FR08C0052I2 - Derives de 6-mercapto-cyclodextrine: agents d'inversion du blocage neuromusculaire provoque par des substances medicamenteuses - Google Patents
Derives de 6-mercapto-cyclodextrine: agents d'inversion du blocage neuromusculaire provoque par des substances medicamenteusesInfo
- Publication number
- FR08C0052I2 FR08C0052I2 FR08C0052C FR08C0052C FR08C0052I2 FR 08C0052 I2 FR08C0052 I2 FR 08C0052I2 FR 08C0052 C FR08C0052 C FR 08C0052C FR 08C0052 C FR08C0052 C FR 08C0052C FR 08C0052 I2 FR08C0052 I2 FR 08C0052I2
- Authority
- FR
- France
- Prior art keywords
- mercapto
- agents
- drug substances
- cyclodextrin derivatives
- blockage caused
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003795 chemical substances by application Substances 0.000 title 1
- 229940088679 drug related substance Drugs 0.000 title 1
- 230000002232 neuromuscular Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99309558 | 1999-11-29 | ||
PCT/EP2000/011789 WO2001040316A1 (fr) | 1999-11-29 | 2000-11-23 | Derives de 6-mercapto-cyclodextrine: agents d"inversion du blocage neuromusculaire provoque par des substances medicamenteuses |
EP00993261A EP1259550B1 (fr) | 1999-11-29 | 2000-11-23 | Derives de 6-mercapto-cyclodextrine: agents d'inversion du blocage neuromusculaire provoque par des substances medicamenteuses |
Publications (2)
Publication Number | Publication Date |
---|---|
FR08C0052I1 FR08C0052I1 (fr) | 2009-02-27 |
FR08C0052I2 true FR08C0052I2 (fr) | 2009-12-18 |
Family
ID=8241767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR08C0052C Active FR08C0052I2 (fr) | 1999-11-29 | 2008-12-30 | Derives de 6-mercapto-cyclodextrine: agents d'inversion du blocage neuromusculaire provoque par des substances medicamenteuses |
Country Status (34)
Country | Link |
---|---|
US (3) | USRE44733E1 (fr) |
EP (1) | EP1259550B1 (fr) |
JP (2) | JP3880041B2 (fr) |
KR (1) | KR100716524B1 (fr) |
CN (1) | CN1188428C (fr) |
AR (1) | AR026605A1 (fr) |
AT (1) | ATE288450T1 (fr) |
AU (1) | AU776536B2 (fr) |
BE (1) | BE2008C047I2 (fr) |
BR (1) | BRPI0015947B8 (fr) |
CA (1) | CA2390463C (fr) |
CO (1) | CO5251450A1 (fr) |
CY (1) | CY2008018I2 (fr) |
CZ (1) | CZ298206B6 (fr) |
DE (2) | DE122008000068I2 (fr) |
DK (1) | DK1259550T3 (fr) |
ES (1) | ES2237496T3 (fr) |
FR (1) | FR08C0052I2 (fr) |
HK (1) | HK1049489A1 (fr) |
HU (1) | HU227451B1 (fr) |
IL (1) | IL149423A0 (fr) |
LU (1) | LU91501I2 (fr) |
MX (1) | MXPA02004940A (fr) |
NL (1) | NL300356I2 (fr) |
NO (2) | NO328790B1 (fr) |
NZ (1) | NZ518752A (fr) |
PE (1) | PE20010902A1 (fr) |
PL (1) | PL203012B1 (fr) |
PT (1) | PT1259550E (fr) |
RU (1) | RU2260013C2 (fr) |
SK (1) | SK286282B6 (fr) |
TW (1) | TWI242015B (fr) |
WO (1) | WO2001040316A1 (fr) |
ZA (1) | ZA200203538B (fr) |
Families Citing this family (76)
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US6744471B1 (en) * | 1997-12-05 | 2004-06-01 | Olympus Optical Co., Ltd | Electronic camera that synthesizes two images taken under different exposures |
TWI242015B (en) | 1999-11-29 | 2005-10-21 | Akzo Nobel Nv | 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block |
