ES2053401B1
(es)
*
|
1992-01-13 |
1995-03-01 |
Smithkline Beecham Corp |
Compuestos de imidazol y procedimientos para su prepacion.
|
US5916891A
(en)
*
|
1992-01-13 |
1999-06-29 |
Smithkline Beecham Corporation |
Pyrimidinyl imidazoles
|
IL110296A
(en)
*
|
1993-07-16 |
1999-12-31 |
Smithkline Beecham Corp |
Imidazole compounds process for their preparation and pharmaceutical compositions containing them
|
US5593992A
(en)
*
|
1993-07-16 |
1997-01-14 |
Smithkline Beecham Corporation |
Compounds
|
US5783664A
(en)
*
|
1993-09-17 |
1998-07-21 |
Smithkline Beecham Corporation |
Cytokine suppressive anit-inflammatory drug binding proteins
|
US5922751A
(en)
*
|
1994-06-24 |
1999-07-13 |
Euro-Celtique, S.A. |
Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
|
ATE252094T1
(de)
*
|
1994-12-13 |
2003-11-15 |
Hoffmann La Roche |
Imidazol derivate mit proteinkinase, insbesondere egf-r tyrosinkinase, inhibierender wirkung
|
NZ302117A
(en)
*
|
1995-01-12 |
1999-10-28 |
Smithkline Beecham Corp |
1-cycloalkyl or cycloalkylalkyl 4,5-trisubstituted imidazole derivatives and medicaments
|
US5700826A
(en)
*
|
1995-06-07 |
1997-12-23 |
Ontogen Corporation |
1,2,4,5-tetra substituted imidazoles as modulators of multi-drug resistance
|
AU6709596A
(en)
|
1995-08-22 |
1997-03-19 |
Japan Tobacco Inc. |
Amide compounds and use of the same
|
US6083949A
(en)
*
|
1995-10-06 |
2000-07-04 |
Merck & Co., Inc. |
Substituted imidazoles having anti-cancer and cytokine inhibitory activity
|
US5717100A
(en)
*
|
1995-10-06 |
1998-02-10 |
Merck & Co., Inc. |
Substituted imidazoles having anti-cancer and cytokine inhibitory activity
|
DE69637948D1
(de)
*
|
1995-10-06 |
2009-07-23 |
Merck & Co Inc |
Substituierte imidazole mit krebsremmender und cytokininhibierender wirkung
|
AU702887B2
(en)
*
|
1995-10-31 |
1999-03-11 |
Merck & Co., Inc. |
Substituted pyridyl pyrroles, compositions containing such compounds and methods of use
|
ZA9610687B
(en)
*
|
1995-12-22 |
1997-09-29 |
Smithkline Beecham Corp |
Novel synthesis.
|
AP9700912A0
(en)
*
|
1996-01-11 |
1997-01-31 |
Smithkline Beecham Corp |
Novel cycloalkyl substituted imidazoles
|
US6046208A
(en)
*
|
1996-01-11 |
2000-04-04 |
Smithkline Beecham Corporation |
Substituted imidazole compounds
|
US5756499A
(en)
*
|
1996-01-11 |
1998-05-26 |
Smithkline Beecham Corporation |
Substituted imidazole compounds
|
US6372741B1
(en)
|
1996-03-08 |
2002-04-16 |
Smithkline Beecham Corporation |
Use of CSAID™ compounds as inhibitors of angiogenesis
|
JP2000506532A
(ja)
*
|
1996-03-13 |
2000-05-30 |
スミスクライン・ビーチャム・コーポレイション |
サイトカイン介在疾患の治療にて有用な新規ピリミジン化合物
|
JP2000507558A
(ja)
*
|
1996-03-25 |
2000-06-20 |
スミスクライン・ビーチャム・コーポレイション |
Cns損傷についての新規な治療
|
WO1997035855A1
(en)
*
|
1996-03-25 |
1997-10-02 |
Smithkline Beecham Corporation |
Novel treatment for cns injuries
|
US6294541B1
(en)
|
1996-06-06 |
2001-09-25 |
Euro-Celtique S.A. |
Purine derivatives having phosphodiesterase IV inhibition activity
|
JP3418624B2
(ja)
*
|
1996-06-10 |
2003-06-23 |
メルク エンド カンパニー インコーポレーテッド |
サイトカイン阻害活性を有する置換イミダゾール類
|
WO1998007425A1
(en)
|
1996-08-21 |
1998-02-26 |
Smithkline Beecham Corporation |
Imidazole compounds, compositions and use
