FI79115C - Foerfarande foer framstaellning av 1-etoxikarbonyloxietylestern av 6-(d-(-)- -amino- -fenylacetamido) penicillansyra. - Google Patents

Foerfarande foer framstaellning av 1-etoxikarbonyloxietylestern av 6-(d-(-)- -amino- -fenylacetamido) penicillansyra. Download PDF

Info

Publication number
FI79115C
FI79115C FI832363A FI832363A FI79115C FI 79115 C FI79115 C FI 79115C FI 832363 A FI832363 A FI 832363A FI 832363 A FI832363 A FI 832363A FI 79115 C FI79115 C FI 79115C
Authority
FI
Finland
Prior art keywords
reaction
formula
bromide
ampicillin
carbonate
Prior art date
Application number
FI832363A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI79115B (fi
FI832363A0 (fi
FI832363L (fi
Inventor
Luigi Ratti
Derek Reginald Palmer
Robert Graham Tyson
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT22141/82A external-priority patent/IT1190897B/it
Priority claimed from GB838300331A external-priority patent/GB8300331D0/en
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of FI832363A0 publication Critical patent/FI832363A0/fi
Publication of FI832363L publication Critical patent/FI832363L/fi
Priority to FI873710A priority Critical patent/FI79832C/fi
Priority to FI885863A priority patent/FI86182C/fi
Publication of FI79115B publication Critical patent/FI79115B/fi
Application granted granted Critical
Publication of FI79115C publication Critical patent/FI79115C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00—Preparation of esters of carbonic or haloformic acids
    • C07C68/02—Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96—Esters of carbonic or haloformic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI832363A 1982-06-29 1983-06-28 Foerfarande foer framstaellning av 1-etoxikarbonyloxietylestern av 6-(d-(-)- -amino- -fenylacetamido) penicillansyra. FI79115C (fi)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI873710A FI79832C (fi) 1982-06-29 1987-08-26 A-bromdietylkarbonat och dess anvaendning vid framstaellning av etoxikarbonyloxietylestern av penicillin g.
FI885863A FI86182C (fi) 1982-06-29 1988-12-19 Foerfarande foer framstaellning av 1-etoxikarbonyloxietylestern av 6-(d-(-)- -amino- -fenylacetamido) penicillansyra.

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
IT2214182 1982-06-29
IT22141/82A IT1190897B (it) 1982-06-29 1982-06-29 Procedimento per la preparazione dell'estere 1-etossicarbonilossietilico dell'acido 6-(d(-)-alfa aminoalfa fenilacetamido)-penicillanico
GB8226751 1982-09-20
GB8226751 1982-09-20
GB8228622 1982-10-06
GB8228622 1982-10-06
GB8232629 1982-11-16
GB8232629 1982-11-16
GB8300331 1983-01-07
GB838300331A GB8300331D0 (en) 1983-01-07 1983-01-07 Preparation of bromo carbonates

Publications (4)

Publication Number Publication Date
FI832363A0 FI832363A0 (fi) 1983-06-28
FI832363L FI832363L (fi) 1983-12-30
FI79115B FI79115B (fi) 1989-07-31
FI79115C true FI79115C (fi) 1989-11-10

Family

ID=27516485

Family Applications (1)

Application Number Title Priority Date Filing Date
FI832363A FI79115C (fi) 1982-06-29 1983-06-28 Foerfarande foer framstaellning av 1-etoxikarbonyloxietylestern av 6-(d-(-)- -amino- -fenylacetamido) penicillansyra.

Country Status (23)

Country Link
JP (2) JPH0730082B2 (no)
AT (1) AT383128B (no)
AU (1) AU566803B2 (no)
BG (3) BG38336A3 (no)
CH (2) CH657620B (no)
CY (2) CY1519A (no)
DD (1) DD211561A5 (no)
DE (2) DE3322783A1 (no)
DK (3) DK160039C (no)
FI (1) FI79115C (no)
FR (1) FR2543957B1 (no)
GB (3) GB2168050A (no)
GR (1) GR78585B (no)
HU (1) HU191534B (no)
IE (1) IE56712B1 (no)
IL (1) IL68992A (no)
IS (1) IS1361B6 (no)
NL (1) NL194081C (no)
NO (3) NO157696C (no)
NZ (1) NZ204736A (no)
PT (1) PT76944B (no)
SE (2) SE454879B (no)
YU (2) YU43926B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2573756B1 (fr) * 1984-11-23 1987-01-16 Poudres & Explosifs Ste Nale Procede de preparation des carbonates de bromo-1 ethyle et d'hydrocarbyle et nouveaux carbonates de bromo-1 ethyle et d'hydrocarbyle

