FI72524C - Foerfarande foer framstaellning av farmakologiskt effektiva 3,6-diaminoakridinderivat. - Google Patents

Foerfarande foer framstaellning av farmakologiskt effektiva 3,6-diaminoakridinderivat. Download PDF

Info

Publication number
FI72524C
FI72524C FI820650A FI820650A FI72524C FI 72524 C FI72524 C FI 72524C FI 820650 A FI820650 A FI 820650A FI 820650 A FI820650 A FI 820650A FI 72524 C FI72524 C FI 72524C
Authority
FI
Finland
Prior art keywords
water
precipitate
mixture
acetone
solution
Prior art date
Application number
FI820650A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI820650L (fi
FI72524B (fi
Inventor
Istvan Csernus
Antal Kovacs
Janos Erdei
Andras Liptak
Pal Nanasi
Lorant Janossy
Istvan Kaszab
Kalman Polya
Andras Neszmelyi
Original Assignee
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar
Publication of FI820650L publication Critical patent/FI820650L/fi
Application granted granted Critical
Publication of FI72524B publication Critical patent/FI72524B/fi
Publication of FI72524C publication Critical patent/FI72524C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI820650A 1981-02-27 1982-02-25 Foerfarande foer framstaellning av farmakologiskt effektiva 3,6-diaminoakridinderivat. FI72524C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU47481 1981-02-27
HU81474A HU186383B (en) 1981-02-27 1981-02-27 Process for producing new citostatic amni-acridie-alpha, beta-bracket-d-bracket closed, or aracket-l-bracket closed-n-glycoside derivatives and salts

Publications (3)

Publication Number Publication Date
FI820650L FI820650L (fi) 1982-08-28
FI72524B FI72524B (fi) 1987-02-27
FI72524C true FI72524C (fi) 1987-06-08

Family

ID=10949743

Family Applications (1)

Application Number Title Priority Date Filing Date
FI820650A FI72524C (fi) 1981-02-27 1982-02-25 Foerfarande foer framstaellning av farmakologiskt effektiva 3,6-diaminoakridinderivat.

Country Status (27)

Country Link
US (1) US4462993A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS57197296A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR850001937B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT380481B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU554994B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE892293A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH649560A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD202033A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3207021A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK87682A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES509958A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI72524C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2500837B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2096135B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU186383B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL65093A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN156122B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1219970B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL8200791A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ199851A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH20206A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL136298B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RO (1) RO82961B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE457450B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU1346045A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU44673B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA821293B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU188856B (en) * 1983-03-23 1986-05-28 Biogal Gyogyszergyar,Hu Compositions for the regulation of plant growth and development comprising 3,6-diamino-acridine-n-glycoside-derivative as active substance
HU203896B (en) * 1988-10-26 1991-10-28 Biogal Gyogyszergyar Process for producing glycosides of aromatic amines
US5472582A (en) * 1993-04-23 1995-12-05 Astromed Limited Analysis of carbohydrates using 2-aminoacridone
FR2704856B1 (fr) * 1993-05-04 1995-08-04 Pf Medicament Nouveaux dérivés de la diméthylamino-3 acridine.
WO2025076406A1 (en) * 2023-10-05 2025-04-10 Collaborations Pharmaceuticals, Inc. Synthesis and evaluation of 9-aminoacridines with sars-cov-2 antiviral activity

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1008625A (en) * 1963-12-09 1965-11-03 Farmaceutyczna Spoldzielnia Pr Ascorbic acid derivative
DE1620473C3 (de) * 1964-05-25 1980-03-20 Starogardzkie Zaklady Farmaceutyczne Polfa Przedsiebiorstwo Panstwowe, Starogard Gdanski (Polen) Verfahren zur Herstellung von 1 -Nitro-9-(3'-dimethylaminopropylamino)-acridin-dihydrochlorid
PL106752B1 (pl) * 1976-02-25 1980-01-31 Politechnika Gdanska Sposob otrzymywania nowych 1-nitro-9-alkiloaminoalkiloaminoakrydyn lub ich soli
PL101032B1 (pl) * 1976-04-06 1978-11-30 Sposob otrzymywania 1-nitro-9-dwualkilo-aminoizoalkiloamiroakrydyn lub ich soli
US4314061A (en) * 1979-10-31 1982-02-02 Murdock Keith C Certain 3,6-bis-(heteroaminoalkoxy) acridines
US4335244A (en) * 1979-11-30 1982-06-15 Bristol-Myers Company Monolactate salts of 4'-(9-acridinylamino)methanesulfon-m-anisidide
US4322424A (en) * 1980-01-24 1982-03-30 Bristol-Myers Company Crystalline glucoconate salt of m-AMSA and compositions containing same

