FI854536A0 - Foerfarande foer framstaellning av isosilybinfri silibin och silibin innehaollande laekemedel. - Google Patents
Foerfarande foer framstaellning av isosilybinfri silibin och silibin innehaollande laekemedel.Info
- Publication number
- FI854536A0 FI854536A0 FI854536A FI854536A FI854536A0 FI 854536 A0 FI854536 A0 FI 854536A0 FI 854536 A FI854536 A FI 854536A FI 854536 A FI854536 A FI 854536A FI 854536 A0 FI854536 A0 FI 854536A0
- Authority
- FI
- Finland
- Prior art keywords
- silibin
- isosilybinfri
- och
- foerfarande foer
- foer framstaellning
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
- F16L59/00—Thermal insulation in general
- F16L59/04—Arrangements using dry fillers, e.g. using slag wool which is added to the object to be insulated by pouring, spreading, spraying or the like
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI903812A FI85855C (fi) | 1984-11-22 | 1990-07-31 | Foerfarande foer framstaellning av isosilybinfri silibin och silibin innehaollande laekemedel. |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3442641 | 1984-11-22 | ||
DE3442641 | 1984-11-22 | ||
DE19853537656 DE3537656A1 (de) | 1984-11-22 | 1985-10-23 | Verfahren zur herstellung von isosilybinfreiem silibinin und arzneimittel, enthaltend silibinin |
DE3537656 | 1985-10-23 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI854536A0 true FI854536A0 (fi) | 1985-11-18 |
FI854536A FI854536A (fi) | 1986-05-23 |
FI84065B FI84065B (fi) | 1991-06-28 |
FI84065C FI84065C (fi) | 1991-10-10 |
Family
ID=25826741
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI854536A FI84065C (fi) | 1984-11-22 | 1985-11-18 | Foerfarande foer framstaellning av isosilybinfri silibinin. |
Country Status (26)
Country | Link |
---|---|
US (1) | US4871763A (fi) |
JP (1) | JPH0678228B2 (fi) |
AR (1) | AR241268A1 (fi) |
AT (1) | AT391315B (fi) |
BE (1) | BE903694A (fi) |
CA (1) | CA1337125C (fi) |
CH (1) | CH660008A5 (fi) |
CS (1) | CS271321B2 (fi) |
DE (1) | DE3537656A1 (fi) |
DK (3) | DK166541B1 (fi) |
EG (1) | EG17710A (fi) |
ES (2) | ES8609312A1 (fi) |
FI (1) | FI84065C (fi) |
FR (1) | FR2573426B1 (fi) |
GB (1) | GB2167746B (fi) |
HU (1) | HU195504B (fi) |
IE (1) | IE59209B1 (fi) |
IT (1) | IT1207508B (fi) |
LU (1) | LU86164A1 (fi) |
MX (1) | MX172175B (fi) |
NL (1) | NL192204C (fi) |
NO (1) | NO160206C (fi) |
PL (1) | PL146889B1 (fi) |
PT (1) | PT81531B (fi) |
SE (1) | SE457957B (fi) |
YU (1) | YU43690B (fi) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3357383B2 (ja) * | 1991-08-14 | 2002-12-16 | 昌宏 黒田 | 低分子化植物性組成物 |
DE4401902C2 (de) * | 1994-01-24 | 2000-02-03 | Madaus Ag | Verwendung von Flavolignanen als Adjuvans in der Tumortherapie |
FR2719451B1 (fr) * | 1994-05-04 | 1996-07-26 | Apcis Sa | Utilisation de la silybinine dans le gavage des palmipèdes, en vue de l'obtention d'un foie gras de meilleure qualité. |
DE19501266A1 (de) * | 1995-01-18 | 1996-07-25 | Madaus Ag | Verfahren zur Herstellung von Flavano-Lignan-Zubereitungen mit verbesserter Freisetzung und Resorbierbarkeit danach erhältliche Zubereitungen und deren Verwendung zur Herstellung von Arzneimitteln |
US6379714B1 (en) | 1995-04-14 | 2002-04-30 | Pharmaprint, Inc. | Pharmaceutical grade botanical drugs |
DE69824223T2 (de) | 1997-03-19 | 2004-09-30 | Unilever N.V. | Vorrichtung zum Handhaben von Gegenständen |
GB2327607B8 (en) * | 1997-07-31 | 2005-03-30 | Litton Internat Company Ltd | A process for producing a herbal extract composition |
DE10053384A1 (de) * | 2000-10-27 | 2002-05-08 | Bionorica Arzneimittel Gmbh | Pharmazeutische Zubereitung aus Mariendistel und Terpenen |
US6699900B2 (en) * | 2001-04-07 | 2004-03-02 | Jan E. Zielinski | Hydrophilic and lipophilic silibinin pro-forms |
DE10360954B3 (de) * | 2003-12-23 | 2005-08-18 | Esparma Gmbh | Verwendung von Silibinin, dessen Salzen und/oder dessen Prodrugs zusammen mit α-Liponsäure zur Behandlung chronisch obstruktiver Lungenerkrankungen |