|
US5744473A
(en)
*
|
1996-09-16 |
1998-04-28 |
Euro-Celtique, S.A. |
PDE IV inhibitors: "bis-compounds"
|
CA2271767A1
(en)
|
1996-11-19 |
1998-05-28 |
Nathan B. Mantlo |
Aryl and heteroaryl substituted fused pyrrole antiinflammatory agents
|
WO1998022109A1
(en)
*
|
1996-11-20 |
1998-05-28 |
Merck & Co., Inc. |
Triaryl substituted imidazoles as glucagon antagonists
|
JP2001504489A
(ja)
*
|
1996-11-20 |
2001-04-03 |
メルク エンド カンパニー インコーポレーテッド |
トリアリール置換イミダゾール及び使用方法
|
US5880139A
(en)
*
|
1996-11-20 |
1999-03-09 |
Merck & Co., Inc. |
Triaryl substituted imidazoles as glucagon antagonists
|
EP0948257A4
(en)
*
|
1996-11-20 |
1999-12-29 |
Merck & Co Inc |
TRIARYL-SUBSTITUTED IMIDAZOLES, COMPOSITIONS CONTAINING THE SAME AND METHOD FOR THEIR USE
|
US6410729B1
(en)
|
1996-12-05 |
2002-06-25 |
Amgen Inc. |
Substituted pyrimidine compounds and methods of use
|
US6096753A
(en)
|
1996-12-05 |
2000-08-01 |
Amgen Inc. |
Substituted pyrimidinone and pyridone compounds and methods of use
|
US5929076A
(en)
*
|
1997-01-10 |
1999-07-27 |
Smithkline Beecham Corporation |
Cycloalkyl substituted imidazoles
|
ATE244234T1
(de)
*
|
1997-04-24 |
2003-07-15 |
Ortho Mcneil Pharm Inc |
Substituierte imidazole zur behandlung von entzündlichen krankheiten
|
CA2293436C
(en)
*
|
1997-06-12 |
2010-10-26 |
Rhone-Poulenc Rorer Limited |
Imidazolyl-cyclic acetals as tnf inhibitors
|
US20020156104A1
(en)
|
1997-06-13 |
2002-10-24 |
Jerry L. Adams |
Novel pyrazole and pyrazoline substituted compounds
|
WO1998057966A1
(en)
*
|
1997-06-19 |
1998-12-23 |
Smithkline Beecham Corporation |
Novel aryloxy substituted pyrimidine imidazole compounds
|
CA2295021A1
(en)
*
|
1997-06-30 |
1999-01-28 |
Ortho-Mcneil Pharmaceutical, Inc. |
2-substituted imidazoles useful in the treatment of inflammatory diseases
|
GB9713726D0
(en)
*
|
1997-06-30 |
1997-09-03 |
Ciba Geigy Ag |
Organic compounds
|
US6489325B1
(en)
|
1998-07-01 |
2002-12-03 |
Smithkline Beecham Corporation |
Substituted imidazole compounds
|
US7301021B2
(en)
|
1997-07-02 |
2007-11-27 |
Smithkline Beecham Corporation |
Substituted imidazole compounds
|
WO1999001452A1
(en)
|
1997-07-02 |
1999-01-14 |
Smithkline Beecham Corporation |
Novel cycloalkyl substituted imidazoles
|
TW517055B
(en)
|
1997-07-02 |
2003-01-11 |
Smithkline Beecham Corp |
Novel substituted imidazole compounds
|
US6562832B1
(en)
|
1997-07-02 |
2003-05-13 |
Smithkline Beecham Corporation |
Substituted imidazole compounds
|
US5840721A
(en)
*
|
1997-07-09 |
1998-11-24 |
Ontogen Corporation |
Imidazole derivatives as MDR modulators
|
JP2001518507A
(ja)
|
1997-10-08 |
2001-10-16 |
スミスクライン・ビーチャム・コーポレイション |
新規シクロアルケニル置換化合物
|
US6022884A
(en)
|
1997-11-07 |
2000-02-08 |
Amgen Inc. |
Substituted pyridine compounds and methods of use
|
PT1043317E
(pt)
|
1997-11-19 |
2009-05-11 |
Kowa Co |
Novos derivados de piridazina e fármacos que os contêm como ingrediente activo
|
AU1723099A
(en)
|
1997-12-12 |
1999-07-05 |
Euro-Celtique S.A. |
3-substituted adenines via2-thioxanthines
|
WO1999032121A1
(en)
|
1997-12-19 |
1999-07-01 |
Smithkline Beecham Corporation |
Compounds of heteroaryl substituted imidazole, their pharmaceutical compositions and uses
