FI69847C - Nytt foerfarande foer framstaellning av 7-(substituerad)amino-3-substituerad-tiometyl- 3-cefem-karboxylsyror - Google Patents

Nytt foerfarande foer framstaellning av 7-(substituerad)amino-3-substituerad-tiometyl- 3-cefem-karboxylsyror Download PDF

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Publication number
FI69847C
FI69847C FI780367A FI780367A FI69847C FI 69847 C FI69847 C FI 69847C FI 780367 A FI780367 A FI 780367A FI 780367 A FI780367 A FI 780367A FI 69847 C FI69847 C FI 69847C
Authority
FI
Finland
Prior art keywords
group
amino
acid
cephem
ester
Prior art date
Application number
FI780367A
Other languages
English (en)
Finnish (fi)
Other versions
FI780367A (fi
FI69847B (fi
Inventor
Isamu Saikawa
Shuntaro Takano
Kaishu Momonoi
Isamu Takakura
Seietsu Kuroda
Kiyoshi Tanaka
Kenshin Hayashi
Bunei Nagahashi
Chiaki Kutani
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP52012182A external-priority patent/JPS6022718B2/ja
Priority claimed from JP52139840A external-priority patent/JPS6022719B2/ja
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of FI780367A publication Critical patent/FI780367A/fi
Application granted granted Critical
Publication of FI69847B publication Critical patent/FI69847B/fi
Publication of FI69847C publication Critical patent/FI69847C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI780367A 1977-02-08 1978-02-06 Nytt foerfarande foer framstaellning av 7-(substituerad)amino-3-substituerad-tiometyl- 3-cefem-karboxylsyror FI69847C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP1218277 1977-02-08
JP52012182A JPS6022718B2 (ja) 1977-02-08 1977-02-08 ７−アミノ−３−置換チオメチルセフエムカルボン酸類の新規製造法
JP52139840A JPS6022719B2 (ja) 1977-11-24 1977-11-24 ７−置換または非置換アミノ−３−置換チオメチルセフェムカルボン酸類の新規製造法
JP13984077 1977-11-24

Publications (3)

Publication Number Publication Date
FI780367A FI780367A (fi) 1978-08-09
FI69847B FI69847B (fi) 1985-12-31
FI69847C true FI69847C (fi) 1986-05-26

Family

ID=26347756

Family Applications (1)

Application Number Title Priority Date Filing Date
FI780367A FI69847C (fi) 1977-02-08 1978-02-06 Nytt foerfarande foer framstaellning av 7-(substituerad)amino-3-substituerad-tiometyl- 3-cefem-karboxylsyror

Country Status (12)

Country Link
US (2) US4317907A (sv)
AU (1) AU507813B2 (sv)
CA (1) CA1119586A (sv)
CH (1) CH638217A5 (sv)
DE (1) DE2804896C3 (sv)
DK (1) DK157760C (sv)
ES (1) ES466759A1 (sv)
FI (1) FI69847C (sv)
FR (1) FR2379540A1 (sv)
GB (1) GB1565941A (sv)
NL (1) NL174829C (sv)
SE (1) SE438676B (sv)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565941A (en) * 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
JPS5543043A (en) * 1978-09-22 1980-03-26 Sankyo Co Ltd Preparation of 3-substituted thiomethylcephalosporin derivative
EP0104671B1 (fr) * 1980-02-18 1990-05-23 Roussel-Uclaf Nouvelles oximes dérivées de l'acide 3-alkyloxy ou 3-alkylthiométhyl-7 amino thiazolylacétamido céphalosporaniques, leur préparation, leur application comme médicaments et les compositions les renfermant
FR2476087A1 (fr) * 1980-02-18 1981-08-21 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkyl-thiomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS56118085A (en) * 1980-02-25 1981-09-16 Takeda Chem Ind Ltd 2-methylcephalosporin derivative and its preparation
NZ198350A (en) * 1980-09-25 1985-02-28 Toyama Chemical Co Ltd Cephalosporins and intermediates;pharmaceutical compositions
EP0051824B1 (en) * 1980-11-11 1986-01-15 Takeda Chemical Industries, Ltd. Improvement in the method for producing 7-aminocephem compounds
FR2499995A1 (fr) * 1981-02-13 1982-08-20 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkylthiomethyl 7-amino thiazolylacetamido cephalosporanique, leur preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
JPS57169488A (en) * 1981-04-13 1982-10-19 Meiji Seika Kaisha Ltd Cephem compound and its preparation
US4472574A (en) * 1981-05-22 1984-09-18 Hoffman-La Roche Inc. Process for the manufacture of a cephem carboxylic acid derivative
EP0135683B1 (en) * 1981-09-10 1987-07-22 Takeda Chemical Industries, Ltd. Method for production of cephalosporin compounds
DE3224866A1 (de) * 1982-07-02 1984-01-05 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel
GR78718B (sv) * 1983-01-31 1984-09-27 Ici Pharma
AT383811B (de) * 1983-09-22 1987-08-25 Biochemie Gmbh Verfahren zur herstellung von monoalkalisalzen von 7-amino-3-cephem-4-carbonsaeurederivaten
AT384222B (de) * 1985-06-03 1987-10-12 Biochemie Gmbh Verfahren zur herstellung von 7-amino-3alkoxymethyl-3-cephem-4-carbonsaeuren
US4754761A (en) * 1985-07-05 1988-07-05 Critikon, Inc. Automated mean arterial blood pressure monitor with data enhancement
EP0225634B1 (en) * 1985-12-13 1994-04-06 Takeda Chemical Industries, Ltd. Antibacterial compounds, their production and use
JPS6466192A (en) * 1987-09-07 1989-03-13 Meiji Seika Kaisha Beta-lactams and their preparation
GB9115287D0 (en) * 1991-07-15 1991-08-28 Antibioticos Spa Process for the preparation of cephalosporins intermediates
KR100477763B1 (ko) * 2000-08-16 2005-03-21 주식회사 엔지켐 세파트리진 프로필렌글리콜 중간체의 신규한 제조방법
KR100432425B1 (ko) * 2000-11-16 2004-05-22 씨제이 주식회사 세펨 유도체 또는 그 염의 신규한 제조방법
AU2002310863A1 (en) 2001-04-19 2002-11-05 Bioferma Murcia, S.A. Enzymatic process for preparing cephalosporanic acid derivatives using alpha-ketoacid derivatives
US20030135041A1 (en) * 2002-01-04 2003-07-17 Orchid Chemicals & Pharmaceuticals Limited, India Synthesis of ceftiofur intermediate
US8198434B2 (en) * 2008-05-07 2012-06-12 Idexx Laboratories, Inc. Process for preparing cefsulodin sodium
CN101768168B (zh) * 2008-12-30 2013-05-22 上海新先锋药业有限公司 头孢中间体的合成方法
CN105541868B (zh) * 2015-12-30 2017-11-07 河南康达制药有限公司 一种7‑atca的制备工艺

