tetrahidrofuran-3,4-diol, procesos para su preparacion, composiciones que los contienen y su uso en terapia para el tratamiento de enfermedades inflamatorias.
US6541669B1 (en) 1998-06-08 2003-04-01 Theravance, Inc. β2-adrenergic receptor agonists
GB9813535D0 (en) 1998-06-23 1998-08-19 Glaxo Group Ltd Chemical compounds
JP3933870B2 (ja) 1998-06-23 2007-06-20 グラクソ グループ リミテッド ２−（プリン−９−イル）−テトラヒドロフラン−３，４−ジオール誘導体
GB9813540D0 (en) 1998-06-23 1998-08-19 Glaxo Group Ltd Chemical compounds
GB9813565D0 (en) 1998-06-23 1998-08-19 Glaxo Group Ltd Chemical compounds
BR9815931A (pt) 1998-06-30 2001-02-20 Dow Chemical Co Polióis poliméricos, um processo para sua produção, e espuma de poliuretanoobtida
DE69932173T2 (de) 1998-10-16 2007-06-06 Pfizer Inc. Adeninderivate
GB9913083D0 (en) 1999-06-04 1999-08-04 Novartis Ag Organic compounds
YU25500A (sh) 1999-05-11 2003-08-29 Pfizer Products Inc. Postupak za sintezu analoga nukleozida
US6683115B2 (en) 1999-06-02 2004-01-27 Theravance, Inc. β2-adrenergic receptor agonists
GB9913932D0 (en) 1999-06-15 1999-08-18 Pfizer Ltd Purine derivatives
US6322771B1 (en) 1999-06-18 2001-11-27 University Of Virginia Patent Foundation Induction of pharmacological stress with adenosine receptor agonists
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
CA2715683A1 (en) 1999-08-21 2001-03-01 Nycomed Gmbh Synergistic combination
CO5180581A1 (es) 1999-09-30 2002-07-30 Pfizer Prod Inc Compuestos para el tratamiento de la isquemia ciones farmaceuticas que los contienen para el tratamiento de la isquemia
GB9924361D0 (en) 1999-10-14 1999-12-15 Pfizer Ltd Purine derivatives
GB9924363D0 (en) 1999-10-14 1999-12-15 Pfizer Central Res Purine derivatives
OA11558A (en) 1999-12-08 2004-06-03 Advanced Medicine Inc Beta 2-adrenergic receptor agonists.
GB0003960D0 (en) 2000-02-18 2000-04-12 Pfizer Ltd Purine derivatives
SK15382002A3 (sk) 2000-04-27 2003-03-04 Boehringer Ingelheim Pharma Kg Betamimetiká, farmaceutický prostriedok s ich obsahom a ich použitie
TWI227240B (en) 2000-06-06 2005-02-01 Pfizer 2-aminocarbonyl-9H-purine derivatives
KR100751981B1 (ko) * 2000-06-27 2007-08-28 라보라토리오스 살바트, 에스.에이. 아릴알킬아민으로부터 유도된 카바메이트
GB0015727D0 (en) 2000-06-27 2000-08-16 Pfizer Ltd Purine derivatives
GB0015876D0 (en) 2000-06-28 2000-08-23 Novartis Ag Organic compounds
DE10038639A1 (de) 2000-07-28 2002-02-21 Schering Ag Nichtsteroidale Entzündungshemmer
SI1775305T1 (sl) 2000-08-05 2015-01-30 Glaxo Group Limited S-fluorometil ester 6alfa,9alfa-difluoro-17alfa-((2-furanilkarboksil)oksi)- 11beta-hidroksi-16alfa-metil-3-okso-androst-1,4-dien-17-karbotiojske kisline kot protivnetno sredstvo
US6479510B2 (en) 2000-08-18 2002-11-12 Pharmacia & Upjohn Company Quinuclidine-substituted aryl compounds for treatment of disease
WO2002016357A2 (en) 2000-08-18 2002-02-28 Pharmacia & Upjohn Company Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
AU2001284645A1 (en) 2000-08-18 2002-03-04 Pharmacia And Upjohn Company Quinuclidine-substituted aryl compounds for treatment of disease
AU2001282875A1 (en) 2000-08-21 2002-03-04 Pharmacia And Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease
US6599916B2 (en) 2000-08-21 2003-07-29 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease
WO2002016355A2 (en) 2000-08-21 2002-02-28 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic) acetylcholine receptor ligands
GB0022695D0 (en) 2000-09-15 2000-11-01 Pfizer Ltd Purine Derivatives
GB0028383D0 (en) 2000-11-21 2001-01-03 Novartis Ag Organic compounds
NZ526580A (en) 2000-12-22 2005-04-29 Almirall Prodesfarma Ag Quinuclidine carbamate derivatives and their use as M3 antagonists
