FI73666C - Foerfarande foer framstaellning av terapeutiskt aktiva 1-(dihydroxifenyl)-2-amino-etanolderivat och mellanprodukter foer framstaellning av dessa. - Google Patents
Foerfarande foer framstaellning av terapeutiskt aktiva 1-(dihydroxifenyl)-2-amino-etanolderivat och mellanprodukter foer framstaellning av dessa. Download PDFInfo
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- FI73666C FI73666C FI812158A FI812158A FI73666C FI 73666 C FI73666 C FI 73666C FI 812158 A FI812158 A FI 812158A FI 812158 A FI812158 A FI 812158A FI 73666 C FI73666 C FI 73666C
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Luminescent Compositions (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8022439 | 1980-07-09 | ||
| GB8022439 | 1980-07-09 | ||
| GB8116441 | 1981-05-29 | ||
| GB8116441 | 1981-05-29 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI812158L FI812158L (fi) | 1982-01-10 |
| FI73666B FI73666B (fi) | 1987-07-31 |
| FI73666C true FI73666C (fi) | 1987-11-09 |
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| FI812158A FI73666C (fi) | 1980-07-09 | 1981-07-08 | Foerfarande foer framstaellning av terapeutiskt aktiva 1-(dihydroxifenyl)-2-amino-etanolderivat och mellanprodukter foer framstaellning av dessa. |
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| US5830422A (en) * | 1995-06-23 | 1998-11-03 | Ormiston Mining And Smelting Co. Ltd. | Method for production of sodium bicarbonate, sodium carbonate and ammonium sulfate from sodium sulfate |
| CA2247953A1 (en) * | 1996-01-29 | 1997-07-31 | E. Charles Pesterfield Jr. | Method of treating undesired uterine contractions using optically pure r- or rr-isomers of adrenergic beta-2 agonists |
| SE9604752D0 (sv) * | 1996-12-20 | 1996-12-20 | Astra Ab | Formulation and use |
| KR20030085658A (ko) * | 2002-04-30 | 2003-11-07 | 한올제약주식회사 | 밤부테롤의 개선된 합성방법 |
| US7495028B2 (en) * | 2002-08-08 | 2009-02-24 | Wen Tan | R-bambuterol, its preparation and therapeutic uses |
| EP1542672B1 (en) * | 2002-08-08 | 2008-09-03 | Wen Tan | R-bambuterol, its preparation and therapeutic uses |
| EP1663999A2 (en) * | 2003-08-29 | 2006-06-07 | Ranbaxy Laboratories, Ltd. | Inhibitors of phosphodiesterase type-iv |
| EP1694655A2 (en) * | 2003-11-26 | 2006-08-30 | Ranbaxy Laboratories Limited | Phosphodiesterase inhibitors |
| WO2006081986A1 (en) * | 2005-02-07 | 2006-08-10 | F.Hoffmann-La Roche Ag | Bambuterol and integrin inhibitor combination |
| EP1934219A1 (en) | 2005-09-16 | 2008-06-25 | Ranbaxy Laboratories Limited | Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors |
| JP2009512677A (ja) * | 2005-10-19 | 2009-03-26 | ランバクシー ラボラトリーズ リミテッド | ホスホジエステラーゼタイプｉｖ阻害剤の組成物 |
| CA2626612A1 (en) | 2005-10-19 | 2007-04-26 | Ranbaxy Laboratories Limited | Pharmaceutical compositions of muscarinic receptor antagonists |
| BRPI0715231A2 (pt) | 2006-08-22 | 2013-06-25 | Ranbaxy Lab Ltd | compostos, composiÇÕes farmacÊuticas e seus usos, auxiliar quiral e seu uso e processos para preparar um composto |
| CN101616901A (zh) * | 2006-09-22 | 2009-12-30 | 兰贝克赛实验室有限公司 | Iv型磷酸二酯酶的抑制剂 |
| US20100029728A1 (en) * | 2006-09-22 | 2010-02-04 | Ranbaxy Laboratories Limited | Phosphodiesterase inhibitors |
| EP1958947A1 (en) | 2007-02-15 | 2008-08-20 | Ranbaxy Laboratories Limited | Inhibitors of phosphodiesterase type 4 |
| NZ579645A (en) | 2007-03-14 | 2012-01-12 | Ranbaxy Lab Ltd | Pyrazolo (3, 4-b) pyridine derivatives as phosphodiesterase inhibitors |
| WO2008111009A1 (en) * | 2007-03-14 | 2008-09-18 | Ranbaxy Laboratories Limited | Pyrazolo [3, 4-b] pyridine derivatives as phosphodiesterase inhibitors |
| EP2111861A1 (en) | 2008-04-21 | 2009-10-28 | Ranbaxy Laboratories Limited | Compositions of phosphodiesterase type IV inhibitors |
| PH12013500198A1 (en) | 2010-07-30 | 2013-03-11 | Ranbaxy Laboratories Ltd | Matrix metalloproteinase inhibitors |
