FR08C0013I1 - - Google Patents
Info
- Publication number
- FR08C0013I1 FR08C0013I1 FR08C0013C FR08C0013I1 FR 08C0013 I1 FR08C0013 I1 FR 08C0013I1 FR 08C0013 C FR08C0013 C FR 08C0013C FR 08C0013 I1 FR08C0013 I1 FR 08C0013I1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9911183.3A GB9911183D0 (en) | 1999-05-13 | 1999-05-13 | Treatment of cancers |
| GBGB9911346.6A GB9911346D0 (en) | 1999-05-14 | 1999-05-14 | Treatment of cancers |
| GBGB9918534.0A GB9918534D0 (en) | 1999-08-05 | 1999-08-05 | Treatment of cancers |
| GBGB9927005.0A GB9927005D0 (en) | 1999-11-15 | 1999-11-15 | Treatment of cancers |
| GBGB9927106.6A GB9927106D0 (en) | 1999-11-16 | 1999-11-16 | Cancer treatment |
| GB0007637A GB0007637D0 (en) | 2000-03-29 | 2000-03-29 | Antitumour compound |
| EP00927584A EP1176964B8 (en) | 1999-05-13 | 2000-05-15 | Uses of et743 for treating cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR08C0013I1 true FR08C0013I1 (enExample) | 2008-05-30 |
| FR08C0013I2 FR08C0013I2 (fr) | 2009-10-30 |
Family
ID=27546594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR08C0013C Active FR08C0013I2 (fr) | 1999-05-13 | 2008-04-16 | Utilisation de et743 en thérapie combinée avec dexaméthasone pour traiter le cancer |
Country Status (32)
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY164077A (en) | 1999-05-13 | 2017-11-30 | Pharma Mar Sa | Compositions and uses of et743 for treating cancer |
| MXPA02011319A (es) | 2000-05-15 | 2003-06-06 | Pharma Mar Sa | Analogos antitumorales de ecteinascidina 743. |
| WO2002036135A2 (en) * | 2000-11-06 | 2002-05-10 | Pharma Mar, S.A. | Compositions for antitumour treatment containing ecteinascidin 743 |
| GB0117402D0 (en) * | 2001-07-17 | 2001-09-05 | Pharma Mar Sa | New antitumoral derivatives of et-743 |
| PL368458A1 (en) * | 2001-10-19 | 2005-03-21 | Pharmamar S.A. | Improved use of antitumoral compound in cancer therapy |
| GB0202544D0 (en) | 2002-02-04 | 2002-03-20 | Pharma Mar Sa | The synthesis of naturally occuring ecteinascidins and related compounds |
| GB0312407D0 (en) * | 2003-05-29 | 2003-07-02 | Pharma Mar Sau | Treatment |
| GB0324201D0 (en) * | 2003-10-15 | 2003-11-19 | Pharma Mar Sau | Improved antitumoral combinations |
| JP2007511499A (ja) * | 2003-11-13 | 2007-05-10 | ファーマ・マール・エス・アー・ウー | コンビネーション |
| GB0326486D0 (en) * | 2003-11-14 | 2003-12-17 | Pharma Mar Sau | Combination treatment |
| JP2007511509A (ja) * | 2003-11-14 | 2007-05-10 | ファルマ・マール・ソシエダード・アノニマ | Ｅｔ−７４３およびパクリタキセルの使用を含むガンの併用療法 |
| JP2008505862A (ja) * | 2004-07-09 | 2008-02-28 | ファルマ、マール、ソシエダード、アノニマ | 予後分子マーカー |
| RS50822B (sr) * | 2004-10-26 | 2010-08-31 | Pharma Mar S.A., Sociedad Unipersonal | Pegilovani lipozomalni doksorubicin u kombinaciji sa ekteinescidinom 743 |
| KR101188691B1 (ko) * | 2004-10-29 | 2012-10-09 | 파르마 마르 에스.에이. | 엑티나시딘 및 디사카라이드를 포함하는 제제 |
| GB0522082D0 (en) * | 2005-10-31 | 2005-12-07 | Pharma Mar Sa | Formulations |
| WO2007134203A2 (en) * | 2006-05-12 | 2007-11-22 | Pharma Mar, S.A. | Anticancer treatments with a combination of docetaxel and ecteinascidin |
| WO2009050303A1 (en) * | 2007-10-19 | 2009-04-23 | Pharma Mar, S.A. | Prognostic molecular markers for et-743 treatment |
| RU2738741C2 (ru) * | 2016-02-04 | 2020-12-16 | Цзянсу Хэнжуй Медицин Ко., Лтд. | Инъекционная фармацевтическая композиция, включающая трабектедин, для применения вне желудочно-кишечного тракта и способ её получения |
| LT3615544T (lt) | 2017-04-27 | 2023-05-10 | Pharma Mar S.A. | Priešnavikiniai junginiai |
| WO2020239478A1 (en) | 2019-05-28 | 2020-12-03 | Pharma Mar, S.A. | Trabectedin for treating sarcomas based on genomic markers |
