FI69456C - Foerfarande foer framstaellning av antiallergiska 4-substituerade tiazol-2-oxamsyror och deras salter och estrar - Google Patents

Foerfarande foer framstaellning av antiallergiska 4-substituerade tiazol-2-oxamsyror och deras salter och estrar Download PDF

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Publication number
FI69456C
FI69456C FI792006A FI792006A FI69456C FI 69456 C FI69456 C FI 69456C FI 792006 A FI792006 A FI 792006A FI 792006 A FI792006 A FI 792006A FI 69456 C FI69456 C FI 69456C
Authority
FI
Finland
Prior art keywords
thiazole
acid
oxamic acid
group
oxamic
Prior art date
Application number
FI792006A
Other languages
English (en)
Finnish (fi)
Other versions
FI69456B (fi
FI792006A (fi
Inventor
Friedrich Karl Hess
Patrick Brian Stewart
James Thomas Oliver
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of FI792006A publication Critical patent/FI792006A/fi
Application granted granted Critical
Publication of FI69456B publication Critical patent/FI69456B/fi
Publication of FI69456C publication Critical patent/FI69456C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI792006A 1978-06-27 1979-06-25 Foerfarande foer framstaellning av antiallergiska 4-substituerade tiazol-2-oxamsyror och deras salter och estrar FI69456C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2828091 1978-06-27
DE19782828091 DE2828091A1 (de) 1978-06-27 1978-06-27 4-substituierte thiazoloxamsaeuren sowie ihre salze und ester

Publications (3)

Publication Number Publication Date
FI792006A FI792006A (fi) 1979-12-28
FI69456B FI69456B (fi) 1985-10-31
FI69456C true FI69456C (fi) 1986-02-10

Family

ID=6042852

Family Applications (1)

Application Number Title Priority Date Filing Date
FI792006A FI69456C (fi) 1978-06-27 1979-06-25 Foerfarande foer framstaellning av antiallergiska 4-substituerade tiazol-2-oxamsyror och deras salter och estrar

Country Status (36)

Country Link
US (1) US4238496A (fr)
JP (1) JPS557290A (fr)
AT (1) AT373884B (fr)
AU (1) AU525312B2 (fr)
BE (1) BE877293A (fr)
BG (1) BG30324A3 (fr)
CA (1) CA1246071A (fr)
CH (1) CH644370A5 (fr)
CS (1) CS208114B2 (fr)
DD (1) DD144542A5 (fr)
DE (1) DE2828091A1 (fr)
DK (1) DK147940C (fr)
ES (1) ES481917A1 (fr)
FI (1) FI69456C (fr)
FR (1) FR2429787A1 (fr)
GB (1) GB2023580B (fr)
GR (1) GR69231B (fr)
HK (1) HK66285A (fr)
HU (1) HU178996B (fr)
IE (1) IE48357B1 (fr)
IL (1) IL57659A0 (fr)
IT (1) IT1120443B (fr)
LU (1) LU81424A1 (fr)
MY (1) MY8600653A (fr)
NL (1) NL7904957A (fr)
NO (1) NO151500C (fr)
NZ (1) NZ190842A (fr)
PH (1) PH17226A (fr)
PL (1) PL117333B1 (fr)
PT (1) PT69822A (fr)
RO (1) RO77553A (fr)
SE (1) SE446182B (fr)
SG (1) SG61985G (fr)
SU (1) SU791237A3 (fr)
YU (1) YU41645B (fr)
ZA (1) ZA793176B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4321372A (en) * 1980-06-16 1982-03-23 Pfizer Inc. Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides
DE3027528A1 (de) * 1980-07-19 1982-02-18 Basf Ag, 6700 Ludwigshafen Ueberbrueckte thiazolyloxamidsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
DE3027527A1 (de) 1980-07-19 1982-02-18 Basf Ag, 6700 Ludwigshafen Neue oxamidsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
FR2494272A1 (fr) * 1980-11-19 1982-05-21 Fabre Sa Pierre Derives de l'acide thiazolyl-2 oxamique substitues en position 4 par un radical thienyle ou furyle, leur preparation et leur utilisation comme medicaments
DE3135250A1 (de) * 1981-09-05 1983-03-17 Basf Ag, 6700 Ludwigshafen Tricyclische thiazolyloxamate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
US4788198A (en) * 1983-09-01 1988-11-29 Boehringer Ingelheim Pharmaceuticals, Inc. Diazine-ethyenylphenyl oxamic acids and esters and salts thereof
ATE38224T1 (de) * 1983-09-01 1988-11-15 Boehringer Ingelheim Ltd Diazin-ethenylphenyloxamidsaeuren und deren ester und salze.
US4681884A (en) * 1983-09-01 1987-07-21 Boehringer Ingelheim Pharmaceuticals, Inc. Diazine-ethenylphenyl oxamic acids and esters and salts thereof
IT1204959B (it) * 1987-03-25 1989-03-10 Zambon Farmaceutici Spa Composti dotati di attivita' antiallergica
IT1204960B (it) * 1987-03-25 1989-03-10 Zambon Farmaceutici Spa Composti dotati di attivita' antiallergica
DE3807232A1 (de) * 1988-03-05 1989-09-14 Bayer Ag Substituierte acrylsaeureester
JPH0667836B2 (ja) * 1989-03-01 1994-08-31 東洋紡績株式会社 アミド系化合物からなる抗アレルギー剤
FR2671552B1 (fr) * 1991-01-15 1993-05-07 Pf Medicament Procede de preparation de thiazolyl-2 oxamates d'alkyle.
DE69821132T2 (de) * 1997-10-27 2004-10-21 Takeda Chemical Industries Ltd 1,3-thiazole als adenosine a3 rezeptor antagonisten zur behandlung von asthma, allergien und diabetes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1062245B (de) * 1957-10-17 1959-07-30 Ciba Geigy Verfahren zur Herstellung von 2-Amino-4-pyridyl-(2')-thiazol und seinen Salzen
FR1526074A (fr) * 1967-03-22 1968-05-24 Rech S Ind S O R I Soc D Méthoxy-phényl-amino-2-thiazoles, leurs amides et leurs procédés de préparation
BE795907A (fr) * 1972-02-25 1973-06-18 Luso Farmaco Inst 2-amino-4-arylthiazoles 5-substitues et leur preparation
US3966965A (en) * 1973-03-23 1976-06-29 American Home Products Corporation Oxamic acid derivatives for the prevention of immediate type hypersensitivity reactions
US4054666A (en) * 1973-03-23 1977-10-18 American Home Products Corporation Compositions and methods of treating immediate hypersensitivity reactions with thiazolyl oxamic acid derivatives
FR2429210A1 (fr) * 1978-06-19 1980-01-18 Fabre Sa Pierre Derives de phenyl-4 thiazolyl-2 oxamates utiles dans le traitement de l'asthme