US6476222B2 (en) 2001-01-05 2002-11-05 Sun Chemical Corporation Preparation of heat stable pigment violet 23
GB0103630D0 (en) 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
US7144908B2 (en) 2001-03-08 2006-12-05 Glaxo Group Limited Agonists of beta-adrenoceptors
EP1241176A1 (en) 2001-03-16 2002-09-18 Pfizer Products Inc. Purine derivatives for the treatment of ischemia
ES2296923T3 (es) 2001-03-22 2008-05-01 Glaxo Group Limited Derivados formanilidas como agonistas del adrenorreceptor beta2.
KR100831534B1 (ko) 2001-04-30 2008-05-22 글락소 그룹 리미티드 17.알파 위치에 시클릭 에스테르기를 지닌 항염증성의안드로스탄의 17.베타.-카르보티오에이트 에스테르 유도체
WO2002096462A1 (en) 2001-05-25 2002-12-05 Pfizer Inc. An adenosine a2a receptor agonist and an anticholinergic agent in combination for treating obstructive airways diseases
ES2307751T3 (es) 2001-06-12 2008-12-01 Glaxo Group Limited Nuevos esteres heterociclicos centi-inflamatorios 17 alfa de derivados 17 beta de carbotioato de androstano.
KR20090057477A (ko) 2001-09-14 2009-06-05 글락소 그룹 리미티드 호흡기 질환 치료용 펜에탄올아민 유도체
GB0125259D0 (en) 2001-10-20 2001-12-12 Glaxo Group Ltd Novel compounds
AR037517A1 (es) 2001-11-05 2004-11-17 Novartis Ag Derivados de naftiridinas, un proceso para su preparacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento para el tratamiento de una enfermedad inflamatoria
US6653323B2 (en) 2001-11-13 2003-11-25 Theravance, Inc. Aryl aniline β2 adrenergic receptor agonists
TWI249515B (en) 2001-11-13 2006-02-21 Theravance Inc Aryl aniline beta2 adrenergic receptor agonists
AU2002356759A1 (en) 2001-12-01 2003-06-17 Glaxo Group Limited 17.alpha. -cyclic esters of 16-methylpregnan-3,20-dione as anti-inflammatory agents
JP4505227B2 (ja) 2001-12-20 2010-07-21 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ １−アルキル−１−アゾニアビシクロ［２．２．２］オクタンカルバメート誘導体およびムスカリンレセプターアンタゴニストとしてのそれらの使用
AU2003202044A1 (en) 2002-01-15 2003-09-09 Glaxo Group Limited 17.alpha-cycloalkyl/cycloylkenyl esters of alkyl-or haloalkyl-androst-4-en-3-on-11.beta.,17.alpha.-diol 17.beta.-carboxylates as anti-inflammatory agents
AU2003201693A1 (en) 2002-01-21 2003-09-02 Glaxo Group Limited Non-aromatic 17.alpha.-esters of androstane-17.beta.-carboxylate esters as anti-inflammatory agents
GB0202216D0 (en) 2002-01-31 2002-03-20 Glaxo Group Ltd Novel compounds
GB0204719D0 (en) 2002-02-28 2002-04-17 Glaxo Group Ltd Medicinal compounds
CA2478156C (en) 2002-03-26 2011-02-15 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
WO2003082787A1 (en) 2002-03-26 2003-10-09 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
EP1496911B1 (en) 2002-04-10 2007-12-19 University Of Virginia Patent Foundation Use of a combination comprising a2a adenosine receptor agonists and anti-pathogenic agents for the treatment of inflammatory diseases
EP1496892B1 (en) 2002-04-11 2011-01-26 Merck Sharp & Dohme Corp. 1h-benzo(f)indazol-5-yl derivatives as selective glucocorticoid receptor modulators
JP2005523920A (ja) 2002-04-25 2005-08-11 グラクソ　グループ　リミテッド フェネタノールアミン誘導体
WO2003099764A1 (en) 2002-05-28 2003-12-04 Theravance, Inc. ALKOXY ARYL β2 ADRENERGIC RECEPTOR AGONISTS
US7186864B2 (en) 2002-05-29 2007-03-06 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
DE10224888A1 (de) 2002-06-05 2003-12-24 Merck Patent Gmbh Pyridazinderivate
US7074806B2 (en) 2002-06-06 2006-07-11 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
DE10225574A1 (de) 2002-06-10 2003-12-18 Merck Patent Gmbh Aryloxime
DE10227269A1 (de) 2002-06-19 2004-01-08 Merck Patent Gmbh Thiazolderivate
ES2203327B1 (es) 2002-06-21 2005-06-16 Almirall Prodesfarma, S.A. Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen.
