GB0112834D0 - Medicaments - Google Patents

Medicaments

Info

Publication number
GB0112834D0
GB0112834D0 GBGB0112834.7A GB0112834A GB0112834D0 GB 0112834 D0 GB0112834 D0 GB 0112834D0 GB 0112834 A GB0112834 A GB 0112834A GB 0112834 D0 GB0112834 D0 GB 0112834D0
Authority
GB
United Kingdom
Prior art keywords
medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0112834.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Priority to GBGB0112834.7A priority Critical patent/GB0112834D0/en
Publication of GB0112834D0 publication Critical patent/GB0112834D0/en
Priority to TW091110839A priority patent/TWI232219B/zh
Priority to ARP020101914A priority patent/AR038172A1/es
Priority to AT02807202T priority patent/ATE380812T1/de
Priority to PCT/EP2002/005708 priority patent/WO2003087098A1/en
Priority to ES02807202T priority patent/ES2298439T3/es
Priority to PL02367079A priority patent/PL367079A1/xx
Priority to CA002448525A priority patent/CA2448525A1/en
Priority to JP2003584054A priority patent/JP4463565B2/ja
Priority to KR10-2003-7015379A priority patent/KR20040010654A/ko
Priority to CNA028146689A priority patent/CN1535272A/zh
Priority to IL15886902A priority patent/IL158869A0/xx
Priority to EP02807202A priority patent/EP1399443B1/en
Priority to US10/478,154 priority patent/US7141564B2/en
Priority to HU0400017A priority patent/HUP0400017A2/hu
Priority to AU2002367697A priority patent/AU2002367697A1/en
Priority to CZ20033202A priority patent/CZ20033202A3/cs
Priority to DE60224039T priority patent/DE60224039T2/de
Priority to BR0210016-9A priority patent/BR0210016A/pt
Priority to MXPA03010790A priority patent/MXPA03010790A/es
Priority to ZA200308696A priority patent/ZA200308696B/en
Priority to CO03101671A priority patent/CO5540344A2/es
Priority to NO20035190A priority patent/NO20035190D0/no
Priority to US11/604,045 priority patent/US20070135422A1/en
Priority to JP2009259981A priority patent/JP2010031057A/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GBGB0112834.7A 2001-05-25 2001-05-25 Medicaments Ceased GB0112834D0 (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
GBGB0112834.7A GB0112834D0 (en) 2001-05-25 2001-05-25 Medicaments
TW091110839A TWI232219B (en) 2001-05-25 2002-05-23 Compounds containing cyclohexane group, process for preparing them and pharmaceutical composition containing them
ARP020101914A AR038172A1 (es) 2001-05-25 2002-05-23 Compuesto de ciclohexano y ciclohexeno, su uso para preparar una composicion farmaceutica, dicha composicion farmaceutica, procedimiento para preparar el compuesto y compuestos intermediarios en dicho procedimiento
MXPA03010790A MXPA03010790A (es) 2001-05-25 2002-05-24 Heterociclos biciclicos que contienen nitrogeno para uso como antibacterianos.
EP02807202A EP1399443B1 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
HU0400017A HUP0400017A2 (hu) 2001-05-25 2002-05-24 Antibakteriális hatóanyakokként alkalmazható nitrogéntartalmú biciklusos heterociklusos vegyületek, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
ES02807202T ES2298439T3 (es) 2001-05-25 2002-05-24 Heterociclos biciclicos que contienen nitrogeno para uso como agentes antibacterianos.
PL02367079A PL367079A1 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
CA002448525A CA2448525A1 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
JP2003584054A JP4463565B2 (ja) 2001-05-25 2002-05-24 抗菌剤として用いるための窒素含有二環式複素環
KR10-2003-7015379A KR20040010654A (ko) 2001-05-25 2002-05-24 항균제용 질소-함유 비시클릭 헤테로고리 화합물
CNA028146689A CN1535272A (zh) 2001-05-25 2002-05-24 用于抗菌剂的二环含氮杂环
IL15886902A IL158869A0 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
AT02807202T ATE380812T1 (de) 2001-05-25 2002-05-24 Stickstoffhaltige, bicyclische heterocyclen zur verwendung als antibakterielle mittel
US10/478,154 US7141564B2 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
PCT/EP2002/005708 WO2003087098A1 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
AU2002367697A AU2002367697A1 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
CZ20033202A CZ20033202A3 (cs) 2001-05-25 2002-05-24 Bicyklické heterocyklické sloučeniny obsahující dusík pro použití jako antibakteriální činidla
DE60224039T DE60224039T2 (de) 2001-05-25 2002-05-24 Stickstoffhaltige, bicyclische heterocyclen zur verwendung als antibakterielle mittel
BR0210016-9A BR0210016A (pt) 2001-05-25 2002-05-24 Heterociclos bicìclicos contendo nitrogênio, para uso como antibacterianos
ZA200308696A ZA200308696B (en) 2001-05-25 2003-11-07 Nitrogen-containing bicyclic heterocycles for use as antibacterials.
CO03101671A CO5540344A2 (es) 2001-05-25 2003-11-18 Medicamentos
NO20035190A NO20035190D0 (no) 2001-05-25 2003-11-21 Nitrogenholdige bisykliske heterosykler for anvendelse som antibakteriellemidler
US11/604,045 US20070135422A1 (en) 2001-05-25 2006-11-22 Nitrogen-containing bicycle heterocycles for use as antibacterials
JP2009259981A JP2010031057A (ja) 2001-05-25 2009-11-13 抗菌剤として用いるための窒素含有二環式複素環

