AU2001244618A1 - Substituted 1,3-thiazole compounds, their production and use - Google Patents

Substituted 1,3-thiazole compounds, their production and use

Info

Publication number
AU2001244618A1
AU2001244618A1 AU2001244618A AU4461801A AU2001244618A1 AU 2001244618 A1 AU2001244618 A1 AU 2001244618A1 AU 2001244618 A AU2001244618 A AU 2001244618A AU 4461801 A AU4461801 A AU 4461801A AU 2001244618 A1 AU2001244618 A1 AU 2001244618A1
Authority
AU
Australia
Prior art keywords
substituted
production
thiazole compounds
thiazole
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001244618A
Inventor
Hiroyuki Kimura
Seiji Miwatashi
Ken-Ichi Naruo
Shigenori Ohkawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of AU2001244618A1 publication Critical patent/AU2001244618A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
AU2001244618A 2000-03-30 2001-03-29 Substituted 1,3-thiazole compounds, their production and use Abandoned AU2001244618A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2000-097876 2000-03-30
JP2000097876 2000-03-30
JP2001027571 2001-02-02
PCT/JP2001/002629 WO2001074811A2 (en) 2000-03-30 2001-03-29 Substituted 1,3-thiazole compounds, their production and use
JP2001-027571 2002-02-02

Publications (1)

Publication Number Publication Date
AU2001244618A1 true AU2001244618A1 (en) 2001-10-15

Family

ID=26589144

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001244618A Abandoned AU2001244618A1 (en) 2000-03-30 2001-03-29 Substituted 1,3-thiazole compounds, their production and use

Country Status (5)

