NO157696B - ALFA-BROMDETHYL CARBONATE AND PROCEDURE FOR ITS PREPARATION. - Google Patents

ALFA-BROMDETHYL CARBONATE AND PROCEDURE FOR ITS PREPARATION. Download PDF

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Publication number
NO157696B
NO157696B NO832351A NO832351A NO157696B NO 157696 B NO157696 B NO 157696B NO 832351 A NO832351 A NO 832351A NO 832351 A NO832351 A NO 832351A NO 157696 B NO157696 B NO 157696B
Authority
NO
Norway
Prior art keywords
mass
preparation
dry
substrate
cement
Prior art date
Application number
NO832351A
Other languages
Norwegian (no)
Other versions
NO832351L (en
NO157696C (en
Inventor
Luigi Ratti
Derek Reginald Palmer
Robert Graham Tyson
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT22141/82A external-priority patent/IT1190897B/en
Priority claimed from GB838300331A external-priority patent/GB8300331D0/en
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of NO832351L publication Critical patent/NO832351L/en
Priority to NO841350A priority Critical patent/NO159093C/en
Priority to NO871808A priority patent/NO161858C/en
Publication of NO157696B publication Critical patent/NO157696B/en
Publication of NO157696C publication Critical patent/NO157696C/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00Preparation of esters of carbonic or haloformic acids
    • C07C68/02Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96Esters of carbonic or haloformic acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

Den nye forbindelsen a-bromdietylkarbonat,. nye fremgangsmåter for fremstilling av denne forbindelsen, dens anvendelse under fremstillingen av 1-etylkarbonyloksyetylestere av penicilliner og cefalosporiner samt forbedringer i fremgangsmåten for fremstilling av slike estere.The new compound α-bromodiethyl carbonate ,. new processes for the preparation of this compound, its use in the preparation of 1-ethylcarbonyloxyethyl esters of penicillins and cephalosporins and improvements in the process for the preparation of such esters.

Description

Fremgangsmåte til fremstilling av en trinnlyd-dempende varmeisolerende masse, som er egnet som underlag for gulv. Process for the production of a step sound-absorbing heat-insulating mass, which is suitable as a substrate for floors.

I det svenske patent nr. 114 915 beskrives et In the Swedish patent no. 114 915, a

fyllstoffmateriale av vegetabilsk opprinnelse beregnet til å brukes ved fremstilling av bygnings-materiale med hydrauliske bindemidler eller filler material of vegetable origin intended for use in the production of building material with hydraulic binders or

kalk. Ifølge dette patent lagres det vegetabilske lime. According to this patent, the vegetable is stored

materialet i så lang tid og under slike forhold, the material for such a long time and under such conditions,

at det inntrer såkalt selvbrenning, hvoretter det that so-called spontaneous combustion occurs, after which it

tilsettes en mindre mengde tørt, hydraulisk bindemiddel eller kalk samtidig som man sørger for a small amount of dry, hydraulic binder or lime is added at the same time as care is taken

at materialet pmrøres. Den tilsatte mengde hydraulisk bindemiddel, som bare utgjør 1 og 2 that the material is stirred. The added amount of hydraulic binder, which only makes up 1 and 2

volumpst. av det vegetabilske materialet, er så volume of the vegetable material, is so

liten at massen ikke kan herdne uten bestandig small that the mass cannot harden without constant

å komme til å foreligge i kornet form. Grunnen to come to be in granular form. Reason

til at sementtilsetningen må holdes innen snevre so that the cement addition must be kept within a narrow range

grenser er den temperaturøkning som frembrin-ges av en større tilsetning, med etterfølgende limits are the temperature increase produced by a larger addition, with subsequent

tørkning og tilstopping av det vegetabilske materialets celler, hvorved beregnet luftoksydasjon drying and clogging of the cells of the vegetable material, whereby air oxidation is calculated

av kullhydrater og lignende skulle bli vanskelig-gjort. of carbohydrates and the like would be made difficult.