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0112834.7A GB0112834D0 (en) 2001-05-25 2001-05-25 Medicaments

Publications (1)

Publication Number Publication Date
GB0112834D0 true GB0112834D0 (en) 2001-07-18

Family

ID=9915342

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0112834.7A Ceased GB0112834D0 (en) 2001-05-25 2001-05-25 Medicaments

Country Status (23)

Country Link
US (2) US7141564B2 (cg-RX-API-DMAC7.html)
EP (1) EP1399443B1 (cg-RX-API-DMAC7.html)
JP (2) JP4463565B2 (cg-RX-API-DMAC7.html)
KR (1) KR20040010654A (cg-RX-API-DMAC7.html)
CN (1) CN1535272A (cg-RX-API-DMAC7.html)
AR (1) AR038172A1 (cg-RX-API-DMAC7.html)
AT (1) ATE380812T1 (cg-RX-API-DMAC7.html)
AU (1) AU2002367697A1 (cg-RX-API-DMAC7.html)
BR (1) BR0210016A (cg-RX-API-DMAC7.html)
CA (1) CA2448525A1 (cg-RX-API-DMAC7.html)
CO (1) CO5540344A2 (cg-RX-API-DMAC7.html)
CZ (1) CZ20033202A3 (cg-RX-API-DMAC7.html)
DE (1) DE60224039T2 (cg-RX-API-DMAC7.html)
ES (1) ES2298439T3 (cg-RX-API-DMAC7.html)
GB (1) GB0112834D0 (cg-RX-API-DMAC7.html)
HU (1) HUP0400017A2 (cg-RX-API-DMAC7.html)
IL (1) IL158869A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA03010790A (cg-RX-API-DMAC7.html)
NO (1) NO20035190D0 (cg-RX-API-DMAC7.html)
PL (1) PL367079A1 (cg-RX-API-DMAC7.html)
TW (1) TWI232219B (cg-RX-API-DMAC7.html)
WO (1) WO2003087098A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200308696B (cg-RX-API-DMAC7.html)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9703377D0 (sv) * 1997-09-18 1997-09-18 Astra Ab New compounds
US6803369B1 (en) 2000-07-25 2004-10-12 Smithkline Beecham Corporation Compounds and methods for the treatment of neoplastic disease
CN1452619A (zh) 2000-07-26 2003-10-29 史密斯克莱·比奇曼公司 具有抗细菌活性的氨基哌啶喹啉和它们的氮杂等排的类似物
EP1320529B1 (en) * 2000-09-21 2006-05-24 Smithkline Beecham Plc Quinoline derivatives as antibacterials
GB0031088D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0031086D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112836D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) * 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
US7109213B2 (en) 2002-01-29 2006-09-19 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
US7312212B2 (en) * 2002-01-29 2007-12-25 Glaxo Group Limited Aminopiperidine derivatives
TW200406413A (en) * 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
TW200409637A (en) * 2002-06-26 2004-06-16 Glaxo Group Ltd Compounds
AU2003303956A1 (en) * 2002-11-05 2004-11-23 Smithkline Beecham Corporation Antibacterial agents
US7618959B2 (en) 2002-11-05 2009-11-17 Smithklinebeecham Corp Antibacterial agents
ES2312839T3 (es) * 2002-12-04 2009-03-01 Glaxo Group Limited Quinolinas y sus derivados nitrogenados y su uso como agentes antibacterianos.
