FI832758A0 - Foerfarande foer framstaellning av metylendifosfonsyraderivat - Google Patents

Foerfarande foer framstaellning av metylendifosfonsyraderivat

Info

Publication number
FI832758A0
FI832758A0 FI832758A FI832758A FI832758A0 FI 832758 A0 FI832758 A0 FI 832758A0 FI 832758 A FI832758 A FI 832758A FI 832758 A FI832758 A FI 832758A FI 832758 A0 FI832758 A0 FI 832758A0
Authority
FI
Finland
Prior art keywords
metylendifosfonsyraderivat
foerfarande foer
foer framstaellning
framstaellning
foerfarande
Prior art date
Application number
FI832758A
Other languages
English (en)
Other versions
FI75830B (fi
FI75830C (fi
FI832758A (fi
Inventor
Jean-Claude Breliere
Xavier Emonds-Alt
Georges Garcia
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of FI832758A0 publication Critical patent/FI832758A0/fi
Publication of FI832758A publication Critical patent/FI832758A/fi
Publication of FI75830B publication Critical patent/FI75830B/fi
Application granted granted Critical
Publication of FI75830C publication Critical patent/FI75830C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • C07F9/6539—Five-membered rings
    • C07F9/6541—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3865—Polyphosphonic acids containing sulfur substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4025—Esters of poly(thio)phosphonic acids
    • C07F9/4043—Esters of poly(thio)phosphonic acids containing sulfur substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
    • C07F9/65068—Five-membered rings having the nitrogen atoms in positions 1 and 3 condensed with carbocyclic rings or carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI832758A 1982-07-29 1983-07-29 Foerfarande foer framstaellning av terapeutiskt anvaendbara metylendifosfonsyraderivat. FI75830C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8213250A FR2531088B1 (fr) 1982-07-29 1982-07-29 Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation
FR8213250 1982-07-29

Publications (4)

Publication Number Publication Date
FI832758A0 true FI832758A0 (fi) 1983-07-29
FI832758A FI832758A (fi) 1984-01-30
FI75830B FI75830B (fi) 1988-04-29
FI75830C FI75830C (fi) 1988-08-08

Family

ID=9276447

Family Applications (1)

Application Number Title Priority Date Filing Date
FI832758A FI75830C (fi) 1982-07-29 1983-07-29 Foerfarande foer framstaellning av terapeutiskt anvaendbara metylendifosfonsyraderivat.

Country Status (35)

Country Link
US (2) US4746654A (fi)
EP (1) EP0100718B1 (fi)
JP (1) JPS5942395A (fi)
KR (1) KR910000726B1 (fi)
AR (2) AR242394A1 (fi)
AT (1) ATE30235T1 (fi)
AU (1) AU566880B2 (fi)
CA (1) CA1267650A (fi)
CS (1) CS252463B2 (fi)
CZ (1) CZ419191A3 (fi)
DD (1) DD213670A5 (fi)
DE (1) DE3374062D1 (fi)
DK (1) DK170342B1 (fi)
DZ (1) DZ562A1 (fi)
EG (1) EG15968A (fi)
ES (1) ES524495A0 (fi)
FI (1) FI75830C (fi)
FR (1) FR2531088B1 (fi)
GR (1) GR79597B (fi)
HU (1) HU190454B (fi)
IE (1) IE56343B1 (fi)
IL (1) IL69347A (fi)
LU (1) LU88723I2 (fi)
MA (1) MA19858A1 (fi)
NL (1) NL960007I2 (fi)
NO (2) NO164712C (fi)
NZ (1) NZ205061A (fi)
OA (1) OA07507A (fi)
PH (1) PH22082A (fi)
PL (2) PL141316B1 (fi)
PT (1) PT77122B (fi)
SG (1) SG18588G (fi)
SU (2) SU1333240A3 (fi)
YU (1) YU45143B (fi)
ZA (1) ZA835578B (fi)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
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US4761406A (en) * 1985-06-06 1988-08-02 The Procter & Gamble Company Regimen for treating osteoporosis
US4902679A (en) * 1985-12-13 1990-02-20 Norwich Eaton Pharmaceuticals, Inc. Methods of treating diseases with certain geminal diphosphonates
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FR2531088B1 (fr) 1987-08-28
CS568883A2 (en) 1987-01-15
KR840005459A (ko) 1984-11-12
NO1998011I1 (no) 1998-03-06
DK170342B1 (da) 1995-08-07
CZ419191A3 (en) 1993-10-13
YU160083A (en) 1986-08-31
PH22082A (en) 1988-05-20
CA1267650A (en) 1990-04-10
ZA835578B (en) 1984-04-25
YU45143B (en) 1992-03-10
OA07507A (fr) 1985-03-31
NL960007I2 (nl) 1997-03-03
LU88723I2 (fr) 1996-08-23
PT77122B (fr) 1986-01-24
ATE30235T1 (de) 1987-10-15
JPH0429676B2 (fi) 1992-05-19
DE3374062D1 (en) 1987-11-19
FI75830B (fi) 1988-04-29
US4876248A (en) 1989-10-24
DD213670A5 (de) 1984-09-19
NO164712C (no) 1990-11-07
FI75830C (fi) 1988-08-08
EG15968A (en) 1989-01-30
ES8403923A1 (es) 1984-04-16
PT77122A (fr) 1983-08-01
EP0100718A1 (fr) 1984-02-15
SU1367859A3 (ru) 1988-01-15
DK336783D0 (da) 1983-07-22
PL142022B1 (en) 1987-09-30
KR910000726B1 (ko) 1991-01-31
NZ205061A (en) 1987-08-31
NO164712B (no) 1990-07-30
DZ562A1 (fr) 2004-09-13
SU1333240A3 (ru) 1987-08-23
AU566880B2 (en) 1987-11-05
FR2531088A1 (fr) 1984-02-03
HU190454B (en) 1986-09-29
FI832758A (fi) 1984-01-30
MA19858A1 (fr) 1984-04-01
GR79597B (fi) 1984-10-31
AU1732483A (en) 1984-02-02
DK336783A (da) 1984-01-30
IL69347A0 (en) 1983-11-30
IE831716L (en) 1984-01-29
PL243229A1 (en) 1984-07-16
US4746654A (en) 1988-05-24
SG18588G (en) 1988-09-30
IE56343B1 (en) 1991-07-03
CS252463B2 (en) 1987-09-17
NL960007I1 (nl) 1996-09-02
IL69347A (en) 1987-02-27
ES524495A0 (es) 1984-04-16
PL141316B1 (en) 1987-07-31
AR242393A1 (es) 1993-03-31
NO832701L (no) 1984-01-30
AR242394A1 (es) 1993-03-31
JPS5942395A (ja) 1984-03-08
EP0100718B1 (fr) 1987-10-14

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