| CA2812319A1 (en) | 2010-09-24 | 2012-03-29 | Ranbaxy Laboratories Limited | Matrix metalloproteinase inhibitors |
| CA2891234C (en) | 2012-12-03 | 2017-03-07 | Pfizer Inc. | Selective androgen receptor modulators |
| WO2014108449A1 (en) | 2013-01-08 | 2014-07-17 | Atrogi Ab | A screening method, a kit, a method of treatment and a compound for use in a method of treatment |
| CN104557614B (zh) * | 2014-12-15 | 2017-01-04 | 广东东阳光药业有限公司 | 一种胺的还原方法 |
| CN105622461B (zh) * | 2016-01-29 | 2018-06-19 | 华南理工大学 | 一种化合物及其制备方法与应用 |
| CN105859589B (zh) * | 2016-04-05 | 2018-09-28 | 深圳市康立生生物科技有限公司 | 一种制备班布特罗杂质c的方法 |
| GB201714734D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
| GB201714736D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
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| GB201714740D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
| CN109942462B (zh) * | 2019-03-06 | 2022-01-14 | 宏冠生物药业有限公司 | 一种盐酸班布特罗的合成工艺 |
| GB201903832D0 (en) | 2019-03-20 | 2019-05-01 | Atrogi Ab | New compounds and methods |
| GB202205895D0 (en) | 2022-04-22 | 2022-06-08 | Atrogi Ab | New medical uses |
| WO2024153813A1 (en) | 2023-01-20 | 2024-07-25 | Atrogi Ab | Beta 2-adrenergic receptor agonists for treatment or prevention of muscle wasting |
| GB202302225D0 (en) | 2023-02-16 | 2023-04-05 | Atrogi Ab | New medical uses |
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| CN117586152A (zh) * | 2023-11-23 | 2024-02-23 | 黑龙江乌苏里江制药有限公司 | 一种盐酸班布特罗的制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE178032C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1961-01-01 | |||
| DE1643488U (de) | 1949-11-28 | 1952-09-11 | G E Hilge Fa | Brutgeraet. |
| DK85789C (da) | 1955-07-05 | 1958-06-30 | Cilag Ag | Fremgangsmåde til fremstilling af d,1- eller 1-isopropyl-aminometyl-(3,4-dihydroksy-fenyl)-karbinol eller salte deraf. |
| DE1768167U (de) | 1958-04-02 | 1958-06-04 | Artur O Herrmann | Warngeraet bei strassenhindernissen. |
| DE1275069B (de) | 1960-02-15 | 1968-08-14 | Boehringer Sohn Ingelheim | 1-(3', 5'-Dihydroxyphenyl)-1-hydroxy-2-isopropylaminoalkane und Verfahren zu ihrer Herstellung |
| BE622434A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1961-09-14 | |||
| FR1324857A (fr) * | 1962-06-14 | 1963-04-19 | Chemie Linz Ag | Procédé pour la préparation de dérivés de la phényléthanolamine |
| GB1141606A (en) | 1965-04-12 | 1969-01-29 | Rech S Et D Applic Scient Et M | Improvements in alkyl ethers of substituted phenylaminoethanols |
| DE1543372A1 (de) | 1966-10-18 | 1971-04-01 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von o-substituierten 3,4-Dioxyphenylalkanolaminen |
| NO132866C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1966-10-19 | 1976-01-21 | Draco Ab | |
| SE358633B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1966-10-19 | 1973-08-06 | Draco Ab | |
| SE335359B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1966-10-19 | 1971-05-24 | Draco Ab | |
| US3937838A (en) * | 1966-10-19 | 1976-02-10 | Aktiebolaget Draco | Orally active bronchospasmolytic compounds and their preparation |
| FR6087M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1967-01-10 | 1968-06-04 | ||
| SE369299B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1967-10-18 | 1974-08-19 | Draco Ab | |
| SE338324B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1967-12-19 | 1971-09-06 | Haessle Ab | |
| NO129903B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1969-04-01 | 1974-06-10 | Sterling Drug Inc | |
| AT294046B (de) | 1969-07-08 | 1971-11-10 | Chemie Linz Ag | Verfahren zur Herstellung des N,N'-Bis[2-(3',4'-dihydroxyphenyl)-2-hydroxyäthyl]-hexamethylendiamins, seiner optisch aktiven Formen und der Salze derselben |
| US3657319A (en) * | 1970-05-05 | 1972-04-18 | Smith Kline French Lab | Alpha-aminoalkyl-4-hydroxy-3-carboalkoxyaminobenzyl alcohols |
| NO126437B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-08-05 | 1973-02-05 | Draco Ab | |
