PT920425E - 4-(1h-benzimidazol-2-il-amino)piperidinas substituidas uteis para o tratamento de doencas alergicas - Google Patents
4-(1h-benzimidazol-2-il-amino)piperidinas substituidas uteis para o tratamento de doencas alergicasInfo
- Publication number
- PT920425E PT920425E PT96941334T PT96941334T PT920425E PT 920425 E PT920425 E PT 920425E PT 96941334 T PT96941334 T PT 96941334T PT 96941334 T PT96941334 T PT 96941334T PT 920425 E PT920425 E PT 920425E
- Authority
- PT
- Portugal
- Prior art keywords
- treatment
- benzimidazol
- amino
- allergic diseases
- substituted piperidines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56041995A | 1995-11-17 | 1995-11-17 | |
| US73450896A | 1996-10-17 | 1996-10-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT920425E true PT920425E (pt) | 2003-07-31 |
Family
ID=27072328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT96941334T PT920425E (pt) | 1995-11-17 | 1996-11-07 | 4-(1h-benzimidazol-2-il-amino)piperidinas substituidas uteis para o tratamento de doencas alergicas |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0920425B1 (pt) |
| JP (1) | JPH11513991A (pt) |
| KR (1) | KR19990067622A (pt) |
| CN (1) | CN1098264C (pt) |
| AT (1) | ATE232858T1 (pt) |
| AU (1) | AU703701B2 (pt) |
| CA (1) | CA2237971C (pt) |
| DE (1) | DE69626321T2 (pt) |
| DK (1) | DK0920425T3 (pt) |
| ES (1) | ES2188801T3 (pt) |
| HK (1) | HK1018065A1 (pt) |
| HU (1) | HUP9900927A3 (pt) |
| IL (1) | IL124396A (pt) |
| MX (1) | MX9803815A (pt) |
| NO (1) | NO982238L (pt) |
| NZ (1) | NZ323543A (pt) |
| PT (1) | PT920425E (pt) |
| SI (1) | SI0920425T1 (pt) |
| TW (1) | TW394771B (pt) |
| WO (1) | WO1997019074A1 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6194406B1 (en) | 1995-12-20 | 2001-02-27 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease |
| US6423704B2 (en) | 1995-12-20 | 2002-07-23 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
| US5932571A (en) * | 1996-02-21 | 1999-08-03 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases |
| ES2169881T3 (es) * | 1996-12-19 | 2002-07-16 | Aventis Pharma Inc | Nuevos derivados de amida de pirrolidina sustituidos con heterociclo. |
| US5861417A (en) * | 1996-12-19 | 1999-01-19 | Hoechst Marion Roussel, Inc. | Heterocyclic substituted pyrrolidine amide derivatives |
| HUP0001823A3 (en) * | 1997-03-26 | 2002-04-29 | Sepracor Inc | Chemically and thermally stable norastemizole formulations |
| US6713627B2 (en) | 1998-03-13 | 2004-03-30 | Aventis Pharmaceuticals Inc. | Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol |
| PE20020507A1 (es) * | 2000-10-17 | 2002-06-25 | Schering Corp | Compuestos no-imidazoles como antagonistas del receptor histamina h3 |
| AR040406A1 (es) * | 2002-04-18 | 2005-04-06 | Schering Corp | Antagonistas de histamina h3 de benzimidazolona |
| NZ551077A (en) | 2004-05-07 | 2009-05-31 | Janssen Pharmaceutica Nv | Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| MXPA06012929A (es) | 2004-05-07 | 2007-01-26 | Janssen Pharmaceutica Nv | Derivados de adamantil pirrolidin-2-ona como inhibidores de 11-beta hidroxiesteroide deshidrogenasa. |
| CN101039908B (zh) | 2004-08-30 | 2010-06-23 | 詹森药业有限公司 | 作为11-β羟甾类脱氢酶抑制剂的三环内酰胺衍生物 |
| DE602005017159D1 (de) | 2004-08-30 | 2009-11-26 | Janssen Pharmaceutica Nv | Oxysteroid-dehydrogenase-inhibitoren |
| EA012263B1 (ru) | 2004-08-30 | 2009-08-28 | Янссен Фармацевтика Н.В. | Производные n-2-адамантанил-2-феноксиацетамида в качестве ингибиторов 11-бета-гидроксистероид-дегидрогеназы |
| CN101641099A (zh) | 2007-01-24 | 2010-02-03 | 葛兰素集团有限公司 | 包含3,5-二氨基-6-(2,3-二氯苯基)-1,2,4-三嗪或r(-)-2,4-二氨基-5-(2,3-二氯苯基)-6-氟甲基嘧啶和nk1的药物组合物 |
| WO2020113094A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| JP2023505254A (ja) * | 2019-12-06 | 2023-02-08 | セルジーン コーポレーション | ２－（４－クロロフェニル）－ｎ－（（２－（２，６－ジオキソピペリジン－３－イル）－１－オキソイソインドリン－５－イル）メチル）－２，２－ジフルオロアセトアミドを製造するための方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2676055B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| FR2719311B1 (fr) * | 1994-03-18 | 1998-06-26 | Sanofi Sa | Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic. |
