FR2676234B1 - Procede et appareil pour la regulation de la concentration de source de carbone dans la culture aerobie d'un micro-organisme. - Google Patents

Procede et appareil pour la regulation de la concentration de source de carbone dans la culture aerobie d'un micro-organisme.

Info

Publication number
FR2676234B1
FR2676234B1 FR9202315A FR9202315A FR2676234B1 FR 2676234 B1 FR2676234 B1 FR 2676234B1 FR 9202315 A FR9202315 A FR 9202315A FR 9202315 A FR9202315 A FR 9202315A FR 2676234 B1 FR2676234 B1 FR 2676234B1
Authority
FR
France
Prior art keywords
microorganism
regulating
concentration
carbon source
aerobic culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9202315A
Other languages
English (en)
Other versions
FR2676234A1 (fr
Inventor
Harufumi Miwa
Minoru Tsuruta
Koji Tamura
Yosuke Koyama
Osamu Tosaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP12699291A external-priority patent/JP3074781B2/ja
Priority claimed from JP27793891A external-priority patent/JP2932791B2/ja
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of FR2676234A1 publication Critical patent/FR2676234A1/fr
Application granted granted Critical
Publication of FR2676234B1 publication Critical patent/FR2676234B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Sustainable Development (AREA)
  • Computer Hardware Design (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
FR9202315A 1990-11-30 1992-02-27 Procede et appareil pour la regulation de la concentration de source de carbone dans la culture aerobie d'un micro-organisme. Expired - Fee Related FR2676234B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP33968790 1990-11-30
JP12699291A JP3074781B2 (ja) 1991-03-12 1991-03-12 発酵法によるｌ−リジンの製造法
JP27793891A JP2932791B2 (ja) 1990-11-30 1991-10-24 微生物好気培養における炭素源濃度の制御方法及び装置

Publications (2)

Publication Number Publication Date
FR2676234A1 FR2676234A1 (fr) 1992-11-13
FR2676234B1 true FR2676234B1 (fr) 1996-12-20

Family

ID=27315443

Family Applications (2)

Application Number Title Priority Date Filing Date
FR9114851A Expired - Lifetime FR2669935B1 (fr) 1990-11-30 1991-11-29 Procede et appareil pour la regulation de la concentration de source de carbone dans la culture aerobie d'un micro-organisme.
FR9202315A Expired - Fee Related FR2676234B1 (fr) 1990-11-30 1992-02-27 Procede et appareil pour la regulation de la concentration de source de carbone dans la culture aerobie d'un micro-organisme.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR9114851A Expired - Lifetime FR2669935B1 (fr) 1990-11-30 1991-11-29 Procede et appareil pour la regulation de la concentration de source de carbone dans la culture aerobie d'un micro-organisme.

Country Status (6)

Country Link
US (2) US5912113A (fr)
BE (1) BE1008008A3 (fr)
BR (1) BR9105208A (fr)
FR (2) FR2669935B1 (fr)
IT (1) IT1256566B (fr)
MY (1) MY121534A (fr)