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH516593A (de) * 1967-09-29 1971-12-15 Leo Pharm Prod Ltd Verfahren zur Herstellung von neuen Estern von a-Aminobenzyl-penicillin
US3873521A (en) * 1970-09-17 1975-03-25 Astra Laekemedel Ab Esters of {60 -amino penicillins
IE35648B1 (en) * 1970-09-25 1976-04-14 Beecham Group Ltd Penicillins
DE2161420A1 (de) * 1970-12-30 1972-07-27 Toyama Chemical Co. Ltd., Tokio Penicillinderivate und Verfahren zu deren Herstellung
DE2228670A1 (de) * 1971-06-15 1973-01-11 Yamanouchi Pharma Co Ltd Neue oxymethylesterderivate von penicillin und cephalosporin
NZ169577A (en) * 1972-02-15 1984-09-28 Ayerst Mckenna & Harrison Preparation of lh-and fsh-releasing hormone,intermediates,and pharmaceutical compositions
GB1425571A (en) * 1972-03-13 1976-02-18 Astra Laekemedel Ab Penicillins and cephaosporins
GB1426717A (en) * 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
GB1426869A (en) * 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
SE397981B (sv) * 1973-02-19 1977-11-28 Astra Laekemedel Ab Nya tetraalkylammoniumsalter av 6-aminopenicillansyra och av bensylpenicillin avsedda att anvendas som mellanprodukter vid framstellning av vissa estrar av 6-aminopenicillansyra och av bensylpenicillin
GB1565656A (en) * 1975-12-13 1980-04-23 Beecham Group Ltd Preparation of substituted penicillin acid esters
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
JPS5444694A (en) * 1977-09-06 1979-04-09 Kou Kamata Aminobenzylpenicillin derivative
NO832376L (no) * 1982-06-30 1984-01-02 Glaxo Group Ltd Cephalosporin-antibiotika.
ATE43833T1 (de) * 1982-11-04 1989-06-15 Astra Laekemedel Ab Verfahren zur herstellung des 1'ethoxycarbonyloxyethylestersvon benzylpenicillin.

