SE8204237L - Karbostyrilforeningar, kompositioner innehallande dessa samt forfaranden for framstellning derav - Google Patents
Karbostyrilforeningar, kompositioner innehallande dessa samt forfaranden for framstellning deravInfo
- Publication number
- SE8204237L SE8204237L SE8204237A SE8204237A SE8204237L SE 8204237 L SE8204237 L SE 8204237L SE 8204237 A SE8204237 A SE 8204237A SE 8204237 A SE8204237 A SE 8204237A SE 8204237 L SE8204237 L SE 8204237L
- Authority
- SE
- Sweden
- Prior art keywords
- pct
- preparing
- carbostyric
- associations
- procedures
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- LISFMEBWQUVKPJ-UHFFFAOYSA-N carbostyril Natural products C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 abstract 1
- -1 carbostyril compound Chemical class 0.000 abstract 1
- 230000003177 cardiotonic effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/28—Alcohols; Ethers thereof with halogen atoms or nitro radicals in positions 5, 6 or 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/32—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55159016A JPS5782390A (en) | 1980-11-11 | 1980-11-11 | Carbostyril derivative |
| JP55179950A JPS57102888A (en) | 1980-12-18 | 1980-12-18 | Carbostyril derivative |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8204237L true SE8204237L (sv) | 1982-07-08 |
| SE8204237D0 SE8204237D0 (sv) | 1982-07-08 |
| SE440653B SE440653B (sv) | 1985-08-12 |
Family
ID=26485945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8204237A SE440653B (sv) | 1980-11-11 | 1982-07-08 | Karbostyrilforeningar |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4414390A (sv) |
| EP (1) | EP0052016B1 (sv) |
| KR (1) | KR880001657B1 (sv) |
| AT (1) | AT382376B (sv) |
| AU (1) | AU547586B2 (sv) |
| CA (1) | CA1164459A (sv) |
| CH (1) | CH653684A5 (sv) |
| DE (1) | DE3152512T1 (sv) |
| DK (1) | DK157193C (sv) |
| ES (1) | ES8301967A1 (sv) |
| FI (1) | FI71145C (sv) |
| IT (1) | IT8149680A0 (sv) |
| MX (1) | MX6802E (sv) |
| NO (1) | NO157819C (sv) |
| PH (1) | PH17158A (sv) |
| PT (1) | PT73959B (sv) |
| SE (1) | SE440653B (sv) |
| SU (1) | SU1215621A3 (sv) |
| WO (1) | WO1982001706A1 (sv) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4537889A (en) * | 1982-12-27 | 1985-08-27 | Eli Lilly And Company | Inotropic agents |
| US4636502A (en) * | 1982-12-27 | 1987-01-13 | Eli Lilly And Company | Methods of producing a positive inotropic effect or vasodilation by administration of 2-phenyl imidazo pyrimidines and pyrazines |
| GB8305245D0 (en) * | 1983-02-25 | 1983-03-30 | Fujisawa Pharmaceutical Co | Imidazo-heterocyclic compounds |
| US4533734A (en) * | 1983-11-10 | 1985-08-06 | Eli Lilly And Company | Inotropic agents |
| PT79699B (en) * | 1983-12-22 | 1986-12-10 | Pfizer | Process for preparing quinolone inotropic agents |
| GR851296B (sv) * | 1984-05-29 | 1985-11-25 | Pfizer | |
| US4721721A (en) * | 1984-12-18 | 1988-01-26 | Rorer Pharmaceutical Corporation | 6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses |
| FR2580646A1 (fr) * | 1985-04-19 | 1986-10-24 | Synthelabo | Derives de 2(1h)-quinolinone, leur preparation et leur application en therapeutique |
| US4666913A (en) * | 1985-11-22 | 1987-05-19 | William H. Rorer, Inc. | Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses |
| GB8529362D0 (en) * | 1985-11-28 | 1986-01-02 | Pfizer Ltd | Quinolone cardiac stimulants |
| GB8619902D0 (en) * | 1986-08-15 | 1986-09-24 | Pfizer Ltd | Quinolone cardiac stimulants |
| GB8709448D0 (en) * | 1987-04-21 | 1987-05-28 | Pfizer Ltd | Heterobicyclic quinoline derivatives |