Country Link
US (1) US7495018B2 (en)
EP (1) EP1268474A2 (en)
AU (1) AU2001244618A1 (en)
CA (1) CA2404384A1 (en)
WO (1) WO2001074811A2 (en)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7199124B2 (en) * 2001-02-02 2007-04-03 Takeda Pharmaceutical Company Limited JNK inhibitor
MY130778A (en) * 2001-02-09 2007-07-31 Vertex Pharma Heterocyclic inhibitiors of erk2 and uses thereof
JP2004530700A (en) * 2001-05-18 2004-10-07 エンダシア，インコーポレイテッド Methods and formulations using A1 adenosine and P2X purine receptor antagonists
US20040033228A1 (en) 2002-08-16 2004-02-19 Hans-Juergen Krause Formulation of human antibodies for treating TNF-alpha associated disorders
MXPA05002082A (en) * 2002-08-23 2005-06-08 Rigel Pharmaceuticals Inc Pyridyl substituted heterocycles useful for treating or preventing hcv infection.
ATE457716T1 (en) 2002-12-30 2010-03-15 Angiotech Int Ag RELEASE OF ACTIVE INGREDIENTS FROM QUICK-GELLING POLYMER COMPOSITION
ES2349532T3 (en) * 2003-02-06 2011-01-04 Bristol-Myers Squibb Company THIAZOLYL-BASED COMPOUNDS USEFUL AS KINASE INHIBITORS.
WO2004099165A2 (en) 2003-05-02 2004-11-18 Rigel Pharmaceuticals, Inc. Heterocyclic compounds and hydro isomers thereof
US20050106230A1 (en) * 2003-11-17 2005-05-19 Young Janel E. Drug-enhanced adhesion prevention
WO2005049065A2 (en) 2003-11-19 2005-06-02 Rigel Pharmaceuticals, Inc. Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections
HUE025659T2 (en) * 2003-12-26 2016-04-28 Kyowa Hakko Kirin Co Ltd Thiazole derivative
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
CA2575466A1 (en) 2004-08-13 2006-02-23 Genentech, Inc. Thiazole based inhibitors of atp-utilizing enzymes
AU2005314133B2 (en) * 2004-12-06 2012-03-08 Medicinova, Inc. Ibudilast for treating neuropathic pain and associated syndromes
US20100130473A1 (en) * 2005-02-25 2010-05-27 Marc Geoffrey Hummersone Compounds
WO2007027230A2 (en) 2005-05-02 2007-03-08 Rigel Pharmaceuticals, Inc. Heterocyclic anti-viral compounds comprising metabolizable moieties and their uses
KR100848205B1 (en) * 2005-06-20 2008-07-24 주식회사 동부하이텍 New substituted 1,3-thiazole derivatives or pharmaceutically acceptable salts thereof having immunosuppression and inflammation inhibitory activity, intermediate compounds or pharmaceutically acceptable salts thereof, a process for the preparation thereof, and pharmaceutical composition comprising the same
US20100280023A1 (en) * 2005-06-23 2010-11-04 Kyowa Hakko Kogyo Co., Ltd. Thiazole derivatives
PT1921077T (en) * 2005-08-02 2017-10-26 Kyowa Hakko Kirin Co Ltd Agent for treating and/or preventing sleep disorder
EA015497B1 (en) * 2005-12-13 2011-08-30 Кадила Хелзкэр Лимитед SULFOXIMINE DERIVATIVES AS p38 MAP KINASE INHIBITORS
WO2007084391A2 (en) * 2006-01-18 2007-07-26 Amgen Inc. Thiazole compounds as protein kinase b ( pkb) inhibitors
AU2007208225B2 (en) * 2006-01-25 2013-05-02 Synta Pharmaceuticals Corp. Thiazole and thiadiazole compounds for inflammation and immune-related uses
WO2008021338A2 (en) 2006-08-15 2008-02-21 Wyeth Tricyclic oxazolidone derivatives useful as pr modulators
TW200815428A (en) 2006-08-15 2008-04-01 Wyeth Corp Oxazolidone derivatives as PR modulators
NZ574222A (en) 2006-08-15 2012-03-30 Novartis Ag 2-(2-Oxoimidazolidin-1-yl)-thiazole-5-carboxamide derivatives and pharmaceutical uses thereof
GB0701426D0 (en) * 2007-01-25 2007-03-07 Univ Sheffield Compounds and their use
EP2131841B1 (en) * 2007-01-30 2012-08-01 Avigen, Inc. Methods for treating acute pain
US20080287402A1 (en) * 2007-05-03 2008-11-20 Johnson Kirk W Use of a glial attenuator to prevent amplified pain responses caused by glial priming
WO2009011871A2 (en) * 2007-07-17 2009-01-22 Amgen Inc. Thiadiazole modulators of pkb
AU2008276521B2 (en) 2007-07-17 2011-11-03 Amgen Inc. Heterocyclic modulators of PKB
NZ587350A (en) 2008-02-20 2012-07-27 Novartis Ag Thiazole derivatives featuring an imidazolidine or triazole derivative as inhibitors of stearoyl-CoA desaturase
US8865732B2 (en) 2008-03-21 2014-10-21 Novartis Ag Heterocyclic compounds and uses thereof
AU2012203026B2 (en) * 2008-03-21 2014-06-12 Novartis Ag Novel heterocyclic compounds and uses thereof
WO2009140517A1 (en) 2008-05-14 2009-11-19 Hydra Biosciences, Inc. Compounds and compositions for treating chemical warfare agent-induced injuries
US8318728B2 (en) 2008-05-14 2012-11-27 Hydra Biosciences, Inc. Compounds and compositions for treating chemical warfare agent-induced injuries
WO2009147178A2 (en) * 2008-06-04 2009-12-10 Nycomed Gmbh Novel medical use of substituted pyridin-2-ylmethylsulphinyl-1h-benzimidazoles
EP2198710A1 (en) 2008-12-19 2010-06-23 Bayer CropScience AG Use of 5-pyridin-4yl-(1,3) thiazoles for combating phytopathogenic fungi
WO2010132838A1 (en) * 2009-05-14 2010-11-18 Hydra Biosciences, Inc. Compounds useful for treating disorders related to trpa1
EP2308866A1 (en) 2009-10-09 2011-04-13 Bayer CropScience AG Phenylpyri(mi)dinylpyrazoles and their use as fungicides
US9242969B2 (en) 2013-03-14 2016-01-26 Novartis Ag Biaryl amide compounds as kinase inhibitors
UY36294A (en) 2014-09-12 2016-04-29 Novartis Ag COMPOUNDS AND COMPOSITIONS AS QUINASA INHIBITORS
WO2017151409A1 (en) 2016-02-29 2017-09-08 University Of Florida Research Foundation, Incorporated Chemotherapeutic methods
CN108495852B (en) * 2016-09-08 2021-06-15 四川科伦博泰生物医药股份有限公司 2-amido thiazole derivatives, preparation method and application thereof
CN109293652B (en) * 2017-07-24 2021-10-22 四川科伦博泰生物医药股份有限公司 Substituted thiazole derivative and application thereof
GB202011996D0 (en) * 2020-07-31 2020-09-16 Adorx Therapeutics Ltd Antagonist compounds
TW202337467A (en) * 2022-01-07 2023-10-01 愛爾蘭商赫瑞森治療學愛爾蘭指定活動公司 Heterocyclic inhibitors of glut9 for treatment of disease
GB2615307A (en) * 2022-01-28 2023-08-09 Adorx Therapeutics Ltd Antagonist compounds