|
CA2321559A1
(en)
*
|
1998-02-26 |
1999-09-02 |
Ortho-Mcneil Pharmaceutical, Inc. |
Substituted pyrrolobenzimidazoles for treating inflammatory diseases
|
HUP0102058A3
(en)
|
1998-05-22 |
2002-05-28 |
Smithkline Beecham Corp |
Novel 2-alkyl substituted imidazole compounds, process for their preparation, pharmaceutical compositions containing them and their use
|
US6858617B2
(en)
|
1998-05-26 |
2005-02-22 |
Smithkline Beecham Corporation |
Substituted imidazole compounds
|
AU4273099A
(en)
*
|
1998-06-24 |
2000-01-10 |
Medical Research Council |
Polypeptides, polynucleotides and uses thereof
|
AU4395399A
(en)
*
|
1998-07-02 |
2000-01-24 |
Sankyo Company Limited |
Five-membered heteroaryl compounds
|
EP1112070B1
(en)
*
|
1998-08-20 |
2004-05-12 |
Smithkline Beecham Corporation |
Novel substituted triazole compounds
|
CN1215076C
(zh)
|
1998-09-09 |
2005-08-17 |
症变治疗公司 |
新的果糖1,6-二磷酸酶的杂芳族抑制剂
|
DE19842833B4
(de)
|
1998-09-18 |
2005-04-14 |
Merckle Gmbh |
2-Arylalkylthio-imidazole, 2-Arylalkenylthio-imidazole und 2-Arylalkinylthio-imidazole als Entzündungs-Hemmstoffe und Hemmstoffe der Cytokin-Freisetzung
|
DE69914357T2
(de)
|
1998-11-04 |
2004-11-11 |
Smithkline Beecham Corp. |
Pyridin-4-yl oder pyrimidin-4-yl substituierte pyrazine
|
US6319928B1
(en)
|
1998-11-30 |
2001-11-20 |
Euro-Celtique, S.A. |
Purine derivatives having phosphodiesterase IV inhibition activity
|
US6239279B1
(en)
*
|
1998-12-16 |
2001-05-29 |
Smithkline Beecham Corporation |
Synthesis for 4-aryl-5-pyrimidine imidazole substituted derivatives
|
JP2002534385A
(ja)
|
1999-01-08 |
2002-10-15 |
スミスクライン・ビーチャム・コーポレイション |
新規化合物
|
UA73492C2
(en)
*
|
1999-01-19 |
2005-08-15 |
|
Aromatic heterocyclic compounds as antiinflammatory agents
|
EP1157026A1
(en)
|
1999-02-22 |
2001-11-28 |
Boehringer Ingelheim Pharmaceuticals Inc. |
Polycyclo heterocyclic derivatives as antiinflammatory agents
|
JP2000247959A
(ja)
|
1999-02-26 |
2000-09-12 |
Kowa Co |
ピリダジン−3−オン誘導体及びこれを含有する医薬
|
KR100709497B1
(ko)
|
1999-03-12 |
2007-04-20 |
베링거 인겔하임 파마슈티칼즈, 인코포레이티드 |
소염제로서 유용한 화합물 및 이의 제조방법
|
JP2002539206A
(ja)
|
1999-03-12 |
2002-11-19 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
抗炎症剤としての芳香族複素環化合物
|
HUP0200938A2
(en)
|
1999-04-02 |
2002-10-28 |
Euro Celtique Sa |
Purine derivatives having phosphodiesterase iv inhibition activity and medicaments containing them
|
AU4315100A
(en)
*
|
1999-04-28 |
2000-11-17 |
Sankyo Company Limited |
Preventive or inhibitory agents for hepatopathy
|
BR0010560A
(pt)
|
1999-05-14 |
2002-06-04 |
Ortho Mcneil Pharm Inc |
3-piridil-4-arilpirrois substituìdos e métodos terapêuticos e profiláticos relacionados
|
DE60024830T2
(de)
*
|
1999-07-09 |
2006-06-14 |
Boehringer Ingelheim Pharma |
Verfahren zur herstellung heteroarylsubstituierter ureaverbindungen
|
AU784484B2
(en)
|
1999-11-10 |
2006-04-13 |
Ortho-Mcneil Pharmaceutical, Inc. |
Substituted 2-aryl-3(heteroaryl)-imidazo(1,2-a) pyrimidines, and related pharmaceutical compositions and methods
|
US6808902B1
(en)
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
WO2001038312A1
(en)
|
1999-11-23 |
2001-05-31 |
Smithkline Beecham Corporation |