US7589207B2 (en) 2002-12-13 2009-09-15 Smithkline Beecham Corporation Cyclohexyl compounds as CCR5 antagonists
TW200427688A (en) * 2002-12-18 2004-12-16 Glaxo Group Ltd Antibacterial agents
DE102004023635A1 (de) * 2004-05-10 2006-04-13 Grünenthal GmbH Heteroarylsubstituierte Cyclohexyl-1,4-diamin-Derivate
DE102004041163A1 (de) * 2004-08-25 2006-03-02 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
US7648980B2 (en) * 2005-01-25 2010-01-19 Glaxo Group Limited Antibacterial agents
WO2006081289A2 (en) * 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents
US7605169B2 (en) 2005-01-25 2009-10-20 Glaxo Group Limited Antibacterial agents
EP1846418A4 (en) 2005-01-25 2009-12-23 Glaxo Group Ltd ANTIBACTERIAL ACTIVE SUBSTANCES
US7709472B2 (en) 2005-01-25 2010-05-04 Glaxo Group Limited Antibacterial agents
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
CA2635126A1 (en) 2006-01-26 2007-08-02 Actelion Pharmaceuticals Ltd Tetrahydropyrane antibiotics
WO2007093963A1 (en) * 2006-02-15 2007-08-23 Actelion Pharmaceuticals Ltd Ethanol or 1,2-ethanediol cyclohexyl antibiotic derivatives
JP2009527562A (ja) * 2006-02-21 2009-07-30 アムゲン インコーポレイティッド ホスホジエステラーゼ１０阻害剤としてのシンノリン誘導体
JP2009528365A (ja) * 2006-02-28 2009-08-06 アムゲン インコーポレイティッド ホスホジエステラーゼ１０阻害剤としてのシンノリン及びキナゾリン誘導体
AU2007223801A1 (en) * 2006-03-08 2007-09-13 Amgen Inc. Quinoline and isoquinoline derivatives as phosphodiesterase 10 inhibitors
JP2009532504A (ja) 2006-04-06 2009-09-10 グラクソ グループ リミテッド 抗菌薬
ATE481406T1 (de) 2006-04-06 2010-10-15 Glaxo Group Ltd Pyrrolochinoxalinonderivate als antibakterielle mittel
GB0613208D0 (en) 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
TW200819457A (en) 2006-08-30 2008-05-01 Actelion Pharmaceuticals Ltd Spiro antibiotic derivatives
CL2007003693A1 (es) * 2006-12-22 2008-06-27 Actelion Pharmaceuticals Ltd Compuestos derivados de pirido [3,2-b] [1,4] tiazina; composicion farmaceutica que contiene dichos compuestos; y su uso en el tratamiento de infecciones bacterianas.
CL2008001002A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
CL2008001003A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
KR101567096B1 (ko) 2007-04-20 2015-11-06 글락소 그룹 리미티드 항균제로서의 트리시클릭 질소 함유 화합물
ES2380398T3 (es) 2007-12-18 2012-05-11 Actelion Pharmaceuticals Ltd. Derivados 5-aminociclilmetil-oxazolidin-2-ona
EP2080761A1 (en) 2008-01-18 2009-07-22 Glaxo Group Limited Compounds
KR101592046B1 (ko) 2008-02-22 2016-02-05 액테리온 파마슈티칼 리미티드 옥사졸리디논 유도체
TW200944529A (en) 2008-04-15 2009-11-01 Actelion Pharmaceuticals Ltd Tricyclic antibiotics
US7741327B2 (en) 2008-04-16 2010-06-22 Hoffmann-La Roche Inc. Pyrrolidinone glucokinase activators
CN102046603B (zh) * 2008-06-03 2014-08-13 埃科特莱茵药品有限公司 作为抗细菌剂的[4-(1-氨基-乙基)-环己基]-甲基-胺及[6-(1-氨基-乙基)-四氢-吡喃-3-基]-甲基-胺衍生物
JP2012505866A (ja) 2008-10-17 2012-03-08 グラクソ グループ リミテッド 抗菌剤として使用される三環式窒素化合物
