FI970771A0 - Uusia allergisten sairauksien hoidossa käyttökelpoisia substituoituja piperidiinejä - Google Patents

Uusia allergisten sairauksien hoidossa käyttökelpoisia substituoituja piperidiinejä

Info

Publication number
FI970771A0
FI970771A0 FI970771A FI970771A FI970771A0 FI 970771 A0 FI970771 A0 FI 970771A0 FI 970771 A FI970771 A FI 970771A FI 970771 A FI970771 A FI 970771A FI 970771 A0 FI970771 A0 FI 970771A0
Authority
FI
Finland
Prior art keywords
treatment
allergic diseases
useful
new substituted
substituted piperidines
Prior art date
Application number
FI970771A
Other languages
English (en)
Swedish (sv)
Other versions
FI970771A (fi
FI114470B (fi
Inventor
Timothy Paul Burkholder
Larry Don Bratton
Elizabeth Mary Kudlacz
George Daniel Maynard
John Michael Kane
Braulio Santiago
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of FI970771A publication Critical patent/FI970771A/fi
Publication of FI970771A0 publication Critical patent/FI970771A0/fi
Application granted granted Critical
Publication of FI114470B publication Critical patent/FI114470B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FI970771A 1994-08-25 1997-02-24 Uusia allergisten sairauksien hoidossa käyttökelpoisia substituoituja piperidiinejä FI114470B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US29596094A 1994-08-25 1994-08-25
US29596094 1994-08-25
US50191495A 1995-07-13 1995-07-13
US50191495 1995-07-13
PCT/US1995/010640 WO1996006094A1 (en) 1994-08-25 1995-08-17 Novel substituted piperidines useful for the treatment of allergic diseases
US9510640 1995-08-17

Publications (3)

Publication Number Publication Date
FI970771A FI970771A (fi) 1997-02-24
FI970771A0 true FI970771A0 (fi) 1997-02-24
FI114470B FI114470B (fi) 2004-10-29

Family

ID=26969426

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970771A FI114470B (fi) 1994-08-25 1997-02-24 Uusia allergisten sairauksien hoidossa käyttökelpoisia substituoituja piperidiinejä

Country Status (20)

Country Link
US (1) US6329392B1 (fi)
EP (1) EP0777666B1 (fi)
JP (1) JPH10504580A (fi)
KR (1) KR100362620B1 (fi)
CN (1) CN1067385C (fi)
AT (1) ATE177095T1 (fi)
AU (1) AU693936B2 (fi)
CA (1) CA2198084C (fi)
DE (1) DE69508093T2 (fi)
DK (1) DK0777666T3 (fi)
ES (1) ES2132709T3 (fi)
FI (1) FI114470B (fi)
GR (1) GR3030253T3 (fi)
HU (1) HU221434B (fi)
IL (1) IL115040A (fi)
MX (1) MX9701305A (fi)
NO (1) NO313237B1 (fi)
NZ (1) NZ292683A (fi)
TW (1) TW430663B (fi)
WO (1) WO1996006094A1 (fi)

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US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
ES2177827T3 (es) * 1995-12-20 2002-12-16 Aventis Pharma Inc 4-(1h-bencimidazol-2-il)(1,4)diazepanes utiles para el tratamiento de enfermedades alergicas.
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
EP0888338B1 (en) * 1996-02-21 2004-11-17 Aventis Pharmaceuticals Inc. Novel substituted n-methyl-n-(4-(4-(1h-benzimidazol-2-yl) 1,4]diazepan-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
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US5998439A (en) * 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
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Also Published As

Publication number Publication date
AU693936B2 (en) 1998-07-09
EP0777666B1 (en) 1999-03-03
KR970705556A (ko) 1997-10-09
MX9701305A (es) 1998-05-31
WO1996006094A1 (en) 1996-02-29
NO313237B1 (no) 2002-09-02
JPH10504580A (ja) 1998-05-06
IL115040A0 (en) 1995-12-08
DE69508093D1 (de) 1999-04-08
CN1067385C (zh) 2001-06-20
EP0777666A1 (en) 1997-06-11
FI970771A (fi) 1997-02-24
ATE177095T1 (de) 1999-03-15
TW430663B (en) 2001-04-21
IL115040A (en) 2000-02-29
CA2198084A1 (en) 1996-02-29
NO970831D0 (no) 1997-02-24
HUT76644A (en) 1997-10-28
CN1158612A (zh) 1997-09-03
ES2132709T3 (es) 1999-08-16
HU221434B (en) 2002-10-28
DE69508093T2 (de) 1999-07-15
GR3030253T3 (en) 1999-08-31
CA2198084C (en) 2000-03-28
DK0777666T3 (da) 1999-09-27
US6329392B1 (en) 2001-12-11
NO970831L (no) 1997-04-18
NZ292683A (en) 1998-07-28
AU3492895A (en) 1996-03-14
KR100362620B1 (ko) 2003-02-14
FI114470B (fi) 2004-10-29

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