3,4-DIHYDRO-(1H)QUINAZOLIN-2-ONE COMPOUNDS AS CSBP/p38 KINASE INHIBITORS
|
WO2001038313A1
(en)
|
1999-11-23 |
2001-05-31 |
Smithkline Beecham Corporation |
3,4-DIHYDRO-(1H)QUINAZOLIN-2-ONE COMPOUNDS AS CSBP/p39 kINASE INHIBITORS
|
US6759410B1
(en)
*
|
1999-11-23 |
2004-07-06 |
Smithline Beecham Corporation |
3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
|
JP2003514900A
(ja)
|
1999-11-23 |
2003-04-22 |
スミスクライン・ビーチャム・コーポレイション |
CSBP/p38キナーゼ阻害剤としての3,4−ジヒドロ−(1H)−キナゾリン−2−オン化合物
|
US6525046B1
(en)
|
2000-01-18 |
2003-02-25 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Aromatic heterocyclic compounds as antiinflammatory agents
|
US6608052B2
(en)
|
2000-02-16 |
2003-08-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Compounds useful as anti-inflammatory agents
|
AR029803A1
(es)
*
|
2000-02-21 |
2003-07-16 |
Smithkline Beecham Plc |
Imidazoles sustituidos con piridilo y composiciones farmaceuticas que las comprenden
|
US7235551B2
(en)
|
2000-03-02 |
2007-06-26 |
Smithkline Beecham Corporation |
1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
|
GB0007405D0
(en)
*
|
2000-03-27 |
2000-05-17 |
Smithkline Beecham Corp |
Compounds
|
AU2001244618A1
(en)
*
|
2000-03-30 |
2001-10-15 |
Takeda Chemical Industries Ltd. |
Substituted 1,3-thiazole compounds, their production and use
|
US7563774B2
(en)
|
2000-06-29 |
2009-07-21 |
Metabasis Therapeutics, Inc. |
Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes
|
US6664256B1
(en)
|
2000-07-10 |
2003-12-16 |
Kowa Co., Ltd. |
Phenylpyridazine compounds and medicines containing the same
|
CA2426337A1
(en)
|
2000-10-18 |
2002-04-25 |
Ortho-Mcneil Pharmaceutical, Inc. |
Substituted imidazoles useful in the treatment of inflammatory diseases
|
NZ524806A
(en)
|
2000-10-23 |
2006-03-31 |
Smithkline Beecham Corp |
Tri-substituted 8H-pyrido[2,3-d]pyrimidin-7-one compounds
|
WO2002051442A1
(fr)
*
|
2000-12-26 |
2002-07-04 |
Takeda Chemical Industries, Ltd. |
Co-prescriptions
|
WO2002057265A1
(fr)
|
2001-01-22 |
2002-07-25 |
Sankyo Company, Limited |
Composes substitues avec des groupes amines bicycliques
|
DE10107683A1
(de)
*
|
2001-02-19 |
2002-08-29 |
Merckle Gmbh Chem Pharm Fabrik |
2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
|
US6790846B2
(en)
|
2001-05-24 |
2004-09-14 |
The Procter & Gamble Company |
Isoxazolone compounds useful in treating diseases associated with unwanted cytokine activity
|
ATE464068T1
(de)
|
2001-06-26 |
2010-04-15 |
Amgen Fremont Inc |
Antikörper gegen opgl
|
WO2003049742A1
(en)
*
|
2001-12-11 |
2003-06-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Method for administering birb 796 bs
|
ATE386030T1
(de)
*
|
2002-02-25 |
2008-03-15 |
Boehringer Ingelheim Pharma |
1,4-disubstituierte benzokondensierte cycloalkyl- harnstoffverbindungen zur behandlung von zytokinvermittelten erkrankungen
|
JP4253256B2
(ja)
|
2002-03-27 |
2009-04-08 |
日本シグマックス株式会社 |
治療装置
|
AR039241A1
(es)
|
2002-04-04 |
2005-02-16 |
Biogen Inc |
Heteroarilos trisustituidos y metodos para su produccion y uso de los mismos
|
EP1707205A2
(en)
|
2002-07-09 |
