FI67687C - Foerfarande foer framstaellning av nya terapeutiskt godtagbaraglycerolderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt godtagbaraglycerolderivat Download PDF

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Publication number
FI67687C
FI67687C FI782518A FI782518A FI67687C FI 67687 C FI67687 C FI 67687C FI 782518 A FI782518 A FI 782518A FI 782518 A FI782518 A FI 782518A FI 67687 C FI67687 C FI 67687C
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Finland
Prior art keywords
glycerol
group
hexadecyl
carbon atoms
formula
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FI782518A
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English (en)
Finnish (fi)
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FI67687B (fi
FI782518A (fi
Inventor
Allen Richard Kraska
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Pfizer
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Publication of FI782518A publication Critical patent/FI782518A/fi
Priority to FI841878A priority Critical patent/FI841878A/fi
Priority to FI841877A priority patent/FI841877A/fi
Publication of FI67687B publication Critical patent/FI67687B/fi
Application granted granted Critical
Publication of FI67687C publication Critical patent/FI67687C/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/15—Unsaturated ethers containing only non-aromatic carbon-to-carbon double bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/44—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reduction and hydrolysis of nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/02—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen
    • C07C47/198—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Claims (3)

1 I R2-0-CH τ~ 40 67687 jossa , R2 ja Y tarkoittavat samaa kuin edellä, pelkistetään, ja haluttaessa saatu kaava I tai II mukainen yhdiste, jossa R^ on vety, alkyloidaan tai saatu kaavan I tai II mukainen yhdiste muutetaan farmaseuttisesti hyväksyttäväksi happoadditiosuolaksi. 41 67687 Förfarande för framställning av terapeutiskt användbara glyce-rolderivat med formlerna I och II och farmaseutiskt godtagbara syra-additionssalter därav, R„-0-CH~
1 I 2 CH-O-Y-NHR. I I 3 r2-o-ch2 ch_-o-y-nhrq R.-O-CH II 1. r2-o-ch2 i vilka formler R^ och R2 betecknar oberoende av varandra en normal-alkylgrupp med 12-20 kolatomer eller en normalalkenylgrupp med 12-20 kolatomer, vilken inte har en dubbelbindning i 1-ställning, Y är en alkylengrupp med 2-4 kolatomer, varvid de bäda valenserna är i olika kolatomer, eller en fenyldimetylengrupp med formeln in CH CH-> &·- ' cfL,- ·“" Φ • CH2 eller en grupp med formeln där q är ett heltal 1-3 och den vänstra bindningen är bunden tili O-atomen och R3 är väte eller en alkylgrupp med 2-4 kolatomer, kännetecknat därav, att a) en förening med formeln 67687 42 R1-0-CH2 CH-0~Y *-CN VI R2-0-CH2 eller CH--0-Y1-CN I 2 R1-°-CH VII r2-o-ch2 där R^ och r2 betecknar samma som ovan och Y' är en alkylengrupp med 1-3 kolatomer, en grupp med formeln där den vänstra bindningen Sr bunden till O-atomen, eller en grupp med formeln där den vänstra bindningen Sr bunden till O-atomen, reduceras, eller b) en förening med formeln R.-O-CH- 1 i 2 CH-O-Y-N- VIII i 3 r2-o-ch2 eller CH-O-Y-N i 2 3 R„-O-CH IX
1 I r2-o-ch II
FI782518A 1977-08-18 1978-08-17 Foerfarande foer framstaellning av nya terapeutiskt godtagbaraglycerolderivat FI67687C (fi)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI841878A FI841878A (fi) 1977-08-18 1984-05-10 Foerfarande foer framstaellning av terapeutiskt anvaendbara glycerolderivat.
FI841877A FI841877A (fi) 1977-08-18 1984-05-10 Foerfarande foer framstaellning av terapeutiskt anvaendbara propandiolderivat.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/825,535 US4166132A (en) 1977-08-18 1977-08-18 Antiviral amine derivatives of glycerol and propanediols
US82553577 1977-08-18

Publications (3)

Publication Number Publication Date
FI782518A FI782518A (fi) 1979-02-19
FI67687B FI67687B (fi) 1985-01-31
FI67687C true FI67687C (fi) 1985-05-10

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ID=25244254

Family Applications (1)

Application Number Title Priority Date Filing Date
FI782518A FI67687C (fi) 1977-08-18 1978-08-17 Foerfarande foer framstaellning av nya terapeutiskt godtagbaraglycerolderivat

Country Status (35)

