JPS5543027A - 2-pyridyl-1-phthalazone derivative - Google Patents

2-pyridyl-1-phthalazone derivative

Info

Publication number
JPS5543027A
JPS5543027A JP11600878A JP11600878A JPS5543027A JP S5543027 A JPS5543027 A JP S5543027A JP 11600878 A JP11600878 A JP 11600878A JP 11600878 A JP11600878 A JP 11600878A JP S5543027 A JPS5543027 A JP S5543027A
Authority
JP
Japan
Prior art keywords
derivative
formula
pyridyl
phthalazone
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11600878A
Other languages
Japanese (ja)
Inventor
Masayuki Ishikawa
Masao Eguchi
Hiromichi Tanaka
Shigeru Ito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP11600878A priority Critical patent/JPS5543027A/en
Publication of JPS5543027A publication Critical patent/JPS5543027A/en
Pending legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A 2-pyridyl-2-phthalazone derivative of formula I (R1 and R2 are lower alkyl groups; R3 is alkyl group; R4 and R are H or lower alkyl groups).
EXAMPLE: 7-Ethoxycarbonyl-6,8-dimethyl-4-carboxy-2-(2-pyridyl)-1-phthalazone.
USE: An intermediate for the synthesis of 2-pyridyl-4-hydroxymethyl-1-phthalazone derivative useful for preventing and treating ischemic heart, cerebral vascular trouble and thrombotic diseases.
PROCESS: A phthalonic acid derivative of formula II is reacted with a pyridylhydrazine derivative of formula III in a solvent, and if necessary the reaction product is esterified to give the compound of formula I. The compound of formula II can be obtained by oxidizing a 3-hydroxy-3-methyl-phthalide derivative with an oxidizing agent, e.g. potassium permanganate.
COPYRIGHT: (C)1980,JPO&Japio
JP11600878A 1978-09-22 1978-09-22 2-pyridyl-1-phthalazone derivative Pending JPS5543027A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11600878A JPS5543027A (en) 1978-09-22 1978-09-22 2-pyridyl-1-phthalazone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11600878A JPS5543027A (en) 1978-09-22 1978-09-22 2-pyridyl-1-phthalazone derivative

Publications (1)

Publication Number Publication Date
JPS5543027A true JPS5543027A (en) 1980-03-26

Family

ID=14676537

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11600878A Pending JPS5543027A (en) 1978-09-22 1978-09-22 2-pyridyl-1-phthalazone derivative

Country Status (1)

Country Link
JP (1) JPS5543027A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2203098B (en) * 1987-04-08 1991-12-11 Brother Ind Ltd A printer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2203098B (en) * 1987-04-08 1991-12-11 Brother Ind Ltd A printer

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