| CN112574234B (zh) * | 2019-09-27 | 2022-05-24 | 江苏恒瑞医药股份有限公司 | 一种海鞘素衍生物的制备方法 |
| CA3176956A1 (en) | 2020-04-15 | 2021-10-21 | Ever Valinject Gmbh | Composition comprising trabectedin and an amino acid |
| EP3960177A1 (en) * | 2020-08-26 | 2022-03-02 | Anturec Pharmaceuticals GmbH | Composition comprising ttf-ngr for use in treating soft-tissue sarcoma |
| IL308389A (en) * | 2021-05-19 | 2024-01-01 | Pharma Mar Sa | Dosing regimens for acubactadine |
| US12303506B2 (en) | 2022-01-20 | 2025-05-20 | Extrovis Ag | Trabectedin composition |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089273A (en) | 1986-06-09 | 1992-02-18 | Board Of Trustees Of The University Of Illinois | Ecteinascidins 729, 743, 745, 759A, 759B and 770 |
| EP0309477B1 (en) * | 1986-06-09 | 1991-11-06 | The Board Of Trustees Of The University Of Illinois | Ecteinascidins 729, 743, 745, 759a, 759b and 770 |
| US5149804A (en) * | 1990-11-30 | 1992-09-22 | The Board Of Trustees Of The University Of Illinois | Ecteinascidins 736 and 722 |
| US5256663A (en) * | 1986-06-09 | 1993-10-26 | The Board Of Trustees Of The University Of Illinois | Compositions comprising ecteinascidins and a method of treating herpes simplex virus infections therewith |
| DE3635711A1 (de) | 1986-10-21 | 1988-04-28 | Knoll Ag | 5-nitrobenzo(de)isochinolin-1,3-dione, ihre herstellung und verwendung |
| GB8805268D0 (en) * | 1988-03-04 | 1988-04-07 | Glaxo Group Ltd | Medicaments |
| GB9101221D0 (en) * | 1991-01-19 | 1991-02-27 | Smithkline Beecham Plc | Pharmaceuticals |
| US5721352A (en) | 1991-02-19 | 1998-02-24 | University Of Florida Research Foundation | Entomopoxvirus expression system |
| FR2697752B1 (fr) | 1992-11-10 | 1995-04-14 | Rhone Poulenc Rorer Sa | Compositions antitumorales contenant des dérivés du taxane. |
| US5891704A (en) * | 1992-11-19 | 1999-04-06 | Anticancer, Inc. | Method to produce high levels of methioninase |
| WO1994026250A1 (en) * | 1993-05-14 | 1994-11-24 | Depotech Corporation | Method for treating neurological disorders |
| US5478932A (en) | 1993-12-02 | 1995-12-26 | The Board Of Trustees Of The University Of Illinois | Ecteinascidins |
| US20040059112A1 (en) | 1994-02-18 | 2004-03-25 | Rinehart Kenneth L. | Ecteinascidins |
| US5919816A (en) * | 1994-11-14 | 1999-07-06 | Bionumerik Pharmaceuticals, Inc. | Formulations and methods of reducing toxicity of antineoplastic agents |
| GB9508195D0 (en) | 1995-04-20 | 1995-06-07 | Univ British Columbia | Novel biologically active compounds and compositions,their use and derivation |
| US5721362A (en) * | 1996-09-18 | 1998-02-24 | President And Fellows Of Harvard College | Process for producing ecteinascidin compounds |
| EP1920773B1 (en) * | 1996-11-05 | 2011-01-05 | The Children's Medical Center Corporation | Thalidomide and dexamethasone for the treatment of tumors |
| IL123740A0 (en) * | 1997-03-28 | 1998-10-30 | Pfizer | NK-1 receptor antagonists for the treatment of delayed emesis |
| US5985876A (en) * | 1997-04-15 | 1999-11-16 | Univ Illinois | Nucleophile substituted ecteinascidins and N-oxide ecteinascidins |
| DE19720312A1 (de) * | 1997-05-15 | 1998-11-19 | Hoechst Ag | Zubereitung mit erhöhter in vivo Verträglichkeit |
| GB9801231D0 (en) * | 1997-06-05 | 1998-03-18 | Merck & Co Inc | A method of treating cancer |
| BR9909488B1 (pt) | 1998-04-06 | 2011-02-08 | ecteinascidinas semi-sintéticas e composição farmacêutica. | |
| IL139607A0 (en) * | 1998-05-11 | 2002-02-10 | Pharma Mar Sa | Metabolites of ecteinascidin 743 |