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EP0952212A1 (fr) * 1998-04-20 1999-10-27 Rohner AG Procédé pour la culture aérobique de microorganismes
US6284453B1 (en) * 1999-09-29 2001-09-04 Steven Anthony Siano Method for controlling fermentation growth and metabolism
AR026743A1 (es) * 1999-12-09 2003-02-26 Pharmacia Ab Produccion de peptidos
SE9904502D0 (sv) * 1999-12-09 1999-12-09 Pharmacia & Upjohn Ab Production of peptides
JP4362959B2 (ja) * 2000-08-24 2009-11-11 味の素株式会社 塩基性アミノ酸の製造方法
AU2002306481A1 (en) * 2001-02-14 2002-08-28 Gadi Steiner Methods of controlling microorganism fermentation
US6955892B2 (en) * 2002-11-12 2005-10-18 Akzo Nobel N.V. Feeding processes for fermentation
US20040115304A1 (en) * 2002-12-16 2004-06-17 Frank Dubner Feesdstuffs additives containing L-lysine with improved abrasion resistance, and process for their production
EP1649031A1 (fr) * 2003-08-01 2006-04-26 Degussa AG Procede de preparation de l-threonine
WO2005014841A1 (fr) * 2003-08-01 2005-02-17 Degussa Ag Procede de preparation de l-threonine
WO2005014842A1 (fr) * 2003-08-01 2005-02-17 Degussa Ag Procede de preparation de l-threonine
DE102004029639A1 (de) * 2003-08-12 2005-03-24 Degussa Ag Verfahren zur Herstellung von L-Threonin
WO2005021771A2 (fr) * 2003-08-29 2005-03-10 Degussa Ag Procede de production de l-lysine
WO2005021774A1 (fr) * 2003-08-29 2005-03-10 Degussa Ag Procede de preparation de l-lysine
WO2005021773A1 (fr) * 2003-08-29 2005-03-10 Degussa Ag Procede pour preparer de la l-lysine
WO2005021772A1 (fr) * 2003-08-29 2005-03-10 Degussa Ag Procede de preparation de l-lysine
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JP2010017082A (ja) 2006-10-10 2010-01-28 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2010110216A (ja) 2007-02-20 2010-05-20 Ajinomoto Co Inc Ｌ−アミノ酸または核酸の製造方法
JP2010110217A (ja) 2007-02-22 2010-05-20 Ajinomoto Co Inc Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
EP2192170B1 (fr) 2007-09-04 2017-02-15 Ajinomoto Co., Inc. Microorganisme produisant des acides aminés et procédé de production des acides aminés
DE102008002210A1 (de) 2008-06-04 2009-12-10 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von Erythropoietin
JP2012029565A (ja) 2008-11-27 2012-02-16 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
WO2010084995A2 (fr) 2009-01-23 2010-07-29 Ajinomoto Co.,Inc. Procédé de production d'un acide l-aminé
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JP2013074795A (ja) 2010-02-08 2013-04-25 Ajinomoto Co Inc 変異型ｒｐｓＡ遺伝子及びＬ−アミノ酸の製造法
US20120156669A1 (en) 2010-05-20 2012-06-21 Pond Biofuels Inc. Biomass Production
US8889400B2 (en) 2010-05-20 2014-11-18 Pond Biofuels Inc. Diluting exhaust gas being supplied to bioreactor
US8969067B2 (en) 2010-05-20 2015-03-03 Pond Biofuels Inc. Process for growing biomass by modulating supply of gas to reaction zone
US8940520B2 (en) 2010-05-20 2015-01-27 Pond Biofuels Inc. Process for growing biomass by modulating inputs to reaction zone based on changes to exhaust supply
US11512278B2 (en) 2010-05-20 2022-11-29 Pond Technologies Inc. Biomass production
JP2014036576A (ja) 2010-12-10 2014-02-27 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
DE102010063033B4 (de) * 2010-12-14 2013-10-24 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Verfahren zur Inbetriebnahme eines Messgeräts
US20120276633A1 (en) 2011-04-27 2012-11-01 Pond Biofuels Inc. Supplying treated exhaust gases for effecting growth of phototrophic biomass
US9534261B2 (en) 2012-10-24 2017-01-03 Pond Biofuels Inc. Recovering off-gas from photobioreactor
ES2656337T3 (es) 2013-03-29 2018-02-26 Roquette Frères Procedimiento de enriquecimiento en proteínas de la biomasa de microalgas
FR3008991B1 (fr) * 2013-07-26 2016-11-04 Roquette Freres Procede de fermentation de chlorelles en mode discontinu alimente par apports sequentiels et automatises en glucose
KR20160045066A (ko) 2013-08-23 2016-04-26 로께뜨프레르 산소의 가용성을 제어하여 나쁜 특색을 갖지 않는, 지질이 풍부한 미세조류의 바이오매스 미분의 산업적 생산 방법
JP6519476B2 (ja) 2013-10-23 2019-05-29 味の素株式会社 目的物質の製造法
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JP2019062742A (ja) 2016-02-24 2019-04-25 味の素株式会社 Ｌ−アミノ酸の製造法
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EP3456833A1 (fr) 2017-09-18 2019-03-20 Evonik Degussa GmbH Méthode de production d'acides aminés l par fermentation
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EP3498853A1 (fr) 2017-12-14 2019-06-19 Evonik Degussa GmbH Procédé de production de l-lysine par fermentation
EP3594355A1 (fr) 2018-07-12 2020-01-15 Evonik Operations GmbH Procédé de production de l-lysine par fermentation
EP3599282B1 (fr) 2018-07-24 2021-03-17 Evonik Operations GmbH Procédé de production de l-lysine par fermentation
RU2019128538A (ru) 2018-09-26 2021-03-11 Эвоник Оперейшенс ГмбХ Способ ферментативного получения l-лизина
CN111099740B (zh) * 2018-10-26 2022-06-07 中国石油化工股份有限公司 一种化能自养微生物培养过程的补料控制方法
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CN111349573B (zh) * 2018-12-24 2022-11-18 中粮生物科技股份有限公司 一种酵母菌的高密度发酵方法
CN112746030B (zh) * 2019-10-30 2023-02-03 中国石油化工股份有限公司 一种硝化细菌的培养方法
WO2023041425A1 (fr) 2021-09-20 2023-03-23 Evonik Operations Gmbh Procédé de production fermentative de l-lysine au moyen de souches de c. glutamicum exprimant des protéines répresseurs de gluconate modifiées gntr1 et gntr2

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Also Published As

Publication number Publication date
FR2676234A1 (fr) 1992-11-13
FR2669935A1 (fr) 1992-06-05
BR9105208A (pt) 1992-07-21
FR2669935B1 (fr) 1996-08-02
ITMI913198A0 (it) 1991-11-29
BE1008008A3 (fr) 1995-12-12
ITMI913198A1 (it) 1993-05-29
US5912113A (en) 1999-06-15
US6025169A (en) 2000-02-15
MY121534A (en) 2006-02-28
IT1256566B (it) 1995-12-11

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