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Individual
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Individual
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Priority to JP7643478ApriorityCriticalpatent/JPS554322A/en
Publication of JPS554322ApublicationCriticalpatent/JPS554322A/en
USE: Synthetic intermediate of remedy and prophylactic for ischemic heart diseases, thrombotic diseases, etc.; for example, intermediate of 2-phenyl-4-hydroxymethyl-1- phthalazone derivative.
PROCESS: Reaction of a compound II with phenylhydrazine affords the objective compound I. The compound II can be obtained, e.g. by oxidizing the corresponding 3-hydroxyphthalide derivative with potassium permanganate under alkaline condition.