Det er av den største betydning at under-lagsmasser for gulvplater, linoleum på trefiber-plater, parkettmateriale, gulvbord og lignende i tørt, kornet og uforanderlig stand, således uten tilsetning av cement eller andre bindemidler og' vann, har slike egenskaper at gulvbelegget, ved belastning bare i ubetydelig grad synker med i massen. Videre at den lett fyller ut underlagets ujevnheter for å unngå lydledende såkalt bom-partier, samt at det oppnås en fullstendig plan og fullt ferdig overflate for plassering av det ferdige gulv, bare ved oppretting med rettholdt eller lignende på vanlig måte. Et materiale av denne art, som beskrives i svensk patent nr. 114 915 fyller ikke de nødvendige krav, hverken når det gjelder pakningsgrad eller struktur. It is of the greatest importance that underlays for floorboards, linoleum on wood fiber boards, parquet material, floorboards and the like in a dry, grained and unchanging state, thus without the addition of cement or other binders and water, have such properties that the floor covering, under load only to an insignificant extent sinks with the mass. Furthermore, that it easily fills in the unevenness of the substrate to avoid sound-conducting so-called boom sections, and that a completely level and completely finished surface is achieved for the placement of the finished floor, only by straightening it with straight held or similar in the usual way. A material of this kind, which is described in Swedish patent no. 114 915, does not fulfill the necessary requirements, either in terms of packing degree or structure.

Foreliggende oppfinnelse angår en fremgangsmåte til fremstilling av en som underlag for gulv beregnet, trinnlyd-dempende og varmeisolerende masse av det ovenfor beskrevne fyll-stoff og karakteristisk for oppfinnelsen er at for oppnåelse av volumvekt, redusert pakningsgrad og elastisitet til dette materialet settes et hydraulisk bindemiddel, så som cement, i en mengde av 50—200 gram pr. liter vegetabilsk materiale, og at det fremstilles en masse som får herde og tørke og deretter knuses til en korn-størrelse som er mindre enn 5 mm for siden i tørr tilstand å legges ut som underlag. The present invention relates to a method for the production of a footfall sound-absorbing and heat-insulating mass of the above-described filler intended as a substrate for floors, and a characteristic of the invention is that in order to achieve volume weight, reduced degree of packing and elasticity, a hydraulic binder is added to this material , such as cement, in an amount of 50-200 grams per liter of vegetable material, and that a mass is produced which is allowed to harden and dry and then crushed to a grain size of less than 5 mm for the side in a dry state to be laid out as a substrate.

Det hydrauliske bindemiddel skal være av en slik beskaffenhet at det kan blandes intimt med det vegetabilske, for-behandlede materialet og skal dessuten ha en slik finhetsgrad at det ved innblanding trenger inn i det vegetabilske materialets celler. Det bør også ha en viss grad av vedheftingsevne, slik at separering forhind-res, og at det ved innblanding fordeler seg j evnt mellom de forskjellige vegetabilske partikler. The hydraulic binder must be of such a nature that it can be mixed intimately with the vegetable, pre-treated material and must also have such a degree of fineness that it penetrates into the cells of the vegetable material when mixed. It should also have a certain degree of adhesion, so that separation is prevented, and that when mixed in it distributes evenly between the different vegetable particles.

Det har således vist seg hensiktsmessig å øke volumvekten på materialet med ca. 80 til 200 g, fortrinnsvis 100—150 g regnet pr. liter vegetabilsk materiale med en fuktprosent på ca. 20. It has thus proved appropriate to increase the volume weight of the material by approx. 80 to 200 g, preferably 100-150 g calculated per liter of vegetable material with a moisture percentage of approx. 20.

Eksempel. Example.

Sagspon, som er behandlet ifølge svensk patent nr. 114 915, tilsettes portlandcement i en mengde på 100 g cement pr. liter sagspon. Den på denne måte oppnådde blanding lagres, inntil cementen er herdet og deretter knuses det hele og siktes til sagsponets opprinnelige kornstør-relse. Deretter tørkes materiale til en hensiktsmessig fuktighet, f. eks. ca. 12 volumpst. Massen har ved denne behandling fått et tilskudd av meget finkornet, herdet cement, som gir massen den ønskede økte volumvekten og hensiktsmes-sigefe struktur og som vanskeliggjør separering av massens bestanddeler. Sawdust, which has been treated according to Swedish patent no. 114 915, is added to Portland cement in a quantity of 100 g of cement per liters of sawdust. The mixture obtained in this way is stored until the cement has hardened and then the whole is crushed and sieved to the sawdust's original grain size. The material is then dried to an appropriate humidity, e.g. about. 12 volume units During this treatment, the mass has received an addition of very fine-grained, hardened cement, which gives the mass the desired increased volume weight and suitable structure and which makes it difficult to separate the components of the mass.