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795484U (de) 1959-04-21 1959-09-10 Richard Langer Quertraeger fuer laengsdraehte zum abstuetzen von pflanzen, insbesondere weinreben.
NL130098C (sv) 1963-07-15
CH527215A (de) * 1967-04-15 1972-08-31 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten
GB1381272A (en) * 1971-01-26 1975-01-22 Glaxo Lab Ltd Cephalosporin compounds
JPS5116436B1 (sv) * 1971-05-31 1976-05-24
ZA728331B (en) 1971-12-23 1974-06-26 Lilly Co Eli Preparation of 3-alkylthiomethyl cephalosporins
US3840531A (en) * 1972-03-21 1974-10-08 Lilly Co Eli Process for preparing 7-(alpha-hydroxy-alpha-phenyl)acetamido-3-(1-methyl-1h-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and derivatives thereof
CA1015745A (en) 1972-06-27 1977-08-16 Fujisawa Pharmaceutical Co. 3-substituted-methyl-3-cephem-4-carboxylic acid derivatives and preparation thereof
DK635474A (sv) * 1974-02-05 1975-10-13 Ciba Geigy Ag
JPS5111782A (en) 1974-07-16 1976-01-30 Takeda Chemical Industries Ltd 77 aminosefuemujudotaino seizoho
CH605997A5 (sv) 1974-08-30 1978-10-13 Ciba Geigy Ag
GB1565941A (en) * 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
US4144391A (en) * 1977-03-07 1979-03-13 Eli Lilly And Company Cephalosporin displacement reaction

Also Published As

Publication number Publication date
DK55478A (da) 1978-08-09
AU3282378A (en) 1979-08-02
SE7801428L (sv) 1978-08-09
GB1565941A (en) 1980-04-23
DE2804896A1 (de) 1978-08-17
DE2804896C3 (de) 1982-06-09
DK157760B (da) 1990-02-12
CH638217A5 (de) 1983-09-15
CA1119586A (en) 1982-03-09
DK157760C (da) 1990-07-16
FI780367A (fi) 1978-08-09
FR2379540B1 (sv) 1981-07-31
NL174829B (nl) 1984-03-16
FR2379540A1 (fr) 1978-09-01
US4317907A (en) 1982-03-02
DE2804896B2 (de) 1980-07-24
NL7801382A (nl) 1978-08-10
SE438676B (sv) 1985-04-29
US4385178A (en) 1983-05-24
FI69847B (fi) 1985-12-31
AU507813B2 (en) 1980-02-28
ES466759A1 (es) 1978-10-01
NL174829C (nl) 1984-08-16

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MA Patent expired
MA Patent expired

Owner name: TOYAMA CHEMICAL CO. LTD.