| AU2682695A (en) * | 1994-06-20 | 1996-01-15 | Takeda Chemical Industries Ltd. | Condensed imidazole compounds, their production and use |
| DE10117184A1 (de) * | 2001-04-05 | 2002-10-17 | Gruenenthal Gmbh | Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen |
| DE10247271A1 (de) * | 2002-10-10 | 2004-08-26 | Grünenthal GmbH | Substituierte C-Imidazo[1,2-a]pyridin-3-yle |
| PE20100399A1 (es) * | 2003-04-02 | 2010-06-01 | Novartis Ag | Procedimiento para preparar oxi-(1h)-quinolin-2-onas 5-(alfa-haloacetil)-8-sustituidas |
| DE102005019181A1 (de) * | 2005-04-25 | 2006-10-26 | Novartis Ag | Peptid-Deformylase (PDF) Inhibitoren 1 |
| WO2010032195A1 (en) * | 2008-09-16 | 2010-03-25 | Csir | Imidazopyridines and imidazopyrimidines as hiv-i reverse transcriptase inhibitors |
| ES2362894B1 (es) * | 2009-11-16 | 2012-05-21 | Ferrer Internacional S.A. | Procedimiento de preparación del �?cido 4-nitro-oxi-metil-benzoico. |
| JP6730309B2 (ja) * | 2015-04-08 | 2020-07-29 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | 有害生物防除剤としての縮合二環式ヘテロ環誘導体及び中間体生成物 |
| EP3328839A1 (en) | 2015-07-30 | 2018-06-06 | Bristol-Myers Squibb Company | Aryl substituted bicyclic heteroaryl compounds |
| ES2823127T3 (es) | 2016-07-14 | 2021-05-06 | Bristol Myers Squibb Co | Compuestos tricíclicos de quinolina y azaquinolina sustituidos con heteroarilo como inhibidores de PAR4 |
| WO2018013774A1 (en) * | 2016-07-14 | 2018-01-18 | Bristol-Myers Squibb Company | Bicyclic heteroaryl substituted compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1473819A (en) * | 1976-01-28 | 1977-05-18 | Gallardo Antonio Sa | Derivatives of imidazo 1,2-a pyridine |
| ES8100016A1 (es) * | 1978-07-18 | 1980-04-01 | Hoechst Ag | Procedimiento para la preparacion de nuevos derivados de 1-(4-aminopiperidino)-3,4-dihidroisoquinoleina. |
| ES8100015A1 (es) * | 1978-07-18 | 1980-04-01 | Hoechst Ag | Procedimiento para la preparacion de nuevos derivados de 2-(4-aminopiperidino)-3,4-dihidroquinoleina. |
| JPS5553284A (en) * | 1978-10-12 | 1980-04-18 | Yoshitomi Pharmaceut Ind Ltd | Pyridazinone derivative |
| GB2031404A (en) * | 1978-10-17 | 1980-04-23 | Yoshitomi Pharmaceutical | Pyridazinone compounds |
-
1981
- 1981-10-29 CA CA000389034A patent/CA1164459A/en not_active Expired
- 1981-11-10 PT PT73959A patent/PT73959B/pt not_active IP Right Cessation
- 1981-11-10 PH PH26478A patent/PH17158A/en unknown
- 1981-11-11 WO PCT/JP1981/000328 patent/WO1982001706A1/ja active IP Right Grant
- 1981-11-11 CH CH4324/82A patent/CH653684A5/fr not_active IP Right Cessation
- 1981-11-11 ES ES507545A patent/ES8301967A1/es not_active Expired
- 1981-11-11 US US06/403,582 patent/US4414390A/en not_active Expired - Lifetime
- 1981-11-11 IT IT8149680A patent/IT8149680A0/it unknown
- 1981-11-11 MX MX819760U patent/MX6802E/es unknown
- 1981-11-11 AT AT0908381A patent/AT382376B/de not_active IP Right Cessation
- 1981-11-11 EP EP81305344A patent/EP0052016B1/en not_active Expired
- 1981-11-11 AU AU78085/81A patent/AU547586B2/en not_active Ceased
- 1981-11-11 DE DE813152512T patent/DE3152512T1/de active Granted
- 1981-11-11 KR KR1019810004359A patent/KR880001657B1/ko active
-
1982
- 1982-07-08 SE SE8204237A patent/SE440653B/sv not_active IP Right Cessation
- 1982-07-08 DK DK307482A patent/DK157193C/da not_active IP Right Cessation
- 1982-07-09 NO NO82822391A patent/NO157819C/no unknown
- 1982-07-11 SU SU823466402A patent/SU1215621A3/ru active
- 1982-07-12 FI FI822471A patent/FI71145C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO822391L (no) | 1982-07-09 |
| ES507545A0 (es) | 1983-02-01 |
| FI822471L (fi) | 1982-07-12 |