WO2010045987A1 (en) * 2008-10-23 2010-04-29 Glaxo Group Limited Substituted (aza) -1-methyl-1h-quin0lin-2-0nes as antibacterials
EP2346819B1 (en) 2008-11-17 2013-04-10 F. Hoffmann-La Roche AG Naphthylacetic acids
PT2376497E (pt) 2008-12-12 2013-11-21 Actelion Pharmaceuticals Ltd Derivados de 5-amino-2-(1-hidroxi-etil)-tetrahidropirano
US8318940B2 (en) 2009-01-15 2012-11-27 Glaxo Group Limited Naphthyridin-2 (1 H)-one compounds useful as antibacterials
AR076222A1 (es) * 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
US8394858B2 (en) 2009-12-03 2013-03-12 Novartis Ag Cyclohexane derivatives and uses thereof
US8178689B2 (en) 2010-06-17 2012-05-15 Hoffman-La Roche Inc. Tricyclic compounds
WO2012166586A1 (en) * 2011-05-27 2012-12-06 Temple University - Of The Commonwealth System Of Higher Education SUBSTITUTED 2-BENZYLIDENE-2H-BENZO[b][1,4]THIAZIN-3(4H)-ONES, DERIVATIVES THEREOF, AND THERAPEUTIC USES THEREOF
US8470884B2 (en) 2011-11-09 2013-06-25 Hoffmann-La Roche Inc. Alkenyl naphthylacetic acids
AR089929A1 (es) 2012-02-10 2014-10-01 Actelion Pharmaceuticals Ltd Proceso para manufacturar un derivado de naftiridina
JPWO2014157612A1 (ja) * 2013-03-29 2017-02-16 第一三共株式会社 （１ｓ，４ｓ，５ｓ）−４−ブロモ−６−オキサビシクロ［３．２．１］オクタン−７−オンの製造方法
CN104470898B (zh) 2013-05-13 2016-04-06 上海恒瑞医药有限公司 环烷基甲酸类衍生物、其制备方法及其在医药上的应用
BR112017003705B1 (pt) 2014-08-22 2022-07-12 Glaxosmithkline Intellectual Property Development Limited Compostos contendo nitrogênio tricíclicos para o tratamento de infecção por neisseria gonorrhoea
SI3209655T1 (sl) 2014-10-24 2020-11-30 Landos Biopharma, Inc. Terapevtiki na osnovi C-podobne lantionin sintetaze 2
UY36851A (es) * 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
EP3601267A1 (en) 2017-03-21 2020-02-05 Bayer Pharma Aktiengesellschaft 2-methyl-quinazolines
CA3083442A1 (en) 2017-11-30 2019-06-06 Landos Biopharma, Inc. Therapies with lanthionine c-like protein 2 ligands and cells prepared therewith
WO2019201848A1 (en) 2018-04-18 2019-10-24 Bayer Pharma Aktiengesellschaft 2-methyl-aza-quinazolines
WO2021076886A1 (en) 2019-10-18 2021-04-22 The Regents Of The University Of California 3-phenylsulphonyl-quinoline derivatives as agents for treating pathogenic blood vessels disorders
AU2020407645B2 (en) 2019-12-20 2022-10-06 Nimmune Biopharma, Inc. Lanthionine C-like protein 2 ligands, cells prepared therewith, and therapies using same
WO2022058344A1 (en) 2020-09-18 2022-03-24 Bayer Aktiengesellschaft Pyrido[2,3-d]pyrimidin-4-amines as sos1 inhibitors
EP4074317A1 (en) 2021-04-14 2022-10-19 Bayer AG Phosphorus derivatives as novel sos1 inhibitors
CN116102537B (zh) * 2021-11-10 2024-10-01 四川大学 一种喹啉酮类衍生物及其制备方法和用途
CN117568087B (zh) * 2024-01-16 2024-04-05 洛阳轻捷润滑油科技有限公司 一种长寿命汽车无极变速器油及其制备方法