Also Published As

Publication number Publication date
DK296683A (da) 1983-12-30
GB8528958D0 (en) 1986-01-02
FI79115B (fi) 1989-07-31
BG38335A3 (en) 1985-11-15
YU141583A (en) 1986-06-30
ATA238483A (de) 1986-10-15
DK106090A (da) 1990-04-30
GB2169287A (en) 1986-07-09
NL194081C (nl) 2001-06-05
AU566803B2 (en) 1987-10-29
DE3322783A1 (de) 1984-02-09
JPH0819052B2 (ja) 1996-02-28
DK167807B1 (da) 1993-12-20
JPH0543583A (ja) 1993-02-23
SE454879B (sv) 1988-06-06
DK159821B (da) 1990-12-10
GB8522827D0 (en) 1985-10-23
YU43693B (en) 1989-10-31
CH657620B (no) 1986-09-15
IS1361B6 (is) 1989-05-25
FI832363A0 (fi) 1983-06-28
DK105990A (da) 1990-04-30
FR2543957B1 (fr) 1986-10-24
DD211561A5 (de) 1984-07-18
NO851255L (no) 1983-12-30
DE3348299C2 (no) 1990-12-20
GB2168050A (en) 1986-06-11
YU43926B (en) 1989-12-31
FR2543957A1 (fr) 1984-10-12
YU21886A (en) 1987-10-31
DK105990D0 (da) 1990-04-30
FI832363L (fi) 1983-12-30
DK160039C (da) 1991-06-10
GB8522826D0 (en) 1985-10-23
CY1520A (en) 1990-11-16
JPH0730082B2 (ja) 1995-04-05
CY1519A (en) 1990-11-16
NO157696C (no) 1988-05-04
GB2168699A (en) 1986-06-25
GR78585B (no) 1984-09-27
SE9100548D0 (sv) 1991-02-26
NO851254L (no) 1983-12-30
GB2168699B (en) 1987-04-15
NO157696B (no) 1988-01-25
SE503843C2 (sv) 1996-09-16
NZ204736A (en) 1986-11-12
AT383128B (de) 1987-05-25
BG38336A3 (en) 1985-11-15
CH656377A5 (de) 1986-06-30
PT76944B (en) 1986-04-09
BG37527A3 (en) 1985-06-14
IE831445L (en) 1983-12-29
PT76944A (en) 1983-07-01
SE8303414D0 (sv) 1983-06-15
IS2825A7 (is) 1984-07-08
GB2169287B (en) 1987-04-08
SE8303414L (sv) 1983-12-30
DK160039B (da) 1991-01-21
DK106090D0 (da) 1990-04-30
JPH0717918A (ja) 1995-01-20
DE3322783C2 (no) 1991-01-31
DK159821C (da) 1991-04-29
DK296683D0 (da) 1983-06-28
IL68992A (en) 1991-06-10
NO832351L (no) 1983-12-30
NL8302286A (nl) 1984-01-16
HU191534B (en) 1987-03-30
AU1632883A (en) 1984-01-05
IE56712B1 (en) 1991-11-20
NL194081B (nl) 2001-02-01
SE9100548L (sv) 1991-02-26

Similar Documents

Publication Publication Date Title
EP0019345A1 (en) Process for the preparation of a (D-alpha-amino-(p-hydroxyphenyl)-acetamido) group containing cephalosporanic acid derivatives
LU86461A1 (fr) Procede de deprotection des esters et ethers allyliques
FI79115C (fi) Foerfarande foer framstaellning av 1-etoxikarbonyloxietylestern av 6-(d-(-)- -amino- -fenylacetamido) penicillansyra.
DK149129B (da) Fremgangsmaade til fremstilling af 6-(d-(-)alfa-amino-alfa-(p-hydroxyphenyl)acetamido)penicillansyre hydrat eller salte deraf
JPH045032B2 (no)
KR102588221B1 (ko) 2-브로모글루타르산 디에스테르를 합성하는 방법
JPS585199B2 (ja) 置換ペニシリン類の製造方法
CN100543027C (zh) 制备用于合成头孢菌素的中间体的方法
LU84882A1 (fr) Perfectionnements apportes a la preparation d'antibiotiques
KR100477763B1 (ko) 세파트리진 프로필렌글리콜 중간체의 신규한 제조방법
JPH0478638B2 (no)
US4301072A (en) Process for preparing aminopenicillins
US4366098A (en) Process for preparing aminopenicillins
US4231954A (en) Dane salt and process for preparing aminopenicillins therefrom
FR2532933A1 (fr) Perfectionnements apportes a la preparation d'antibiotiques
JPS59164771A (ja) 塩素化アゼチジノン誘導体の製造方法
JPS585902B2 (ja) β↓−ニトロスチレン誘導体
FI72727B (fi) Foerfarande foer framstaellning av cefalosporansyraderivat innehaollande en 7-(d- -amino-(p-hydroxifenyl)-acetamido-grupp.
DE3348300C2 (de) Verwendung von alpha-Bromdiethylcarbonat
GB2177698A (en) Improvements in the preparation of antibiotics
JPH0662635B2 (ja) セフアロスポリン類の新規製造法
JPH0356482A (ja) 光学活性な２―フタルイミドオキシーフェニル酢酸誘導体およびその製造方法
Human et al. S 14. Esters of N-substituted phthalamic acids. Preparation and use in the optical resolutions of alcohols and amines
NZ216265A (en) Alpha-bromodiethylcarbonate and its manufacture
BE738131A (en) Certain alpha-amino bicyclic beta-lactam carboxylic

Legal Events

Date Code Title Description
MA Patent expired

Owner name: ASTRA LAEKEMEDEL AKTIEBOLAG