2006-10-04 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Pharmaceutical compositions of anticholinergics and p38 kinase inhibitors in the treatment of respiratory diseases
|
AU2003256297A1
(en)
*
|
2002-08-09 |
2004-02-25 |
Eli Lilly And Company |
Benzimidazoles and benzothiazoles as inhibitors of map kinase
|
US7884120B2
(en)
|
2002-08-19 |
2011-02-08 |
Lorus Therapeutics Inc. |
2,4,5-trisubstituted imidazoles and their use as anti-microbial agents
|
DE10238045A1
(de)
|
2002-08-20 |
2004-03-04 |
Merckle Gmbh Chem.-Pharm. Fabrik |
2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
|
UA80295C2
(en)
|
2002-09-06 |
2007-09-10 |
Biogen Inc |
Pyrazolopyridines and using the same
|
EP1578782A4
(en)
|
2002-12-30 |
2007-09-12 |
Amgen Inc |
COSTIMULATING FACTORIAL THERAPY
|
WO2004063192A1
(en)
*
|
2003-01-10 |
2004-07-29 |
Pharmacopeia Drug Discovery, Inc. |
Imidazolyl pyrimidine derivatives useful as il-8 receptor modulators
|
CL2004000234A1
(es)
*
|
2003-02-12 |
2005-04-15 |
Biogen Idec Inc |
Compuestos derivados 3-(piridin-2-il)-4-heteroaril-pirazol sustituidos, antagonistas de aik5 y/o aik4; composicion farmaceutica y uso del compuesto en el tratamiento de desordenes fibroticos como esclerodermia, lupus nefritico, cicatrizacion de herid
|
CL2004000366A1
(es)
*
|
2003-02-26 |
2005-01-07 |
Pharmacia Corp Sa Organizada B |
USO DE UNA COMBINACION DE UN COMPUESTO DERIVADO DE PIRAZOL INHIBIDOR DE QUINASA p38, Y UN INHIBIDOR DE ACE PARA TRATAR DISFUNCION RENAL, ENFERMEDAD CARDIOVASCULAR Y VASCULAR, RETINOPATIA, NEUROPATIA, EDEMA, DISFUNCION ENDOTELIAL O INSULINOPATIA.
|
US7211577B2
(en)
|
2003-03-18 |
2007-05-01 |
Kowa Co., Ltd. |
Water-soluble phenylpyridazine derivative and medicine containing the same
|
DK1692113T3
(en)
|
2003-11-14 |
2018-01-08 |
Lorus Therapeutics Inc |
ARYLIMIDAZOLES AND USE THEREOF AS ANTICANCES
|
KR20070001922A
(ko)
|
2003-12-12 |
2007-01-04 |
와이어쓰 |
심장혈관질환 치료에 유용한 퀴놀린
|
WO2005063247A1
(en)
*
|
2003-12-22 |
2005-07-14 |
Amgen Inc. |
Aryl sulfonamide compounds and uses related thereto
|
TWI332003B
(en)
*
|
2004-01-30 |
2010-10-21 |
Lilly Co Eli |
Kinase inhibitors
|
US20060035893A1
(en)
|
2004-08-07 |
2006-02-16 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
|
US9512125B2
(en)
|
2004-11-19 |
2016-12-06 |
The Regents Of The University Of California |
Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents
|
US20080119498A1
(en)
*
|
2004-12-06 |
2008-05-22 |
Masatomo Kato |
Therapeutic Agent for Pruritus Comprising P38 Map Kinase Inhibitor as the Active Ingredient
|
PE20060777A1
(es)
|
2004-12-24 |
2006-10-06 |
Boehringer Ingelheim Int |
Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
|
CN101080404B
(zh)
|
2004-12-28 |
2011-06-08 |
Aska制药株式会社 |
嘧啶基异噁唑衍生物
|
KR101327323B1
(ko)
*
|
2005-01-14 |
2013-11-11 |
에스케이바이오팜 주식회사 |
옥사졸 하이드록삼산 유도체 및 이들의 용도
|
UY29440A1
(es)
|
2005-03-25 |
2006-10-02 |
Glaxo Group Ltd |
Nuevos compuestos
|
AU2006250809B2
(en)
|
2005-05-25 |
2011-05-12 |
Lorus Therapeutics Inc. |
2-indolyl imidazo(4,5-D)phenanthroline derivatives and their use in the treatment of cancer
|
TW201018662A
(en)
*
|
2005-12-12 |
2010-05-16 |
Astrazeneca Ab |
Alkylsulphonamide quinolines
|
CA2647391C
(en)
|
2006-04-04 |
2015-12-29 |