Family Cites Families (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472404A (en) * 1982-08-16 1984-09-18 The Dow Chemical Company 8-Quinolinyl carbamates and their use as urinary tract antimicrobials
US4925877A (en) 1986-02-25 1990-05-15 Zaidanhojin Biseibutsu Kagaku Kenkyukai Physiologically active erbstatin analogue compounds and compositions
DE3874257T2 (de) 1987-03-11 1993-02-11 Kanegafuchi Chemical Ind Hydroxystyren-derivate.
ZA899436B (en) 1988-12-12 1990-08-29 Ciba Geigy Piperidine derivatives
EP0541486A1 (de) 1991-11-07 1993-05-12 Ciba-Geigy Ag Polycyclische Konjugate
US5263276A (en) 1992-09-21 1993-11-23 Fred Washington Fishing rod attachment
NZ273617A (en) 1993-10-01 1996-11-26 Ciba Geigy Ag N-phenyl-2-pyrimidineamine derivatives pharmaceutical compositions
JPH07179407A (ja) 1993-11-12 1995-07-18 Green Cross Corp:The 新規縮合環系化合物またはその塩、およびその医薬用途
CN1120156C (zh) 1994-06-17 2003-09-03 弗·哈夫曼-拉罗切有限公司 N,n′－二(喹啉－4－基)－二胺衍生物、其制备及作为抗疟药的应用
NZ296456A (en) 1994-11-14 1999-09-29 Warner Lambert Co 6-aryl pyrido[2,3-d]pyrimidines and naphthyridines; inhibition of protein tyrosine kinase mediated cellular proliferation
US5589482A (en) 1994-12-14 1996-12-31 Pfizer Inc. Benzo-thiophene estrogen agonists to treat prostatic hyperplasia
PT807630E (pt) * 1995-02-02 2003-08-29 Daiichi Seiyaku Co Compostos heterociclicos
KR19990008051A (ko) 1995-04-26 1999-01-25 히라타다다시 라디시콜 유도체
GB9514265D0 (en) 1995-07-13 1995-09-13 Wellcome Found Hetrocyclic compounds
TR199800854T2 (xx) 1995-11-16 1998-08-21 F.Hoffmann-La Roche Ag Antis�tma kinolin t�revleri.
US5707990A (en) 1996-01-30 1998-01-13 Ortho Pharmaceutical Corporation 2-substituted amino and thio alkyl benzoxazine antimicrobial agents
WO1997038984A1 (en) 1996-04-17 1997-10-23 Du Pont Pharmaceuticals Company N-(amidinophenyl)-n'-(subst.)-3h-2,4-benzodiazepin-3-one derivatives as factor xa inhibitors
HRP970371A2 (en) 1996-07-13 1998-08-31 Kathryn Jane Smith Heterocyclic compounds
PT912559E (pt) 1996-07-13 2003-03-31 Glaxo Group Ltd Compostos heterociclicos fundidos como inibidores de proteina tirosina quinase
JP2001504456A (ja) 1996-10-30 2001-04-03 メルク エンド カンパニー インコーポレーテッド インテグリン拮抗薬
TW523506B (en) 1996-12-18 2003-03-11 Ono Pharmaceutical Co Sulfonamide or carbamide derivatives and drugs containing the same as active ingredients
US6187797B1 (en) 1996-12-23 2001-02-13 Dupont Pharmaceuticals Company Phenyl-isoxazoles as factor XA Inhibitors
CZ225699A3 (cs) 1996-12-23 2000-09-13 Du Pont Pharmaceuticals Company Dusíkaté heteroaromatické sloučeniny jako inhibitory faktoru Xa
US6103905A (en) * 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
ES2201674T3 (es) 1998-01-26 2004-03-16 Smithkline Beecham Plc Derivados de quinolina con propiedades antibacterianas.
HUP0101275A3 (en) 1998-03-26 2002-12-28 Japan Tobacco Inc Amide derivatives and pharmaceutical compositions containing them as nociceptin antagonists
SE9802206D0 (sv) 1998-06-22 1998-06-22 Astra Pharma Inc Novel compounds
GB9822450D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
GB9822440D0 (en) 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
JP2002532493A (ja) 1998-12-17 2002-10-02 エフ．ホフマン−ラ ロシュ アーゲー Ｊｎｋプロテインキナーゼ阻害剤としての４−アリールオキシインドール
AU2437900A (en) 1999-01-20 2000-08-07 Smithkline Beecham Plc Piperidinylquinolines as protein tyrosine kinase inhibitors
WO2000045635A1 (en) 1999-02-08 2000-08-10 Lion Bioscience Ag Thiazole derivatives and combinatorial libraries thereof
GB9910580D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
GB9910579D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
GB9910577D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