EP1629845A3 (fr) * | 2000-11-02 | 2006-03-22 | Akzo Nobel N.V. | Utilisation d'agents séquestrants de cortisol dans le cadre du traitement de troubles liés à l'hypercortisolémie |
CA2543443A1 (fr) | 2003-10-31 | 2005-05-12 | The University Of Kansas | Derives de sulfoalkyl ether-alkyl ether cyclodextrines |
EP1735326A4 (fr) | 2004-01-29 | 2011-04-20 | Pinnacle Pharmaceuticals | Derives de beta-cyclodextrine et leur utilisation contre la toxine letale d'anthrax |
SI2708225T1 (sl) | 2004-04-23 | 2019-05-31 | Cydex Pharmaceuticals, Inc. | Formulacija DPI, ki vsebuje sulfoalkil eter ciklodekstrin |
WO2006083678A2 (fr) | 2005-01-28 | 2006-08-10 | Pinnacle Pharmaceuticals, Inc. | DERIVES DE ß -CYCLODEXTRINE COMME AGENTS ANTIBACTERIENS |
US7629331B2 (en) | 2005-10-26 | 2009-12-08 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
PL2335707T3 (pl) | 2005-10-26 | 2015-10-30 | Cydex Pharmaceuticals Inc | Kompozycje eteru sulfoalkilowego cyklodekstryny i sposoby ich wytwarzania |
US20090069412A1 (en) * | 2007-09-09 | 2009-03-12 | Protia, Llc | Deuterium-enriched sugammadex |
US7635773B2 (en) | 2008-04-28 | 2009-12-22 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions |
US7938283B2 (en) * | 2008-06-20 | 2011-05-10 | Grainpro, Inc. | System and method for hermetic storage of agricultural commodities during shipping |
WO2010053487A1 (fr) | 2008-11-07 | 2010-05-14 | Cydex Pharmaceuticals, Inc. | Composition contenant de la sulfoalkyl éther cyclodextrine et du latanoprost |
CN101591402B (zh) * | 2009-05-05 | 2011-11-30 | 杭州奥默医药技术有限公司 | 6-脱氧砜类环糊精衍生物及其制备方法 |
US8492538B1 (en) | 2009-06-04 | 2013-07-23 | Jose R. Matos | Cyclodextrin derivative salts |
DE102010012281A1 (de) * | 2010-03-22 | 2011-09-22 | Fresenius Medical Care Deutschland Gmbh | Pharmazeutische Zusammensetzungen enthaltend substituiertes 6-Deoxy-6-sulfanylcyclodextrin |
CN101864003B (zh) * | 2010-06-11 | 2012-05-02 | 漆又毛 | 一种6-脱氧硫醚氨基酸环糊精衍生物的合成方法 |
ES2551585T3 (es) * | 2010-08-25 | 2015-11-20 | Davuluri, Ramamohan Rao | Procedimiento mejorado para la preparación de Sugammadex |
CN102060941B (zh) | 2010-11-26 | 2012-12-26 | 漆又毛 | 6-脱氧α-氨基酸衍生物环糊精及制备和应用 |
CN104271605B (zh) | 2012-02-15 | 2017-07-25 | 锡德克斯药物公司 | 环糊精衍生物的制造方法 |
RU2747757C2 (ru) | 2012-02-28 | 2021-05-13 | Сидекс Фармасьютикалс, Инк. | Композиции алкилированного циклодекстрина и способы их получения и применения |
JP5892847B2 (ja) * | 2012-04-27 | 2016-03-23 | Dowaホールディングス株式会社 | シクロデキストリンとシリカ含有物質との複合材料、及びその製造方法、並びにガス吸着剤 |
GB201211153D0 (en) * | 2012-06-22 | 2012-08-08 | Farmhispania | Pharmaceutical compositions |
MY181829A (en) | 2012-10-22 | 2021-01-08 | Cydex Pharmaceuticals Inc | Alkylated cyclodextrin compositions and processes for preparing and using the same |
WO2014125501A1 (fr) | 2013-02-14 | 2014-08-21 | Neuland Laboratories Limited | Procédé amélioré pour la préparation de sugammadex sodique |
WO2015179963A1 (fr) | 2014-05-29 | 2015-12-03 | Uti Limited Partnership | Dendrimères polyanioniques et non ioniques à base de cyclodextrine |
CN107073007A (zh) | 2014-06-26 | 2017-08-18 | 丸石制药株式会社 | 具有改进的稳定性的罗库溴铵制剂 |