ATE356808T1 (de) 2002-06-25 2007-04-15 Merck Frosst Canada Ltd 8-(biaryl)chinolin-pde4-inhibitoren
AU2003281219A1 (en) 2002-07-02 2004-01-23 Bernard Cote Di-aryl-substituted-ethane pyridone pde4 inhibitors
JP4503436B2 (ja) 2002-07-08 2010-07-14 ファイザー・プロダクツ・インク 糖質コルチコイド受容体のモジュレーター
GB0217225D0 (en) 2002-07-25 2002-09-04 Glaxo Group Ltd Medicinal compounds
PE20050130A1 (es) 2002-08-09 2005-03-29 Novartis Ag Compuestos organicos
BR0313330A (pt) 2002-08-10 2005-06-14 Altana Pharma Ag Piperidina-ftalazonas substituìdas com pirrolidinadiona como inibidores de pde4
EP1556369A1 (en) 2002-08-10 2005-07-27 ALTANA Pharma AG Pyridazinone-derivatives as pde4 inhibitors
WO2004018449A1 (en) 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
US20060166995A1 (en) 2002-08-10 2006-07-27 Altana Pharma Ag Piperidine-n-oxide-derivatives
RS20050117A (sr) 2002-08-17 2007-06-04 Altana Pharma Ag., Novi benzonaftiridini
CA2495597A1 (en) 2002-08-17 2004-03-04 Altana Pharma Ag Novel phenanthridines
JP2006504678A (ja) 2002-08-21 2006-02-09 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド グルココルチコイドミメチックス、その製造方法、その医薬組成物、及び使用
ATE353217T1 (de) 2002-08-29 2007-02-15 Altana Pharma Ag 3-hydroxy-6-phenylphenanthridine als pde-4 inhibitoren
WO2004019935A1 (en) 2002-08-29 2004-03-11 Boehringer Ingelheim Pharmaceuticals, Inc. -3 (sulfonamidoethyl) -indole derivaties for use as glucocorticoid mimetics in the treatment of inflammatory, allergic and proliferative diseases
JP4587294B2 (ja) 2002-08-29 2010-11-24 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｐｄｅ４インヒビターとしての２−ヒドロキシ−６−フェニルフェナントリジン
GB0220730D0 (en) 2002-09-06 2002-10-16 Glaxo Group Ltd Medicinal compounds
AU2003270783C1 (en) 2002-09-20 2010-05-20 Merck Sharp & Dohme Corp. Octahydro-2-H-naphtho[1,2-F] indole-4-carboxamide derivatives as selective glucocorticoid receptor modulators
DE10246374A1 (de) 2002-10-04 2004-04-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Betamimetika mit verlängerter Wirkungsdauer, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
EP1440966A1 (en) 2003-01-10 2004-07-28 Pfizer Limited Indole derivatives useful for the treatment of diseases
ES2302938T3 (es) 2002-10-11 2008-08-01 Pfizer Inc. Derivados de indol como agonistas beta-2.