The Regents Of The University Of California |
Kinase antagonists
|
EP2044957A4
(en)
|
2006-06-28 |
2011-01-05 |
Aska Pharm Co Ltd |
TREATMENT AGENT FOR INFLAMMATORY BOWEL DISEASE
|
JP5244591B2
(ja)
|
2006-06-28 |
2013-07-24 |
あすか製薬株式会社 |
ピリジルイソオキサゾール誘導体
|
CN101610754A
(zh)
|
2007-02-16 |
2009-12-23 |
Aska制药株式会社 |
含有微粒油性混悬液的药物组合物
|
WO2008133192A1
(ja)
*
|
2007-04-19 |
2008-11-06 |
Takeda Pharmaceutical Company Limited |
縮合イミダゾール化合物およびその用途
|
EP1992344A1
(en)
|
2007-05-18 |
2008-11-19 |
Institut Curie |
P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
|
US20110160232A1
(en)
|
2007-10-04 |
2011-06-30 |
Pingda Ren |
Certain chemical entities and therapeutic uses thereof
|
KR101897881B1
(ko)
|
2008-01-04 |
2018-09-12 |
인텔리카인, 엘엘씨 |
특정 화학 물질, 조성물 및 방법
|
US8193182B2
(en)
*
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
US8637542B2
(en)
|
2008-03-14 |
2014-01-28 |
Intellikine, Inc. |
Kinase inhibitors and methods of use
|
WO2009114874A2
(en)
|
2008-03-14 |
2009-09-17 |
Intellikine, Inc. |
Benzothiazole kinase inhibitors and methods of use
|
CN102124009B
(zh)
|
2008-07-08 |
2014-07-23 |
因特利凯公司 |
激酶抑制剂及其使用方法
|
WO2010006072A2
(en)
|
2008-07-08 |
2010-01-14 |
The Regents Of The University Of California |
Mtor modulators and uses thereof
|
US8703778B2
(en)
|
2008-09-26 |
2014-04-22 |
Intellikine Llc |
Heterocyclic kinase inhibitors
|
WO2010045542A2
(en)
|
2008-10-16 |
2010-04-22 |
The Regents Of The University Of California |
Fused ring heteroaryl kinase inhibitors
|
US8476431B2
(en)
|
2008-11-03 |
2013-07-02 |
Itellikine LLC |
Benzoxazole kinase inhibitors and methods of use
|
US8691866B2
(en)
|
2008-12-10 |
2014-04-08 |
The General Hospital Corporation |
HIF inhibitors and use thereof
|
JP5789252B2
(ja)
|
2009-05-07 |
2015-10-07 |
インテリカイン, エルエルシー |
複素環式化合物およびその使用
|
CA2774040C
(en)
|
2009-09-30 |
2014-09-09 |
Toray Industries, Inc. |
2, 3-dihydro-1h-inden-2-yl urea derivatives and medical uses thereof
|
WO2011047384A2
(en)
|
2009-10-16 |
2011-04-21 |
The Regents Of The University Of California |
Methods of inhibiting ire1
|
EP2571357B1
(en)
|
2010-05-21 |
2016-07-06 |
Infinity Pharmaceuticals, Inc. |
Chemical compounds, compositions and methods for kinase modulation
|
WO2012064973A2
(en)
|
2010-11-10 |
2012-05-18 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
US8809349B2
(en)
|
2011-01-10 |
2014-08-19 |
Infinity Pharmaceuticals, Inc. |
Processes for preparing isoquinolinones and solid forms of isoquinolinones
|
US9295673B2
(en)
|
2011-02-23 |
2016-03-29 |
Intellikine Llc |
Combination of mTOR inhibitors and P13-kinase inhibitors, and uses thereof
|
US20140163075A1
(en)
*
|
2011-06-01 |
2014-06-12 |
Netherland Cancer Institute |
Modulation of the ubiquitin-proteasome system (ups)
|
CN103930422A
(zh)
|
2011-07-19 |
2014-07-16 |
无限药品股份有限公司 |
杂环化合物及其用途
|
JP6027611B2
(ja)
|
2011-07-19 |
2016-11-16 |
インフィニティー ファーマシューティカルズ, インコーポレイテッド |
複素環式化合物及びその使用
|
AU2012302197B2
(en)
|
2011-08-29 |
2016-01-07 |
Infinity Pharmaceuticals Inc. |
Heterocyclic compounds and uses thereof
|
MX370814B
(es)
|
2011-09-02 |
2020-01-08 |
Univ California |
Pirazolo[3,4-d]pirimidinas sustituidas y usos de las mismas.
