JPH0730082B2 - バカンピシリンの新規な製造法 - Google Patents

バカンピシリンの新規な製造法

Info

Publication number
JPH0730082B2
JPH0730082B2 JP3124441A JP12444191A JPH0730082B2 JP H0730082 B2 JPH0730082 B2 JP H0730082B2 JP 3124441 A JP3124441 A JP 3124441A JP 12444191 A JP12444191 A JP 12444191A JP H0730082 B2 JPH0730082 B2 JP H0730082B2
Authority
JP
Japan
Prior art keywords
formula
ampicillin
group
reaction
enamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP3124441A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0543583A (ja
Inventor
ルイジ・ラツテイ
デレク・レジナルド・パーマー
ロバート・グレイアム・タイソン
Original Assignee
アストラ・レーケメデル・アクチエボラーグ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT22141/82A external-priority patent/IT1190897B/it
Priority claimed from GB838300331A external-priority patent/GB8300331D0/en
Application filed by アストラ・レーケメデル・アクチエボラーグ filed Critical アストラ・レーケメデル・アクチエボラーグ
Publication of JPH0543583A publication Critical patent/JPH0543583A/ja
Publication of JPH0730082B2 publication Critical patent/JPH0730082B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00—Preparation of esters of carbonic or haloformic acids
    • C07C68/02—Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96—Esters of carbonic or haloformic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP3124441A 1982-06-29 1991-04-30 バカンピシリンの新規な製造法 Expired - Lifetime JPH0730082B2 (ja)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
IT22141/82A IT1190897B (it) 1982-06-29 1982-06-29 Procedimento per la preparazione dell'estere 1-etossicarbonilossietilico dell'acido 6-(d(-)-alfa aminoalfa fenilacetamido)-penicillanico
GB8226751 1982-09-20
GB8226751 1982-09-20
GB8228622 1982-10-06
GB8228622 1982-10-06
GB8232629 1982-11-16
GB8232629 1982-11-16
GB8300331 1983-01-07
GB22141-A/82 1983-01-07
GB838300331A GB8300331D0 (en) 1983-01-07 1983-01-07 Preparation of bromo carbonates

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP58114465A Division JPS5920287A (ja) 1982-06-29 1983-06-27 バカンピシリンの新規な製造法

Publications (2)

Publication Number Publication Date
JPH0543583A JPH0543583A (ja) 1993-02-23
JPH0730082B2 true JPH0730082B2 (ja) 1995-04-05

Family

ID=27516485

Family Applications (2)

Application Number Title Priority Date Filing Date
JP3124441A Expired - Lifetime JPH0730082B2 (ja) 1982-06-29 1991-04-30 バカンピシリンの新規な製造法
JP3124442A Expired - Lifetime JPH0819052B2 (ja) 1982-06-29 1991-04-30 α−ブロモジエチルカーボネート

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP3124442A Expired - Lifetime JPH0819052B2 (ja) 1982-06-29 1991-04-30 α−ブロモジエチルカーボネート

Country Status (23)

Country Link
JP (2) JPH0730082B2 (no)
AT (1) AT383128B (no)
AU (1) AU566803B2 (no)
BG (3) BG38336A3 (no)
CH (2) CH657620B (no)
CY (2) CY1519A (no)
DD (1) DD211561A5 (no)
DE (2) DE3322783A1 (no)
DK (3) DK160039C (no)
FI (1) FI79115C (no)
FR (1) FR2543957B1 (no)
GB (3) GB2168050A (no)
GR (1) GR78585B (no)
HU (1) HU191534B (no)
IE (1) IE56712B1 (no)
IL (1) IL68992A (no)
IS (1) IS1361B6 (no)
NL (1) NL194081C (no)
NO (3) NO157696C (no)
NZ (1) NZ204736A (no)
PT (1) PT76944B (no)
SE (2) SE454879B (no)
YU (2) YU43926B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2573756B1 (fr) * 1984-11-23 1987-01-16 Poudres & Explosifs Ste Nale Procede de preparation des carbonates de bromo-1 ethyle et d'hydrocarbyle et nouveaux carbonates de bromo-1 ethyle et d'hydrocarbyle