Also Published As

Publication number Publication date
AT380481B (de) 1986-05-26
IL65093A (en) 1985-11-29
US4462993A (en) 1984-07-31
GB2096135B (en) 1984-12-19
ATA73382A (de) 1985-10-15
HU186383B (en) 1985-07-29
PL235248A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1982-10-25
IN156122B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1985-05-18
YU44673B (en) 1990-12-31
FI820650L (fi) 1982-08-28
IT1219970B (it) 1990-05-24
GB2096135A (en) 1982-10-13
IL65093A0 (en) 1982-04-30
PH20206A (en) 1986-10-20
DK87682A (da) 1982-08-28
PL136298B1 (en) 1986-02-28
RO82961A (ro) 1984-01-14
KR830009137A (ko) 1983-12-17
IT8219887A0 (it) 1982-02-26
KR850001937B1 (ko) 1985-12-31
YU43582A (en) 1986-04-30
FI72524B (fi) 1987-02-27
JPS57197296A (en) 1982-12-03
FR2500837B1 (fr) 1985-06-28
CH649560A5 (de) 1985-05-31
DE3207021C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1991-01-17
FR2500837A1 (fr) 1982-09-03
AU554994B2 (en) 1986-09-11
SE457450B (sv) 1988-12-27
DE3207021A1 (de) 1982-09-23
AU8093382A (en) 1982-09-02
RO82961B (ro) 1984-01-30
SU1346045A3 (ru) 1987-10-15
BE892293A (fr) 1982-08-26
NL8200791A (nl) 1982-09-16
NZ199851A (en) 1985-03-20
DD202033A5 (de) 1983-08-24
ES8303446A1 (es) 1983-02-01
ES509958A0 (es) 1983-02-01
ZA821293B (en) 1983-04-27
SE8201229L (sv) 1982-08-28

Similar Documents

Publication Publication Date Title
US4720543A (en) 1a-7-substituted derivatives of mitomycin and uses thereof
US4658058A (en) 11-O-methylspergualin
DK145200B (da) Fremgangsmaade til fremstilling af anthtacyclinglycosid-antibiotika
JP2783722B2 (ja) スピカマイシン誘導体およびそれを含む抗腫瘍剤
FI72524C (fi) Foerfarande foer framstaellning av farmakologiskt effektiva 3,6-diaminoakridinderivat.
EP0014853A1 (en) Anthracycline derivatives, a process for their preparation and pharmaceutical compositions containing them
US4066753A (en) Neomycin and paromomycin derivatives
US4351937A (en) N-Glycosyl derivatives of anthracycline antibiotics and the method of their preparation
FI89494C (fi) Foerfarande foer framstaellning av nya sackaridderivat
FI83422C (fi) Foerfarande foer framstaellning av tumoerbekaempande antibiotika bbm-1675c och bbm-1675d.
US4410459A (en) Process for preparation of cytostatic compounds
US4347249A (en) Class of seco bis-indolic compounds which can be used as drugs and a process for the preparation thereof
FI57596B (fi) Foerfarande foer framstaellning av 3',4'-dideoxikanamycin b som aer antibakteriell och speciellt aktiv mot infektioner orsakade av kanamycinresistenta organismer
CA1327037C (en) Mitomycin derivatives having reduced bone marrow toxicity, processes for their preparation, and the uses thereof
AU656137B2 (en) Mitomycin derivatives having reduced bone marrow toxicity, processes for their preparation, and the uses thereof
Takai et al. Synthesis and antitumor activity of analogs of the antitumor antibiotic chartreusin
Pascual et al. Biosourced Au (III) Complexes from D‐Xylose: Synthesis and Biological Evaluation
NL8301792A (nl) Anthracycline-glycosiden.
EP0284380A1 (en) Mitomycin Derivatives
GB2085882A (en) Aprosamine derivatives
HU210499B (en) Process for preparing 6-o-alkylelsamicin a deriv.s and pharmaceutical compn.s contg. them
US4439602A (en) Nogalamycin derivatives
US4318790A (en) Photochemical process for preparing N-demethyl-derivatives of nogalamycin
US4921700A (en) BBM-1675c and d antitumor antibiotics
US4767847A (en) Nobamycin its analogs and process therefore

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: BIOGAL GYOGYSZERGYAR RT.