GB2168699B - A-bromodiethyl carbonate and its use in the preparation of antibiotics - Google Patents

A-bromodiethyl carbonate and its use in the preparation of antibiotics

Info

Publication number
GB2168699B
GB2168699B GB08522826A GB8522826A GB2168699B GB 2168699 B GB2168699 B GB 2168699B GB 08522826 A GB08522826 A GB 08522826A GB 8522826 A GB8522826 A GB 8522826A GB 2168699 B GB2168699 B GB 2168699B
Authority
GB
United Kingdom
Prior art keywords
antibiotics
preparation
bromodiethyl carbonate
bromodiethyl
carbonate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08522826A
Other versions
GB8522826D0 (en
GB2168699A (en
Inventor
Luigi Ratti
Derek Reginald Palmer
Robert Graham Tyson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Lakemedel AB
Original Assignee
Astra Lakemedel AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT22141/82A external-priority patent/IT1190897B/en
Priority claimed from GB838300331A external-priority patent/GB8300331D0/en
Application filed by Astra Lakemedel AB filed Critical Astra Lakemedel AB
Publication of GB8522826D0 publication Critical patent/GB8522826D0/en
Publication of GB2168699A publication Critical patent/GB2168699A/en
Application granted granted Critical
Publication of GB2168699B publication Critical patent/GB2168699B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00—Preparation of esters of carbonic or haloformic acids
    • C07C68/02—Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96—Esters of carbonic or haloformic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB08522826A 1982-06-29 1985-09-16 A-bromodiethyl carbonate and its use in the preparation of antibiotics Expired GB2168699B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IT22141/82A IT1190897B (en) 1982-06-29 1982-06-29 PROCEDURE FOR THE PREPARATION OF THE 1-ETHOXYCARBONYLOXYETHYL ACID ACID 6- (D (-) - ALPHA AMINOALPHA-PHENYLACETAMIDE) -PENICILLANIC
GB8226751 1982-09-20
GB8228622 1982-10-06
GB8232629 1982-11-16
GB838300331A GB8300331D0 (en) 1983-01-07 1983-01-07 Preparation of bromo carbonates

Publications (3)

Publication Number Publication Date
GB8522826D0 GB8522826D0 (en) 1985-10-23
GB2168699A GB2168699A (en) 1986-06-25
GB2168699B true GB2168699B (en) 1987-04-15

Family

ID=27516485

Family Applications (3)

Application Number Title Priority Date Filing Date
GB08528958A Withdrawn GB2168050A (en) 1982-06-29 1983-06-27 Intermediates useful in the preparation of antibiotics
GB08522827A Expired GB2169287B (en) 1982-06-29 1985-09-16 Improvements in the preparation of ampicillin
GB08522826A Expired GB2168699B (en) 1982-06-29 1985-09-16 A-bromodiethyl carbonate and its use in the preparation of antibiotics

Family Applications Before (2)

Application Number Title Priority Date Filing Date
GB08528958A Withdrawn GB2168050A (en) 1982-06-29 1983-06-27 Intermediates useful in the preparation of antibiotics
GB08522827A Expired GB2169287B (en) 1982-06-29 1985-09-16 Improvements in the preparation of ampicillin

Country Status (23)

Country Link
JP (2) JPH0819052B2 (en)
AT (1) AT383128B (en)
AU (1) AU566803B2 (en)
BG (3) BG38335A3 (en)
CH (2) CH657620B (en)
CY (2) CY1520A (en)
DD (1) DD211561A5 (en)
DE (2) DE3322783A1 (en)
DK (3) DK160039C (en)
FI (1) FI79115C (en)
FR (1) FR2543957B1 (en)
GB (3) GB2168050A (en)
GR (1) GR78585B (en)
HU (1) HU191534B (en)
IE (1) IE56712B1 (en)
IL (1) IL68992A (en)
IS (1) IS1361B6 (en)
NL (1) NL194081C (en)
NO (3) NO157696C (en)
NZ (1) NZ204736A (en)
PT (1) PT76944B (en)
SE (2) SE454879B (en)
YU (2) YU43926B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2573756B1 (en) * 1984-11-23 1987-01-16 Poudres & Explosifs Ste Nale PROCESS FOR THE PREPARATION OF BROMO-1 ETHYL AND HYDROCARBYL CARBONATES AND NOVEL BROMO-1 ETHYL AND HYDROCARBYL CARBONATES