| US6124292A (en) | 1998-09-30 | 2000-09-26 | President And Fellows Of Harvard College | Synthetic analogs of ecteinascidin-743 |
| MY164077A (en) | 1999-05-13 | 2017-11-30 | Pharma Mar Sa | Compositions and uses of et743 for treating cancer |
| MY130271A (en) | 1999-05-14 | 2007-06-29 | Pharma Mar Sa | Hemisynthetic method and new compounds |
| KR100886496B1 (ko) | 2000-04-12 | 2009-03-05 | 파르마 마르, 에스.에이. | 항종양성 엑티나시딘 유도체 |
| US7247892B2 (en) | 2000-04-24 | 2007-07-24 | Taylor Geoff W | Imaging array utilizing thyristor-based pixel elements |
| MXPA02011319A (es) | 2000-05-15 | 2003-06-06 | Pharma Mar Sa | Analogos antitumorales de ecteinascidina 743. |
| US7420051B2 (en) | 2000-05-15 | 2008-09-02 | Pharma Mar, S.A. | Synthetic process for the manufacture of an ecteinaschidin compound |
| US20020137663A1 (en) | 2000-08-11 | 2002-09-26 | Forman Barry M. | The anti-neoplastic agent ET-743 inhibits trans activation by SXR |
| WO2002036135A2 (en) | 2000-11-06 | 2002-05-10 | Pharma Mar, S.A. | Compositions for antitumour treatment containing ecteinascidin 743 |
| WO2002064843A1 (en) | 2001-02-09 | 2002-08-22 | The Regents Of The University Of California | Ecteinascidin family compounds: compositions and methods |
| AU2002242561A1 (en) | 2001-03-30 | 2002-10-15 | Shire Biochem Inc. | Methods of treating cancer using cyplastin combined with a dioxolane nucleoside such as troxacitabine |
| GB0121285D0 (en) | 2001-09-03 | 2001-10-24 | Cancer Res Ventures Ltd | Anti-cancer combinations |
| PL368458A1 (en) | 2001-10-19 | 2005-03-21 | Pharmamar S.A. | Improved use of antitumoral compound in cancer therapy |
| US20040019027A1 (en) | 2002-04-12 | 2004-01-29 | Barry Forman | Method of treating cerebrotendinous xanthomatosis |
| GB0312407D0 (en) | 2003-05-29 | 2003-07-02 | Pharma Mar Sau | Treatment |
| GB0324201D0 (en) | 2003-10-15 | 2003-11-19 | Pharma Mar Sau | Improved antitumoral combinations |
| JP2007511499A (ja) | 2003-11-13 | 2007-05-10 | ファーマ・マール・エス・アー・ウー | コンビネーション |
| GB0326486D0 (en) | 2003-11-14 | 2003-12-17 | Pharma Mar Sau | Combination treatment |
| JP2007511509A (ja) | 2003-11-14 | 2007-05-10 | ファルマ・マール・ソシエダード・アノニマ | Ｅｔ−７４３およびパクリタキセルの使用を含むガンの併用療法 |
| JP2008505862A (ja) | 2004-07-09 | 2008-02-28 | ファルマ、マール、ソシエダード、アノニマ | 予後分子マーカー |
| WO2006035244A2 (en) | 2004-09-29 | 2006-04-06 | Pharma Mar S.A., Sociedad Unipersonal | Ecteinascidin compounds as anti -inflammatory agents |
| RS50822B (sr) | 2004-10-26 | 2010-08-31 | Pharma Mar S.A., Sociedad Unipersonal | Pegilovani lipozomalni doksorubicin u kombinaciji sa ekteinescidinom 743 |
| KR101188691B1 (ko) | 2004-10-29 | 2012-10-09 | 파르마 마르 에스.에이. | 엑티나시딘 및 디사카라이드를 포함하는 제제 |
| JP2009517403A (ja) | 2005-11-25 | 2009-04-30 | ユニバーシティー オブ メディシン アンド デンティストリー オブ ニュージャージー | Ｐａｒｐ−１阻害剤の使用 |
| WO2007134203A2 (en) | 2006-05-12 | 2007-11-22 | Pharma Mar, S.A. | Anticancer treatments with a combination of docetaxel and ecteinascidin |
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2000
- 2000-05-13 MY MYPI20002107A patent/MY164077A/en unknown
- 2000-05-15 ES ES00927584T patent/ES2272279T3/es not_active Expired - Lifetime
- 2000-05-15 DE DE122008000013C patent/DE122008000013I1/de active Pending
- 2000-05-15 DK DK06014005.0T patent/DK1716853T3/da active
- 2000-05-15 UA UA2001128559A patent/UA74782C2/uk unknown
- 2000-05-15 PL PL352931A patent/PL198185B1/pl unknown
- 2000-05-15 CN CNB2005100091622A patent/CN100477993C/zh not_active Expired - Lifetime
- 2000-05-15 IL IL14643400A patent/IL146434A0/xx active IP Right Grant
- 2000-05-15 HU HU0201187A patent/HU229866B1/hu active Protection Beyond IP Right Term