Vekten kan riktignok økes ved tilsetning av The weight can, of course, be increased by adding

f. eks. sand, men også i meget fin kornet form separerer den lett fra et vegetabilsk materiale av denne art, spesielt dersom det er tørt. e.g. sand, but also in very fine grained form, it separates easily from a vegetable material of this kind, especially if it is dry.

Ved gulvlegging utlegges den ovenfor beskrevne masse på et betongbjelkelag, der den utbres og avrettes med såkalt rettholt til en lag-tykkelse på ca. 3 cm, slik at det oppnås en fullstendig plan flate. På denne flate legges deretter betongplater på ca. 4 cm tykkelse og en flate-størrelse på 50 ganger 50 cm. Platene kan enten plasseres tett inntil hverandre eller med mel-lomrom som utfylles med cementmørtel. På grunn av den reduserte pakningsgraden i massen, nedtrenger platen ubetydelig av egen tyngde og beholder deretter sin stilling også ved ytter-ligere belastning. Gulvet er nå ferdig og fyller deretter som undergulv med bred margin de offisielle fordringer på trinnlydisolering i bo-stedshus, altså uten belegg av linoleum, parkett eller lignende. When laying the floor, the mass described above is laid out on a layer of concrete beams, where it is spread out and leveled with so-called straight timber to a layer thickness of approx. 3 cm, so that a completely flat surface is achieved. Concrete slabs of approx. 4 cm thick and a surface size of 50 by 50 cm. The boards can either be placed close to each other or with gaps that are filled with cement mortar. Due to the reduced degree of packing in the mass, the plate sinks down insignificantly under its own weight and then retains its position even under additional load. The floor is now finished and, as a subfloor, fulfills by a wide margin the official requirements for footfall sound insulation in residential buildings, i.e. without coverings of linoleum, parquet or the like.

Claims (1)

Fremgangsmåte til fremstilling av en varmeisolerende og trinnlyd-dempende masse av vegetabilsk materiale, så som sagspon, for underlag for gulv, hvilken masse er lagret under slike forhold at såkéalt selvbrenning inntrer, idet det under denne lagring er tilsatt en mindre mengde tørt, hydraulisk bindemiddel eller kalk under omrøring av materialet, karakterisert ved at denne forbehandlede masse tilsettes et hydraulisk bindemiddel, såsom cement, i en mengde av 50—200 g pr. litsr vegetabilsk materiale, og at det beredes en masse som får herde og tørke og deretter knuses til en korn-størrelse som er mindre enn ca. 5 mm, for deretter i tørr tilstand å utlegges som underlag.Process for the production of a heat-insulating and step-sound dampening mass of vegetable material, such as sawdust, for a substrate for floors, which mass is stored under such conditions that spontaneous combustion occurs, as a small amount of dry, hydraulic binder is added during this storage or lime while stirring the material, characterized in that a hydraulic binder, such as cement, is added to this pre-treated mass in an amount of 50-200 g per litsr vegetable material, and that a mass is prepared which is allowed to harden and dry and then crushed to a grain size smaller than approx. 5 mm, then in a dry state to be laid out as a substrate.
NO832351A 1982-06-29 1983-06-28 AAA-BROMDETHYL CARBONATE AND PROCEDURE FOR ITS PREPARATION. NO157696C (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
NO841350A NO159093C (en) 1982-06-29 1984-04-05 PROCEDURE FOR PREPARING THE 1-ETHOXYCARBONYLOXYTHYL ESTE OF 6- (D - (-) - ALFA-AMINO-ALFA-PHENYLACETAMIDO) -PENICILLANIC ACID (BACAMPICILLIN).
NO871808A NO161858C (en) 1982-06-29 1987-04-30 PROCEDURE FOR PREPARING THE 1-ETHOXY CARBONYLOXYETHYL ESTE OF PENICILLIN G.

