JPS5553284A - Pyridazinone derivative - Google Patents
Pyridazinone derivativeInfo
- Publication number
- JPS5553284A JPS5553284A JP12580178A JP12580178A JPS5553284A JP S5553284 A JPS5553284 A JP S5553284A JP 12580178 A JP12580178 A JP 12580178A JP 12580178 A JP12580178 A JP 12580178A JP S5553284 A JPS5553284 A JP S5553284A
- Authority
- JP
- Japan
- Prior art keywords
- lower alkyl
- compound
- activity
- blood platelet
- pyridazinone derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A compound of formula I (R1 is H or lower alkyl; R2 is H; R3 is H or lower alkyl; R4 is H or lower alkyl, or R2 and R4 together form a single bond; R5 is H or lower alkyl; R6 is H or lower alkanoyl; R7 is H or lower alkyl).
EXAMPLE: 6- ( 5-Hydroxymethyl-3-oxo-2, 3, 4, 5-tetrahydropyridazin-6-yl ) -1- methyl- 1,2,3,4-tetrahydroquinolin-2-one.
USE: The compound has blood platelet coagulation suppressing activity, blood platelet agglutination suppressing activity, membrane stabilizing activity, and hypotensive activity, and is useful as a remedy for thrombosis, hypertension, etc., or its synthetic intermediate.
PROCESS: A compound I wherein R6 is H, is prepared by reacting a compound II with a hydrazine derivative of R7NHNH2 or its hydrate, in a solvent such as methanol, under fefluxing.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12580178A JPS5553284A (en) | 1978-10-12 | 1978-10-12 | Pyridazinone derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12580178A JPS5553284A (en) | 1978-10-12 | 1978-10-12 | Pyridazinone derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5553284A true JPS5553284A (en) | 1980-04-18 |
JPS6257627B2 JPS6257627B2 (en) | 1987-12-02 |
Family
ID=14919228
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12580178A Granted JPS5553284A (en) | 1978-10-12 | 1978-10-12 | Pyridazinone derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5553284A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1982001706A1 (en) * | 1980-11-11 | 1982-05-27 | Tominaga Michiaki | Carbostyril compounds,composition containing same,and process for their preparation |
-
1978
- 1978-10-12 JP JP12580178A patent/JPS5553284A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1982001706A1 (en) * | 1980-11-11 | 1982-05-27 | Tominaga Michiaki | Carbostyril compounds,composition containing same,and process for their preparation |
Also Published As
Publication number | Publication date |
---|---|
JPS6257627B2 (en) | 1987-12-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB2126226B (en) | Pyridine derivatives | |
EP0289365A3 (en) | Novel nitrogen-containing compound | |
JPS5553284A (en) | Pyridazinone derivative | |
ES8505682A1 (en) | Beta-carbolin-3-carboxylic acid derivatives and methods of preparing them. | |
JPS52125168A (en) | Triazoline derivatives, method of preparing the same, and herbicides | |
JPS5553283A (en) | Pyridazinone derivative | |
JPS5549319A (en) | Remedy for suppression of blood platelet-agglutination | |
JPS57165369A (en) | Pyrazole derivative and its preparation | |
DE3462031D1 (en) | Alpha,alpha-dimethylphenylacetanilide derivatives, process for production thereof, and use thereof as insecticide | |
JPS5515455A (en) | 2-substituted-methyl-1,4-benzodioxane | |
GB1306454A (en) | Benzodiazepine derivatives | |
ES8504174A1 (en) | Hypotensive agents. | |
JPS5714578A (en) | 2-benzimidazolinone derivative | |
JPS54138571A (en) | Carbostyryl derivative | |
JPS54138585A (en) | Pyridazine derivative and its preparation | |
JPS5714574A (en) | Carbostyril derivative | |
JPS5566592A (en) | 7-alkoxythiazolo 3,2-a pyrimidine derivative, its preparation, and drug containing the same | |
JPS55141484A (en) | Pyridazine derivative | |
JPS55141483A (en) | Pyridazinone derivative | |
JPS57188574A (en) | Pyridazinone derivative | |
JPS55147278A (en) | Nicotinoylaminotriazine derivative | |
JPS51136682A (en) | Process for preparing 5-alkanoylcarbostyril derivatives. | |
JPS554322A (en) | 2-phenyl-substituted-1-phthalazone derivative | |
JPS5368790A (en) | Preparation of 1-(2'-tetrahydrofuryl)-5-fluorouracil | |
JPS57212165A (en) | Imidazole derivative and its preparation |