| DE69508093T2 (de) * | 1994-08-25 | 1999-07-15 | Merrell Pharma Inc | Substituierte piperidine für die behandlung von allergischen krankheiten |
| ATE205102T1 (de) * | 1994-09-23 | 2001-09-15 | Tranas Rostfria Ab | Ein zusammenbau zum praktizieren des gehens |
| EP0714891A1 (en) * | 1994-11-22 | 1996-06-05 | Eli Lilly And Company | Heterocyclic tachykinin receptor antagonists |
-
1996
- 1996-11-07 ES ES96941334T patent/ES2188801T3/es not_active Expired - Lifetime
- 1996-11-07 EP EP96941334A patent/EP0920425B1/en not_active Expired - Lifetime
- 1996-11-07 AU AU10508/97A patent/AU703701B2/en not_active Ceased
- 1996-11-07 CA CA002237971A patent/CA2237971C/en not_active Expired - Fee Related
- 1996-11-07 DE DE69626321T patent/DE69626321T2/de not_active Expired - Fee Related
- 1996-11-07 SI SI9630597T patent/SI0920425T1/xx unknown
- 1996-11-07 DK DK96941334T patent/DK0920425T3/da active
- 1996-11-07 JP JP9519767A patent/JPH11513991A/ja not_active Abandoned
- 1996-11-07 AT AT96941334T patent/ATE232858T1/de not_active IP Right Cessation
- 1996-11-07 KR KR1019980703649A patent/KR19990067622A/ko active IP Right Grant
- 1996-11-07 IL IL12439696A patent/IL124396A/xx not_active IP Right Cessation
- 1996-11-07 NZ NZ323543A patent/NZ323543A/xx unknown
- 1996-11-07 WO PCT/US1996/018001 patent/WO1997019074A1/en not_active Application Discontinuation
- 1996-11-07 PT PT96941334T patent/PT920425E/pt unknown
- 1996-11-07 HU HU9900927A patent/HUP9900927A3/hu unknown
- 1996-11-07 CN CN96198360A patent/CN1098264C/zh not_active Expired - Fee Related
- 1996-12-20 TW TW085115760A patent/TW394771B/zh not_active IP Right Cessation
-
1998
- 1998-05-13 MX MX9803815A patent/MX9803815A/es unknown
- 1998-05-15 NO NO982238A patent/NO982238L/no not_active Application Discontinuation
-
1999
- 1999-07-20 HK HK99103106A patent/HK1018065A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO982238D0 (no) | 1998-05-15 |
| AU703701B2 (en) | 1999-04-01 |
| CA2237971A1 (en) | 1997-05-29 |
| CN1098264C (zh) | 2003-01-08 |
| MX9803815A (es) | 1998-09-30 |
| KR19990067622A (ko) | 1999-08-25 |
| HUP9900927A3 (en) | 2002-02-28 |
| HK1018065A1 (en) | 1999-12-10 |
| CN1202894A (zh) | 1998-12-23 |
| CA2237971C (en) | 2002-01-22 |
| DK0920425T3 (da) | 2003-05-26 |
| AU1050897A (en) | 1997-06-11 |
| ATE232858T1 (de) | 2003-03-15 |
| JPH11513991A (ja) | 1999-11-30 |
| IL124396A0 (en) | 1998-12-06 |
| ES2188801T3 (es) | 2003-07-01 |
| DE69626321D1 (de) | 2003-03-27 |
| EP0920425B1 (en) | 2003-02-19 |
| EP0920425A1 (en) | 1999-06-09 |
| NZ323543A (en) | 1999-06-29 |
| DE69626321T2 (de) | 2003-08-14 |
| SI0920425T1 (en) | 2003-08-31 |
| TW394771B (en) | 2000-06-21 |
| IL124396A (en) | 2001-03-19 |
| HUP9900927A2 (hu) | 2000-03-28 |
| WO1997019074A1 (en) | 1997-05-29 |
| NO982238L (no) | 1998-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW430663B (en) | Novel substituted piperidines useful for the treatment of allergic diseases | |
| PT920425E (pt) | 4-(1h-benzimidazol-2-il-amino)piperidinas substituidas uteis para o tratamento de doencas alergicas | |
| MX9804991A (es) | 4-(1h-benzimidazol-2-il)(1,4) diazepanes sustituidos novedosos utiles para el tratamiento de enfermedades alergicas. | |
| PT882038E (pt) | N-metil-n-(4-(piperidin-1-il)-2-(aril)butil)benzamidas substituidas vantajosas para o tratamento de doencas alergicas | |
| CA2246994A1 (en) | Novel substituted n-methyl-n-(4-(4-(1h-benzimidazol-2-yl)[1,4]diazepan-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases | |
| CA2247105A1 (en) | Novel substituted n-methyl-n-(4-(4-(1h-benzimidazol-2-yl-amino)piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic di seases |