|
JP2015503505A
(ja)
*
|
2011-12-23 |
2015-02-02 |
ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. |
ヘテロアリールおよびその使用
|
EP2799537B1
(en)
|
2011-12-28 |
2021-09-22 |
Kyoto Prefectural Public University Corporation |
Normalization of culture of corneal endothelial cells
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
US8828998B2
(en)
|
2012-06-25 |
2014-09-09 |
Infinity Pharmaceuticals, Inc. |
Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
|
AU2013323426A1
(en)
|
2012-09-26 |
2015-04-23 |
The Regents Of The University Of California |
Modulation of ire1
|
US9481667B2
(en)
|
2013-03-15 |
2016-11-01 |
Infinity Pharmaceuticals, Inc. |
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
|
US9309247B2
(en)
|
2013-03-20 |
2016-04-12 |
Lorus Therapeutics Inc. |
2-substituted imidazo[4,5-D]phenanthroline derivatives and their use in the treatment of cancer
|
US9475773B2
(en)
|
2013-04-19 |
2016-10-25 |
Astrazeneca Ab |
NK3 receptor antagonist compound (NK3RA) for use in a method for the treatment of polycystic ovary syndrome (PCOS)
|
US9751888B2
(en)
|
2013-10-04 |
2017-09-05 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
WO2015051302A1
(en)
|
2013-10-04 |
2015-04-09 |
Aptose Biosciences Inc. |
Compositions and methods for treating cancers
|
JP6466924B2
(ja)
|
2013-10-04 |
2019-02-06 |
インフィニティー ファーマシューティカルズ, インコーポレイテッド |
複素環式化合物及びその使用
|
CA2928626C
(en)
|
2013-11-14 |
2023-03-14 |
The Doshisha |
Drug for treating corneal endothelium by promoting cell proliferation or inhibiting cell damage
|
DK3119397T3
(da)
|
2014-03-19 |
2022-03-28 |
Infinity Pharmaceuticals Inc |
Heterocykliske forbindelser til anvendelse i behandling af PI3K-gamma-medierede lidelser
|
WO2015160975A2
(en)
|
2014-04-16 |
2015-10-22 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
WO2016054491A1
(en)
|
2014-10-03 |
2016-04-07 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
EP3313420B1
(en)
|
2015-06-25 |
2024-03-13 |
The Children's Medical Center Corporation |
Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance
|
KR20180058741A
(ko)
|
2015-09-14 |
2018-06-01 |
인피니티 파마슈티칼스, 인코포레이티드 |
이소퀴놀리논의 고체형, 그의 제조 방법, 이를 포함하는 조성물 및 이를 사용하는 방법
|
WO2017161001A1
(en)
|
2016-03-15 |
2017-09-21 |
Children's Medical Center Corporation |
Methods and compositions relating to hematopoietic stem cell expansion
|
WO2017161116A1
(en)
|
2016-03-17 |
2017-09-21 |
Infinity Pharmaceuticals, Inc. |
Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
|
US10919914B2
(en)
|
2016-06-08 |
2021-02-16 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
CA3028718A1
(en)
|
2016-06-24 |
2017-12-28 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
FR3060987B1
(fr)
*
|
2016-12-22 |
2020-10-02 |
Oreal |
Procede de coloration des fibres keratiniques mettant en oeuvre au moins un colorant triarylmethane particulier et au moins un colorant fluorescent
|
JP2021501203A
(ja)
|
2017-10-30 |
2021-01-14 |
アプトース バイオサイエンシズ インコーポレイテッド |
がん治療用のアリールイミダゾール
|