FI822471A0 - Karbostyrilfoereningar, kompositioner innehaollande dem och foerfarande foer framstaellning av dem - Google Patents

Karbostyrilfoereningar, kompositioner innehaollande dem och foerfarande foer framstaellning av dem

Info

Publication number
FI822471A0
FI822471A0 FI822471A FI822471A FI822471A0 FI 822471 A0 FI822471 A0 FI 822471A0 FI 822471 A FI822471 A FI 822471A FI 822471 A FI822471 A FI 822471A FI 822471 A0 FI822471 A0 FI 822471A0
Authority
FI
Finland
Prior art keywords
dem
buckle
filling
foerfarande foer
foer framstaellning
Prior art date
Application number
FI822471A
Other languages
English (en)
Other versions
FI71145C (fi
FI822471L (fi
FI71145B (fi
Inventor
Tominaga Michiaki
Yang Yung-Hsiung
Ogawa Hidenori
Nakagawa Kazuyuki
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP55159016A external-priority patent/JPS5782390A/ja
Priority claimed from JP55179950A external-priority patent/JPS57102888A/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of FI822471L publication Critical patent/FI822471L/fi
Publication of FI822471A0 publication Critical patent/FI822471A0/fi
Application granted granted Critical
Publication of FI71145B publication Critical patent/FI71145B/fi
Publication of FI71145C publication Critical patent/FI71145C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/28—Alcohols; Ethers thereof with halogen atoms or nitro radicals in positions 5, 6 or 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/32—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI822471A 1980-11-11 1982-07-12 Foerfarande foer framstaellning av imidazo/1,2-a/-pyridin-2-yl-karbostyrilderivat vilka aer anvaendbara som hjaertmedicin FI71145C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP55159016A JPS5782390A (en) 1980-11-11 1980-11-11 Carbostyril derivative
JP15901680 1980-11-11
JP55179950A JPS57102888A (en) 1980-12-18 1980-12-18 Carbostyril derivative
JP17995080 1980-12-18
JP8100328 1981-11-11
PCT/JP1981/000328 WO1982001706A1 (en) 1980-11-11 1981-11-11 Carbostyril compounds,composition containing same,and process for their preparation

Publications (4)

Publication Number Publication Date
FI822471L FI822471L (fi) 1982-07-12
FI822471A0 true FI822471A0 (fi) 1982-07-12
FI71145B FI71145B (fi) 1986-08-14
FI71145C FI71145C (fi) 1986-11-24

Family

ID=26485945

Family Applications (1)

Application Number Title Priority Date Filing Date
FI822471A FI71145C (fi) 1980-11-11 1982-07-12 Foerfarande foer framstaellning av imidazo/1,2-a/-pyridin-2-yl-karbostyrilderivat vilka aer anvaendbara som hjaertmedicin

Country Status (19)