EP1554264B1 (en) 2002-10-22 2007-08-08 Glaxo Group Limited Medicinal arylethanolamine compounds
EA010408B1 (ru) 2002-10-23 2008-08-29 Гленмарк Фармасьютикалс Лтд. Трициклические соединения для лечения воспалительных и аллергических нарушений, способы их приготовления и содержащие их фармацевтические составы
EP1556342B1 (en) 2002-10-28 2008-03-26 Glaxo Group Limited Phenethanolamine derivative for the treatment of respiratory diseases
GB0225030D0 (en) 2002-10-28 2002-12-04 Glaxo Group Ltd Medicinal compounds
GB0225287D0 (en) 2002-10-30 2002-12-11 Glaxo Group Ltd Novel compounds
GB0225535D0 (en) 2002-11-01 2002-12-11 Glaxo Group Ltd Medicinal compounds
GB0225540D0 (en) 2002-11-01 2002-12-11 Glaxo Group Ltd Medicinal compounds
DE10253282A1 (de) 2002-11-15 2004-05-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
DE10253426B4 (de) 2002-11-15 2005-09-22 Elbion Ag Neue Hydroxyindole, deren Verwendung als Inhibitoren der Phosphodiesterase 4 und Verfahren zu deren Herstellung
DE10253220A1 (de) 2002-11-15 2004-05-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Dihydroxy-Methyl-Phenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE10261874A1 (de) 2002-12-20 2004-07-08 Schering Ag Nichtsteroidale Entzündungshemmer
CA2512987C (en) 2003-01-21 2011-06-14 Merck & Co., Inc. 17-carbamoyloxy cortisol derivatives as selective glucocorticoid receptor modulators
EP1460064A1 (en) 2003-03-14 2004-09-22 Pfizer Limited Indole-2-carboxamide derivatives useful as beta-2 agonists
JP4767842B2 (ja) 2003-04-01 2011-09-07 セラヴァンス， インコーポレーテッド β２アドレナリン作用性レセプターアゴニスト活性およびムスカリン性レセプターアンタゴニスト活性を有するジアリールメチル化合物および関連化合物
BRPI0409198A (pt) 2003-04-04 2006-05-02 Novartis Ag derivados quinolin-2-ona para o tratamento de doenças de vias aéreas
AR044134A1 (es) * 2003-05-02 2005-08-24 Novartis Ag Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas.
EP1477167A1 (en) 2003-05-15 2004-11-17 Pfizer Limited [(2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)-ethylamino)-propyl] phenyl derivatives as beta2 agonists
US7268147B2 (en) 2003-05-15 2007-09-11 Pfizer Inc Compounds useful for the treatment of diseases
DE602004021921D1 (de) 2003-05-28 2009-08-20 Theravance Inc Azabicycloalkanverbindungen als muscarinrezeptor antagonisten
GB0312832D0 (en) 2003-06-04 2003-07-09 Pfizer Ltd 2-amino-pyridine derivatives useful for the treatment of diseases
EP1633714B1 (en) 2003-06-04 2008-01-23 Pfizer Limited 2-amino-pyridine derivatives as beta-2 adrenoreceptor agonists
DE10332239B3 (de) 2003-07-16 2005-03-03 Framatome Anp Gmbh Zirkoniumlegierung und Bauteile für den Kern von leichtwassergekühlten Kernreaktoren
WO2005033121A2 (en) 2003-10-03 2005-04-14 King Pharmaceuticals Research & Development, Inc. Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs
GB0323701D0 (en) 2003-10-09 2003-11-12 Glaxo Group Ltd Formulations
GB0324654D0 (en) 2003-10-22 2003-11-26 Glaxo Group Ltd Medicinal compounds
GB0324886D0 (en) 2003-10-24 2003-11-26 Glaxo Group Ltd Medicinal compounds
GB0329182D0 (en) 2003-12-17 2004-01-21 Glaxo Group Ltd Chemical compounds
US7591941B2 (en) 2003-12-19 2009-09-22 Shell Oil Company Systems, methods, and catalysts for producing a crude product
DE102004001413A1 (de) 2004-01-09 2005-08-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg 3-Hydroxymethyl-4-Hydroxy-Phenyl-Derivate zur Behandlung von chronisch obstruktiver Lungenerkrankung
TW200531692A (en) 2004-01-12 2005-10-01 Theravance Inc Aryl aniline derivatives as β2 adrenergic receptor agonists
ES2239546B1 (es) * 2004-03-15 2006-12-01 Almirall Prodesfarma, S.A. Nuevos esteres de quinuclidina cuaternizados.
