HK1018065A1 - Substituted 4-(1h-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases - Google Patents
Substituted 4-(1h-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseasesInfo
- Publication number
- HK1018065A1 HK1018065A1 HK99103106A HK99103106A HK1018065A1 HK 1018065 A1 HK1018065 A1 HK 1018065A1 HK 99103106 A HK99103106 A HK 99103106A HK 99103106 A HK99103106 A HK 99103106A HK 1018065 A1 HK1018065 A1 HK 1018065A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- treatment
- useful
- benzimidazol
- amino
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56041995A | 1995-11-17 | 1995-11-17 | |
| US73450896A | 1996-10-17 | 1996-10-17 | |
| PCT/US1996/018001 WO1997019074A1 (en) | 1995-11-17 | 1996-11-07 | Substituted 4-(1h-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1018065A1 true HK1018065A1 (en) | 1999-12-10 |
Family
ID=27072328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK99103106A HK1018065A1 (en) | 1995-11-17 | 1999-07-20 | Substituted 4-(1h-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0920425B1 (pt) |
| JP (1) | JPH11513991A (pt) |
| KR (1) | KR19990067622A (pt) |
| CN (1) | CN1098264C (pt) |
| AT (1) | ATE232858T1 (pt) |
| AU (1) | AU703701B2 (pt) |
| CA (1) | CA2237971C (pt) |
| DE (1) | DE69626321T2 (pt) |
| DK (1) | DK0920425T3 (pt) |
| ES (1) | ES2188801T3 (pt) |
| HK (1) | HK1018065A1 (pt) |
| HU (1) | HUP9900927A3 (pt) |
| IL (1) | IL124396A (pt) |
| MX (1) | MX9803815A (pt) |
| NO (1) | NO982238L (pt) |
| NZ (1) | NZ323543A (pt) |
| PT (1) | PT920425E (pt) |
| SI (1) | SI0920425T1 (pt) |
| TW (1) | TW394771B (pt) |
| WO (1) | WO1997019074A1 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6423704B2 (en) | 1995-12-20 | 2002-07-23 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
| US6194406B1 (en) | 1995-12-20 | 2001-02-27 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease |
| US5932571A (en) * | 1996-02-21 | 1999-08-03 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases |
| JP4195512B2 (ja) * | 1996-12-19 | 2008-12-10 | アベンティス・ファーマスーティカルズ・インコーポレイテッド | 新規な複素環置換ピロリジンアミド誘導体 |
| US5861417A (en) * | 1996-12-19 | 1999-01-19 | Hoechst Marion Roussel, Inc. | Heterocyclic substituted pyrrolidine amide derivatives |
| NZ527201A (en) * | 1997-03-26 | 2004-12-24 | Sepracor Inc | Stable norastemizole formulations comprising coated norastemizole particles |
| US6713627B2 (en) | 1998-03-13 | 2004-03-30 | Aventis Pharmaceuticals Inc. | Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol |
| PE20020507A1 (es) * | 2000-10-17 | 2002-06-25 | Schering Corp | Compuestos no-imidazoles como antagonistas del receptor histamina h3 |
| AU2003223631B2 (en) * | 2002-04-18 | 2006-07-20 | Schering Corporation | 1-(4-Piperidinyl) benzimidazolones as histamine H3 antagonists |
| DE602005007344D1 (de) | 2004-05-07 | 2008-07-17 | Janssen Pharmaceutica Nv | Adamantyl pyrrolidin-2-on-derivate als 11-beta hydroxysteroid dehydrogenas inhibitoren |
| US9012494B2 (en) | 2004-05-07 | 2015-04-21 | Janssen Pharmaceutica N.V. | Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| MX2007002449A (es) | 2004-08-30 | 2007-10-10 | Janssen Pharmaceutica Nv | Derivados de n-2 adamantanil-2-fenoxi-acetamida como inhibidores de deshidrogenasa 11-beta hidroxiesteroide. |
| DE602005017159D1 (de) | 2004-08-30 | 2009-11-26 | Janssen Pharmaceutica Nv | Oxysteroid-dehydrogenase-inhibitoren |
| ES2334246T3 (es) | 2004-08-30 | 2010-03-08 | Janssen Pharmaceutica Nv | Derivados triciclos de adamantilamida como inhibidores de la 11-beta-hidroxiesteroide-deshidrogenasa. |
| EP2117538A1 (en) | 2007-01-24 | 2009-11-18 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-) |
| EP3886854A4 (en) | 2018-11-30 | 2022-07-06 | Nuvation Bio Inc. | PYRROLE AND PYRAZOLE COMPOUNDS AND METHODS OF USE THERE |