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH516593A (en) * 1967-09-29 1971-12-15 Leo Pharm Prod Ltd Alpha amino-benzyl penicillins - useful as oral antibiotics
US3873521A (en) * 1970-09-17 1975-03-25 Astra Laekemedel Ab Esters of {60 -amino penicillins
IE35648B1 (en) * 1970-09-25 1976-04-14 Beecham Group Ltd Penicillins
DE2161420A1 (en) * 1970-12-30 1972-07-27 Toyama Chemical Co. Ltd., Tokio Penicillin derivatives and processes for their preparation
BE784800A (en) * 1971-06-15 1972-10-02 Yamanouchi Pharma Co Ltd PROCESS FOR PREPARING NEW OXYMETHYL ESTERS OF PENICILLIN AND CEPHALOSPORIN
IL48514A (en) * 1972-02-15 1976-08-31 Mckenna A Hexapeptide intermediate for the preparation of the lh-and fsh-releasing hormone
GB1426717A (en) * 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
GB1425571A (en) * 1972-03-13 1976-02-18 Astra Laekemedel Ab Penicillins and cephaosporins
GB1426869A (en) * 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
SE397981B (en) * 1973-02-19 1977-11-28 Astra Laekemedel Ab NEW TETRAALKYLAMMONIUM SALTS OF 6-AMINOPENICILLANIC ACID AND OF BENZYLPENICILLIN INTENDED TO BE USED AS INTERMEDIATE PRODUCTS IN THE PREPARATION OF CERTAIN ESTERS OF 6-AMINOPENICILLANIC ACID AND OF BENZYLPENIC
GB1565656A (en) * 1975-12-13 1980-04-23 Beecham Group Ltd Preparation of substituted penicillin acid esters
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
JPS5444694A (en) * 1977-09-06 1979-04-09 Kou Kamata Aminobenzylpenicillin derivative
NO832376L (en) * 1982-06-30 1984-01-02 Glaxo Group Ltd Cephalosporin ANTIBIOTICS.
EP0108547B1 (en) * 1982-11-04 1989-06-07 Astra Lakemedel Aktiebolag Process for the preparation of the 1'-ethoxycarbonyloxyethyl ester of benzylpenicillin

Also Published As

Publication number Publication date
YU141583A (en) 1986-06-30
GB2169287A (en) 1986-07-09
CY1520A (en) 1990-11-16
YU43926B (en) 1989-12-31
YU21886A (en) 1987-10-31
GB2168050A (en) 1986-06-11
AU1632883A (en) 1984-01-05
IS2825A7 (en) 1984-07-08
PT76944A (en) 1983-07-01
FR2543957B1 (en) 1986-10-24
SE9100548L (en) 1991-02-26
DK160039C (en) 1991-06-10
FI79115C (en) 1989-11-10
YU43693B (en) 1989-10-31
GB8522826D0 (en) 1985-10-23
JPH0730082B2 (en) 1995-04-05
JPH0717918A (en) 1995-01-20
AU566803B2 (en) 1987-10-29
DD211561A5 (en) 1984-07-18
IL68992A (en) 1991-06-10
BG38335A3 (en) 1985-11-15
GB2169287B (en) 1987-04-08
JPH0543583A (en) 1993-02-23
SE454879B (en) 1988-06-06
CH657620B (en) 1986-09-15
FI79115B (en) 1989-07-31
DK167807B1 (en) 1993-12-20
DK159821B (en) 1990-12-10
BG38336A3 (en) 1985-11-15
NO851255L (en) 1983-12-30
CY1519A (en) 1990-11-16
DE3348299C2 (en) 1990-12-20
NZ204736A (en) 1986-11-12
SE503843C2 (en) 1996-09-16
NL8302286A (en) 1984-01-16
FI832363A0 (en) 1983-06-28
FR2543957A1 (en) 1984-10-12
IS1361B6 (en) 1989-05-25
NO832351L (en) 1983-12-30
GR78585B (en) 1984-09-27
PT76944B (en) 1986-04-09
NO157696C (en) 1988-05-04
IE56712B1 (en) 1991-11-20
SE9100548D0 (en) 1991-02-26
DE3322783A1 (en) 1984-02-09
FI832363L (en) 1983-12-30
DK159821C (en) 1991-04-29
DE3322783C2 (en) 1991-01-31
GB8528958D0 (en) 1986-01-02
GB2168699A (en) 1986-06-25
DK160039B (en) 1991-01-21
DK296683A (en) 1983-12-30
HU191534B (en) 1987-03-30
ATA238483A (en) 1986-10-15
SE8303414L (en) 1983-12-30
DK105990A (en) 1990-04-30
NO851254L (en) 1983-12-30
CH656377A5 (en) 1986-06-30
JPH0819052B2 (en) 1996-02-28
DK296683D0 (en) 1983-06-28
AT383128B (en) 1987-05-25
IE831445L (en) 1983-12-29
NO157696B (en) 1988-01-25
DK106090D0 (en) 1990-04-30
GB8522827D0 (en) 1985-10-23
NL194081B (en) 2001-02-01
NL194081C (en) 2001-06-05
DK105990D0 (en) 1990-04-30
DK106090A (en) 1990-04-30
SE8303414D0 (en) 1983-06-15
BG37527A3 (en) 1985-06-14

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years