UY28871A1 (es) 2004-04-27 2005-11-30 Glaxo Group Ltd Antagonistas del receptor de acetilcolina muscarinico
ES2246170B1 (es) 2004-07-29 2007-04-01 Almirall Prodesfarma, S.A. Nuevo procedimiento para preparar derivados de carbamato de quinuclidinio.

Also Published As

Publication number Publication date
AU2005300710B2 (en) 2009-05-14
US20100168132A1 (en) 2010-07-01
KR20070073849A (ko) 2007-07-10
AR054090A1 (es) 2007-06-06
EP1811999A1 (en) 2007-08-01
JO2613B1 (ar) 2011-11-01
NZ554302A (en) 2009-12-24
DK1811999T3 (da) 2010-12-13
PL1811999T3 (pl) 2011-03-31
EP2206499A1 (en) 2010-07-14
TW200628154A (en) 2006-08-16
US20090048281A1 (en) 2009-02-19
IL182695A0 (en) 2007-09-20
ECSP077424A (es) 2007-05-30
US7723356B2 (en) 2010-05-25
JP2008518890A (ja) 2008-06-05
CN101056634B (zh) 2011-11-30
NO20072371L (no) 2007-07-12
CN101056634A (zh) 2007-10-17
US8084463B2 (en) 2011-12-27
TNSN07164A1 (en) 2008-11-21
RU2399620C2 (ru) 2010-09-20
MX2007005189A (es) 2007-05-11
PE20060609A1 (es) 2006-08-21
ES2353142T3 (es) 2011-02-25
MY145207A (en) 2012-01-13
KR101252307B1 (ko) 2013-04-08
RU2007120454A (ru) 2008-12-10
CA2583237A1 (en) 2006-05-11
AU2005300710A1 (en) 2006-05-11
CY1110952T1 (el) 2015-06-11
PT1811999E (pt) 2010-10-29
BRPI0517945A (pt) 2008-10-21
SI1811999T1 (sl) 2011-01-31
EP1811999B1 (en) 2010-09-15
HRP20100693T1 (hr) 2011-01-31
MA29080B1 (fr) 2007-12-03
JP4950896B2 (ja) 2012-06-13
CA2583237C (en) 2013-01-22
ATE481099T1 (de) 2010-10-15
DE602005023639D1 (de) 2010-10-28
WO2006048225A1 (en) 2006-05-11
ZA200702772B (en) 2008-08-27

Similar Documents

Publication Publication Date Title
GB0410712D0 (en) Organic compounds
GB0409921D0 (en) Organic compounds
GB0403038D0 (en) Organic compounds
GB0407723D0 (en) Organic compounds
GB0424284D0 (en) Organic compounds
GB0404434D0 (en) Organic compounds
GB0401334D0 (en) Organic compounds
GB0405289D0 (en) Organic compounds
GB0402797D0 (en) Organic compounds
GB0408078D0 (en) Organic compounds
GB0400781D0 (en) Organic compounds
GB0403115D0 (en) Organic compounds
GB0406515D0 (en) Organic compounds
GB0403254D0 (en) Organic compounds
GB0409236D0 (en) Organic compounds
GB0405723D0 (en) Organic compounds
GB0406240D0 (en) Organic compounds
GB0405034D0 (en) Organic compounds
GB0407607D0 (en) Organic compounds
GB0407468D0 (en) Organic compounds
GB0405898D0 (en) Organic compounds
GB0410264D0 (en) Organic compounds
GB0400179D0 (en) Organic compounds
GB0403964D0 (en) Organic compounds
GB0410261D0 (en) Organic compounds

Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)