GB9914074D0 (en) * 1999-06-16 1999-08-18 Btg Int Ltd Tibial component
GB9914486D0 (en) 1999-06-21 1999-08-18 Smithkline Beecham Plc Medicaments
AU5567000A (en) 1999-06-24 2001-01-09 Toray Industries, Inc. Alpha1b-adrenergic receptor antagonists
GB9917408D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB9917406D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
HK1052497B (zh) 1999-09-17 2007-03-02 千禧药品公司 苯甲酸胺和相关的因子xa抑制剂
FR2798656B1 (fr) 1999-09-17 2004-12-17 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent
DE19955476A1 (de) 1999-11-18 2001-05-23 Boehringer Ingelheim Pharma Bis-basische Verbindungen als Tryptase-Inhibitoren, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
CN1481377A (zh) 2000-03-17 2004-03-10 ����˹�ж�-����˹˹����ҩƷ��˾ 作为基质金属蛋白酶和TNF-α的抑制剂的环β-氨基酸衍生物
AU2001249262A1 (en) 2000-03-20 2001-10-03 Sepracor, Inc. Therapeutic compounds for the treatment of asthma and allergy, and methods of use thereof
WO2001072712A1 (en) 2000-03-24 2001-10-04 Cor Therapeutics, Inc. ISOQUINOLONE INHIBITORS OF FACTOR Xa
US6548517B2 (en) 2000-03-24 2003-04-15 Millennium Pharmaceuticals, Inc. Oxindole inhibitors of factor Xa
TWI290136B (en) 2000-04-05 2007-11-21 Daiichi Seiyaku Co Ethylenediamine derivatives
CN1452619A (zh) * 2000-07-26 2003-10-29 史密斯克莱·比奇曼公司 具有抗细菌活性的氨基哌啶喹啉和它们的氮杂等排的类似物
EP1320529B1 (en) 2000-09-21 2006-05-24 Smithkline Beecham Plc Quinoline derivatives as antibacterials
FR2816618B1 (fr) 2000-11-15 2002-12-27 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
GB0031088D0 (en) 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0031086D0 (en) 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
FR2822154B1 (fr) 2001-03-13 2005-10-21 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
US7312212B2 (en) 2002-01-29 2007-12-25 Glaxo Group Limited Aminopiperidine derivatives
US7109213B2 (en) 2002-01-29 2006-09-19 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
US6818772B2 (en) * 2002-02-22 2004-11-16 Abbott Laboratories Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
TW200406413A (en) * 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
FR2844270B1 (fr) 2002-09-11 2006-05-19 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur procede et intermediaires de preparation et les compositions qui les contiennent
FR2844268B1 (fr) 2002-09-11 2004-10-22 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent
ATE463494T1 (de) 2002-10-10 2010-04-15 Morphochem Ag Komb Chemie Neue verbindungen mit antibakterieller aktivität
TW200427688A (en) * 2002-12-18 2004-12-16 Glaxo Group Ltd Antibacterial agents
DE10316081A1 (de) 2003-04-08 2004-10-21 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität

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AR038172A1 (es) 2005-01-05
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CO5540344A2 (es) 2005-07-29
BR0210016A (pt) 2004-06-15
JP2010031057A (ja) 2010-02-12
TWI232219B (en) 2005-05-11
JP4463565B2 (ja) 2010-05-19
EP1399443B1 (en) 2007-12-12
ZA200308696B (en) 2004-05-21
ES2298439T3 (es) 2008-05-16
NO20035190D0 (no) 2003-11-21
AU2002367697A1 (en) 2003-10-27
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PL367079A1 (en) 2005-02-21
WO2003087098A1 (en) 2003-10-23
ATE380812T1 (de) 2007-12-15
CZ20033202A3 (cs) 2004-08-18
HUP0400017A2 (hu) 2004-06-28
EP1399443A1 (en) 2004-03-24
IL158869A0 (en) 2004-05-12
CA2448525A1 (en) 2003-10-23
US20070135422A1 (en) 2007-06-14
DE60224039T2 (de) 2008-11-27
US7141564B2 (en) 2006-11-28
DE60224039D1 (de) 2008-01-24
KR20040010654A (ko) 2004-01-31

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