JPS5553284A - Pyridazinone derivative - Google Patents

Pyridazinone derivative

Info

Publication number
JPS5553284A
JPS5553284A JP12580178A JP12580178A JPS5553284A JP S5553284 A JPS5553284 A JP S5553284A JP 12580178 A JP12580178 A JP 12580178A JP 12580178 A JP12580178 A JP 12580178A JP S5553284 A JPS5553284 A JP S5553284A
Authority
JP
Japan
Prior art keywords
lower alkyl
compound
activity
blood platelet
pyridazinone derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12580178A
Other languages
Japanese (ja)
Other versions
JPS6257627B2 (en
Inventor
Tatsu Nakao
Noburo Setoguchi
Osamu Yaoka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP12580178A priority Critical patent/JPS5553284A/en
Publication of JPS5553284A publication Critical patent/JPS5553284A/en
Publication of JPS6257627B2 publication Critical patent/JPS6257627B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:A compound of formula I (R1 is H or lower alkyl; R2 is H; R3 is H or lower alkyl; R4 is H or lower alkyl, or R2 and R4 together form a single bond; R5 is H or lower alkyl; R6 is H or lower alkanoyl; R7 is H or lower alkyl).
EXAMPLE: 6- ( 5-Hydroxymethyl-3-oxo-2, 3, 4, 5-tetrahydropyridazin-6-yl ) -1- methyl- 1,2,3,4-tetrahydroquinolin-2-one.
USE: The compound has blood platelet coagulation suppressing activity, blood platelet agglutination suppressing activity, membrane stabilizing activity, and hypotensive activity, and is useful as a remedy for thrombosis, hypertension, etc., or its synthetic intermediate.
PROCESS: A compound I wherein R6 is H, is prepared by reacting a compound II with a hydrazine derivative of R7NHNH2 or its hydrate, in a solvent such as methanol, under fefluxing.
COPYRIGHT: (C)1980,JPO&Japio
JP12580178A 1978-10-12 1978-10-12 Pyridazinone derivative Granted JPS5553284A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12580178A JPS5553284A (en) 1978-10-12 1978-10-12 Pyridazinone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12580178A JPS5553284A (en) 1978-10-12 1978-10-12 Pyridazinone derivative

Publications (2)

Publication Number Publication Date
JPS5553284A true JPS5553284A (en) 1980-04-18
JPS6257627B2 JPS6257627B2 (en) 1987-12-02

Family

ID=14919228

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12580178A Granted JPS5553284A (en) 1978-10-12 1978-10-12 Pyridazinone derivative

Country Status (1)

Country Link
JP (1) JPS5553284A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982001706A1 (en) * 1980-11-11 1982-05-27 Tominaga Michiaki Carbostyril compounds,composition containing same,and process for their preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982001706A1 (en) * 1980-11-11 1982-05-27 Tominaga Michiaki Carbostyril compounds,composition containing same,and process for their preparation

Also Published As

Publication number Publication date
JPS6257627B2 (en) 1987-12-02

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