| NL7112938A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-09-30 | 1972-04-05 | ||
| CH550771A (de) | 1970-10-30 | 1974-06-28 | Hoffmann La Roche | Verfahren zur herstellung von phenaethylaminderivaten. |
| US3876679A (en) | 1970-12-09 | 1975-04-08 | Aldrich Chem Co Inc | Di-substituted phenethylcarbamic acid esters |
| FI55988C (fi) | 1971-10-19 | 1979-11-12 | Klinge Co Chem Pharm Fab | Foerfarande foer framstaellning av terapeutiskt anvaendbara o-acylfenoletanolaminer |
| US4011258A (en) | 1973-06-21 | 1977-03-08 | Aktiebolaget Draco | Orally active bronchospasmolytic compounds |
| FI56673C (fi) | 1974-03-29 | 1981-02-04 | Huhtamaeki Yhthymae Oy | Nytt foerfarande foer framstaellning av alfa-tert-bytylaminometyl-4-hydroxy-m-xylen-alfa1 alfa3-diol |
| JPS556625B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-05-16 | 1980-02-18 | ||
| US4063025A (en) * | 1975-02-05 | 1977-12-13 | Yamanouchi Pharmaceutical Co., Ltd. | 4-Substituted amino-α-aminomethylbenzyl alcohol derivatives |
| SE7510988L (sv) | 1975-10-01 | 1977-04-02 | Draco Ab | Nya farmaceutiskt aktiva foreningar |
| DE2710997C3 (de) * | 1977-03-14 | 1980-08-14 | Dr. Karl Thomae Gmbh, 7950 Biberach | 4-Alkoxy carbonylamino-phenyläthanolamine, deren Herstellung und deren Verwendung als Arzneimittel |
-
1981
- 1981-06-30 AT AT81850117T patent/ATE7689T1/de active
- 1981-06-30 CY CY1273A patent/CY1273A/xx unknown
- 1981-06-30 DE DE8181850117T patent/DE3163871D1/de not_active Expired
- 1981-06-30 EP EP81850117A patent/EP0043807B1/en not_active Expired
- 1981-07-01 US US06/279,672 patent/US4419364A/en not_active Expired - Lifetime
- 1981-07-07 NZ NZ197628A patent/NZ197628A/en unknown
- 1981-07-07 NO NO812311A patent/NO152130C/no unknown
- 1981-07-07 AU AU72618/81A patent/AU539976B2/en not_active Expired
- 1981-07-07 IE IE1522/81A patent/IE51373B1/en not_active IP Right Cessation
- 1981-07-07 PH PH25872A patent/PH16535A/en unknown
- 1981-07-08 HU HU811986A patent/HU184959B/hu unknown
- 1981-07-08 SU SU813308249A patent/SU1128830A3/ru active
- 1981-07-08 IS IS2657A patent/IS1262B6/is unknown
- 1981-07-08 HU HU813788A patent/HU187611B/hu unknown
- 1981-07-08 ES ES503768A patent/ES8300678A1/es not_active Expired
- 1981-07-08 FI FI812158A patent/FI73666C/fi not_active IP Right Cessation
- 1981-07-08 CA CA000381360A patent/CA1180021A/en not_active Expired
- 1981-07-08 DK DK303481A patent/DK157678C/da active
- 1981-07-08 PL PL1981232108A patent/PL128513B1/pl unknown
- 1981-07-08 PT PT73336A patent/PT73336B/pt unknown
- 1981-07-08 CS CS815265A patent/CS221845B2/cs unknown
- 1981-07-09 YU YU1704/81A patent/YU42116B/xx unknown
- 1981-07-09 GR GR65453A patent/GR74291B/el unknown
- 1981-07-09 KR KR1019810002490A patent/KR850000301B1/ko not_active Expired
- 1981-07-09 DD DD81231626A patent/DD202001A5/de unknown
-
1982
- 1982-06-15 ES ES513109A patent/ES513109A0/es active Granted
- 1982-06-15 ES ES513108A patent/ES513108A0/es active Granted
- 1982-07-06 US US06/395,650 patent/US4451663A/en not_active Expired - Lifetime
- 1982-07-23 PH PH27617A patent/PH19447A/en unknown
-
1983
- 1983-04-15 YU YU863/83A patent/YU43168B/xx unknown
- 1983-04-15 YU YU864/83A patent/YU43169B/xx unknown
-
1984
- 1984-09-26 KR KR1019840005924A patent/KR850000870B1/ko not_active Expired
- 1984-09-26 KR KR1019840005925A patent/KR850000871B1/ko not_active Expired
- 1984-11-09 SG SG797/84A patent/SG79784G/en unknown
-
1985
- 1985-01-17 HK HK53/85A patent/HK5385A/en not_active IP Right Cessation
-
1987
- 1987-12-30 MY MY26/87A patent/MY8700026A/xx unknown
-
1992
- 1992-06-24 MX MX9203239A patent/MX9203239A/es unknown
-
1993
- 1993-06-16 LU LU88304C patent/LU88304I2/fr unknown
-
1996
- 1996-06-27 NO NO1996008C patent/NO1996008I1/no unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MA | Patent expired |
Owner name: AKTIEBOLAGET DRACO |