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649146A (en) 1983-01-31 1987-03-10 Fujisawa Pharmaceutical Co., Ltd. Thiazole derivatives and pharmaceutical composition comprising the same
JPS6110580A (en) * 1984-04-17 1986-01-18 Takeda Chem Ind Ltd 5-pyridyl-1,3-thiazole derivative, preparation thereof and pharmaceutical composition containing same
DE3486009T2 (en) * 1983-09-09 1993-04-15 Takeda Chemical Industries Ltd 5-PYRIDYL-1,3-THIAZOL DERIVATIVES, THEIR PRODUCTION AND USE.
DE3669160D1 (en) * 1985-03-27 1990-04-05 Zenyaku Kogyo Kk Thiazolderivate.
JPS61225182A (en) * 1985-03-29 1986-10-06 Zenyaku Kogyo Kk Production of thiazole derivative
US4670450A (en) * 1985-11-13 1987-06-02 Merrell Dow Pharmaceuticals Inc. Cardiotonic thiazolones
DE3703435A1 (en) * 1987-02-05 1988-08-18 Thomae Gmbh Dr K NEW THIAZOLES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
JPH0570446A (en) * 1991-09-13 1993-03-23 Taisho Pharmaceut Co Ltd N-thiazolylsulfonamide derivative
IL104369A0 (en) * 1992-01-13 1993-05-13 Smithkline Beecham Corp Novel compounds and compositions
GB9201692D0 (en) * 1992-01-27 1992-03-11 Smithkline Beecham Intercredit Compounds
EP0727998B1 (en) 1993-11-08 2004-01-21 Smithkline Beecham Corporation Oxazoles for treating cytokine mediated diseases
CA2234066C (en) 1995-10-06 2005-12-13 Merck & Co., Inc. Substituted imidazoles having anti-cancer and cytokine inhibitory activity
JPH1149762A (en) * 1997-08-08 1999-02-23 Japan Tobacco Inc Thiazole compound
WO1999021555A2 (en) 1997-10-27 1999-05-06 Takeda Chemical Industries, Ltd. Adenosine a3 receptor antagonists
WO1999064418A1 (en) * 1998-06-05 1999-12-16 Novartis Ag Aryl pyridinyl thiazoles
KR100449215B1 (en) * 1999-04-23 2004-09-18 다케다 야쿠힌 고교 가부시키가이샤 5-pyridyl-1,3-azole compounds, process for producing the same and use thereof
CA2381215A1 (en) * 1999-08-06 2001-02-15 Takeda Chemical Industries, Ltd. P38map kinase inhibitors

Also Published As

Publication number Publication date
EP1268474A2 (en) 2003-01-02
WO2001074811A3 (en) 2002-02-07
US7495018B2 (en) 2009-02-24
CA2404384A1 (en) 2001-10-11
WO2001074811A2 (en) 2001-10-11
US20040053973A1 (en) 2004-03-18

Similar Documents

Publication Publication Date Title
AU2001244618A1 (en) Substituted 1,3-thiazole compounds, their production and use
AU2001230026A1 (en) 2,4-diaminothiazole derivatives
AU1271201A (en) Azepinoindole derivatives, the production and use thereof
AU2002224927A1 (en) Use of substituted imidazoazines, novel imidazoazines, methods for the production thereof, and agents containing these compounds
AU2001248279A1 (en) New compounds, their preparation and use
GB0105678D0 (en) 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides
AU2002219135A1 (en) Substituted 2-anilino-benzimidazoles and the use thereof as NHE-inhibitors
AU2001240637A1 (en) Novel imidazotriazinones and the use thereof
AU2001279535A1 (en) Bone-regeneration material
AU2001294240A1 (en) 2,2-diphenylbutanamide derivatives and medicines containing the same
AU4122901A (en) Novel 7,8-dihydro-xanthenone-8-carboxylic acid derivative and novel microbe producing the same
AU2000231564A1 (en) Phosphororganic compounds and the use thereof
AU2001248456A1 (en) Novel 1,2,3,4-tetrahydrosioquinoline, their preparation method and their use as fungicides
AU2001262229A1 (en) Cyclipostins, a method for their production and the use of the same
AU2001232089A1 (en) Compound, composition and use
AU2001228624A1 (en) Implements and their manufacture
AU2001252254A1 (en) 2,6-diamino-6-methyl-heptanoic acid and derivatives, process for the preparationthereof and use thereof
AU2001252046A1 (en) New bacteriocin, production and use thereof
AU2002219846A1 (en) Novel use
AU2001239221A1 (en) Novel aminosilyl borylalkanes, their production and use
AU6390001A (en) 6,10-dimethyl-5,9-undecadien-2-ol
AU2001291845A1 (en) Delta1-pyrrolines used as pesticides
AU2001256791A1 (en) 5,6-trans-2-alkylvitamin d derivatives
AU6042601A (en) Compounds and their uses
AU2001232226A1 (en) 1,3,4-oxadiazole derivatives and process for producing the same