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IT22141/82A IT1190897B (en) 1982-06-29 1982-06-29 PROCEDURE FOR THE PREPARATION OF THE 1-ETHOXYCARBONYLOXYETHYL ACID ACID 6- (D (-) - ALPHA AMINOALPHA-PHENYLACETAMIDE) -PENICILLANIC
GB8226751 1982-09-20
GB8228622 1982-10-06
GB8232629 1982-11-16
GB838300331A GB8300331D0 (en) 1983-01-07 1983-01-07 Preparation of bromo carbonates

Publications (3)

Publication Number Publication Date
NO832351L NO832351L (en) 1983-12-30
NO157696B true NO157696B (en) 1988-01-25
NO157696C NO157696C (en) 1988-05-04

Family

ID=27516485

Family Applications (3)

Application Number Title Priority Date Filing Date
NO832351A NO157696C (en) 1982-06-29 1983-06-28 AAA-BROMDETHYL CARBONATE AND PROCEDURE FOR ITS PREPARATION.
NO851255A NO851255L (en) 1982-06-29 1985-03-28 PROCEDURE FOR THE PREPARATION OF ETHOXYCARBONLOXY ETHYL ESTER OF 6-AMINOPENICILLINES AND CEPHALOSPORINES
NO851254A NO851254L (en) 1982-06-29 1985-03-28 PROCEDURE FOR PREPARING THE 1-ETHOXYCARBONLOXY ETHYL ESTER OF 6- (D - (-) - ALFA-AMINO-ALFA-PHENYLACETAMIDO) PENICILLANIC ACID

Family Applications After (2)

Application Number Title Priority Date Filing Date
NO851255A NO851255L (en) 1982-06-29 1985-03-28 PROCEDURE FOR THE PREPARATION OF ETHOXYCARBONLOXY ETHYL ESTER OF 6-AMINOPENICILLINES AND CEPHALOSPORINES
NO851254A NO851254L (en) 1982-06-29 1985-03-28 PROCEDURE FOR PREPARING THE 1-ETHOXYCARBONLOXY ETHYL ESTER OF 6- (D - (-) - ALFA-AMINO-ALFA-PHENYLACETAMIDO) PENICILLANIC ACID

Country Status (23)

Country Link
JP (2) JPH0819052B2 (en)
AT (1) AT383128B (en)
AU (1) AU566803B2 (en)
BG (3) BG38336A3 (en)
CH (2) CH657620B (en)
CY (2) CY1520A (en)
DD (1) DD211561A5 (en)
DE (2) DE3348299C2 (en)
DK (3) DK160039C (en)
FI (1) FI79115C (en)
FR (1) FR2543957B1 (en)
GB (3) GB2168050A (en)
GR (1) GR78585B (en)
HU (1) HU191534B (en)
IE (1) IE56712B1 (en)
IL (1) IL68992A (en)
IS (1) IS1361B6 (en)
NL (1) NL194081C (en)
NO (3) NO157696C (en)
NZ (1) NZ204736A (en)
PT (1) PT76944B (en)
SE (2) SE454879B (en)
YU (2) YU43926B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2573756B1 (en) * 1984-11-23 1987-01-16 Poudres & Explosifs Ste Nale PROCESS FOR THE PREPARATION OF BROMO-1 ETHYL AND HYDROCARBYL CARBONATES AND NOVEL BROMO-1 ETHYL AND HYDROCARBYL CARBONATES

