FI78291C - Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-fenoxi-3-hydroxi-indolyl-alkylamino-3-propanoler. - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-fenoxi-3-hydroxi-indolyl-alkylamino-3-propanoler. Download PDF

Info

Publication number
FI78291C
FI78291C FI842316A FI842316A FI78291C FI 78291 C FI78291 C FI 78291C FI 842316 A FI842316 A FI 842316A FI 842316 A FI842316 A FI 842316A FI 78291 C FI78291 C FI 78291C
Authority
FI
Finland
Prior art keywords
hydroxy
formula
iii
reaction
compounds
Prior art date
Application number
FI842316A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI842316A (fi
FI78291B (fi
FI842316A0 (fi
Inventor
William E Kreighbaum
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI842316A0 publication Critical patent/FI842316A0/fi
Publication of FI842316A publication Critical patent/FI842316A/fi
Application granted granted Critical
Publication of FI78291B publication Critical patent/FI78291B/fi
Publication of FI78291C publication Critical patent/FI78291C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI842316A 1983-06-10 1984-06-07 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-fenoxi-3-hydroxi-indolyl-alkylamino-3-propanoler. FI78291C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50290183A 1983-06-10 1983-06-10
US50290183 1983-06-10

Publications (4)

Publication Number Publication Date
FI842316A0 FI842316A0 (fi) 1984-06-07
FI842316A FI842316A (fi) 1984-12-11
FI78291B FI78291B (fi) 1989-03-31
FI78291C true FI78291C (fi) 1989-07-10

Family

ID=23999880

Family Applications (1)

Application Number Title Priority Date Filing Date
FI842316A FI78291C (fi) 1983-06-10 1984-06-07 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-fenoxi-3-hydroxi-indolyl-alkylamino-3-propanoler.

Country Status (29)

Country Link
JP (1) JPS608262A (fr)
KR (1) KR900005021B1 (fr)
AT (1) AT381492B (fr)
AU (1) AU569303B2 (fr)
BE (1) BE899875A (fr)
CA (1) CA1217496A (fr)
CH (1) CH662561A5 (fr)
CY (1) CY1518A (fr)
DE (1) DE3421252A1 (fr)
DK (1) DK162089C (fr)
ES (1) ES533185A0 (fr)
FI (1) FI78291C (fr)
FR (1) FR2549054B1 (fr)
GB (1) GB2141121B (fr)
GR (1) GR82208B (fr)
HK (1) HK14690A (fr)
HU (1) HU191670B (fr)
IE (1) IE57682B1 (fr)
IL (1) IL72008A (fr)
IT (1) IT1206705B (fr)
LU (1) LU85410A1 (fr)
MY (1) MY102077A (fr)
NL (1) NL8401840A (fr)
NO (1) NO164471C (fr)
NZ (1) NZ208337A (fr)
SE (1) SE455865B (fr)
SG (1) SG1090G (fr)
YU (1) YU44873B (fr)
ZA (1) ZA844277B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601008B1 (fr) * 1986-07-03 1990-03-30 Sanofi Sa Procede de synthese stereospecifique de derives de l'indole
KR101986648B1 (ko) 2018-04-06 2019-06-07 (유)로뎀건설 강관작업구 굴착장치

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES259580A1 (es) * 1959-07-13 1961-01-16 Philips Nv Procedimiento para la preparacion de nuevas indolietilaminas farmacologicamente activas
NL300886A (fr) * 1962-11-23
US4234595A (en) * 1977-07-13 1980-11-18 Mead Johnson & Company 3-Indolyl-tertiary butylaminopropanols
CA1116598A (fr) * 1977-07-13 1982-01-19 William T. Comer 3-indolyl-butylaminopropanols tertiaires
US4314943A (en) * 1977-07-13 1982-02-09 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire