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US (1) US4166132A (sv)
JP (3) JPS5829939B2 (sv)
AR (2) AR219543A1 (sv)
AT (1) AT363922B (sv)
AU (1) AU503079B1 (sv)
BE (1) BE869793A (sv)
CA (1) CA1102354A (sv)
CH (1) CH634544A5 (sv)
CS (1) CS208155B2 (sv)
DD (2) DD143902A5 (sv)
DE (3) DE2835369C2 (sv)
DK (1) DK149022C (sv)
EG (1) EG13438A (sv)
ES (3) ES472659A1 (sv)
FI (1) FI67687C (sv)
FR (2) FR2421871A1 (sv)
GB (1) GB2005248B (sv)
GR (1) GR73154B (sv)
HU (2) HU177884B (sv)
IE (1) IE47151B1 (sv)
IL (1) IL55370A (sv)
IN (1) IN148386B (sv)
IT (1) IT1098280B (sv)
LU (1) LU80114A1 (sv)
MX (1) MX6091E (sv)
NL (1) NL176670C (sv)
NO (3) NO147300C (sv)
NZ (1) NZ188174A (sv)
PH (4) PH16469A (sv)
PL (3) PL116434B1 (sv)
PT (1) PT68426A (sv)
SE (3) SE447823B (sv)
SU (3) SU893128A3 (sv)
YU (3) YU41115B (sv)
ZA (1) ZA783855B (sv)

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US7622541B2 (en) * 2003-01-17 2009-11-24 The United States Of America As Represented By The Secretary Of The Navy Polyurethane coating
US7615604B2 (en) * 2003-01-17 2009-11-10 The United States Of America As Represented By The Secretary Of The Navy Diols formed by ring-opening of epoxies
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Also Published As

Publication number Publication date
NO147300B (no) 1982-12-06
FI67687B (fi) 1985-01-31
SU906363A3 (ru) 1982-02-15
GB2005248B (en) 1982-03-24
JPS5829939B2 (ja) 1983-06-25
DE2835369A1 (de) 1979-02-22
PL115777B1 (en) 1981-04-30
ES479616A1 (es) 1979-08-01
ZA783855B (en) 1979-07-25
PL116119B1 (en) 1981-05-30
DD143902A5 (de) 1980-09-17
JPS5924144B2 (ja) 1984-06-07
NO154344B (no) 1986-05-26
FR2414038A1 (fr) 1979-08-03
PT68426A (en) 1978-09-01
EG13438A (en) 1981-12-31
SE8401849D0 (sv) 1984-04-03
IL55370A (en) 1981-11-30
NO782791L (no) 1979-02-20
AU503079B1 (en) 1979-08-23
LU80114A1 (fr) 1980-04-21
DD148951A5 (de) 1981-06-17
IT7826813A0 (it) 1978-08-17
HU181238B (en) 1983-06-28
NO813324L (no) 1979-02-20
IL55370A0 (en) 1978-10-31
US4166132A (en) 1979-08-28
NO147670C (no) 1983-05-25
DK149022B (da) 1985-12-23
AT363922B (de) 1981-09-10
NL176670B (nl) 1984-12-17
ES472659A1 (es) 1979-10-16
FR2414038B1 (sv) 1982-07-02
SU893128A3 (ru) 1981-12-23
FI782518A (fi) 1979-02-19
ES479615A1 (es) 1979-08-01
CH634544A5 (fr) 1983-02-15
YU41115B (en) 1986-12-31
IE47151B1 (en) 1983-12-28
CS208155B2 (en) 1981-08-31
GB2005248A (en) 1979-04-19
NO147670B (no) 1983-02-14
SE8401849L (sv) 1984-04-03
SE8401850D0 (sv) 1984-04-03
PH18067A (en) 1985-03-18
DK321478A (da) 1979-02-19
DE2857416C2 (de) 1984-05-24
NO813325L (no) 1979-02-20
YU41277B (en) 1986-12-31
ATA600278A (de) 1981-02-15
YU41276B (en) 1986-12-31
DE2857415C2 (de) 1985-02-07
SE8401850L (sv) 1984-04-03
AR219543A1 (es) 1980-08-29
JPS57167966A (en) 1982-10-16
CA1102354A (en) 1981-06-02
HU177884B (en) 1982-01-28
NO147300C (no) 1983-03-16
PH18111A (en) 1985-03-22
PL209092A1 (pl) 1979-06-04
IN148386B (sv) 1981-02-07
IT1098280B (it) 1985-09-07
YU262982A (en) 1983-04-30
DK149022C (da) 1986-10-13
SE463456B (sv) 1990-11-26
SE7808701L (sv) 1979-02-19
AR218733A1 (es) 1980-06-30
DE2835369C2 (de) 1982-12-02
FR2421871B1 (sv) 1982-07-02
JPS5929582B2 (ja) 1984-07-21
SU850005A3 (ru) 1981-07-23
NZ188174A (en) 1984-07-31
NL176670C (nl) 1985-05-17
PH16469A (en) 1983-10-21
MX6091E (es) 1984-11-12
JPS57167913A (en) 1982-10-16
PH17789A (en) 1984-12-13
YU263082A (en) 1983-04-30
NO154344C (no) 1986-09-03
YU197478A (en) 1983-02-28
FR2421871A1 (fr) 1979-11-02
GR73154B (sv) 1984-02-13
IE781658L (en) 1979-02-18
SE447823B (sv) 1986-12-15
JPS5441807A (en) 1979-04-03
BE869793A (fr) 1979-02-19
NL7808565A (nl) 1979-02-20
PL116434B1 (en) 1981-06-30

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