- 2000-05-15 DE DE60036826T patent/DE60036826T2/de not_active Expired - Lifetime
- 2000-05-15 MX MXPA01011562A patent/MXPA01011562A/es active IP Right Grant
- 2000-05-15 AR ARP000102321A patent/AR028476A1/es not_active Application Discontinuation
- 2000-05-15 AT AT06011784T patent/ATE375795T1/de active
- 2000-05-15 SK SK1644-2001A patent/SK287580B6/sk not_active IP Right Cessation
- 2000-05-15 EP EP06011784A patent/EP1702618B1/en not_active Expired - Lifetime
- 2000-05-15 DE DE60030554T patent/DE60030554T8/de active Active
- 2000-05-15 ES ES06011784T patent/ES2294756T3/es not_active Expired - Lifetime
- 2000-05-15 AT AT06014005T patent/ATE500830T1/de active
- 2000-05-15 AU AU45975/00A patent/AU777417B2/en not_active Expired
- 2000-05-15 NZ NZ515423A patent/NZ515423A/en not_active IP Right Cessation
- 2000-05-15 JP JP2000617900A patent/JP2002544231A/ja not_active Withdrawn
- 2000-05-15 AT AT00927584T patent/ATE338552T1/de active
- 2000-05-15 KR KR1020017014479A patent/KR20020019914A/ko not_active Ceased
- 2000-05-15 TR TR2001/03819T patent/TR200103819T2/xx unknown
- 2000-05-15 CZ CZ20014081A patent/CZ301482B6/cs not_active IP Right Cessation
- 2000-05-15 BR BR0010531-7A patent/BR0010531A/pt not_active Application Discontinuation
- 2000-05-15 SI SI200030977T patent/SI1702618T1/sl unknown
- 2000-05-15 SI SI200031067T patent/SI1716853T1/sl unknown
- 2000-05-15 CN CN00809976A patent/CN1360503A/zh active Pending
- 2000-05-15 DE DE60045720T patent/DE60045720D1/de not_active Expired - Lifetime
- 2000-05-15 CA CA002373794A patent/CA2373794C/en not_active Expired - Lifetime
- 2000-05-15 PT PT00927584T patent/PT1176964E/pt unknown
- 2000-05-15 PT PT06011784T patent/PT1702618E/pt unknown
- 2000-05-15 SI SI200030905T patent/SI1176964T1/sl unknown
- 2000-05-15 DK DK06011784T patent/DK1702618T3/da active
- 2000-05-15 DK DK00927584T patent/DK1176964T3/da active
- 2000-05-15 EP EP06014005A patent/EP1716853B9/en not_active Expired - Lifetime
- 2000-05-15 WO PCT/GB2000/001857 patent/WO2000069441A1/en not_active Ceased
- 2000-05-15 EP EP00927584A patent/EP1176964B8/en not_active Expired - Lifetime
- 2000-05-15 PT PT06014005T patent/PT1716853E/pt unknown
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2001
- 2001-11-11 IL IL146434A patent/IL146434A/en active Protection Beyond IP Right Term
- 2001-11-12 NO NO20015516A patent/NO324564B1/no not_active IP Right Cessation
- 2001-12-03 BG BG106171A patent/BG65680B1/bg unknown
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2005
- 2005-01-14 AU AU2005200180A patent/AU2005200180B9/en not_active Expired
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2006
- 2006-11-30 CY CY20061101734T patent/CY1105818T1/el unknown
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2007
- 2007-06-28 US US11/769,873 patent/US8119638B2/en not_active Expired - Fee Related
-
2008
- 2008-01-16 CY CY20081100059T patent/CY1107143T1/el unknown
- 2008-02-22 NL NL300337C patent/NL300337I2/nl unknown
- 2008-03-10 LU LU91418C patent/LU91418I2/fr unknown
- 2008-04-07 CY CY200800007C patent/CY2008007I2/el unknown
- 2008-04-16 FR FR08C0013C patent/FR08C0013I2/fr active Active
- 2008-05-16 NO NO2008005C patent/NO2008005I1/no not_active IP Right Cessation
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2011
- 2011-06-08 CY CY20111100545T patent/CY1112753T1/el unknown
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2012
- 2012-05-02 JP JP2012105249A patent/JP5777562B2/ja not_active Expired - Lifetime
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2015
- 2015-01-06 HU HUS1500001C patent/HUS1500001I1/hu unknown