Also Published As

Publication number Publication date
NO164471B (no) 1990-07-02
ES8507490A1 (es) 1985-09-16
DK162089C (da) 1992-02-24
GB2141121B (en) 1987-01-07
BE899875A (fr) 1984-12-10
GB8414652D0 (en) 1984-07-11
FR2549054B1 (fr) 1988-03-04
CH662561A5 (de) 1987-10-15
YU99784A (en) 1986-10-31
HUT34445A (en) 1985-03-28
KR850000396A (ko) 1985-02-27
IE841441L (en) 1984-12-10
LU85410A1 (fr) 1985-03-26
MY102077A (en) 1992-03-31
KR900005021B1 (ko) 1990-07-18
YU44873B (en) 1991-04-30
ZA844277B (en) 1985-03-27
DE3421252A1 (de) 1984-12-13
AU2923884A (en) 1984-12-13
JPH0587503B2 (fr) 1993-12-16
NO164471C (no) 1990-10-10
FI842316A (fi) 1984-12-11
SE8403112D0 (sv) 1984-06-08
ATA186784A (de) 1986-03-15
GR82208B (fr) 1984-12-13
FI78291B (fi) 1989-03-31
ES533185A0 (es) 1985-09-16
SE455865B (sv) 1988-08-15
IL72008A (en) 1988-05-31
CA1217496A (fr) 1987-02-03
NZ208337A (en) 1988-10-28
SE8403112L (sv) 1984-12-11
AU569303B2 (en) 1988-01-28
HU191670B (en) 1987-03-30
AT381492B (de) 1986-10-27
IT8421330A0 (it) 1984-06-08
IE57682B1 (en) 1993-02-24
FI842316A0 (fi) 1984-06-07
FR2549054A1 (fr) 1985-01-18
DK162089B (da) 1991-09-16
DK284184D0 (da) 1984-06-08
NO842279L (no) 1984-12-11
IL72008A0 (en) 1984-10-31
NL8401840A (nl) 1985-01-02
JPS608262A (ja) 1985-01-17
DK284184A (da) 1984-12-11
SG1090G (en) 1990-07-06
IT1206705B (it) 1989-04-27
GB2141121A (en) 1984-12-12
HK14690A (en) 1990-03-02
CY1518A (en) 1990-11-16

Similar Documents

Publication Publication Date Title
EA005491B1 (ru) Способ получения циталопрама
FI78291C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-fenoxi-3-hydroxi-indolyl-alkylamino-3-propanoler.
EP0637307B1 (fr) Derives de l'imidazole, du triazole et du tetrazole
RU2067576C1 (ru) Производные 4-фенилметил-1н-индола в виде энантиомеров, рацематов или диастереоизомеров или в виде кислотно-аддитивных солей, обладающие антиаритмической или антикальциевой активностью
HU224435B1 (hu) Benzodiazepin-származékok, eljárás előállításukra, alkalmazásukra és ezeket tartalmazó gyógyászati készítmények
FI57747C (fi) Foerfarande foer framstaellning av nya isoindolin-1-on-derivat vilka aer anvaendbara saosom medel mot arytmi
FI85138C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-fenylpropylindolderivat.
EP0296048B1 (fr) Nouveaux dérivés de la pipérazinyl alkyl piperazine dione, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent
FI79709C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 1-pyridyloxi-2 eller 3-indolylalkylamino-2-propanolderivat.
US4292323A (en) Phenyl-1,2,3,4-tetrahydrocarbazoles and use thereof
FI77444B (fi) Foerfarande foer framstaellning av nya aminometyl-1h-indol-4-metanolderivat och deras salter.
EP1097136B1 (fr) Procede de preparation d'un derive d'indole
JPS6124395B2 (fr)
DK155280B (da) Analogifremgangsmaade til fremstilling af indolderivater
JPS5929063B2 (ja) 新規アリ−ルオキシアミノブタノ−ル誘導体の製法
CS247552B1 (en) 1-(2,4-dichlorophenoxy)-3-(3,4-dimethoxy-beta-phenethylamino)-2-propanol and its additional salts with acids
EP0746556A1 (fr) Composes tricycliques ayant une affinite pour le recepteur de 5-ht1a
GB2162523A (en) Intermediates for syntheses of indole derivatives

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: BRISTOL-MYERS CO