CN105348412B (zh) * | 2014-08-22 | 2018-06-05 | 江苏恩华药业股份有限公司 | 一种舒更葡糖钠的纯化方法 |
JP6914188B2 (ja) | 2014-08-22 | 2021-08-04 | サイデックス・ファーマシューティカルズ・インコーポレイテッド | 分画アルキル化シクロデキストリン組成物ならびにその調製方法および使用方法 |
MX2017011966A (es) | 2015-03-19 | 2018-06-06 | Cydex Pharmaceuticals Inc | Composiciones que contienen silimarina y sulfoalquil eter ciclodextrina y metodos de uso de las mismas. |
CN104844732B (zh) * | 2015-03-27 | 2017-05-03 | 山东滨州智源生物科技有限公司 | 一种舒更葡糖钠的制备方法 |
AU2015390471A1 (en) * | 2015-04-08 | 2017-11-09 | John KLASSEN | Pharmaceutical compositions of polyanionic and non-ionic cyclodextrin-based dendrimers and uses thereof |
JP6946275B2 (ja) * | 2015-05-29 | 2021-10-06 | ラクシュミ・プラサド・アラパルティLakshmi Prasad ALAPARTHI | スガマデクスおよびその中間体の製造方法 |
CN104922693A (zh) * | 2015-06-19 | 2015-09-23 | 南开大学 | 一种阴离子型环糊精与抗癌药物包合物及制备方法 |
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CN108291057B (zh) | 2015-11-25 | 2021-07-13 | 费森尤斯卡比依普莎姆有限责任公司 | 全氯代-γ-环糊精的晶体形式 |
KR102251673B1 (ko) * | 2015-11-25 | 2021-05-13 | 프레제니우스 카비 입섬 에스. 알. 엘. | 슈감마덱스 및 이의 중간체 제조를 위한 개선된 방법 |
EP3733717A3 (fr) | 2016-03-22 | 2020-12-30 | Fresenius Kabi iPSUM S.r.l. | Procédé amélioré pour la préparation de sugammadex |
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CN107778383B (zh) | 2016-08-24 | 2020-03-10 | 王炳永 | 一种舒更葡糖钠的精制方法 |
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JP4249282B2 (ja) | 1998-02-27 | 2009-04-02 | 日本食品化工株式会社 | 新規シクロデキストリン誘導体及びその製造方法 |
DE69942317D1 (de) | 1998-05-29 | 2010-06-10 | Neurosciences Res Found | Schmerzlinderung mit anandamide |
WO2001012202A2 (fr) | 1999-08-13 | 2001-02-22 | Akzo Nobel N.V. | Utilisation d'agents chimiques chelatants comme agents de neutralisation du blocage neuromusculaire provoque par des medicaments |
TWI242015B (en) | 1999-11-29 | 2005-10-21 | Akzo Nobel Nv | 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block |
US20020111377A1 (en) | 2000-12-22 | 2002-08-15 | Albany College Of Pharmacy | Transdermal delivery of cannabinoids |
WO2002064635A1 (fr) | 2001-02-14 | 2002-08-22 | Akzo Nobel N.V. | Derives de cyclodextrine 2-alkylee : agents d'inversion du blocage neuromusculaire d'origine medicamenteuse |
TW200402417A (en) | 2002-06-21 | 2004-02-16 | Akzo Nobel Nv | 1-[(Indol-3-yl)carbonyl]piperazine derivatives |
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2000
- 2000-11-08 TW TW089123585A patent/TWI242015B/zh active
- 2000-11-23 US US13/432,742 patent/USRE44733E1/en active Active
- 2000-11-23 DE DE122008000068C patent/DE122008000068I2/de active Active
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- 2000-11-23 US US10/148,307 patent/US6670340B1/en not_active Ceased
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2003
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2006
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- 2008-12-30 FR FR08C0052C patent/FR08C0052I2/fr active Active
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2010
- 2010-11-10 NO NO2010019C patent/NO2010019I2/no unknown
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