| AU547586B2 (en) | 1985-10-24 |
| MX6802E (es) | 1986-07-29 |
| KR830007644A (ko) | 1983-11-04 |
| PH17158A (en) | 1984-06-13 |
| CH653684A5 (fr) | 1986-01-15 |
| PT73959A (en) | 1981-12-01 |
| DK157193B (da) | 1989-11-20 |
| KR880001657B1 (ko) | 1988-09-05 |
| CA1164459A (en) | 1984-03-27 |
| AT382376B (de) | 1987-02-25 |
| NO157819C (no) | 1988-05-25 |
| ES8301967A1 (es) | 1983-02-01 |
| EP0052016B1 (en) | 1984-09-05 |
| FI71145C (fi) | 1986-11-24 |
| DK307482A (da) | 1982-07-08 |
| ATA908381A (de) | 1986-07-15 |
| SU1215621A3 (ru) | 1986-02-28 |
| SE8204237D0 (sv) | 1982-07-08 |
| NO157819B (no) | 1988-02-15 |
| DE3152512T1 (de) | 1982-11-18 |
| PT73959B (en) | 1983-04-18 |
| SE440653B (sv) | 1985-08-12 |
| IT8149680A0 (it) | 1981-11-11 |
| DK157193C (da) | 1990-04-09 |
| FI71145B (fi) | 1986-08-14 |
| FI822471A0 (fi) | 1982-07-12 |
| WO1982001706A1 (en) | 1982-05-27 |
| EP0052016A1 (en) | 1982-05-19 |
| AU7808581A (en) | 1982-06-07 |
| US4414390A (en) | 1983-11-08 |
| DE3152512C2 (sv) | 1991-01-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE8204237L (sv) | Karbostyrilforeningar, kompositioner innehallande dessa samt forfaranden for framstellning derav | |
| SE8302693L (sv) | Heterocykliska foreningar | |
| BR9303993A (pt) | Composto, processo para preparar o mesmo e composição farmacêutica | |
| ES485188A1 (es) | Procedimiento para preparar 1-piperazina-carboxamidas y car-botiamidas | |
| SE8700498D0 (sv) | Novel pharmaceologically active compounds | |
| MD4B1 (ro) | Remediu erbicid | |
| ES2074846T3 (es) | Nuevas naftil-etil-ureas y naftil-etil-tioureas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen. | |
| SE8200916L (sv) | Karbostyrilderivat, forfarande for framstellning derav och hjertsterkande komposition som innehaller detsamma | |
| ATE5967T1 (de) | 3,4-diarylisoxazol-5-essigsaeure-verbindungen, verfahren zu deren herstellung und sie enthaltende arzneimittel. | |
| IL57577A0 (en) | 1,2-dihydroquinolin-2-one derivatives,process for their preparation and pharmaceutical compositions containing the same | |
| SE7707341L (sv) | 4-hydroxifenylalkanolamin-derivat och forfarande for framstellning derav | |
| ES8305344A1 (es) | Un procedimiento para la produccion de un derivado de piperazina. | |
| NO960632L (no) | Nye bis-naftalimider for behandling av kreft | |
| DE69330601D1 (de) | Serotoninergische ergolin derivate | |
| AU530678B2 (en) | Phosphono-hydroxy-acetic acid | |
| ES8304978A1 (es) | "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos". | |
| DK532679A (da) | Fremgangsmaade til fremstilling af 2-aryl-3,4-diaza-bicyclo (4,1,0)hepten-(2)-on-(5). | |
| ES8501607A1 (es) | Procedimiento para la obtencion de heterociclos nitrogenosos de 5 miembros | |
| DE3380517D1 (en) | New compounds, pharmaceutical preparations containing same and process for their preparation | |
| GB1126002A (en) | New basic ethers and process for preparing same | |
| NZ220800A (en) | Tetrahydrobenzothiazoles and pharmaceutical compositions | |
| ES8307778A1 (es) | Procedimiento para preparar difenilbutil-1-piperazinocarboxilatos. | |
| ES8106128A1 (es) | Un procedimiento para la preparacion de derivados de ciclo- hexadieno | |
| NO904708L (no) | Fremgangsmaate for fremstilling av derivater av 2-(3-pyridyl)-2-tetrahydrotiopyrankarbotioamid-1-oksid-(1r-2r). | |
| SE7907656L (sv) | 3,4-dihydroxikanelaldehydderivat |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAL | Patent in force |
Ref document number: 8204237-5 Format of ref document f/p: F |
|
| NUG | Patent has lapsed |
Ref document number: 8204237-5 Format of ref document f/p: F |