Also Published As

Publication number Publication date
CA1246071A (fr) 1988-12-06
GB2023580B (en) 1982-08-25
YU149779A (en) 1982-10-31
FR2429787A1 (fr) 1980-01-25
CS208114B2 (en) 1981-08-31
BE877293A (fr) 1979-12-27
HU178996B (en) 1982-07-28
IE48357B1 (en) 1984-12-26
PH17226A (en) 1984-07-03
DK147940C (da) 1985-09-02
PL117333B1 (en) 1981-07-31
IL57659A0 (en) 1979-10-31
SG61985G (en) 1986-05-02
DE2828091C2 (fr) 1988-05-26
IT7949533A0 (it) 1979-06-25
PT69822A (de) 1979-07-01
ZA793176B (en) 1981-03-25
GB2023580A (en) 1980-01-03
US4238496A (en) 1980-12-09
AU525312B2 (en) 1982-10-28
BG30324A3 (en) 1981-05-15
NO792139L (no) 1979-12-28
JPS557290A (en) 1980-01-19
SU791237A3 (ru) 1980-12-23
LU81424A1 (de) 1980-07-21
JPS6356225B2 (fr) 1988-11-07
DK269879A (da) 1979-12-28
RO77553A (fr) 1982-02-01
HK66285A (en) 1985-09-13
SE446182B (sv) 1986-08-18
DE2828091A1 (de) 1980-01-10
NL7904957A (nl) 1980-01-02
FR2429787B1 (fr) 1982-12-31
NZ190842A (en) 1981-01-23
AU4839779A (en) 1980-01-03
DK147940B (da) 1985-01-14
NO151500B (no) 1985-01-07
ATA431879A (de) 1983-07-15
IE791200L (en) 1979-12-27
CH644370A5 (de) 1984-07-31
MY8600653A (en) 1986-12-31
PL216608A1 (fr) 1980-03-24
YU41645B (en) 1987-12-31
GR69231B (fr) 1982-05-10
AT373884B (de) 1984-02-27
FI69456B (fi) 1985-10-31
IT1120443B (it) 1986-03-26
FI792006A (fi) 1979-12-28
DD144542A5 (de) 1980-10-22
NO151500C (no) 1985-04-24
ES481917A1 (es) 1980-02-16
SE7905608L (sv) 1979-12-28

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Owner name: C.H. BOEHRINGER SOHN