Country Link
US (1) US4414390A (fi)
EP (1) EP0052016B1 (fi)
KR (1) KR880001657B1 (fi)
AT (1) AT382376B (fi)
AU (1) AU547586B2 (fi)
CA (1) CA1164459A (fi)
CH (1) CH653684A5 (fi)
DE (1) DE3152512T1 (fi)
DK (1) DK157193C (fi)
ES (1) ES507545A0 (fi)
FI (1) FI71145C (fi)
IT (1) IT8149680A0 (fi)
MX (1) MX6802E (fi)
NO (1) NO157819C (fi)
PH (1) PH17158A (fi)
PT (1) PT73959B (fi)
SE (1) SE440653B (fi)
SU (1) SU1215621A3 (fi)
WO (1) WO1982001706A1 (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537889A (en) * 1982-12-27 1985-08-27 Eli Lilly And Company Inotropic agents
US4636502A (en) * 1982-12-27 1987-01-13 Eli Lilly And Company Methods of producing a positive inotropic effect or vasodilation by administration of 2-phenyl imidazo pyrimidines and pyrazines
GB8305245D0 (en) * 1983-02-25 1983-03-30 Fujisawa Pharmaceutical Co Imidazo-heterocyclic compounds
US4533734A (en) * 1983-11-10 1985-08-06 Eli Lilly And Company Inotropic agents
PT79699B (en) * 1983-12-22 1986-12-10 Pfizer Process for preparing quinolone inotropic agents
NZ212209A (en) * 1984-05-29 1988-08-30 Pfizer Quinolone derivatives and pharmaceutical compositions
US4721721A (en) * 1984-12-18 1988-01-26 Rorer Pharmaceutical Corporation 6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses
FR2580646A1 (fr) * 1985-04-19 1986-10-24 Synthelabo Derives de 2(1h)-quinolinone, leur preparation et leur application en therapeutique
US4666913A (en) * 1985-11-22 1987-05-19 William H. Rorer, Inc. Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses
GB8529362D0 (en) * 1985-11-28 1986-01-02 Pfizer Ltd Quinolone cardiac stimulants
GB8619902D0 (en) * 1986-08-15 1986-09-24 Pfizer Ltd Quinolone cardiac stimulants
GB8709448D0 (en) * 1987-04-21 1987-05-28 Pfizer Ltd Heterobicyclic quinoline derivatives
EP0767790B1 (en) * 1994-06-20 2001-12-12 Takeda Chemical Industries, Ltd. Condensed imidazole compounds, their production and use
DE10117184A1 (de) * 2001-04-05 2002-10-17 Gruenenthal Gmbh Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen
DE10247271A1 (de) * 2002-10-10 2004-08-26 Grünenthal GmbH Substituierte C-Imidazo[1,2-a]pyridin-3-yle
PE20100399A1 (es) * 2003-04-02 2010-06-01 Novartis Ag Procedimiento para preparar oxi-(1h)-quinolin-2-onas 5-(alfa-haloacetil)-8-sustituidas
DE102005019181A1 (de) * 2005-04-25 2006-10-26 Novartis Ag Peptid-Deformylase (PDF) Inhibitoren 1
WO2010032195A1 (en) 2008-09-16 2010-03-25 Csir Imidazopyridines and imidazopyrimidines as hiv-i reverse transcriptase inhibitors
ES2362894B1 (es) * 2009-11-16 2012-05-21 Ferrer Internacional S.A. Procedimiento de preparación del �?cido 4-nitro-oxi-metil-benzoico.
EP3280716B1 (de) * 2015-04-08 2020-02-12 Bayer CropScience AG Imidazo[1,2-a]pyridin-2-yl-derivate als schädlingsbekämpfungsmittel und deren zwischenprodukte
CN108137514A (zh) 2015-07-30 2018-06-08 百时美施贵宝公司 芳基取代的二环杂芳基化合物
KR102468661B1 (ko) 2016-07-14 2022-11-17 브리스톨-마이어스 스큅 컴퍼니 Par4 억제제로서의 트리시클릭 헤테로아릴-치환된 퀴놀린 및 아자퀴놀린 화합물
EP3484878B1 (en) * 2016-07-14 2020-08-19 Bristol-Myers Squibb Company Bicyclic heteroaryl substituted compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1473819A (en) * 1976-01-28 1977-05-18 Gallardo Antonio Sa Derivatives of imidazo 1,2-a pyridine
ES482438A0 (es) * 1978-07-18 1980-04-01 Hoechst Ag Procedimiento para la preparacion de nuevos derivados de 2-(4-aminopiperidino)-3,4-dihidroquinoleina.
ES8100016A1 (es) * 1978-07-18 1980-04-01 Hoechst Ag Procedimiento para la preparacion de nuevos derivados de 1-(4-aminopiperidino)-3,4-dihidroisoquinoleina.
JPS5553284A (en) * 1978-10-12 1980-04-18 Yoshitomi Pharmaceut Ind Ltd Pyridazinone derivative
GB2031404A (en) * 1978-10-17 1980-04-23 Yoshitomi Pharmaceutical Pyridazinone compounds

Also Published As

Publication number Publication date
SE440653B (sv) 1985-08-12
ES8301967A1 (es) 1983-02-01
KR880001657B1 (ko) 1988-09-05
WO1982001706A1 (en) 1982-05-27
AU7808581A (en) 1982-06-07
PT73959B (en) 1983-04-18
ES507545A0 (es) 1983-02-01
CA1164459A (en) 1984-03-27
SE8204237L (sv) 1982-07-08
MX6802E (es) 1986-07-29
EP0052016B1 (en) 1984-09-05
AU547586B2 (en) 1985-10-24
SU1215621A3 (ru) 1986-02-28
KR830007644A (ko) 1983-11-04
DK307482A (da) 1982-07-08
SE8204237D0 (sv) 1982-07-08
IT8149680A0 (it) 1981-11-11
CH653684A5 (fr) 1986-01-15
ATA908381A (de) 1986-07-15
FI71145C (fi) 1986-11-24
AT382376B (de) 1987-02-25
FI822471L (fi) 1982-07-12
DE3152512T1 (de) 1982-11-18
EP0052016A1 (en) 1982-05-19
DE3152512C2 (fi) 1991-01-03
NO822391L (no) 1982-07-09
PH17158A (en) 1984-06-13
NO157819C (no) 1988-05-25
DK157193C (da) 1990-04-09
PT73959A (en) 1981-12-01
DK157193B (da) 1989-11-20
FI71145B (fi) 1986-08-14
NO157819B (no) 1988-02-15
US4414390A (en) 1983-11-08

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: OTSUKA PHARMACEUTICAL CO. LTD.