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH516593A (en) * 1967-09-29 1971-12-15 Leo Pharm Prod Ltd Alpha amino-benzyl penicillins - useful as oral antibiotics
US3873521A (en) * 1970-09-17 1975-03-25 Astra Laekemedel Ab Esters of {60 -amino penicillins
IE35648B1 (en) * 1970-09-25 1976-04-14 Beecham Group Ltd Penicillins
DE2161420A1 (en) * 1970-12-30 1972-07-27 Toyama Chemical Co. Ltd., Tokio Penicillin derivatives and processes for their preparation
BE784800A (en) * 1971-06-15 1972-10-02 Yamanouchi Pharma Co Ltd PROCESS FOR PREPARING NEW OXYMETHYL ESTERS OF PENICILLIN AND CEPHALOSPORIN
IL41313A (en) * 1972-02-15 1976-08-31 Harrison Ltd Preparation of the lh-and fsh-releasing hormone and compositions containing it
GB1426869A (en) * 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
GB1425571A (en) * 1972-03-13 1976-02-18 Astra Laekemedel Ab Penicillins and cephaosporins
GB1426717A (en) * 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
SE397981B (en) * 1973-02-19 1977-11-28 Astra Laekemedel Ab NEW TETRAALKYLAMMONIUM SALTS OF 6-AMINOPENICILLANIC ACID AND OF BENZYLPENICILLIN INTENDED TO BE USED AS INTERMEDIATE PRODUCTS IN THE PREPARATION OF CERTAIN ESTERS OF 6-AMINOPENICILLANIC ACID AND OF BENZYLPENIC
GB1565656A (en) * 1975-12-13 1980-04-23 Beecham Group Ltd Preparation of substituted penicillin acid esters
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
JPS5444694A (en) * 1977-09-06 1979-04-09 Kou Kamata Aminobenzylpenicillin derivative
LU84887A1 (en) * 1982-06-30 1984-03-07 Glaxo Group Ltd ANTIBIOTICS OF THE NATURE OF CEPHALOSPORINS AND THEIR PREPARATION PROCESS
EP0108547B1 (en) * 1982-11-04 1989-06-07 Astra Lakemedel Aktiebolag Process for the preparation of the 1'-ethoxycarbonyloxyethyl ester of benzylpenicillin

Also Published As

Publication number Publication date
CH656377A5 (en) 1986-06-30
SE8303414D0 (en) 1983-06-15
FI79115C (en) 1989-11-10
CH657620B (en) 1986-09-15
NL194081C (en) 2001-06-05
DK105990D0 (en) 1990-04-30
JPH0543583A (en) 1993-02-23
SE454879B (en) 1988-06-06
NL194081B (en) 2001-02-01
DK167807B1 (en) 1993-12-20
CY1520A (en) 1990-11-16
DK106090A (en) 1990-04-30
NZ204736A (en) 1986-11-12
YU21886A (en) 1987-10-31
GB2169287B (en) 1987-04-08
BG38336A3 (en) 1985-11-15
YU43693B (en) 1989-10-31
DK159821B (en) 1990-12-10
HU191534B (en) 1987-03-30
AU566803B2 (en) 1987-10-29
SE9100548L (en) 1991-02-26
FI79115B (en) 1989-07-31
AT383128B (en) 1987-05-25
DK105990A (en) 1990-04-30
DK106090D0 (en) 1990-04-30
CY1519A (en) 1990-11-16
JPH0717918A (en) 1995-01-20
NO832351L (en) 1983-12-30
SE503843C2 (en) 1996-09-16
PT76944B (en) 1986-04-09
IS1361B6 (en) 1989-05-25
IE831445L (en) 1983-12-29
JPH0819052B2 (en) 1996-02-28
FI832363L (en) 1983-12-30
GB2168050A (en) 1986-06-11
PT76944A (en) 1983-07-01
GR78585B (en) 1984-09-27
GB2169287A (en) 1986-07-09
DE3348299C2 (en) 1990-12-20
NO851255L (en) 1983-12-30
NO851254L (en) 1983-12-30
DK159821C (en) 1991-04-29
DE3322783A1 (en) 1984-02-09
BG37527A3 (en) 1985-06-14
NL8302286A (en) 1984-01-16
DK160039B (en) 1991-01-21
AU1632883A (en) 1984-01-05
GB2168699A (en) 1986-06-25
NO157696C (en) 1988-05-04
FI832363A0 (en) 1983-06-28
YU43926B (en) 1989-12-31
JPH0730082B2 (en) 1995-04-05
YU141583A (en) 1986-06-30
FR2543957B1 (en) 1986-10-24
SE8303414L (en) 1983-12-30
IS2825A7 (en) 1984-07-08
GB2168699B (en) 1987-04-15
BG38335A3 (en) 1985-11-15
GB8522827D0 (en) 1985-10-23
SE9100548D0 (en) 1991-02-26
IE56712B1 (en) 1991-11-20
DD211561A5 (en) 1984-07-18
ATA238483A (en) 1986-10-15
DK296683D0 (en) 1983-06-28
GB8522826D0 (en) 1985-10-23
DE3322783C2 (en) 1991-01-31
FR2543957A1 (en) 1984-10-12
IL68992A (en) 1991-06-10
GB8528958D0 (en) 1986-01-02
DK160039C (en) 1991-06-10
DK296683A (en) 1983-12-30

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