| JP2023505254A (ja) * | 2019-12-06 | 2023-02-08 | セルジーン コーポレーション | ２－（４－クロロフェニル）－ｎ－（（２－（２，６－ジオキソピペリジン－３－イル）－１－オキソイソインドリン－５－イル）メチル）－２，２－ジフルオロアセトアミドを製造するための方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2676055B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| FR2719311B1 (fr) * | 1994-03-18 | 1998-06-26 | Sanofi Sa | Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic. |
| HU221434B (en) * | 1994-08-25 | 2002-10-28 | Merrell Pharma Inc | Substituted piperidines, pharmaceutical compositions containing them and their use |
| EP0783349B1 (en) * | 1994-09-23 | 2001-09-05 | Tranas Rostfria Ab | An arrangement for practising walking |
| EP0714891A1 (en) * | 1994-11-22 | 1996-06-05 | Eli Lilly And Company | Heterocyclic tachykinin receptor antagonists |
-
1996
- 1996-11-07 PT PT96941334T patent/PT920425E/pt unknown
- 1996-11-07 JP JP9519767A patent/JPH11513991A/ja not_active Abandoned
- 1996-11-07 SI SI9630597T patent/SI0920425T1/xx unknown
- 1996-11-07 ES ES96941334T patent/ES2188801T3/es not_active Expired - Lifetime
- 1996-11-07 DK DK96941334T patent/DK0920425T3/da active
- 1996-11-07 CN CN96198360A patent/CN1098264C/zh not_active Expired - Fee Related
- 1996-11-07 CA CA002237971A patent/CA2237971C/en not_active Expired - Fee Related
- 1996-11-07 KR KR1019980703649A patent/KR19990067622A/ko active IP Right Grant
- 1996-11-07 NZ NZ323543A patent/NZ323543A/xx unknown
- 1996-11-07 AT AT96941334T patent/ATE232858T1/de not_active IP Right Cessation
- 1996-11-07 AU AU10508/97A patent/AU703701B2/en not_active Ceased
- 1996-11-07 EP EP96941334A patent/EP0920425B1/en not_active Expired - Lifetime
- 1996-11-07 IL IL12439696A patent/IL124396A/xx not_active IP Right Cessation
- 1996-11-07 HU HU9900927A patent/HUP9900927A3/hu unknown
- 1996-11-07 DE DE69626321T patent/DE69626321T2/de not_active Expired - Fee Related
- 1996-11-07 WO PCT/US1996/018001 patent/WO1997019074A1/en not_active Application Discontinuation
- 1996-12-20 TW TW085115760A patent/TW394771B/zh not_active IP Right Cessation
-
1998
- 1998-05-13 MX MX9803815A patent/MX9803815A/es unknown
- 1998-05-15 NO NO982238A patent/NO982238L/no not_active Application Discontinuation
-
1999
- 1999-07-20 HK HK99103106A patent/HK1018065A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0920425B1 (en) | 2003-02-19 |
| CN1098264C (zh) | 2003-01-08 |
| NO982238L (no) | 1998-07-01 |
| CN1202894A (zh) | 1998-12-23 |
| IL124396A0 (en) | 1998-12-06 |
| DK0920425T3 (da) | 2003-05-26 |
| JPH11513991A (ja) | 1999-11-30 |
| AU1050897A (en) | 1997-06-11 |
| PT920425E (pt) | 2003-07-31 |
| HUP9900927A2 (hu) | 2000-03-28 |
| TW394771B (en) | 2000-06-21 |
| ATE232858T1 (de) | 2003-03-15 |
| ES2188801T3 (es) | 2003-07-01 |
| CA2237971A1 (en) | 1997-05-29 |
| NZ323543A (en) | 1999-06-29 |
| AU703701B2 (en) | 1999-04-01 |
| HUP9900927A3 (en) | 2002-02-28 |
| EP0920425A1 (en) | 1999-06-09 |
| IL124396A (en) | 2001-03-19 |
| MX9803815A (es) | 1998-09-30 |
| CA2237971C (en) | 2002-01-22 |
| SI0920425T1 (en) | 2003-08-31 |
| NO982238D0 (no) | 1998-05-15 |
| KR19990067622A (ko) | 1999-08-25 |
| DE69626321D1 (de) | 2003-03-27 |
| WO1997019074A1 (en) | 1997-05-29 |
| DE69626321T2 (de) | 2003-08-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW430663B (en) | Novel substituted piperidines useful for the treatment of allergic diseases | |
| HK1018065A1 (en) | Substituted 4-(1h-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases | |
| MX9804991A (es) | 4-(1h-benzimidazol-2-il)(1,4) diazepanes sustituidos novedosos utiles para el tratamiento de enfermedades alergicas. | |
| IL125577A0 (en) | Novel substituted n-methyl-n-(4-(piperidin-1-yl)-2-(aryl)butyl) benzamides useful for the treatment of allergic diseases | |
| CA2246994A1 (en) | Novel substituted n-methyl-n-(4-(4-(1h-benzimidazol-2-yl)[1,4]diazepan-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases | |
| CA2247105A1 (en) | Novel substituted n-methyl-n-(4-(4-(1h-benzimidazol-2-yl-amino)piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic di seases |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PF | Patent in force | ||
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20061107 |