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH516593A (de) * 1967-09-29 1971-12-15 Leo Pharm Prod Ltd Verfahren zur Herstellung von neuen Estern von a-Aminobenzyl-penicillin
US3873521A (en) * 1970-09-17 1975-03-25 Astra Laekemedel Ab Esters of {60 -amino penicillins
IE35648B1 (en) * 1970-09-25 1976-04-14 Beecham Group Ltd Penicillins
DE2161420A1 (de) * 1970-12-30 1972-07-27 Toyama Chemical Co. Ltd., Tokio Penicillinderivate und Verfahren zu deren Herstellung
DE2228670A1 (de) * 1971-06-15 1973-01-11 Yamanouchi Pharma Co Ltd Neue oxymethylesterderivate von penicillin und cephalosporin
NZ169577A (en) * 1972-02-15 1984-09-28 Ayerst Mckenna & Harrison Preparation of lh-and fsh-releasing hormone,intermediates,and pharmaceutical compositions
GB1425571A (en) * 1972-03-13 1976-02-18 Astra Laekemedel Ab Penicillins and cephaosporins
GB1426717A (en) * 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
GB1426869A (en) * 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
SE397981B (sv) * 1973-02-19 1977-11-28 Astra Laekemedel Ab Nya tetraalkylammoniumsalter av 6-aminopenicillansyra och av bensylpenicillin avsedda att anvendas som mellanprodukter vid framstellning av vissa estrar av 6-aminopenicillansyra och av bensylpenicillin
GB1565656A (en) * 1975-12-13 1980-04-23 Beecham Group Ltd Preparation of substituted penicillin acid esters
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
JPS5444694A (en) * 1977-09-06 1979-04-09 Kou Kamata Aminobenzylpenicillin derivative
NO832376L (no) * 1982-06-30 1984-01-02 Glaxo Group Ltd Cephalosporin-antibiotika.
ATE43833T1 (de) * 1982-11-04 1989-06-15 Astra Laekemedel Ab Verfahren zur herstellung des 1'ethoxycarbonyloxyethylestersvon benzylpenicillin.

Also Published As

Publication number Publication date
DK296683A (da) 1983-12-30
GB8528958D0 (en) 1986-01-02
FI79115B (fi) 1989-07-31
BG38335A3 (en) 1985-11-15
YU141583A (en) 1986-06-30
ATA238483A (de) 1986-10-15
DK106090A (da) 1990-04-30
GB2169287A (en) 1986-07-09
NL194081C (nl) 2001-06-05
AU566803B2 (en) 1987-10-29
DE3322783A1 (de) 1984-02-09
JPH0819052B2 (ja) 1996-02-28
DK167807B1 (da) 1993-12-20
JPH0543583A (ja) 1993-02-23
SE454879B (sv) 1988-06-06
DK159821B (da) 1990-12-10
GB8522827D0 (en) 1985-10-23
YU43693B (en) 1989-10-31
CH657620B (no) 1986-09-15
IS1361B6 (is) 1989-05-25
FI832363A0 (fi) 1983-06-28
DK105990A (da) 1990-04-30
FR2543957B1 (fr) 1986-10-24
DD211561A5 (de) 1984-07-18
NO851255L (no) 1983-12-30
DE3348299C2 (no) 1990-12-20
GB2168050A (en) 1986-06-11
YU43926B (en) 1989-12-31
FR2543957A1 (fr) 1984-10-12
YU21886A (en) 1987-10-31
DK105990D0 (da) 1990-04-30
FI832363L (fi) 1983-12-30
DK160039C (da) 1991-06-10
GB8522826D0 (en) 1985-10-23
CY1520A (en) 1990-11-16
CY1519A (en) 1990-11-16
NO157696C (no) 1988-05-04
GB2168699A (en) 1986-06-25
GR78585B (no) 1984-09-27
SE9100548D0 (sv) 1991-02-26
NO851254L (no) 1983-12-30
GB2168699B (en) 1987-04-15
NO157696B (no) 1988-01-25
SE503843C2 (sv) 1996-09-16
NZ204736A (en) 1986-11-12
AT383128B (de) 1987-05-25
BG38336A3 (en) 1985-11-15
CH656377A5 (de) 1986-06-30
PT76944B (en) 1986-04-09
BG37527A3 (en) 1985-06-14
IE831445L (en) 1983-12-29
PT76944A (en) 1983-07-01
SE8303414D0 (sv) 1983-06-15
IS2825A7 (is) 1984-07-08
GB2169287B (en) 1987-04-08
SE8303414L (sv) 1983-12-30
DK160039B (da) 1991-01-21
DK106090D0 (da) 1990-04-30
JPH0717918A (ja) 1995-01-20
DE3322783C2 (no) 1991-01-31
DK159821C (da) 1991-04-29
DK296683D0 (da) 1983-06-28
IL68992A (en) 1991-06-10
NO832351L (no) 1983-12-30
NL8302286A (nl) 1984-01-16
HU191534B (en) 1987-03-30
AU1632883A (en) 1984-01-05
FI79115C (fi) 1989-11-10
IE56712B1 (en) 1991-11-20
NL194081B (nl) 2001-02-01
SE9100548L (sv) 1991-02-26

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