BG65997B1 (bg) * | 2005-03-29 | 2010-09-30 | "Софарма" Ад | Метод за получаване на силибинин |
ES2662700T3 (es) * | 2007-11-15 | 2018-04-09 | Madaus Gmbh | Componente de silibinina para el tratamiento de la hepatitis |
ES2593858T3 (es) * | 2009-05-14 | 2016-12-13 | Madaus Gmbh | Método para preparar silibinina amorfa |
WO2011051742A1 (en) | 2009-10-28 | 2011-05-05 | Modutech S.A. | Preparation comprising amino acids and plants and its activity in the alcohol detoxification |
CN103408539B (zh) * | 2013-08-28 | 2016-04-06 | 天津泰阳制药有限公司 | 高纯度水飞蓟宾的生产方法 |
CN109071482A (zh) * | 2016-01-15 | 2018-12-21 | 汉堡大学 | 携有o-鼠李糖基残基的类黄酮型化合物 |
CN117255627A (zh) | 2020-09-29 | 2023-12-19 | 穆尼塞克哈尔·梅达萨尼 | 水飞蓟植物物质中生物活性化合物的提取及应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1767666C3 (de) * | 1968-06-01 | 1986-07-31 | Dr. Madaus & Co, 5000 Koeln | Pharmazeutische Zubereitung gegen Lebererkrankungen |
DE1923082C3 (de) * | 1969-05-06 | 1985-08-22 | Dr. Madaus & Co, 5000 Koeln | Verfahren zur Gewinnung von Polyhydroxyphenylchromanonen (Silymarin I-IV) und Arzneimittel enthaltend das Polyhydroxyphenylchromanon (Silymarin I-IV = Silymarin I-IV-Gruppe)Gemisch |
US3773932A (en) * | 1968-06-01 | 1973-11-20 | Madaus & Co Dr | Method for recovering silymarin comprising polyhydroxyphenyl chromanones |
DE2416302B2 (de) * | 1974-04-04 | 1978-02-02 | Dr. Madaus & Co, 5000 Köln | Dimeres sowie trimeres silybin und deren n-methylglucaminsalz und verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
BE885558A (fr) * | 1980-10-07 | 1981-04-07 | Madaus & Co Dr | Procede pour l'extraction de silymarine a partir des plantes silymarine ainsi obtenue et son utilisation en therapeutique |
DE3225688A1 (de) * | 1982-07-09 | 1984-01-12 | Suschnik Matthias Dr | Verfahren zur gewinnung von silymarin aus silybum marianum |
-
1985
- 1985-10-23 DE DE19853537656 patent/DE3537656A1/de active Granted
- 1985-11-11 GB GB08527809A patent/GB2167746B/en not_active Expired
- 1985-11-12 CH CH4854/85A patent/CH660008A5/de not_active IP Right Cessation
- 1985-11-13 LU LU86164A patent/LU86164A1/de unknown
- 1985-11-14 NL NL8503136A patent/NL192204C/nl not_active IP Right Cessation
- 1985-11-18 FI FI854536A patent/FI84065C/fi not_active IP Right Cessation
- 1985-11-19 AT AT0337285A patent/AT391315B/de not_active IP Right Cessation
- 1985-11-20 SE SE8505488A patent/SE457957B/sv not_active IP Right Cessation
- 1985-11-20 CS CS858379A patent/CS271321B2/cs unknown
- 1985-11-20 YU YU1812/85A patent/YU43690B/xx unknown
- 1985-11-20 CA CA000495805A patent/CA1337125C/en not_active Expired - Fee Related
- 1985-11-21 HU HU854449A patent/HU195504B/hu not_active IP Right Cessation
- 1985-11-21 EG EG741/85A patent/EG17710A/xx active
- 1985-11-21 ES ES549119A patent/ES8609312A1/es not_active Expired
- 1985-11-21 NO NO854657A patent/NO160206C/no unknown
- 1985-11-21 IE IE292785A patent/IE59209B1/en not_active IP Right Cessation
- 1985-11-21 PT PT81531A patent/PT81531B/pt not_active IP Right Cessation
- 1985-11-21 PL PL1985256373A patent/PL146889B1/pl unknown
- 1985-11-21 DK DK537685A patent/DK166541B1/da not_active IP Right Cessation
- 1985-11-21 IT IT8522933A patent/IT1207508B/it active
- 1985-11-22 MX MX009231A patent/MX172175B/es unknown
- 1985-11-22 BE BE2/60851A patent/BE903694A/fr not_active IP Right Cessation
- 1985-11-22 AR AR85302358A patent/AR241268A1/es active
- 1985-11-22 FR FR8517320A patent/FR2573426B1/fr not_active Expired
-
1986
- 1986-04-16 ES ES554022A patent/ES8704482A1/es not_active Expired
-
1988
- 1988-03-18 US US07/171,176 patent/US4871763A/en not_active Expired - Fee Related
-
1991
- 1991-01-29 JP JP3009169A patent/JPH0678228B2/ja not_active Expired - Lifetime
- 1991-11-20 DK DK189491A patent/DK164866C/da not_active IP Right Cessation
-
1992
- 1992-09-17 DK DK199201145A patent/DK172879B1/da active
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed | ||
MM | Patent lapsed |
Owner name: MADAUS AKTIENGESELLSCHAFT |